Associate Professor George Hruby
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Associate Professor George Hruby

Clinical Associate Professor
Medicine, Northern Clinical School
Dept. Radiation Oncology, Royal North Shore Hospital
Genesis Cancer Care, Sydney
Faculty of Medicine and Health
Phone
02 95158057
Fax
02 95158115

Radiation Oncology:GU cancers, GI cancers and Merkel Cell Carcinoma.

Publications

Book Chapters

  • Broadbent, A., Hruby, G. (2008). Brain secondaries. In N. Christakis and P. Glare (Eds.), Prognosis in Advanced Cancer, (pp. 285-294). Oxford: Oxford University Press.

Journals

  • Scharl, S., Kroeze, S., Guckenberger, M., Krafcsik, M., Hruby, G., Emmett, L., Schmidt-Hegemann, N., Trapp, C., Spohn, S., Henkenberens, C., et al (2024). European association of urology risk stratification predicts outcome in patients receiving PSMA-PET-planned salvage radiotherapy for biochemical recurrence following radical prostatectomy. Radiotherapy and Oncology, 194, 110215. [More Information]
  • Leow, B., Eade, T., Hruby, G., Lieng, H., Hsiao, E., Brown, C., Kneebone, A. (2024). Prognostic impact of prostate-specific membrane antigen positron emission tomography (PSMA PET) staging for clinically node-positive prostate cancer. Journal of Medical Imaging and Radiation Oncology. [More Information]
  • Schuler, T., Carroll, S., Hruby, G., Jayamanne, D., Kneebone, A., Lamoury, G., Morgia, M., Stevens, M., Brown, C., Gallego, B., Booth, J., Eade, T., Kipritidis, J., Back, M., Bergamin, S., et al (2024). Real-World Implementation of Simulation-Free Radiation Therapy (SFRT-1000): A Propensity Score-Matched Analysis of 1000 Consecutive Palliative Courses Delivered in Routine Care. International Journal of Radiation Oncology Biology Physics. [More Information]

2024

  • Scharl, S., Kroeze, S., Guckenberger, M., Krafcsik, M., Hruby, G., Emmett, L., Schmidt-Hegemann, N., Trapp, C., Spohn, S., Henkenberens, C., et al (2024). European association of urology risk stratification predicts outcome in patients receiving PSMA-PET-planned salvage radiotherapy for biochemical recurrence following radical prostatectomy. Radiotherapy and Oncology, 194, 110215. [More Information]
  • Leow, B., Eade, T., Hruby, G., Lieng, H., Hsiao, E., Brown, C., Kneebone, A. (2024). Prognostic impact of prostate-specific membrane antigen positron emission tomography (PSMA PET) staging for clinically node-positive prostate cancer. Journal of Medical Imaging and Radiation Oncology. [More Information]
  • Schuler, T., Carroll, S., Hruby, G., Jayamanne, D., Kneebone, A., Lamoury, G., Morgia, M., Stevens, M., Brown, C., Gallego, B., Booth, J., Eade, T., Kipritidis, J., Back, M., Bergamin, S., et al (2024). Real-World Implementation of Simulation-Free Radiation Therapy (SFRT-1000): A Propensity Score-Matched Analysis of 1000 Consecutive Palliative Courses Delivered in Routine Care. International Journal of Radiation Oncology Biology Physics. [More Information]

2023

  • Wong, J., Allwright, M., Hruby, G., Margaret Roberts, J., Carr, A., Jin, F., Gett, R., Meagher, A., Hillman, R. (2023). Anal cancer: a 20-year retrospective study from Australia. ANZ Journal of Surgery, 93(11), 2697-2705. [More Information]
  • Tse, B., Molloy, M., Bergamin, S., Steffen, P., Hruby, G., Pavlakis, N., Clarke, S., Evans, J., Engel, A., Kneebone, A. (2023). CD11c+ and IRF8+ cell densities in rectal cancer biopsies predict outcomes of neoadjuvant chemoradiotherapy. OncoImmunology, 12(1), 2238506. [More Information]
  • Cheng, Q., Poynten, I., Jin, F., Grulich, A., Ong, J., Hillman, R., Hruby, G., Howard, K., Newall, A., Boettiger, D. (2023). Cost-effectiveness of screening and treating anal pre-cancerous lesions among gay, bisexual and other men who have sex with men living with HIV. The Lancet Regional Health. Western Pacific, 32. [More Information]

