Professor David Burke
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Professor David Burke

AC, MB,BS (Syd), MD (UNSW), DSc (UNSW), FRACP, FAA, FTSE
Professor Emeritus
Central Clinical School
Phone
+61 2 9114 4250
Professor David Burke

clinical neurophysiology; motor control; peripheral nerve function

Neurosciences and Mental Health

Publications

Books

  • Pierrot-Deseilligny, E., Burke, D. (2012). The Circuitry of the Human Spinal Cord: Spinal and Corticospinal Mechanisms of Movement. Cambridge: Cambridge University Press. [More Information]
  • Pierrot-Deseilligny, E., Burke, D. (2005). The Circuitry of the Human Spinal Cord: Its Role in Motor Control and Movement Disorders. Cambridge: Cambridge University Press.

Book Chapters

  • Burke, D. (2017). Motor control: spinal and cortical mechanisms. In Kerry R. Mills (Eds.), Oxford Textbook of Clinical Neurophysiology, (pp. 19-30). Oxford: Oxford University Press. [More Information]
  • Burke, D., Howells, J. (2017). The motor unit. In Kerry R. Mills (Eds.), Oxford Textbook of Clinical Neurophysiology, (pp. 9-17). Oxford: Oxford University Press. [More Information]
  • Burke, D. (2014). Fusimotor System. Reference Module in Biomedical Sciences, (pp. 1-7). United States: Elsevier.

Journals

  • Ng, K., Kumar, K., Brew, B., Burke, D. (2024). Hypomagnesaemia, an independent risk factor for the development of post‐transplant diabetes mellitus in liver and renal transplant recipients? A systematic review. Journal of Human Nutrition and Dietetics, 37(6), 1407-1419. [More Information]
  • Wang, C., Bharathy, G., Prasad, M., Welgampola, M., Young, A., Raj, C., Bradshaw, A., Nham, B., Rosengren, S., Calic, Z., Burke, D., Halmagyi, G. (2024). Machine learning models help differentiate between causes of recurrent spontaneous vertigo. Journal of Neurology, 271(6), 3426-3438. [More Information]
  • Burke, D. (2022). Conduction studies on the sural nerve. Clinical Neurophysiology Practice, 7, 23-24. [More Information]

Conferences

  • Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2006). The Catch-Like property of human thenar muscles studied during brief trains of discharges. XIth International Congress on Neuromuscular Diseases, United Kingdom: Elsevier.

2024

  • Ng, K., Kumar, K., Brew, B., Burke, D. (2024). Hypomagnesaemia, an independent risk factor for the development of post‐transplant diabetes mellitus in liver and renal transplant recipients? A systematic review. Journal of Human Nutrition and Dietetics, 37(6), 1407-1419. [More Information]
  • Wang, C., Bharathy, G., Prasad, M., Welgampola, M., Young, A., Raj, C., Bradshaw, A., Nham, B., Rosengren, S., Calic, Z., Burke, D., Halmagyi, G. (2024). Machine learning models help differentiate between causes of recurrent spontaneous vertigo. Journal of Neurology, 271(6), 3426-3438. [More Information]

2022

  • Burke, D. (2022). Conduction studies on the sural nerve. Clinical Neurophysiology Practice, 7, 23-24. [More Information]

2021

  • Rothwell, J., Antal, A., Burke, D., Carlsen, A., Georgiev, D., Jahanshahi, M., Sternad, D., Valls-Sole, J., Ziemann, U. (2021). Central nervous system physiology. Clinical Neurophysiology, 132(12), 3043-3083. [More Information]
  • Dharmadasa, T., Howells, J., Matamala, J., Simon, N., Burke, D., Vucic, S., Kiernan, M. (2021). Cortical inexcitability defines an adverse clinical profile in amyotrophic lateral sclerosis. European Journal of Neurology, 28(1), 90-97. [More Information]
  • Burke, D. (2021). Crosstalk opposing view: Independent fusimotor control of muscle spindles in humans: there is little to gain. Journal of Physiology, 599(10), 2505-2508. [More Information]

