People_

Dr Hugh McCarthy

BSc, MBBS, MRCPCH, PhD, FRACP

Staff Specialist Paediatric Nephrology, Sydney Children's Hospital Network
Senior Lecturer, Paediatrics and Child Health, Children's Hospital at Westmead

Phone

2

Email

hugh.mccarthy@sydney.edu.au

Websites

Australasian Registry of Rare and Genetic Kidney DIsease

Resume

Curriculum vitae

Biographical details

I am a Clinical Academic and Paediatric Nephrologist based within the The Children's Hospital at Westmead Clinical School. My research focus is into the genomic determinants of kidney disease and the molecular basis of podocytopathies. I trained in the UK and completed my PhD at the University of Bristol, under the supervision of Professor Moin Saleem. In Australia, I am a founding member of the KIDGEN initiative - a national multidisciplinary collaborative studying the aetiology and management of genetic kidney disease. I co-designed the first diagnostic Australian Renal Gene Panel service, confering direct benefit to over 800 Australian renal patients from genomic advances in the field. In my clinical role, I developed and continue to run the NSW/ACT paediatric renal genetic clinical service. I work directly with patient advocacy groups in Australia to ensure consumer engagement. I supervise PhD, Honour and MD research project students within the Centre for Kidney Research, Westmead and am currently supervising projects including: Co-development of the Renal Genetic Clinical Service; Deciphering the aetiology of non-Mendelian nephrotic syndrome; novel gene discovery in renal disease. I am CIC on the MRFF funded OPEN study of prednisolone dosing in relapses of childhood steroid sensitive nephrotic syndrome and am the Clinical Lead for the Nacuity sponsered national Phase 2 trial in Cystinosis.

Research interests

Genomics of Renal Disease

Proteomics of Podocytopathies

Rare Disease Patient Registries

Teaching and supervision

Nephrology

General Paediatrics

Rare Disease

MD Program Year 3 Research Project Coordinator for the CHW Clinical School

Current projects

Associations

Australian and New Zealand Paediatric Nephrology Association

Australian and New Zealand Society of Nephrology

International Society of Pediatric Nephrology

International Society of Nephrology

KIDGEN National Collaborative

Board member of the Alport Foundation of Australia

Themes

Reproductive, Maternal and Child Health

Keywords

Cell biology, Genetic diseases, Nephrology, Proteomics

Approaches

Cellular Signalling, Epidemiology, Genetics

(University of Bristol) Prof Moin Saleem's Academic Renal Unit within the University of Bristol. Previous PhD supervisor. Collaborting on gene discovery projects, rare disease registries and wet lab cell lines work.