2022

  • Horsley, P., Kneebone, A., Eade, T., Hruby, G. (2022). Don't throw the baby out with the bath water. The Prostate, 82(3), 397-398. [More Information]
  • Eade, T., Kneebone, A., Hruby, G., Booth, J., Hsiao, E., Le, A., Kwong, C., Atyeo, J., Brown, C., Hunter, J., et al (2022). Early Outcomes and Decision Regret Using PSMA/MRI-Guided Focal Boost for Prostate Cancer SBRT. Practical Radiation Oncology, 12(3), e201-e206. [More Information]
  • Roberts, M., Chatfield, M., Hruby, G., Nandurkar, R., Roach, P., Watts, J., Cusick, T., Kneebone, A., Eade, T., Ho, B., Stricker, P., et al (2022). Event-free survival after radical prostatectomy according to prostate-specific membrane antigen-positron emission tomography and European Association of Urology biochemical recurrence risk groups. BJU International, 130(S3), 32-39. [More Information]

2021

  • Chou, A., Seyed Ahadi, M., Arena, J., Sioson, L., Sheen, A., Fuchs, T., Pavlakis, N., Clarke, S., Kneebone, A., Hruby, G., et al (2021). A Critical Assessment of Postneoadjuvant Therapy Pancreatic Cancer Regression Grading Schemes with a Proposal for a Novel Approach. American Journal of Surgical Pathology, 45(3), 394-404. [More Information]
  • Toby, J., Eade, T., Hruby, G., Kneebone, A., Aherne, N., Brown, C., Guo, L., Hoffmann, M., Shakespeare, T. (2021). Assessing ISUP prostate cancer grade groups in patients treated with definitive dose escalated external beam radiation. Radiotherapy and Oncology, 162, 91-97. [More Information]
  • Wong, S., Roderick, S., Kejda, A., Atyeo, J., Grimberg, K., Porter, B., Booth, J., Hruby, G., Eade, T. (2021). Diagnostic Computed Tomography Enabled Planning for Palliative Radiation Therapy: Removing the Need for a Planning Computed Tomography Scan. Practical Radiation Oncology, 11(2), e146-e153. [More Information]

2020

  • Emmett, L., Tang, R., Nandurkar, R., Hruby, G., Roach, P., Watts, J., Cusick, T., Kneebone, A., Ho, B., Chan, L., Stricker, P., et al (2020). 3-Year Freedom from Progression After 68Ga-PSMA PET/CT-Triaged Management in Men with Biochemical Recurrence After Radical Prostatectomy: Results of a Prospective Multicenter Trial. Journal of Nuclear Medicine, 61(6), 866-872. [More Information]
  • Oar, A., Lee, M., Le, H., Hruby, G., Dalfsen, R., Pryor, D., Lee, D., Chu, J., Holloway, L., Briggs, A., Samra, J., Kneebone, A., et al (2020). Australasian Gastrointestinal Trials Group (AGITG) and Trans-Tasman Radiation Oncology Group (TROG) Guidelines for Pancreatic Stereotactic Body Radiation Therapy (SBRT). Practical Radiation Oncology, 10(3), e136-e146. [More Information]
  • Emmett, L., Hruby, G. (2020). Clinical impact of PET imaging in prostate cancer management. Current Opinion in Urology, 30(5), 649-653. [More Information]