2020

  • Shefner, J., Al-Chalabi, A., Baker, M., Cui, L., de Carvalho, M., Eisen, A., Großkreutz, J., Hardiman, O., Henderson, R., Matamala, J., Simon, N., Vucic, S., Burke, D., Kiernan, M., et al (2020). A proposal for new diagnostic criteria for ALS. Clinical Neurophysiology, 131(8), 1975-1978. [More Information]
  • Cheung, E., Parratt, J., Frith, J., Burke, D., Ng, K. (2020). Altered peripheral nerve excitability depends on severity of multiple sclerosis. Clinical Neurophysiology, 131(2), 589-591. [More Information]
  • Kiernan, M., Shefner, J., Kaji, R., Burke, D. (2020). Amyotrophic lateral sclerosis: A new diagnostic paradigm. Journal of Neurology, Neurosurgery and Psychiatry, 91(9), 903-904. [More Information]

2019

  • Lehmann, H., Burke, D., Kuwabara, S. (2019). Chronic inflammatory demyelinating polyneuropathy: update on diagnosis, immunopathogenesis and treatment. Journal of Neurology, Neurosurgery and Psychiatry, 90(9), 981-987. [More Information]
  • Burke, D. (2019). Hyperreflexia as an upper motor neuron sign in amyotrophic lateral sclerosis. Clinical Neurophysiology, 130(8), 1405-1406. [More Information]
  • Czesnik, D., Howells, J., Bartl, M., Veiz, E., Ketzler, R., Kemmet, O., Walters, A., Trenkwalder, C., Burke, D., Paulus, W. (2019). Ih contributes to increased motoneuron excitability in restless legs syndrome. Journal of Physiology, 597(2), 599-609. [More Information]

2018

  • Makker, P., Matamala, J., Park, S., Lees, J., Kiernan, M., Burke, D., Moalem-Taylor, G., Howells, J. (2018). A unified model of the excitability of mouse sensory and motor axons. Journal of the Peripheral Nervous System, 23(3), 159-173. [More Information]
  • Matamala, J., Howells, J., Dharmadasa, T., Huynh, W., Park, S., Burke, D., Kiernan, M. (2018). Excitability of sensory axons in amyotrophic lateral sclerosis. Clinical Neurophysiology, 129(7), 1472-1478. [More Information]
  • Tomlinson, S., Howells, J., Burke, D. (2018). In vivo assessment of neurological channelopathies: Application of peripheral nerve excitability studies. Neuropharmacology, 132, 98-107. [More Information]

2017

  • Burke, D. (2017). Clinical practice highlights in Clinical Neurophysiology in 2015 (July-December). Clinical Neurophysiology Practice, 2, 44-47. [More Information]
  • Burke, D. (2017). Motor control: spinal and cortical mechanisms. In Kerry R. Mills (Eds.), Oxford Textbook of Clinical Neurophysiology, (pp. 19-30). Oxford: Oxford University Press. [More Information]
  • van den Bos, M., Geevasinga, N., Menon, P., Burke, D., Kiernan, M., Vucic, S. (2017). Physiological processes influencing motor evoked potential duration with voluntary contraction. Journal of Neurophysiology, 117(3), 1156-1162. [More Information]

2016

  • Howells, J., Bostock, H., Burke, D. (2016). Accommodation to hyperpolarization of human axons assessed in the frequency domain. Journal of Neurophysiology, 116(2), 322-335. [More Information]
  • Burke, D. (2016). Clinical practice highlights in Clinical Neurophysiology in 2015 (April-June). Clinical Neurophysiology Practice, 1, 50-53. [More Information]
  • Burke, D. (2016). Clinical practice highlights in Clinical Neurophysiology in 2015 (January - March). Clinical Neurophysiology Practice, 1, 46-49. [More Information]

