Professor Gemma Figtree
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Professor Gemma Figtree

Professor
Medicine, Northern Clinical School
Kolling Institute of Medical Research
Phone
+61 2 9926 7111
Details
Professor Gemma Figtree

Gemma Figtree is a Professor in Medicine at the University of Sydney. She co-leads the Cardiovascular Theme for Sydney Health Partners, a NHMRC Advanced Health Research and Translation Centre and is the Chair of the University of Sydney’s multi-disciplinary Cardiovascular Initiative.

Gemma completed her DPhil at Oxford University in 2002 supported by a Rhodes Scholarship making fundamental discoveries regarding estrogen’s actions and factors regulating NO/redox balance in the cardiovascular system. She is committed to improving the care for heart attack patients- using her knowledge of molecular and cellular biology to develop methods of identifying those at highest risk of adverse outcome, and discovering novel therapies to prevent and treat events,inspired by her clinical work as an interventional cardiologist.She has dedicated herself throughout her career to unravelling key mechanisms underlying susceptibility and response to heart attack, with studies extending from the bench to large cohort studies and clinical trials.

Discoveries in Prof Figtree's Laboratory have been published in leading journals Circulation, JACC and European Heart Journal, with > 150 publications. She is a principal investigator on grants >$8 mill. Having recently completed a co-funded NHMRC CDF and Heart Foundation Future Leader Fellowship, she was awarded a NHMRC Excellence Award for Top Ranked Practitioner Fellow (Australia), commencing in 2018. In 2019 she received the prestigious NSW Ministerial Award for Cardiovascular Research Excellence.

Prof Figtree is committed to the advancement of her field and serves as a member of the Editorial Board of leading international cardiovascular journals, includingCirculation,andCardiovascular Research, as well as being a founding editorial board member forRedox Biology, and an Associate Editor forHeart, Lung and Circulation.

Professor Figtree is committed to the promotion and advocacy of cardiovascular research, working as President of the Australian Cardiovascular Alliance with a national team to secure $220 Million Federal funding for the Mission for Cardiovascular Health, as well as being a member of the NSW CVD Advisory Committee. She has been appointed by the Minister as the Chair of the MRFF Mission's (CV) Expert Advisory Panel.Her perspective and leadership are recognised by her membership of the Scientific Board of Cardiac Society of Australia and New Zealand (responsible for International Relations), and her appointment to the Expert Advisory Panel for NHMRC Structural Review of Grants Program (2016-17), and as well as the Clinical Committee of the Heart Foundation. She is a graduate of the Australian Institute of Company Directors and serves/has served as a non-executive Director on multiple community Boards.She is deeply engaged in mentorship of early and mid-career researchers from a diverse range of research and personal backgrounds.

The breadth of Dr Figtree's research program spans from discovery of fundamental mechanisms and drug targets to precision medicine, clinical trials and implementation. The syndergy that this program of work has with her clinical job as an interventional cardiologist enables her to lead unique approaches to tackling cardiovascular disease. She is passionate about bringing together the future leaders of cardiovascular research from a diverse range of backgrounds to tackle the clinical problem.

Specific clinical questions that are the focus of the Figtree team's work include:

1. Mechanisms of coronary atherosclerosis in patients with no standard modifiable risk factors;

2. New blood biomarkers to detect early atherosclerosis and predict risk of heart attack;

3. Novel drug targets that tackle inflammation and oxidative stress in the heart and blood vessel;

4. Integrating advanced cardiovascular imaging, molecular markers and clinical data to predict risk;

5. Clinical trials

Clinical and interventional cardiology

Advanced cardiovascular imaging

Molecular and redox biology

Translational strategies

We have PhD and Master's opportunities for energetic and creative research students:

1. Mechanisms of coronary atherosclerosis in patients with no standard modifiable risk factors;

2. New blood biomarkers to detect early atherosclerosis and predict risk of heart attack;

3. Novel drug targets that tackle inflammation and oxidative stress in the heart and blood vessel;

4. Integrating advanced cardiovascular imaging, molecular markers and clinical data to predict risk;

5. Clinical trials: testing new therapies, and digital applications in coronary artery disease and peripheral arterial disease.