2019

  • Collier, N., Kneebone, A., Hruby, G., McCloud, P., Booth, J., Eade, T. (2019). A simple algorithm to predict non-compliance with organ at risk dose-volume constraints when planning intensity modulated post-prostatectomy radiation treatment: 'Why we should put the CART before the horse'. Journal of Medical Imaging and Radiation Oncology, 63(4), 546-551. [More Information]
  • Hong, A., Fogarty, G., Dolven-Jacobsen, K., Burmeister, B., Lo, S., Haydu, L., Vardy, J., Nowak, A., Dhillon, H., Ahmed, T., Shivalingam, B., Long, G., Menzies, A., Hruby, G., Paton, E., Steel, V., Williams, N., Scolyer, R., Morton, R., Thompson, J., et al (2019). Adjuvant Whole-Brain Radiation Therapy Compared With Observation After Local Treatment of Melanoma Brain Metastases: A Multicenter, Randomized Phase III Trial. Journal of Clinical Oncology, 37(33), 3132-3141. [More Information]
  • Schuler, T., Kipritidis, J., Eade, T., Hruby, G., Kneebone, A., Mario, P., Grimberg, K., Richardson, K., Evill, S., Evans, B., et al (2019). Big Data Readiness in Radiation Oncology: An Efficient Approach for Relabeling Radiation Therapy Structures With Their TG-263 Standard Name in Real-World Data Sets. Advances in Radiation Oncology, 4(1), 191-200. [More Information]

2018

  • Hruby, G., Eade, T., Emmett, L., Ho, B., Hsiao, E., Schembri, G., Guo, L., Kwong, C., Hunter, J., Byrne, K., Kneebone, A. (2018). 68Ga-PSMA-PET/CT staging prior to definitive radiation treatment for prostate cancer. Asia-Pacific Journal of Clinical Oncology, 14(4), 343-346. [More Information]
  • Oh, B., Eade, T., Kneebone, A., Hruby, G., Lamoury, G., Pavlakis, N., Clarke, S., Zaslawski, C., Marr, I., Costa, D., Back, M. (2018). Acupuncture in Oncology: The Effectiveness of Acupuncture May Not Depend on Needle Retention Duration. Integrative Cancer Therapies, 17(2), 458-466. [More Information]
  • Van Gysen, K., Kneebone, A., Eade, T., Guminski, A., Hruby, G. (2018). Advanced Renal Cell Cancer and Low-Dose Palliative Radiation Treatment: A Case of a Substantial and Sustained Treatment Response. Case Reports in Oncology, 11(3), 756-762. [More Information]

2017

  • Choong, E., Hruby, G., Yang, J., Kwong, C., Patanjali, N. (2017). 78Gy with Fiducial Marker Image-Guided Radiotherapy in Prostate Cancer: Single Center Analysis of 301 Patients. Asia-Pacific Journal of Clinical Oncology, 13(5), e356-e363. [More Information]
  • Hruby, G., Eade, T., Kneebone, A., Emett, L., Guo, L., Ho, B., Hsiao, E., Schembri, G., Hunter, J., Kwong, C. (2017). Delineating biochemical failure with (68)Ga-PSMA-PET following definitive external beam radiation treatment for prostate cancer. Radiotherapy and Oncology, 122(1), 99-102. [More Information]
  • Bell, L., Eade, T., Kneebone, A., Hruby, G., Alfieri, F., Bromley, R., Grimberg, K., Barnes, M., Booth, J. (2017). Initial experience with intra-fraction motion monitoring using Calypso guided volumetric modulated arc therapy for definitive prostate cancer treatment. Journal of Medical Radiation Sciences, 64(1), 25-34. [More Information]

2016

  • van Leeuwen, P., Stricker, P., Hruby, G., Kneebone, A., Ting, F., Thompson, B., Nguyen, Q., Ho, B., Emmett, L. (2016). 68Ga-PSMA has high detection rate of prostate cancer recurrence outside the prostatic fossa in patients being considered for salvage radiation treatment. BJU International, 117(5), 732-739. [More Information]
  • Oh, B., Figtree, G., Costa, D., Eade, T., Hruby, G., Lim, S., Elfiky, A., Martine, N., Rosenthal, D., Clarke, S., Back, M. (2016). Oxidative stress in prostate cancer patients: A systematic review of case control studies. Prostate International, 4(3), 71-87. [More Information]
  • Whalley, D., Hruby, G., Alfieri, F., Kneebone, A., Eade, T. (2016). SpaceOAR Hydrogel in Dose-escalated Prostate Cancer Radiotherapy: Rectal Dosimetry and Late Toxicity. Clinical Oncology, 28(10), e148-e154. [More Information]

