People_

Dr Chunling Huang

NHMRC Early Career Fellow
Senior Research Fellow
Northern Clinical School
Faculty of Medicine and Health

Email

chunling.huang@sydney.edu.au

Themes

Obesity, Diabetes and Cardiovascular Disease

Keywords

Nephrology, Kidney disease

Approaches

Animal Models, Complications, Pathogenesis

Publications

By Type

Expand all

Journals

Cao, Q., Huang, C., Yi, H., Gill, A., Chou, A., Foley, M., Hosking, C., Lim, K., Triffon, C., Shi, Y., Chen, X., Pollock, C. (2022). A single-domain i-body, AD-114, attenuates renal fibrosis through blockade of CXCR4. JCI Insight, 7(4), e143018. [More Information]
Bian, J., Liebert, A., Bicknell, B., Chen, X., Huang, C., Pollock, C. (2022). Faecal Microbiota Transplantation and Chronic Kidney Disease. Nutrients, 14(12). [More Information]
Huang, C., Chen, X., Pollock, C. (2022). KCa3.1 in diabetic kidney disease. Current Opinion In Nephrology And Hypertension, 31(1), 129-134. [More Information]
Cao, Q., Huang, C., Chen, X., Pollock, C. (2022). Mesenchymal Stem Cell-Derived Exosomes: Toward Cell-Free Therapeutic Strategies in Chronic Kidney Disease. Frontiers in Medicine, 9, 816656. [More Information]
Bian, J., Liebert, A., Bicknell, B., Chen, X., Huang, C., Pollock, C. (2022). Therapeutic Potential of Photobiomodulation for Chronic Kidney Disease. International Journal of Molecular Sciences, 23(14). [More Information]
Klionsky, D., Kamal Abdel-Aziz, A., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M., Abudu, Y., et al, Al-Akra, L., Bae, D., Dharmasivam, M., Huang, M., Kalinowski, D., Richardson, D., Chen, X., Hesselson, D., Huang, C., Leck, L., Stefan, S., Nguyen, L., Sahni, S., Sue, C., Zheng, G. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), 1-382. [More Information]
Huang, C., Yi, H., Shi, Y., Cao, Q., Shi, Y., Cheng, D., Braet, F., Chen, X., Pollock, C. (2021). KCa3.1 Mediates Dysregulation of Mitochondrial Quality Control in Diabetic Kidney Disease. Frontiers in Cell and Developmental Biology, 9, 573814. [More Information]
Yi, H., Huang, C., Shi, Y., Cao, Q., Chen, J., Chen, X., Pollock, C. (2021). Metformin Attenuates Renal Fibrosis in a Mouse Model of Adenine-Induced Renal Injury Through Inhibiting TGF-beta1 Signaling Pathways. Frontiers in Cell and Developmental Biology, 9, 603802. [More Information]
Huang, C., Bian, J., Cao, Q., Chen, X., Pollock, C. (2021). The mitochondrial kinase pink1 in diabetic kidney disease. International Journal of Molecular Sciences, 22(4), 1-14. [More Information]
Shi, Y., Huang, C., Yi, H., Cao, Q., Zhao, Y., Chen, J., Chen, X., Pollock, C. (2020). RIPK3 blockade attenuates kidney fibrosis in a folic acid model of renal injury. The FASEB Journal, 34(8), 10286-10298. [More Information]
Shi, Y., Huang, C., Zhao, Y., Cao, Q., Yi, H., Chen, X., Pollock, C. (2020). RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy. Scientific Reports, 10(1), 10458. [More Information]
Shi, Y., Chen, X., Huang, C., Pollock, C. (2020). RIPK3: A New Player in Renal Fibrosis. Frontiers in Cell and Developmental Biology, 8, 502. [More Information]