2015

  • Hafner, J., Ghaoui, R., Coyle, L., Burke, D., Ng, K. (2015). Axonal excitability in primary amyloidotic neuropathy. Muscle and Nerve, 51(3), 443-445. [More Information]
  • Burke, D. (2015). Clinical Neurophysiology in an era of change. Clinical Neurophysiology, 1269 (12), 2247-2248. [More Information]
  • Simon, N., Lee, M., Bae, J., Mioshi, E., Lin, C., Pfluger, C., Henderson, R., Vucic, S., Swash, M., Burke, D., Kiernan, M. (2015). Dissociated lower limb muscle involvement in amyotrophic lateral sclerosis. Journal of Neurology, 262(6), 1424-1432. [More Information]

2014

  • Liang, C., Howells, J., Kennerson, M., Nicholson, G., Burke, D., Ng, K. (2014). Axonal excitability in X-linked dominant Charcot Marie Tooth disease. Clinical Neurophysiology, 125(6), 1261-1269. [More Information]
  • Burke, D. (2014). Fusimotor System. Reference Module in Biomedical Sciences, (pp. 1-7). United States: Elsevier.
  • Burke, D. (2014). Inability of F waves to control for changes in the excitability of the motoneurone pool in motor control studies. Clinical Neurophysiology, 125(2), 221-222. [More Information]

2013

  • Ng, K., Kumar, K., Sue, C., Burke, D. (2013). Axonal excitability during ischemia in MELAS. Muscle and Nerve, 47(5), 762-765. [More Information]
  • Tomlinson, S., Rajakulendran, S., Tan, S., Graves, T., Bamiou, D., Labrum, R., Burke, D., Sue, C., Giunti, P., Schorge, S., et al (2013). Clinical, genetic, neurophysiological and functional study of new mutations in episodic ataxia type 1. Journal of Neurology, Neurosurgery and Psychiatry, 84(10), 1107-1112. [More Information]
  • Ng, K., Howells, J., Pollard, J., Burke, D. (2013). Different mechanisms underlying changes in excitability of peripheral nerve sensory and motor axons in multiple sclerosis. Muscle and Nerve, 47(1), 53-60. [More Information]

2012

  • Jankelowitz, S., Burke, D. (2012). Do the motor manifestations of parkinson disease alter motor axon excitability? Muscle and Nerve, 45(1), 43-47. [More Information]
  • Giboin, L., Lackmy-Vallée, A., Burke, D., Marchand-Pauvert, V. (2012). Enhanced propriospinal excitation from hand muscles to wrist flexors during reach-to-grasp in humans. Journal of Neurophysiology, 107(2), 532-543. [More Information]
  • Tomlinson, S., Bostock, H., Grinton, B., Hanna, M., Kullmann, D., Kiernan, M., Scheffer, I., Berkovic, S., Burke, D. (2012). In vivo loss of slow potassium channel activity in individuals with benign familial neonatal epilepsy in remission. Brain, 135, 3144-3152. [More Information]

2011

  • Park, S., Lin, C., Burke, D., Kiernan, M. (2011). Activity-dependent conduction failure: molecular insights. Journal of the Peripheral Nervous System, 16(3), 159-168. [More Information]
  • Kumar, K., Liang, C., Needham, M., Burke, D., Sue, C., Ng, K. (2011). Axonal hyperpolarization in inclusion-body myopathy, paget disease of the bone, and frontotemporal dementia (IBMPFD). Muscle and Nerve, 44(2), 191-196. [More Information]
  • Barnett, M., Barnett, Y., Burke, D., Willison, H. (2011). Spinal nerve root hypertrophy in chronic ataxic neuropathy with antiglycolipid IgM antibodies. Journal of Neurology, Neurosurgery and Psychiatry, 82(1), 97. [More Information]