2015

  • Butow, P., Kelly, S., Thewes, B., Hruby, G., Sharpe, L., Beith, J. (2015). Attentional bias and metacognitions in cancer survivors with high fear of cancer recurrence. Psycho-Oncology, 24(4), 416-423. [More Information]
  • Honeyball, F., Murali-Ganesh, R., Hruby, G., Grimison, P. (2015). Compliance of males with stage 1 testicular germ cell tumours on an active surveillance protocol. Internal Medicine Journal, 45(10), 1081-1084. [More Information]
  • Fogarty, G., Hong, A., Dolven-Jacobson, K., Reisse, C., Burmeister, B., Haydu, L., Dhillon, H., Steel, V., Shivalingam, B., Drummond, K., Vardy, J., Hruby, G., Scolyer, R., Thompson, J., et al (2015). First interim analysis of a randomised trial of whole brain radiotherapy in melanoma brain metastases confirms high data quality. BMC Research Notes, 8, 1-6. [More Information]

2014

  • Suttie, C., Hruby, G., Horvath, L., Thompson, J. (2014). Cardiac metastasis in Merkel cell carcinoma. Journal of Clinical Oncology, 32(13), e52-e53. [More Information]
  • Thompson, S., Delaney, G., Gabriel, G., Izard, M., Hruby, G., Jagavkar, R., Bucci, J., Barton, M. (2014). Prostate brachytherapy in New South Wales: Patterns of care study and impact of caseload on treatment quality. Journal of Contemporary Brachytherapy, 6(4), 344-349. [More Information]
  • Elsner, K., Francis, K., Hruby, G., Roderick, S. (2014). Quality improvement process to assess tattoo alignment, set-up accuracy and isocentre reproducibility in pelvic radiotherapy patients. Journal of Medical Radiation Sciences, 61, 246-252. [More Information]

2013

  • Gzell, C., Kench, J., Stockler, M., Hruby, G. (2013). Biopsy-proven brain metastases from prostate cancer: a series of four cases with review of the literature. International Urology and Nephrology, 45(3), 735-742. [More Information]
  • Finnigan, R., Hruby, G., Wratten, C., Keller, J., Tripcony, L., Dickie, G., Rischin, D., Poulsen, M. (2013). The Impact of Preradiation Residual Disease Volume on Time to Locoregional Failure in Cutaneous Merkel Cell Carcinoma-A TROG Substudy. International Journal of Radiation Oncology Biology Physics, 86(1), 91-95. [More Information]
  • Hruby, G., Scolyer, R., Thompson, J. (2013). The important role of radiation treatment in the management of Merkel cell carcinoma. British Journal of Dermatology, 169(5), 975-982. [More Information]

2012

  • Martin, D., Hruby, G., Whitaker, M., Foo, K. (2012). Constrained-beam inverse planning for intensity-modulated radiation therapy of prostate cancer patients with bilateral hip prostheses. Journal of Medical Imaging and Radiation Oncology, 56(6), 703-707. [More Information]
  • Sundaresan, P., Hruby, G., Hamilton, A., Hong, A., Boyer, M., Chatfield, M., Thompson, J. (2012). Definitive Radiotherapy or Chemoradiotherapy in the Treatment of Merkel Cell Carcinoma. Clinical Oncology, 24(9), e131-e136. [More Information]
  • Whalley, D., Patanjali, N., Jackson, M., Lovett, A., Chatfield, M., Hruby, G. (2012). HDR brachytherapy combined with external beam radiation for localised prostate cancer: Early experience from the Sydney Cancer Centre. Journal of Medical Imaging and Radiation Oncology, 56(2), 220-226. [More Information]