Cao, Q., Chen, X., Huang, C., Pollock, C. (2019). MicroRNA as novel biomarkers and therapeutic targets in diabetic kidney disease: An update. FASEB BioAdvances, 1(6), 375-388. [More Information]
Yi, H., Huang, C., Shi, Y., Cao, Q., Zhao, Y., Zhang, L., Chen, J., Pollock, C., Chen, X. (2018). Metformin attenuates folic-acid induced renal fibrosis in mice. Journal of Cellular Physiology, 233(9), 7045-7054. [More Information]
Huang, C., Zhang, L., Shi, Y., Yi, H., Zhao, Y., Chen, J., Pollock, C., Chen, X. (2018). The KCa3.1 blocker TRAM34 reverses renal damage in a mouse model of established diabetic nephropathy. PloS One, 13(2), 1-15. [More Information]
Huang, C., Lin, Z., Cheng, D., Braet, F., Pollock, C., Chen, X. (2016). KCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys via PI3k/Akt/mTOR signaling pathways. Scientific Reports, 6, 1-12. [More Information]
Peeters, M., Huang, C., Vonk, L., Lu, Z., Bank, R., Helder, M., Doulabi, B. (2016). Optimisation of high-quality total ribonucleic acid isolation from cartilaginous tissues for real-time polymerase chain reaction analysis. Bone & Joint Research, 5(11), 560-568. [More Information]
Huang, C., Zhang, Y., Kelly, D., Tan, C., Gill, A., Cheng, D., Braet, F., Park, J., Sue, C., Pollock, C., Chen, X. (2016). Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway. Scientific Reports, 6, 1-13. [More Information]
Huang, C., Pollock, C., Chen, X. (2015). KCa3.1: a new player in progressive kidney disease. Current Opinion In Nephrology And Hypertension, 24(1), 61-66. [More Information]
Huang, C., Pollock, C., Chen, X. (2014). High Glucose Induces CCL20 in Proximal Tubular Cells via Activation of the KCa3.1 Channel. PloS One, 9(4), 1-8. [More Information]
Huang, C., Day, M., Poronnik, P., Pollock, C., Chen, X. (2014). Inhibition of KCa3.1 suppresses TGF-Beta1 induced MCP-1 expression in human proximal tubular cells through Smad3, p38 and ERK1/2 signaling pathways. International Journal of Biochemistry and Cell Biology, 47(1), 1-10. [More Information]
Gangadharan Komala, M., Gross, S., Mudaliar, H., Huang, C., Pegg, K., Mather, A., Shen, S., Pollock, C., Panchapakesan, U. (2014). Inhibition of Kidney Proximal Tubular Glucose Reabsorption Does Not Prevent against Diabetic Nephropathy in Type 1 Diabetic eNOS Knockout Mice. PloS One, 9(11), 1-12. [More Information]
Huang, C., Shen, S., Ma, Q., Gill, A., Pollock, C., Chen, X. (2014). KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis. Nephrology Dialysis Transplantation, 29(2), 313-324. [More Information]
Huang, C., Pollock, C., Chen, X. (2014). Role of the potassium channel KCa3.1 in diabetic nephropathy. Clinical Science, 127(7), 423-433. [More Information]
Huang, C., Lin, M., Cheng, D., Braet, F., Pollock, C., Chen, X. (2014). Thioredoxin-interacting protein mediates dysfunction of tubular autophagy in diabetic kidneys through inhibiting autophagic flux. Laboratory Investigation, 94(3), 309-320. [More Information]
Huang, C., Shen, S., Ma, Q., Chen, J., Gill, A., Pollock, C., Chen, X. (2013). Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-Î²1/Smad Pathway in Diabetic Mice. Diabetes, 62(8), 2923-2934. [More Information]