Publications

By Type

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Journals

Zhang, J., Skowno, J., Miles, I., Kim, S., Cavazzoni, E., Durkan, A., Hahn, D., McCarthy, H., Alexander, S., Thomas, G., et al (2024). Effect of perioperative management on early graft function in living donor paediatric kidney transplantation. Pediatric Nephrology. [More Information]
Mallawaarachchi, A., Boudville, N., Burke, J., Burnett, L., Casauria, S., Chadban, S., Chakera, A., Crafter, S., Dai, P., De Fazio, P., Tchan, M., McCarthy, H., Alexander, S., et al (2024). Genomic Testing in Patients with Kidney Failure of an Unknown Cause: A National Australian Study. Clinical Journal of the American Society of Nephrology, 19(7), 887-897. [More Information]
Jayasinghe, K., Hahn, D., Rangan, G., Kevin, L., Tchan, M., Snelling, P., Sandow, R., Sundaram, M., Chaturvedi, S., Trnka, P., Bennetts, B., et al (2024). Implementation and Evaluation of a National Multidisciplinary Kidney Genetics Clinic Network Over 10 Years. Kidney International Reports. [More Information]
Mallawaarachchi, A., Goranitis, I., Haas, M., Huntley, V., Jefferis, J., Kassahn, K., Leaver, A., Lundie, B., Lunke, S., O’Connor, C., Amir, N., McCarthy, H., Bennetts, B., et al (2024). Shaping the future of kidney genetics in Australia: proceedings from the KidGen policy implementation workshop 2023. Human Genomics (Online), 18(1), 88. [More Information]
Kermond, R., Mallett, A., McCarthy, H. (2023). A clinical approach to tubulopathies in children and young adults. Pediatric Nephrology, 38(3), 651-662. [More Information]
Malakasioti, G., Iancu, D., Milovanova, A., Tsygin, A., Horinouchi, T., Nagano, C., Nozu, K., Kamei, K., Fujinaga, S., Iijima, K., McCarthy, H., et al (2023). A multicenter retrospective study of calcineurin inhibitors in nephrotic syndrome secondary to podocyte gene variants. Kidney International, 103(5), 962-972. [More Information]
Guha, C., Ahmad, R., Van Zwieten, A., Francis, A., Hawley, C., Jaure, A., Teixeira-Pinto, A., Mallard, A., Bernier-Jean, A., Johnson, D., McCarthy, H., Howard, K., Howell, M., Irving, M., Caldwell, P., Carter, S., et al (2023). Baseline characteristics of participants in the NAVKIDS2 trial: a patient navigator program in children with chronic kidney disease. Pediatric Nephrology, 38(5), 1577-1590. [More Information]
Wu, Y., Mallett, A., Goranitis, I., Jayasinghe, K., Stark, Z., Quinlan, C., Patel, C., McCarthy, H., Mallawaarachchi, A., Kerr, P., Alexander, S. (2023). Genomic testing for suspected monogenic kidney disease in children and adults: A health economic evaluation. Genetics in Medicine, 25(11), 100942. [More Information]
Kermond, R., Ozimek-Kulik, J., Kim, S., Alexander, S., Hahn, D., Kesson, A., Wood, N., McCarthy, H., Durkan, A. (2023). Immunologic response to SARS-CoV-2 mRNA vaccination in pediatric kidney transplant recipients. Pediatric Nephrology, 38(3), 859-866. [More Information]
Larkins, N., Lim, W., Goh, C., Francis, A., McCarthy, H., Kim, S., Wong, G., Craig, J. (2023). Timing of Kidney Replacement Therapy among Children and Young Adults. Clinical Journal of the American Society of Nephrology, 18(8), 1041-1050. [More Information]
Le Marne, F., Briggs, N., Frith, K., Kariyawasam, D., McCarthy, H., Nunn, K., Rao, A., Sachdev, R., Sarkozy, V., Teng, A., et al (2023). Understanding the ongoing learning needs of Australian paediatricians: Evaluation of a pilot paediatric video teaching programme. Journal of Paediatrics and Child Health, 59(2), 307-318. [More Information]
Hoorntje, E., Burns, C., Marsili, L., Corden, B., Parikh, V., Te Meerman, G., Gray, B., Adiyaman, A., Bagnall, R., Barge-Schaapveld, D., et al (2023). Variant Location Is a Novel Risk Factor for Individuals with Arrhythmogenic Cardiomyopathy Due to a Desmoplakin (DSP) Truncating Variant. Circulation. Genomic and Precision Medicine, 16(1), E003672. [More Information]
Bierzynska, A., Bull, K., Miellet, S., Dean, P., Neal, C., Colby, E., McCarthy, H., Hegde, S., Sinha, M., Bugarin Diz, C., et al (2022). Exploring the relevance of NUP93 variants in steroid-resistant nephrotic syndrome using next generation sequencing and a fly kidney model. Pediatric Nephrology, 37(11), 2643-2656. [More Information]
Francis, A., Prestidge, C., Kausman, J., Le Page, A., Larkins, N., McCarthy, H. (2022). Impact of initial steroid response on transplant outcomes in children with steroid-resistant nephrotic syndrome. Pediatric Nephrology, 37(5), 1149-1156. [More Information]
Wang, Y., Shaw, K., Zhang, G., Chung, E., Hu, M., Cao, Q., Wang, Y., Zheng, G., Wu, H., Chadban, S., McCarthy, H., Harris, D., Alexander, S., et al (2022). Interleukin-33 Exacerbates IgA Glomerulonephritis in Transgenic Mice Overexpressing B Cell Activating Factor. Journal of the American Society of Nephrology, 33(5), 966-984. [More Information]
Chung, E., Wang, Y., Keung, K., Hu, M., McCarthy, H., Wong, G., Kairaitis, L., Bose, B., Harris, D., Alexander, S. (2022). Membranous nephropathy: Clearer pathology and mechanisms identify potential strategies for treatment. Frontiers in Immunology, 13, 1036249. [More Information]
Van Zwieten, A., Ryan, E., Caldwell, P., Howard, K., Jaure, A., Craig, J., Alexander, S., Howell, M., Teixeira-Pinto, A., Hawley, C., McCarthy, H., Carter, S., Kim, S., et al (2022). NAVKIDS2 trial: a multi-centre, waitlisted randomised controlled trial of a patient navigator intervention in children with chronic kidney disease — statistical analysis plan and update to the protocol. Trials, 23(1). [More Information]
O’Shea, R., Wood, A., Patel, C., McCarthy, H., Mallawaarachchi, A., Quinlan, C., Simons, C., Stark, Z., Mallett, A. (2022). Participant Choice towards Receiving Potential Additional Findings in an Australian Nephrology Research Genomics Study. Genes, 13(10). [More Information]