2010

  • Burke, D., Pierrot-Deseilligny, E. (2010). Caveats when studying motor cortex excitability and the cortical control of movement using transcranial magnetic stimulation. Clinical Neurophysiology, 121(2), 121-123. [More Information]
  • Vucic, S., Burke, D., Kiernan, M. (2010). Fatigue in Multiple Sclerosis: Mechanisms and Management. Clinical Neurophysiology, 121(6), 809-817. [More Information]
  • Tomlinson, S., Tan, V., Kullmann, D., Griggs, R., Burke, D., Hanna, M., Bostock, H. (2010). Nerve excitability studies characterize KV1.1 fast potassium channel dysfunction in patients with episodic ataxia type 1. Brain, 133, 1-11. [More Information]

2009

  • Jankelowitz, S., Nikpour (Mohamed), A., Burke, D. (2009). Axonal effects of camphor poisoning. Journal of Clinical Neuroscience, 16(12), 1639-1641. [More Information]
  • Jankelowitz, S., Burke, D. (2009). Axonal excitability in the forearm: Normal data and differences along the median nerve. Clinical Neurophysiology, 120(1), 167-173. [More Information]
  • Tomlinson, S., Hanna, M., Kullmann, D., Tan, V., Burke, D. (2009). Clinical neurophysiology of the episodic ataxias: insights into ion channel dysfunction in vivo. Clinical Neurophysiology, 120(10), 1768-1776. [More Information]

2008

  • Uysal, H., Larsson, L., Efendi, H., Burke, D., Ertekin, C. (2008). Medium-latency reflex response of soleus elicited by peroneal nerve stimulation. Experimental Brain Research, 193(2), 275-286. [More Information]
  • McNulty, P., Jankelowitz, S., Wiendels, T., Burke, D. (2008). Post-activation depression of the soleus H reflex measured using threshold tracking. Journal of Neurophysiology, 100(6), 3275-3284. [More Information]
  • Burke, D. (2008). Recording MEPs to transcranial electrical stimulation and SEPs to peripheral nerve stimulation simultaneously from the spinal cord. In Marc R Nuwer (Eds.), Handbook of Clinical Neurophysiology: Intraoperative Monitoring of Neural Function, 8, (pp. 252-259). Netherlands: Elsevier. [More Information]

2007

  • Jankelowitz, S., McNulty, P., Burke, D. (2007). Changes in measures of motor axon excitability with age. Clinical Neurophysiology, 118(6), 1397-1404. [More Information]
  • Vucic, S., Burke, D., Kiernan, M. (2007). Diagnosis of motor neurone disease. In Kiernan M (Eds.), The Motor Neurone Disease Handbook, (pp. 89-104). Strawberry Hills, Australia: Australasian Med Publ Co Ltd.
  • Burke, D., Howells, J., Trevillion, L., Kiernan, M., Bostock, H. (2007). Inflections in threshold electrotonus to depolarizing currents in sensory axons. Muscle and Nerve, 36(6), 849-852. [More Information]

2006

  • Burke, D., Lin, C., Kiernan, M., Bostock, H. (2006). Assessment of nerve excitability properties in peripheral nerve disease. In Kimura J (Eds.), Handbook of Clinical Neurophysiology, (pp. 381-403). Amsterdam: Elsevier. [More Information]
  • Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2006). Augmentation of the contraction force of human thenar muscles by and during brief discharge trains. Muscle and Nerve, 33(3), 384-392. [More Information]
  • Burke, D., Kiernan, M. (2006). Developments in the assessment of peripheral nerve function. In Kimura J (Eds.), Handbook of Clinical Neurophysiology, (pp. 927-943). Amsterdam: Elsevier. [More Information]

2005

  • Kiernan, M., Isbister, G., Lin, C., Burke, D., Bostock, H. (2005). Acute tetrodotoxin-induced neurotoxicity after ingestion of puffer fish. Annals of Neurology, 57(3), 339-48. [More Information]
  • Bostock, H., Lin, C., Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2005). After-effects of near-threshold stimulation in single human motor axons. Journal of Physiology, 564(3), 931-940. [More Information]
  • Burke, D. (2005). Axonal excitability and intermittent conduction block in demyelinated axons. Turkish Journal of Neurology, 11, 457-465.