Australian Cardiovascular Alliance

Cardiac Society of Australia and New Zealand

University of Sydney Cardiovascular Initiative

American Heart Association

Royal Australian College of Physicians

Australian Institute of Company Directors

University of Sydney Faculty of Medicine and Health Award for Excellence- Outstanding Research Leadership- 2019

NSW Ministerial Award for Cardiovascular Research Excellence, 2019

NHMRC Excellence Award for Top Ranked Practitioner Fellow, 2018.

NHMRC Practitioner Fellowship, 2018-23

NSW Women of the Year Awards: Local Woman of the Year, Northern Sydney, 2017.

Barbara Ell Invited Guest Lecture, Victor Chang Institute of Cardiovascular Research, October, 2017.

Ray Knight Award for Research Mentorship, Cardiothoracic and Vascular Health, Kolling Institute and Northern Sydney Local Health District, 2017.

Colin Johnston Invited Guest Lecturer. High Blood Pressure Research Council of Australia, 2015.

NHMRC Career Development Fellowship (Level 2), 2014-18.

National Heart Foundation, Future Leader Fellowship, 2014-18 (co-funded with NHMRC CDF as above)

Sylvia and Charles Viertel Charitable Foundation- Clinical Investigatorship, 2010-11

Chapman Fellowship, Sydney Medical School Foundation, 2009-13

Rhodes Scholarship 1999-2002

Obesity, Diabetes and Cardiovascular Disease, Healthy Ageing
Project titleResearch student
Exploring evidence based management for ST segment elevation myocardial infarction patients without traditional cardiovascular risk factorsSuzanne AVIS
The identification of a novel blood based biosignature to detect early coronary artery diseasePich CHHAY
Topical therapeutics in peripheral vascular disease.Cameron EVANS
Utilising Patient Endothelial Colony Forming Cells as a Model for Investigating Redox signatures and Drug Targets for Coronary Artery DiseaseEugene LEE
State-of-the-art cardiac diagnostic techniques to improve diagnosis and management of heart diseaseManoj RAJAMOHAN
Coronary microvascular dysfunction and risk factorsSascha Swaraj SWARAJ

Publications

Books

  • Figtree, G. (2009). Genetic Variants in Estrogen Signaling Pathways. Germany: VDM Verlag.

Book Chapters

  • Vernon, S., O'Sullivan, J., Figtree, G. (2019). Metabolic signatures of redox-dependent cardiovascular diseases. In Sajal Chakraborti, Naranjan S Dhalla, Nirmal K Ganguly, Madhu Dikshit (Eds.), Oxidative Stress in Heart Diseases., (pp. 159-171). Singapore: Springer Nature Singapore. [More Information]

Journals

  • La Gerche, A., Dennis, M., Figtree, G., Kovacic, J., Maris, J., Nehme, Z., Parsons, S., Pflaumer, A., Puranik, R., Stub, D., et al (2024). A Call to Action to Improve Cardiac Arrest Outcomes: A Report From the National Summit for Cardiac Arrest. Heart, Lung, and Circulation. [More Information]
  • Kumar, A., Huangfu, G., Figtree, G., Dwivedi, G. (2024). Atherosclerosis as the Damocles' sword of human evolution: insights from nonhuman ape-like primates, ancient human remains, and isolated modern human populations. American Journal of Physiology - Heart and Circulatory Physiology, 326(3), H821-H831. [More Information]
  • Nurmohamed, N., Rodriguez, F., Sandhu, A., Nieman, K., Earls, J., Bax, J., Maron, D., Bhatt, D., van Rosendael, A., Danad, I., Figtree, G., et al (2024). Atherosclerosis evaluation and cardiovascular risk estimation using coronary computed tomography angiography. European Heart Journal, 45(20), 1783-1800. [More Information]

Conferences

  • Neubeck, A., Gallagher, R., Ingram, K., Celermajer, D., Schumacher, T., Ferry, K., Buckley, T., Redfern, J., Chow, C., Tofler, G., Figtree, G. (2016). MyHeartMate: Development of a Digital Game to Improve Secondary Prevention of Cardiovascular Disease. Abstracts for the 64th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Adelaide: Elsevier.
  • Figtree, G., Watkins, H., Robinson, B., Channon, K. (2006). Novel polymorphism in estrogen receptor alpha reverses negative transcriptional regulation and is associated with improved endothelial-dependent vasodilation. American Heart Association Annual Scientific Sessions 2005, United States: American Heart Association.