Chung, E., Blazek, K., Teixeira-Pinto, A., Sharma, A., Kim, S., Lin, Y., Keung, K., Bose, B., Kairaitis, L., McCarthy, H., Wong, G., et al (2022). Predictive Models for Recurrent Membranous Nephropathy after Kidney Transplantation. Transplantation Direct, 8(9), E1357. [More Information]
Amir, N., McCarthy, H., Jaure, A. (2021). A working partnership: A review of shared decision-making in nephrology. Nephrology, 26(11), 851-857. [More Information]
Tanudisastro, H., Holman, K., Ho, G., Farnsworth, E., Fisk, K., Gayagay, T., Hackett, E., Jenkins, G., Krishnaraj, R., Lai, T., Bennetts, B., Alexander, S., McCarthy, H., et al (2021). Australia and New Zealand renal gene panel testing in routine clinical practice of 542 families. npj Genomic Medicine, 6(1), 20. [More Information]
Amir, N., McCarthy, H., Jaure, A. (2021). Qualitative Research in Nephrology: An Introduction to Methods and Critical Appraisal. Kidney360, 2(4), 737-741. [More Information]
Tan, P., Mallitt, K., McCarthy, H., Kennedy, S. (2021). The impact of caring for children with posterior urethral valves. Acta Paediatrica, 110(3), 1025-1031. [More Information]
Amir, N., Jaure, A., McCarthy, H., Howell, M. (2021). Trajectories of quality of life in chronic kidney disease: a novel perspective of disease progression. Nephrology Dialysis Transplantation, 36(9), 1563-1565. [More Information]
Jones, L., Lam, R., McKee, K., Aleksandrova, M., Dowling, J., Alexander, S., Mallawaarachchi, A., Cottle, D., Short, K., Pais, L., McCarthy, H., et al (2020). A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder. Development, 147(21). [More Information]
Raaijmakers, A., Craig, E., Kim, S., Kennedy, S., McCarthy, H. (2020). Adrenocorticotrophic Hormone-Induced Remission of Pediatric Post-transplantation Recurrent Focal Segmental Glomerulosclerosis. Kidney International Reports, 5(2), 239-243. [More Information]
Jayasinghe, K., Stark, Z., Patel, C., Mallawaarachchi, A., McCarthy, H., Faull, R., Chakera, A., Sundaram, M., Jose, M., Kerr, P., et al (2019). Comprehensive evaluation of a prospective Australian patient cohort with suspected genetic kidney disease undergoing clinical genomic testing: A study protocol. BMJ Open, 9(8), 1-8. [More Information]
Gray, P., McCarthy, H., Siggs, O., Saleem, M., O' Brien, T., Frith, K., Ziegler, J., Kitching, A., Fogo, A., Hudson, B., et al (2019). Molecular Analysis of Goodpasture’s Disease Following Hematopoietic Stem Cell Transplant in a Pediatric Patient, Recalls the Conformeropathy of Wild-Type Anti-GBM Disease. Frontiers in Immunology, 10. [More Information]
Francis, A., Didsbury, M., McCarthy, H., Kara, T. (2018). Treatment of recurrent focal segmental glomerulosclerosis post-kidney transplantation in Australian and New Zealand children: A retrospective cohort study. Pediatric Transplantation, 22(5), 1-7. [More Information]
Bierzynska, A., McCarthy, H., Soderquest, K., Sen, E., Colby, E., Ding, W., Nabhan, M., Kerecuk, L., Hegde, S., Hughes, D., et al (2017). Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management. Kidney International, 91(4), 937-947. [More Information]
Bierzynska, A., Soderquest, K., Dean, P., Colby, E., Rollason, R., Jones, C., Inward, C., McCarthy, H., Simpson, M., et al (2017). MAGI2 Mutations Cause Congenital Nephrotic Syndrome. Journal of the American Society of Nephrology, 28(5), 1614-1621. [More Information]
Mallett, A., McCarthy, H., Ho, G., Holman, K., Farnsworth, E., Patel, C., Fletcher, J., Mallawaarachchi, A., Quinlan, C., Bennetts, B., Alexander, S. (2017). Massively parallel sequencing and targeted exomes in familial kidney disease can diagnose underlying genetic disorders. Kidney International, 92(6), 1493-1506. [More Information]
Ebarasi, L., Ashraf, S., Bierzynska, A., Gee, H., McCarthy, H., Lovric, S., Sadowski, C., Pabst, W., Vega-Warner, V., et al (2015). Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome. American Journal of Human Genetics, 96(1), 153-161. [More Information]
Mallett, A., Corney, C., McCarthy, H., Alexander, S., Healy, H. (2015). Genomics in the renal clinic-translating nephrogenetics for clinical practice. Human Genomics (Online), 9(1), 1-4. [More Information]
Ding, W., Koziell, A., McCarthy, H., Bierzynska, A., Bhagavatula, M., Dudley, J., Inward, C., Coward, R., Tizard, E., et al (2014). Initial steroid sensitivity in children with steroid-resistant nephrotic syndrome predicts post-transplant recurrence. Journal of the American Society of Nephrology, 25(6), 1342-1348. [More Information]
Harris, J., McCarthy, H., Ni, L., Wherlock, M., Kang, H., Wetzels, J., Welsh, G., Saleem, M. (2013). Active proteases in nephrotic plasma lead to a podocin-dependent phosphorylation of VASP in podocytes via protease activated receptor-1. Journal of Pathology, 229(5), 660-671. [More Information]
McCarthy, H., Bierzynska, A., Wherlock, M., Ognjanovic, M., Kerecuk, L., Hegde, S., Feather, S., Gilbert, R., Krischock, L., Jones, C., et al (2013). Simultaneous Sequencing of 24 Genes Associated with Steroid-Resistant Nephrotic Syndrome. Clinical Journal of the American Society of Nephrology, 8(4), 637-648. [More Information]
McCarthy, H., Saleem, M. (2011). Genetics in clinical practice: nephrotic and proteinuric syndromes. Nephron Experimental Nephrology, 118(1), e1-e8. [More Information]
McCarthy, H., Inward, C., Marriage, S., Astley, P., Tizard, E. (2011). Red cell exchange transfusion as a rescue therapy for tacrolimus toxicity in a paediatric renal transplant. Pediatric Nephrology, 26(12), 2245-2248. [More Information]
McCarthy, H., Tizard, E. (2010). Clinical practice: diagnosis and management of Henoch-Schonlein purpura. European Journal of Pediatrics, 169(6), 643-650. [More Information]
Edwards, A., McCarthy, H., Morgan, J., Saleem, M. (2010). Paediatric non-heart-beating renal transplantation. Archives of Disease in Childhood, 95(10), 843-844. [More Information]