2011

  • Suchowerska, N., Jackson, M., Lambert, J., Yin, Y., Hruby, G., McKenzie, D. (2011). Clinical Trials of a Urethral Dose Measurement System in Brachytherapy Using Scintillation Detectors. International Journal of Radiation: Oncology - Biology - Physics, 79(2), 609-615. [More Information]
  • Chen, J., Hruby, G., Stockler, M., Patanjali, N., Bucci, J., Perez, G., Loadsman, J., Sheehan, E. (2011). Patient-reported outcomes of prostate high-dose-rate brachytherapy boost comparing an outpatient and inpatient protocol: A two-center chronologic cohort study. Brachytherapy, 10(6), 454-460. [More Information]
  • Hruby, G., Chen, J., Bucci, J., Loadsman, J., Perry, P., Stockler, M. (2011). Patients' experiences of high-dose-rate brachytherapy boost for prostate cancer using an inpatient protocol. Brachytherapy, 10(5), 395-400. [More Information]

2009

  • Zajac, J., Solomon, M., Hruby, G., Frizelle, F. (2009). Review of 120 anal cancer patients. Colorectal Disease, 11, 909-14. [More Information]

2008

  • Doyle, C., Loadsman, J., Hruby, G. (2008). An audit of analgesia requirements for high-dose-rate prostate brachytherapy. Anaesthesia and Intensive Care, 36(5), 707-709. [More Information]
  • Broadbent, A., Hruby, G. (2008). Brain secondaries. In N. Christakis and P. Glare (Eds.), Prognosis in Advanced Cancer, (pp. 285-294). Oxford: Oxford University Press.
  • Chen, J., Hruby, G., Scolyer, R., Murali, R., Hong, A., FitzGerald, P., Pham, T., Quinn, M., Thompson, J. (2008). Desmoplastic neurotropic melanoma: a clinicopathologic analysis of 128 cases. Cancer, 113(10), 2770-2778. [More Information]

2007

  • Jabbour, J., Cumming, R., Scolyer, R., Hruby, G., Thompson, J., Lee, S. (2007). Merkel Cell Carcinoma: Assessing the Effect of Wide Local Excision, Lymph Node Dissection, and Radiotherapy on Recurrence and Survival in Early-Stage Disease-Results From a Review of 82 Consecutive Cases Diagnosed Between 1992 and 2004. Annals of Surgical Oncology, 14(6), 1943-1952. [More Information]
  • Harrison, J., Solomon, M., Young, J., Meagher, A., Hruby, G., Salkeld, G., Clarke, S. (2007). Surgical and oncology trials for rectal cancer: Who will participate? Surgery, 142(1), 94-101. [More Information]

2006

  • Butow, P., Solomon, M., Young, J., Whelan, T., Salkeld, G., Wilson, K., Harrison, J., Hruby, G., Mansour, O., Kennedy, N., Tattersall, M. (2006). Consumer impact of an interactive decision aid for rectal cancer patients offered adjuvant therapy. Colorectal Disease, 8(8), 676-682. [More Information]

2004

  • Broadbent, A., Hruby, G., Tin, M., Jackson, M., Firth, I. (2004). Survival Following Whole Brain Radiation Treatment For Cerebral Metastases: An Audit Of 474 Patients. Radiotherapy and Oncology, 71(3), 259-265. [More Information]

2002

  • Hruby, G., Choo, R., Jackson, M., Warde, P., Sandler, H. (2002). Management preferences following radical inguinal orchidectomy for Stage 1 testicular seminoma in Australasia. Journal of Medical Imaging and Radiation Oncology, 46(3), 280-284. [More Information]

Selected Grants

2007

  • Preop chemoradiotherapy&postop chemo with capeciabine&oxaliplatin vs capecitabine alone in locally a, Price T, Harvey J, Tebbutt N, Hruby G, Bydder S, Simes R, Zalcberg J, Cancer Australia/Priority Driven Collaborative Cancer Research Scheme