Patents

  • Figtree, G., Liu, C., Fry, N., Galougahi, K. (2017). Biomarkers of Oxidative Stress. Patent No. 9,638,699.

Report

  • Tam, C., Brieger, D., Gullick, J., Morris, J., Saavedra, A., Morris, R., Figtree, G., Vernon, S. (2020). Electronic Data on STEMI Patients (Stage 1).

2024

  • La Gerche, A., Dennis, M., Figtree, G., Kovacic, J., Maris, J., Nehme, Z., Parsons, S., Pflaumer, A., Puranik, R., Stub, D., et al (2024). A Call to Action to Improve Cardiac Arrest Outcomes: A Report From the National Summit for Cardiac Arrest. Heart, Lung, and Circulation. [More Information]
  • Kumar, A., Huangfu, G., Figtree, G., Dwivedi, G. (2024). Atherosclerosis as the Damocles' sword of human evolution: insights from nonhuman ape-like primates, ancient human remains, and isolated modern human populations. American Journal of Physiology - Heart and Circulatory Physiology, 326(3), H821-H831. [More Information]
  • Nurmohamed, N., Rodriguez, F., Sandhu, A., Nieman, K., Earls, J., Bax, J., Maron, D., Bhatt, D., van Rosendael, A., Danad, I., Figtree, G., et al (2024). Atherosclerosis evaluation and cardiovascular risk estimation using coronary computed tomography angiography. European Heart Journal, 45(20), 1783-1800. [More Information]

2023

  • Karimi Galougahi, K., Zhang, Y., Kienzle, V., Liu, C., Quek, L., Patel, S., Lau, E., Cordina, R., Figtree, G., Celermajer, D. (2023). β3 adrenergic agonism: A novel pathway which improves right ventricular-pulmonary arterial hemodynamics in pulmonary arterial hypertension. Physiological Reports, 11(1). [More Information]
  • Kavurma, M., Aitken, S., Boccanfuso, L., Cutmore, C., Passam, F., Patel, S., Hennessy, A., Loa, J., Figtree, G., Golledge, J. (2023). A hidden problem: peripheral artery disease in women. European Heart Journal - Quality of Care and Clinical Outcomes, 9(4), 342-350. [More Information]
  • Kong, G., Chin, Y., Lim, J., Ng, C., Kannan, S., Chong, B., Lin, C., Chan, K., Anand, V., Lee, E., Figtree, G., et al (2023). A two-decade population-based study on the effect of hypertension in the general population with obesity in the United States. Obesity, 31(3), 832-840. [More Information]

2022

  • Nour, D., Allahwala, U., Hansen, P., Figtree, G., Nelson, G., Ward, M., Bhindi, R. (2022). Angiographic predictors of coronary hemodynamics. Future Cardiology, 18(4), 299-308. [More Information]
  • Sharma, P., Liu Chung Ming, C., Wang, X., Bienvenu, L., Beck, D., Figtree, G., Boyle, A., Gentile, C. (2022). Biofabrication of advancedin vitro3D models to study ischaemic and doxorubicin-induced myocardial damage. Biofabrication, 14(2), 25003. [More Information]
  • Kott, K., Bishop, M., Yang, C., Plasto, T., Cheng, D., Kaplan, A., Cullen, L., Celermajer, D., Meikle, P., Vernon, S., Figtree, G. (2022). Biomarker Development in Cardiology: Reviewing the Past to Inform the Future. Cells, 11(3), 588. [More Information]