show 23 more

By Year

Expand all

2022

Cao, Q., Huang, C., Yi, H., Gill, A., Chou, A., Foley, M., Hosking, C., Lim, K., Triffon, C., Shi, Y., Chen, X., Pollock, C. (2022). A single-domain i-body, AD-114, attenuates renal fibrosis through blockade of CXCR4. JCI Insight, 7(4), e143018. [More Information]
Bian, J., Liebert, A., Bicknell, B., Chen, X., Huang, C., Pollock, C. (2022). Faecal Microbiota Transplantation and Chronic Kidney Disease. Nutrients, 14(12). [More Information]
Huang, C., Chen, X., Pollock, C. (2022). KCa3.1 in diabetic kidney disease. Current Opinion In Nephrology And Hypertension, 31(1), 129-134. [More Information]
Cao, Q., Huang, C., Chen, X., Pollock, C. (2022). Mesenchymal Stem Cell-Derived Exosomes: Toward Cell-Free Therapeutic Strategies in Chronic Kidney Disease. Frontiers in Medicine, 9, 816656. [More Information]
Bian, J., Liebert, A., Bicknell, B., Chen, X., Huang, C., Pollock, C. (2022). Therapeutic Potential of Photobiomodulation for Chronic Kidney Disease. International Journal of Molecular Sciences, 23(14). [More Information]

show 2 more

2021

Klionsky, D., Kamal Abdel-Aziz, A., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M., Abudu, Y., et al, Al-Akra, L., Bae, D., Dharmasivam, M., Huang, M., Kalinowski, D., Richardson, D., Chen, X., Hesselson, D., Huang, C., Leck, L., Stefan, S., Nguyen, L., Sahni, S., Sue, C., Zheng, G. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), 1-382. [More Information]
Huang, C., Yi, H., Shi, Y., Cao, Q., Shi, Y., Cheng, D., Braet, F., Chen, X., Pollock, C. (2021). KCa3.1 Mediates Dysregulation of Mitochondrial Quality Control in Diabetic Kidney Disease. Frontiers in Cell and Developmental Biology, 9, 573814. [More Information]
Yi, H., Huang, C., Shi, Y., Cao, Q., Chen, J., Chen, X., Pollock, C. (2021). Metformin Attenuates Renal Fibrosis in a Mouse Model of Adenine-Induced Renal Injury Through Inhibiting TGF-beta1 Signaling Pathways. Frontiers in Cell and Developmental Biology, 9, 603802. [More Information]
Huang, C., Bian, J., Cao, Q., Chen, X., Pollock, C. (2021). The mitochondrial kinase pink1 in diabetic kidney disease. International Journal of Molecular Sciences, 22(4), 1-14. [More Information]

show 1 more

2020

Shi, Y., Huang, C., Yi, H., Cao, Q., Zhao, Y., Chen, J., Chen, X., Pollock, C. (2020). RIPK3 blockade attenuates kidney fibrosis in a folic acid model of renal injury. The FASEB Journal, 34(8), 10286-10298. [More Information]
Shi, Y., Huang, C., Zhao, Y., Cao, Q., Yi, H., Chen, X., Pollock, C. (2020). RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy. Scientific Reports, 10(1), 10458. [More Information]
Shi, Y., Chen, X., Huang, C., Pollock, C. (2020). RIPK3: A New Player in Renal Fibrosis. Frontiers in Cell and Developmental Biology, 8, 502. [More Information]

2019

Cao, Q., Chen, X., Huang, C., Pollock, C. (2019). MicroRNA as novel biomarkers and therapeutic targets in diabetic kidney disease: An update. FASEB BioAdvances, 1(6), 375-388. [More Information]

2018

Yi, H., Huang, C., Shi, Y., Cao, Q., Zhao, Y., Zhang, L., Chen, J., Pollock, C., Chen, X. (2018). Metformin attenuates folic-acid induced renal fibrosis in mice. Journal of Cellular Physiology, 233(9), 7045-7054. [More Information]
Huang, C., Zhang, L., Shi, Y., Yi, H., Zhao, Y., Chen, J., Pollock, C., Chen, X. (2018). The KCa3.1 blocker TRAM34 reverses renal damage in a mouse model of established diabetic nephropathy. PloS One, 13(2), 1-15. [More Information]