show 38 more

By Year

Expand all

2024

Zhang, J., Skowno, J., Miles, I., Kim, S., Cavazzoni, E., Durkan, A., Hahn, D., McCarthy, H., Alexander, S., Thomas, G., et al (2024). Effect of perioperative management on early graft function in living donor paediatric kidney transplantation. Pediatric Nephrology. [More Information]
Mallawaarachchi, A., Boudville, N., Burke, J., Burnett, L., Casauria, S., Chadban, S., Chakera, A., Crafter, S., Dai, P., De Fazio, P., Tchan, M., McCarthy, H., Alexander, S., et al (2024). Genomic Testing in Patients with Kidney Failure of an Unknown Cause: A National Australian Study. Clinical Journal of the American Society of Nephrology, 19(7), 887-897. [More Information]
Jayasinghe, K., Hahn, D., Rangan, G., Kevin, L., Tchan, M., Snelling, P., Sandow, R., Sundaram, M., Chaturvedi, S., Trnka, P., Bennetts, B., et al (2024). Implementation and Evaluation of a National Multidisciplinary Kidney Genetics Clinic Network Over 10 Years. Kidney International Reports. [More Information]
Mallawaarachchi, A., Goranitis, I., Haas, M., Huntley, V., Jefferis, J., Kassahn, K., Leaver, A., Lundie, B., Lunke, S., O’Connor, C., Amir, N., McCarthy, H., Bennetts, B., et al (2024). Shaping the future of kidney genetics in Australia: proceedings from the KidGen policy implementation workshop 2023. Human Genomics (Online), 18(1), 88. [More Information]