2021

  • Figtree, G., Broadfoot, K., Casadei, B., Califf, R., Crea, F., Drummond, G., Freedman, J., Guzik, T., Harrison, D., Hausenloy, D., et al (2021). A Call to Action for New Global Approaches to Cardiovascular Disease Drug Solutions. Circulation, 144(2), 159-169. [More Information]
  • Figtree, G., Broadfoot, K., Casadei, B., Califf, R., Crea, F., Drummond, G., Freedman, J., Guzik, T., Harrison, D., Hausenloy, D., et al (2021). A call to action for new global approaches to cardiovascular disease drug solutions. European Heart Journal, 42(15), 1464-1475. [More Information]
  • Kim, T., Tang, O., Vernon, S., Kott, K., Koay, Y., Park, J., James, D., Grieve, S., Speed, T., Yang, P., Figtree, G., John, O., Yang, J. (2021). A hierarchical approach to removal of unwanted variation for large-scale metabolomics data. Nature Communications, 12(1), 4992-1-4992-10. [More Information]

2020

  • Lembo, R., Gullick, J., Chow, C., Figtree, G., Kozor, R. (2020). A Study of Patient Satisfaction and Uncertainty in a Rapid Access Chest Pain Clinic. Heart, Lung, and Circulation, 29(8), e210-e216. [More Information]
  • Redfern, J., Figtree, G., Chow, C., Jennings, G., Briffa, T., Gallagher, R., Foreman, R. (2020). Cardiac Rehabilitation and Secondary Prevention Roundtable: Australian Implementation and Research Priorities. Heart, Lung, and Circulation, 29(3), 319-323. [More Information]
  • Allahwala, U., Weaver, J., Nelson, G., Nour, D., Ray, M., Ciofani, J., Ward, M., Figtree, G., Hansen, P., Bhindi, R. (2020). Effect of Recruitment of Acute Coronary Collaterals on In-Hospital Mortality and on Left Ventricular Function in Patients Presenting With ST Elevation Myocardial Infarction. American Journal of Cardiology, 125(10), 1455-1460. [More Information]

2019

  • Vijapurapu, R., Kozor, R., Hughes, D., Woolfson, P., Jovanovic, A., Deegan, P., Rusk, R., Figtree, G., Tchan, M., Whalley, D., et al (2019). A randomised controlled trial evaluating arrhythmia burden, risk of sudden cardiac death and stroke in patients with Fabry disease: the role of implantable loop recorders (RaILRoAD) compared with current standard practice. Trials, 20(1), 1-10. [More Information]
  • Callaghan, F., Bannon, P., Barin, E., Celermajer, D., Jeremy, R., Figtree, G., Grieve, S. (2019). Age-related changes of shape and flow dynamics in healthy adult aortas: A 4D flow MRI study. Journal of Magnetic Resonance Imaging, 49(1), 90-100. [More Information]
  • Kott, K., Vernon, S., Hansen, T., Yu, C., Bubb, K., Coffey, S., Sullivan, D., Yang, J., O'Sullivan, J., Chow, C., Patel, S., Chong, J., Celermajer, D., Kritharides, L., Grieve, S., Figtree, G. (2019). Biobanking for discovery of novel cardiovascular biomarkers using imaging-quantified disease burden: protocol for the longitudinal, prospective, BioHEART-CT cohort study. BMJ Open, 9(9), 1-9. [More Information]

2018

  • Lawley, C., Broadhouse, K., Callaghan, F., Winlaw, D., Figtree, G., Grieve, S. (2018). 4D flow magnetic resonance imaging: role in pediatric congenital heart disease. Asian Cardiovascular and Thoracic Annals, 26(1), 28-37. [More Information]
  • Bonnitcha, P., Grieve, S., Figtree, G. (2018). Clinical imaging of hypoxia: Current status and future directions. Free Radical Biology and Medicine, 126, 296-312. [More Information]
  • MacIsaac, A., Figtree, G. (2018). Why are women with ST-elevation myocardial infarction treated differently to men? Medical Journal of Australia, 209(3), 115-116. [More Information]