2016

Huang, C., Lin, Z., Cheng, D., Braet, F., Pollock, C., Chen, X. (2016). KCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys via PI3k/Akt/mTOR signaling pathways. Scientific Reports, 6, 1-12. [More Information]
Peeters, M., Huang, C., Vonk, L., Lu, Z., Bank, R., Helder, M., Doulabi, B. (2016). Optimisation of high-quality total ribonucleic acid isolation from cartilaginous tissues for real-time polymerase chain reaction analysis. Bone & Joint Research, 5(11), 560-568. [More Information]
Huang, C., Zhang, Y., Kelly, D., Tan, C., Gill, A., Cheng, D., Braet, F., Park, J., Sue, C., Pollock, C., Chen, X. (2016). Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway. Scientific Reports, 6, 1-13. [More Information]

2015

Huang, C., Pollock, C., Chen, X. (2015). KCa3.1: a new player in progressive kidney disease. Current Opinion In Nephrology And Hypertension, 24(1), 61-66. [More Information]

2014

Huang, C., Pollock, C., Chen, X. (2014). High Glucose Induces CCL20 in Proximal Tubular Cells via Activation of the KCa3.1 Channel. PloS One, 9(4), 1-8. [More Information]
Huang, C., Day, M., Poronnik, P., Pollock, C., Chen, X. (2014). Inhibition of KCa3.1 suppresses TGF-Beta1 induced MCP-1 expression in human proximal tubular cells through Smad3, p38 and ERK1/2 signaling pathways. International Journal of Biochemistry and Cell Biology, 47(1), 1-10. [More Information]
Gangadharan Komala, M., Gross, S., Mudaliar, H., Huang, C., Pegg, K., Mather, A., Shen, S., Pollock, C., Panchapakesan, U. (2014). Inhibition of Kidney Proximal Tubular Glucose Reabsorption Does Not Prevent against Diabetic Nephropathy in Type 1 Diabetic eNOS Knockout Mice. PloS One, 9(11), 1-12. [More Information]
Huang, C., Shen, S., Ma, Q., Gill, A., Pollock, C., Chen, X. (2014). KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis. Nephrology Dialysis Transplantation, 29(2), 313-324. [More Information]
Huang, C., Pollock, C., Chen, X. (2014). Role of the potassium channel KCa3.1 in diabetic nephropathy. Clinical Science, 127(7), 423-433. [More Information]
Huang, C., Lin, M., Cheng, D., Braet, F., Pollock, C., Chen, X. (2014). Thioredoxin-interacting protein mediates dysfunction of tubular autophagy in diabetic kidneys through inhibiting autophagic flux. Laboratory Investigation, 94(3), 309-320. [More Information]

show 3 more

2013

Huang, C., Shen, S., Ma, Q., Chen, J., Gill, A., Pollock, C., Chen, X. (2013). Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-Î²1/Smad Pathway in Diabetic Mice. Diabetes, 62(8), 2923-2934. [More Information]

Selected Grants

2022

Promoting the positive side of kidney fibroblasts to prevent and cure diabetic kidney disease, Chen X, Pollock C, Huang C, Juvenile Diabetes Research Foundation International (JDRF)/Innovative Grant (INO)

2019

PTEN-induced putative kinase 1 in renal fibrosis, Huang C, Faculty of Medicine and Health/Ignition Seed Fund Grant

2018

A novel therapeutic target for diabetic nephropathy, Huang C, DVC Research/Laffan Fellowships
A novel therapeutic target for diabetic nephropathy, Huang C, Chen X, Pollock C, Diabetes Australia Research Trust (DART)/Diabetes Research Grant Program

2017

A novel and unique protein i-body for the treatment of chronic kidney disease through targeting CXCR4, Pollock C, Foley M, Chen X, Huang C, National Health and Medical Research Council (NHMRC)/Project Grants

2015

Targeting microRNA-200b in diabetic nephropathy using two novel delivery systems, Huang C, National Health and Medical Research Council (NHMRC)/Early Career Fellowships

2014

Thioredoxin interacting protein (Txnip): A novel regulator of tubular autophagy in diabetic nephropathy, Huang C, University of Sydney/Early Career Researcher

Page not found