show 1 more

2023

Kermond, R., Mallett, A., McCarthy, H. (2023). A clinical approach to tubulopathies in children and young adults. Pediatric Nephrology, 38(3), 651-662. [More Information]
Malakasioti, G., Iancu, D., Milovanova, A., Tsygin, A., Horinouchi, T., Nagano, C., Nozu, K., Kamei, K., Fujinaga, S., Iijima, K., McCarthy, H., et al (2023). A multicenter retrospective study of calcineurin inhibitors in nephrotic syndrome secondary to podocyte gene variants. Kidney International, 103(5), 962-972. [More Information]
Guha, C., Ahmad, R., Van Zwieten, A., Francis, A., Hawley, C., Jaure, A., Teixeira-Pinto, A., Mallard, A., Bernier-Jean, A., Johnson, D., McCarthy, H., Howard, K., Howell, M., Irving, M., Caldwell, P., Carter, S., et al (2023). Baseline characteristics of participants in the NAVKIDS2 trial: a patient navigator program in children with chronic kidney disease. Pediatric Nephrology, 38(5), 1577-1590. [More Information]
Wu, Y., Mallett, A., Goranitis, I., Jayasinghe, K., Stark, Z., Quinlan, C., Patel, C., McCarthy, H., Mallawaarachchi, A., Kerr, P., Alexander, S. (2023). Genomic testing for suspected monogenic kidney disease in children and adults: A health economic evaluation. Genetics in Medicine, 25(11), 100942. [More Information]
Kermond, R., Ozimek-Kulik, J., Kim, S., Alexander, S., Hahn, D., Kesson, A., Wood, N., McCarthy, H., Durkan, A. (2023). Immunologic response to SARS-CoV-2 mRNA vaccination in pediatric kidney transplant recipients. Pediatric Nephrology, 38(3), 859-866. [More Information]
Larkins, N., Lim, W., Goh, C., Francis, A., McCarthy, H., Kim, S., Wong, G., Craig, J. (2023). Timing of Kidney Replacement Therapy among Children and Young Adults. Clinical Journal of the American Society of Nephrology, 18(8), 1041-1050. [More Information]
Le Marne, F., Briggs, N., Frith, K., Kariyawasam, D., McCarthy, H., Nunn, K., Rao, A., Sachdev, R., Sarkozy, V., Teng, A., et al (2023). Understanding the ongoing learning needs of Australian paediatricians: Evaluation of a pilot paediatric video teaching programme. Journal of Paediatrics and Child Health, 59(2), 307-318. [More Information]
Hoorntje, E., Burns, C., Marsili, L., Corden, B., Parikh, V., Te Meerman, G., Gray, B., Adiyaman, A., Bagnall, R., Barge-Schaapveld, D., et al (2023). Variant Location Is a Novel Risk Factor for Individuals with Arrhythmogenic Cardiomyopathy Due to a Desmoplakin (DSP) Truncating Variant. Circulation. Genomic and Precision Medicine, 16(1), E003672. [More Information]