2017

  • Figtree, G., Liu, C., Fry, N., Galougahi, K. (2017). Biomarkers of Oxidative Stress. Patent No. 9,638,699.
  • Polonchuk, L., Chabria, M., Badi, L., Hofack, J., Figtree, G., Davies, M., Gentile, C. (2017). Cardiac spheroids as promising in vitro models to study the human heart microenvironment. Scientific Reports, 7(1), 1-12. [More Information]
  • Mawad, D., Figtree, G., Gentile, C. (2017). Current Technologies Based on the Knowledge of the Stem Cells Microenvironments. Advances in Experimental Medicine and Biology, 1041, 245-262. [More Information]

2016

  • Ngo, D., Roberts, C., Figtree, G. (2016). Association between interpregnancy interval and future risk of maternal cardiovascular disease-a population-based record linkage study. BJOG, 123(8), 1311-1318. [More Information]
  • Karimigalougahi, K., Liu, C., Garcia, A., Gentile, C., Fry, N., Hamilton, E., Hawkins, C., Figtree, G. (2016). Beta3 adrenergic stimulation restores nitric oxide/redox balance and enhances endothelial function in hyperglycemia. Journal of the American Heart Association, 5(2), 1-17. [More Information]
  • Kozor, R., Grieve, S., Tchan, M., Callaghan, F., Hamilton-Craig, C., Denaro, C., Moon, J., Figtree, G. (2016). Cardiac involvement in genotype-positive Fabry disease patients assessed by cardiovascular MR. Heart, 102(4), 298-302. [More Information]

2015

  • Kozor, R., Callaghan, F., Nelson, G., Figtree, G., Grieve, S. (2015). 4D Multi-VENC Cardiac MRI: Characterisation of a Functional Stenosis of the Ascending Aorta. Heart, Lung, and Circulation, 24(11), 1134-1135. [More Information]
  • Kozor, R., Callaghan, F., Tchan, M., Hamilton-Craig, C., Figtree, G., Grieve, S. (2015). A disproportionate contribution of papillary muscles and trabeculations to total left ventricular mass makes choice of cardiovascular magnetic resonance analysis technique critical in Fabry disease. Journal of Cardiovascular Magnetic Resonance, 17(1), 1-7. [More Information]
  • Karimigalougahi, K., Liu, C., Garcia, A., Fry, N., Hamilton, E., Figtree, G., Rasmussen, H. (2015). Beta3-Adrenoceptor activation relieves oxidative inhibition of the cardiac Na+-K+ pump in hyperglycemia induced by insulin receptor blockade. American Journal of Physiology: Cell Physiology, 309(5), C286-C295. [More Information]

2014

  • Grieve, S., Mazhar, J., Callaghan, F., Kok, C., Tandy, S., Bhindi, R., Figtree, G. (2014). Automated Quantification of Myocardial Salvage in a Rat Model of Ischemia-Reperfusion Injury Using 3D High-Resolution Magnetic Resonance Imaging (MRI). Journal of the American Heart Association, 3(4), 1-11. [More Information]
  • Murphy, J., Hansen, P., Bhindi, R., Figtree, G., Nelson, G., Ward, M. (2014). Cost Benefit for Assessment of Intermediate Coronary Stenosis with Fractional Flow Reserve in Public and Private Sectors in Australia. Heart, Lung, and Circulation, 23(9), 807-810. [More Information]
  • Kozor, R., Pollock, C., Gill, A., Bhindi, R., Figtree, G. (2014). Fabry disease deposition mimicking a cardiac tumour and precipitating heart block. European Heart Journal - Cardiovascular Imaging, 15(8), 869-869. [More Information]

2013

  • Ho, E., Karimigalougahi, K., Liu, C., Bhindi, R., Figtree, G. (2013). Biological markers of oxidative stress: Applications to cardiovascular research and practice. Redox Biology, 1(1), 483-491. [More Information]
  • Grieve, S., Lonborg, J., Mazhar, J., Tan, T., Ho, E., Liu, C., Lay, W., Gill, A., Kuchel, P., Bhindi, R., Figtree, G. (2013). Cardiac magnetic resonance imaging of rapid VCAM-1 up-regulation in myocardial ischemia-reperfusion injury. European Biophysics Journal, 42(1), 61-70. [More Information]
  • McMahon, R., Siow, W., Bhindi, R., Hoo, S., Figtree, G., Hansen, P., Nelson, G., Rasmussen, H., Ward, M. (2013). Left bundle branch block without concordant ST changes is rarely associated with acute coronary occlusion. International Journal of Cardiology, 167(4), 1339-1342. [More Information]