2004

  • Trevillion, L., Howells, J., Jankelowitz, S., Burke, D. (2004). Axonal Excitability Measured By Tracking Twitch Contraction Force. Muscle and Nerve, 30(4), 437-443. [More Information]
  • Burke, D., Cappelen-Smith, C., Kuwabara, S. (2004). Conduction Block In Demyelinated Axons Precipitated By Normally Innocuous Physiological Processes. Advances in Clinical Neurophysiology (supplement to clincal neurophysiology), 57(1), 191-194.
  • Krishnan, A., Pamphlett, R., Burke, D., Wills, E., Kiernan, M. (2004). Cytoplasmic Body Myopathy Masquerading As Motor Neuron Disease. Muscle and Nerve, 30(5), 667-672. [More Information]

2003

  • Cappelen-Smith, C., Lin, C., Burke, D. (2003). Activity-dependent hyperpolarization and impulse conduction in motor axons in patients with carpal tunnel syndrome. Brain, 126(4), 1001-1008. [More Information]
  • Burke, D., Gandevia, S., Macefield, V. (2003). Microneurography and motor disorders. In Hallett (Eds.), Movement Disorders: handbook of Clinical Neurophysiology: Volume 1, (pp. 153-162). Amsterdam: Elsevier.
  • Espiritu, M., Lin, C., Burke, D. (2003). Motoneuron excitability and the F wave. Muscle and Nerve, 27(6), 720-727. [More Information]

2002

  • Cappelen-Smith, C., Kuwabara, S., Lin, C., Burke, D. (2002). Abnormalities of axonal excitability are not generalized in early multi focal motor neuropathy. Muscle and Nerve, 26(6), 769-776. [More Information]
  • Kuwabara, S., Kanai, K., Sung, J., Ogawara, K., Hattori, T., Burke, D., Bostock, H. (2002). Axonal hyperpolarization associated with acute hypokalemia: multiple excitability measurements as indicators of the membrane potential of human axons. Muscle and Nerve, 26(2), 283-287. [More Information]
  • Cappelen-Smith, C., Lin, C., Kuwabara, S., Burke, D. (2002). Conduction block during and after ischaemia in chronic inflammatory demyelinating polyneuropathy. Brain, 125(8), 1850-1858. [More Information]

2001

  • Burke, D. (2001). Clinical relevance of the putative C3-C4 propriospinal system in humans. Muscle and Nerve, 24(11), 1437-1439.
  • Nicolas, G., Marchand-Pauvert, V., Burke, D., Pierrot-Deseilligny, E. (2001). Corticospinal excitation of presumed cervical propriospinal neurones and its reversal to inhibition in humans. Journal of Physiology, 533, 903-919.
  • Kuwabara, S., Cappelen-Smith, C., Lin, C., Mogyoros, I., Burke, D. (2001). Differences in accommodative properties of median and peroneal motor axons. Journal of Neurology, Neurosurgery and Psychiatry, 70, 372-376. [More Information]

Selected Grants

2012

  • Electrophysiological biomarkers of spinal neural activity in amyotrophic lateral sclerosis, Marchand-Pauvert V, Benali H, Pradat P, Kiernan M, Burke D, AFM Telethon/Research Support

2010

  • The final common channel: measurement for nerve excitability in epilepsy, Tomlinson S, Burke D, Kiernan M, National Health and Medical Research Council (NHMRC)/Project Grants
  • Excitability in human nerves, Burke D, DVC Research/Bridging Support Grant
  • Refurbishment and equipment for the Blackburn Building, Burke D, Perpetual Trustees Charitable Trusts/Research Support
  • Nerve excitability in genetic neurological ion channel disorders, Tomlinson S, Burke D, Sydney Foundation for Medical Research/Research Support