show 5 more

2022

Bierzynska, A., Bull, K., Miellet, S., Dean, P., Neal, C., Colby, E., McCarthy, H., Hegde, S., Sinha, M., Bugarin Diz, C., et al (2022). Exploring the relevance of NUP93 variants in steroid-resistant nephrotic syndrome using next generation sequencing and a fly kidney model. Pediatric Nephrology, 37(11), 2643-2656. [More Information]
Francis, A., Prestidge, C., Kausman, J., Le Page, A., Larkins, N., McCarthy, H. (2022). Impact of initial steroid response on transplant outcomes in children with steroid-resistant nephrotic syndrome. Pediatric Nephrology, 37(5), 1149-1156. [More Information]
Wang, Y., Shaw, K., Zhang, G., Chung, E., Hu, M., Cao, Q., Wang, Y., Zheng, G., Wu, H., Chadban, S., McCarthy, H., Harris, D., Alexander, S., et al (2022). Interleukin-33 Exacerbates IgA Glomerulonephritis in Transgenic Mice Overexpressing B Cell Activating Factor. Journal of the American Society of Nephrology, 33(5), 966-984. [More Information]
Chung, E., Wang, Y., Keung, K., Hu, M., McCarthy, H., Wong, G., Kairaitis, L., Bose, B., Harris, D., Alexander, S. (2022). Membranous nephropathy: Clearer pathology and mechanisms identify potential strategies for treatment. Frontiers in Immunology, 13, 1036249. [More Information]
Van Zwieten, A., Ryan, E., Caldwell, P., Howard, K., Jaure, A., Craig, J., Alexander, S., Howell, M., Teixeira-Pinto, A., Hawley, C., McCarthy, H., Carter, S., Kim, S., et al (2022). NAVKIDS2 trial: a multi-centre, waitlisted randomised controlled trial of a patient navigator intervention in children with chronic kidney disease — statistical analysis plan and update to the protocol. Trials, 23(1). [More Information]
O’Shea, R., Wood, A., Patel, C., McCarthy, H., Mallawaarachchi, A., Quinlan, C., Simons, C., Stark, Z., Mallett, A. (2022). Participant Choice towards Receiving Potential Additional Findings in an Australian Nephrology Research Genomics Study. Genes, 13(10). [More Information]
Chung, E., Blazek, K., Teixeira-Pinto, A., Sharma, A., Kim, S., Lin, Y., Keung, K., Bose, B., Kairaitis, L., McCarthy, H., Wong, G., et al (2022). Predictive Models for Recurrent Membranous Nephropathy after Kidney Transplantation. Transplantation Direct, 8(9), E1357. [More Information]

show 4 more

2021

Amir, N., McCarthy, H., Jaure, A. (2021). A working partnership: A review of shared decision-making in nephrology. Nephrology, 26(11), 851-857. [More Information]
Tanudisastro, H., Holman, K., Ho, G., Farnsworth, E., Fisk, K., Gayagay, T., Hackett, E., Jenkins, G., Krishnaraj, R., Lai, T., Bennetts, B., Alexander, S., McCarthy, H., et al (2021). Australia and New Zealand renal gene panel testing in routine clinical practice of 542 families. npj Genomic Medicine, 6(1), 20. [More Information]
Amir, N., McCarthy, H., Jaure, A. (2021). Qualitative Research in Nephrology: An Introduction to Methods and Critical Appraisal. Kidney360, 2(4), 737-741. [More Information]
Tan, P., Mallitt, K., McCarthy, H., Kennedy, S. (2021). The impact of caring for children with posterior urethral valves. Acta Paediatrica, 110(3), 1025-1031. [More Information]
Amir, N., Jaure, A., McCarthy, H., Howell, M. (2021). Trajectories of quality of life in chronic kidney disease: a novel perspective of disease progression. Nephrology Dialysis Transplantation, 36(9), 1563-1565. [More Information]

show 2 more

2020

Jones, L., Lam, R., McKee, K., Aleksandrova, M., Dowling, J., Alexander, S., Mallawaarachchi, A., Cottle, D., Short, K., Pais, L., McCarthy, H., et al (2020). A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder. Development, 147(21). [More Information]
Raaijmakers, A., Craig, E., Kim, S., Kennedy, S., McCarthy, H. (2020). Adrenocorticotrophic Hormone-Induced Remission of Pediatric Post-transplantation Recurrent Focal Segmental Glomerulosclerosis. Kidney International Reports, 5(2), 239-243. [More Information]

2019

Jayasinghe, K., Stark, Z., Patel, C., Mallawaarachchi, A., McCarthy, H., Faull, R., Chakera, A., Sundaram, M., Jose, M., Kerr, P., et al (2019). Comprehensive evaluation of a prospective Australian patient cohort with suspected genetic kidney disease undergoing clinical genomic testing: A study protocol. BMJ Open, 9(8), 1-8. [More Information]
Gray, P., McCarthy, H., Siggs, O., Saleem, M., O' Brien, T., Frith, K., Ziegler, J., Kitching, A., Fogo, A., Hudson, B., et al (2019). Molecular Analysis of Goodpasture’s Disease Following Hematopoietic Stem Cell Transplant in a Pediatric Patient, Recalls the Conformeropathy of Wild-Type Anti-GBM Disease. Frontiers in Immunology, 10. [More Information]