2012

  • Lay, W., Rayner, B., Sabaretnam, T., Figtree, G., Jackson, C., Hunyor, S., Bhindi, R. (2012). Activated protein C improves left ventricular remodelling after ischemia-reperfusion injury in rats. International Journal of Cardiology, 159(3), 246-248. [More Information]
  • Huang, A., Mathur, M., Figtree, G. (2012). Cardiac magnetic resonance characterization of an iatrogenic left ventricular apical pseudo- aneurysm. European journal of Echocardiography, 13(12), 1000-1000. [More Information]
  • Buchholz, S., Shakil, A., Figtree, G., Hansen, P., Bhindi, R. (2012). Diagnosis and management of patent foramen ovale. Postgraduate Medical Journal, 88(1038), 217-225. [More Information]

2011

  • Figtree, G., Lonborg, J., Grieve, S., Ward, M., Bhindi, R. (2011). Cardiac Magnetic Resonance Imaging for the Interventional Cardiologist. J A C C: Cardiovascular Interventions, 4(2), 137-148. [More Information]
  • Hamilton, E., Figtree, G., Rasmussen, H. (2011). Consideration of natriuretic peptide receptor C. Circulation Research, 108(4), e4-e5. [More Information]
  • Bibert, S., Liu, C., Figtree, G., Garcia, A., Hamilton, E., Marassi, F., Sweadner, K., Cornelius, F., Geering, K., Rasmussen, H. (2011). FXYD Proteins Reverse Inhibition of the Na+-K+ Pump Mediated by Glutathionylation of Its beta 1 Subunit. Journal of Biological Chemistry, 286(21), 18562-18572. [More Information]

2010

  • White, C., Liu, C., Garcia, A., Hamilton, E., Chia, K., Figtree, G., Rasmussen, H. (2010). Activation of cAMP-dependent signaling induces oxidative modification of the cardiac Na+-K+ pump and inhibits its activity. Journal of Biological Chemistry, 285(18), 13712-13720. [More Information]
  • Robaei, D., Grieve, S., Nelson, G., Figtree, G. (2010). Cocaine-induced epicardial coronary artery thrombosis resulting in extensive myocardial injury assessed by cardiac magnetic resonance imaging. European Heart Journal, 31(20), 2446. [More Information]
  • Buchholz, S., Grieve, S., Maher, R., Figtree, G. (2010). Cocaine-induced myocardial injury seen as multiple mid-wall foci of late enhancement by contrast-enhanced cardiac magnetic resonance imaging. European Heart Journal, 31(11), 1422. [More Information]

2009

  • White, C., Figtree, G., Liu, C., Garcia, A., Hamilton, E., Chia, K., Rasmussen, H. (2009). Angiotensin II inhibits the Na+-K+ pump via PKC-dependent activation of NADPH oxidase. American Journal of Physiology: Cell Physiology, 296(4), C693-C700. [More Information]
  • Figtree, G., Noonan, J., Bhindi, R., Collins, P. (2009). Estrogen Receptor Polymorphisms: Significance to Human Physiology, Disease and Therapy. Recent Patents on DNA and Gene Sequences, , 0. [More Information]
  • Figtree, G. (2009). Genetic Variants in Estrogen Signaling Pathways. Germany: VDM Verlag.