2018

Francis, A., Didsbury, M., McCarthy, H., Kara, T. (2018). Treatment of recurrent focal segmental glomerulosclerosis post-kidney transplantation in Australian and New Zealand children: A retrospective cohort study. Pediatric Transplantation, 22(5), 1-7. [More Information]

2017

Bierzynska, A., McCarthy, H., Soderquest, K., Sen, E., Colby, E., Ding, W., Nabhan, M., Kerecuk, L., Hegde, S., Hughes, D., et al (2017). Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management. Kidney International, 91(4), 937-947. [More Information]
Bierzynska, A., Soderquest, K., Dean, P., Colby, E., Rollason, R., Jones, C., Inward, C., McCarthy, H., Simpson, M., et al (2017). MAGI2 Mutations Cause Congenital Nephrotic Syndrome. Journal of the American Society of Nephrology, 28(5), 1614-1621. [More Information]
Mallett, A., McCarthy, H., Ho, G., Holman, K., Farnsworth, E., Patel, C., Fletcher, J., Mallawaarachchi, A., Quinlan, C., Bennetts, B., Alexander, S. (2017). Massively parallel sequencing and targeted exomes in familial kidney disease can diagnose underlying genetic disorders. Kidney International, 92(6), 1493-1506. [More Information]

2015

Ebarasi, L., Ashraf, S., Bierzynska, A., Gee, H., McCarthy, H., Lovric, S., Sadowski, C., Pabst, W., Vega-Warner, V., et al (2015). Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome. American Journal of Human Genetics, 96(1), 153-161. [More Information]
Mallett, A., Corney, C., McCarthy, H., Alexander, S., Healy, H. (2015). Genomics in the renal clinic-translating nephrogenetics for clinical practice. Human Genomics (Online), 9(1), 1-4. [More Information]

2014

Ding, W., Koziell, A., McCarthy, H., Bierzynska, A., Bhagavatula, M., Dudley, J., Inward, C., Coward, R., Tizard, E., et al (2014). Initial steroid sensitivity in children with steroid-resistant nephrotic syndrome predicts post-transplant recurrence. Journal of the American Society of Nephrology, 25(6), 1342-1348. [More Information]

2013

Harris, J., McCarthy, H., Ni, L., Wherlock, M., Kang, H., Wetzels, J., Welsh, G., Saleem, M. (2013). Active proteases in nephrotic plasma lead to a podocin-dependent phosphorylation of VASP in podocytes via protease activated receptor-1. Journal of Pathology, 229(5), 660-671. [More Information]
McCarthy, H., Bierzynska, A., Wherlock, M., Ognjanovic, M., Kerecuk, L., Hegde, S., Feather, S., Gilbert, R., Krischock, L., Jones, C., et al (2013). Simultaneous Sequencing of 24 Genes Associated with Steroid-Resistant Nephrotic Syndrome. Clinical Journal of the American Society of Nephrology, 8(4), 637-648. [More Information]

2011

McCarthy, H., Saleem, M. (2011). Genetics in clinical practice: nephrotic and proteinuric syndromes. Nephron Experimental Nephrology, 118(1), e1-e8. [More Information]
McCarthy, H., Inward, C., Marriage, S., Astley, P., Tizard, E. (2011). Red cell exchange transfusion as a rescue therapy for tacrolimus toxicity in a paediatric renal transplant. Pediatric Nephrology, 26(12), 2245-2248. [More Information]

2010

McCarthy, H., Tizard, E. (2010). Clinical practice: diagnosis and management of Henoch-Schonlein purpura. European Journal of Pediatrics, 169(6), 643-650. [More Information]
Edwards, A., McCarthy, H., Morgan, J., Saleem, M. (2010). Paediatric non-heart-beating renal transplantation. Archives of Disease in Childhood, 95(10), 843-844. [More Information]

Faculty of Medicine and Health

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Dr Hugh McCarthy

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