2008

  • Figtree, G., Grieve, S., Speller, B., Geiger, M., Robinson, B., Channon, K., Ragoussis, J., Collins, P., Watkins, H. (2008). A commonly occurring polymorphism upstream of the estrogen receptor alpha alters transcription and is associated with increased HDL. Atherosclerosis, 199(2), 354-361. [More Information]
  • William, M., Hamilton, E., Bundgaard, H., Garcia, A., Chia, K., Figtree, G., Rasmussen, H. (2008). Natriuretic peptides stimulate the cardiac sodium pump via NPR-C coupled NOS activation. American Journal of Physiology: Cell Physiology, 294(4), C1067-C1073. [More Information]
  • White, C., Hamilton, E., Garcia, A., Wang, D., Chia, K., Figtree, G., Rasmussen, H. (2008). Opposing effects of coupled and uncoupled NOS activity on the Na+-K+ pump in cardiac myocytes. American Journal of Physiology: Cell Physiology, 294, C572-C578. [More Information]

2007

  • Rasmussen, H., Figtree, G. (2007). "Don't flog the heart!" - development of specific drug therapies for heart failure. Critical Care and Resuscitation, 9(4), 364-369. [More Information]

2006

  • Goodstadt, L., Powell, T., Figtree, G. (2006). 17β-Estradiol Potentiates the Cardiac Cystic Fibrosis Transmembrane Conductance Regulator Chloride Current in Guinea-pig Ventricular Myocytes. The Journal of Physiological Sciences, 56(1), 29-37. [More Information]
  • Figtree, G., Kindmark, A., Lind, L., Grundberg, E., Speller, B., Robinson, B., Channon, K., Watkins, H. (2006). Novel estrogen receptor alpha promoter polymorphism increases ventricular hypertrophic response to hypertension. Journal of Steroid Biochemistry and Molecular Biology, 103(2), 110-118. [More Information]
  • Figtree, G., Watkins, H., Robinson, B., Channon, K. (2006). Novel polymorphism in estrogen receptor alpha reverses negative transcriptional regulation and is associated with improved endothelial-dependent vasodilation. American Heart Association Annual Scientific Sessions 2005, United States: American Heart Association.

2004

  • Figtree, G., Robinson, B. (2004). Estrogen Receptor Polymorphisms In Common Disease:Recent Developments. Current Opinion in Endocrinology, Diabetes and Obesity, 11(3), 141-146. [More Information]

2003

  • Figtree, G., McDonald, D., Watkins, H., Channon, K. (2003). Truncated Estrogen Receptor α 46-kDa Isoform in Human Endothelial Cells: Relationship to Acute Activation of Nitric Oxide Synthase. Circulation, 107(1), 120-126. [More Information]
  • Cooper, L., Clifton-Bligh, P., Nery, M., Figtree, G., Twigg, S., Hibbert, E., Robinson, B. (2003). Vitamin D supplementation and bone mineral density in early postmenopausal women. American Journal of Clinical Nutrition, 77(5), 1324-1329.

Selected Grants

2024

  • Using CHIP as a cost-effective tool for early detection of cardiovascular disease, Tang O, Figtree G, Heart Research Australia/Donation
  • POPSTEM: Patient-specific cardiac stem cell villages for personalised therapeutic design, Powell J, Figtree G, Department of Health and Aged Care (Federal - administered by NHMRC)/2023 MRFF Stem Cell Therapies Mission
  • Commercialising the results of heart research with the aim of reducing the incidence of heart attacks and carrying out the detailed business plan of the Recipient., Figtree G, DVC Research/CRFI-Irma Margaret Rosalie Downie - Bequest (Heart Research)

2023

  • Improving early diagnosis and treatment of CAD- above and beyond standard modifiable risk factors (SMuRFs), Figtree G, Xiang M, Yang J, Grieve S, Cordwell S, McGuire H, Vernon S, Office of Global Engagement/Ignition Grants
  • Rewarding Research 2024, Figtree G, Faculty of Medicine and Health/FMH Rewarding Research Success
  • CVD research program funding support, Figtree G, Faculty of Medicine and Health/Internal Research
  • Dissecting the susceptibility of humans to coronary artery disease (CAD), Tang O, McGuire H, Figtree G, Patrick E, Gray M, Heart Research Australia/Research Grant
  • Clinical and health economics implications of routine CTCA for emergency department assessment of Aboriginal and Torres Strait Islander people at risk of acute coronary syndrome, Cullen L, Figtree G, Parsonage W, Stephensen L, Mahoney R, Greenslade J, Department of Health and Aged Care (Federal - administered by NHMRC)/Cardiovascular Health Mission - 2022 Cardiovascular Health Grant

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