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Professor Emeritus John Chalmers
AC
Emeritus Professor
Medicine, Central Clinical School
Medicine, Central Clinical School
Large scale clinical trials and epidemiological studies in relation to hypertension, to coronary heart disease and stroke, and to diabetes and renal disease. Particular focus on international studies that include low and middle income countries as well as countries with advanced economies.
Obesity, Diabetes and Cardiovascular Disease, Healthy Ageing, Lifespan
Selected publications
Clinician's Manual on Blood Pressure and Stroke Prevention
(Current Medicine Group Ltd., 2002)
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Publications
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Books
- Chalmers, J., Colagiuri, S., Cooper, M., Grobbee, R., Hamet, P., Kengne, A., MacMahon, S., Marre, M., Mogensen, C., Neal, B., Patel, A., Perkovic, V., et al (2008). Prevention of vascular outcomes in type 2 diabetes: benefits of intensive blood pressure and blood glucose control with Preterax and Diamicron MR. France: Wolters Kluwer Health France.
- Chalmers, J. (2007). ADVANCE: New Approaches for the prevention of Vascular Disease in Type 2 Diabetes. Issue 1. France: Wolters Kluwer Health France.
Edited Books
- Chalmers, J., Colagiuri, S., Grobbee, R., Hamet, P., Kengne, A., MacMahon, S., Mogensen, C., Neal, B., Patel, A., Perkovic, V., et al (2007). New approaches for the prevention of vascular disease in type 2 diabetes: benefits of blood pressure lowering with the fixed combination of perindopril and indapamide. France: Wolters Kluwer Health Pharma Solutions.
- Chalmers, J., MacMahon, S., Brass, L., Chapman, N., Gorelick, P., Neal, B. (2002). Clinician's Manual on Blood Pressure and Stroke Prevention. United Kingdom: Current Medicine Group Ltd.
Book Chapters
- Chapman, N., Arima, H., Chalmers, J., Anderson, C. (2012). Cerebrovascular Disease in Hypertension. In Henry R Black and William J Elliott (Eds.), Hypertension: A Companion to Braunwald's Heart Disease, Second Edition, (pp. 392-405). Philadelphia: Elsevier. [More Information]
- Hata, J., Arima, H., Anderson, C., Chalmers, J. (2012). Cognitive Function and Dementia in Hypertension: Epidemiologic and Therapeutic Aspects. In Adel E. Berbari and Giuseppe Mancia (Eds.), Special Issues in Hypertension, (pp. 399-412). Milan, Italy: Springer. [More Information]
- Chalmers, J., Cooper, M., Grobbee, R., Hamet, P., Kengne, A., MacMahon, S., Marre, M., Mogensen, C., Neal, B., Patel, A., et al (2010). Protection against cardiovascular and renal disease in type 2 diabetes: ADVANCEs in the control of blood pressure Peterax and Diamicron MR. In J Chalmers (Eds.), Action in Diabetes and Vascular Disease: Preterax and Diamicron Mr Controlled Evaluation. France: Wolters Kluwer Health France.
- Perkovic, V., Ninomiya, T., MacMahon, S., Chalmers, J. (2009). Renal and microalbuminuria data from ADVANCE. In Bernard I. Levy, Harry A.J. Struijker-Boudier (Eds.), Role of Macro and Microcirculation in Target Organ Damage in Diabetes and Hypertension, (pp. 121-132). West Sussex: Wiley-Blackwell Publishing.
- Chalmers, J. (2008). Prevention of stroke and major cardiovascular events with perindopril-based treatment: the PROGRESS trial. In R. Ferrari and K. M. Fox (Eds.), Perindopril: a major contribution to the prevention and treatment of cardiovascular disease, (pp. 47-58). France: Wolters Kluwer Health Pharma Solutions.
- Chalmers, J., Turnbull, F. (2006). Blood Pressure Lowering in Patients with a Previous Stroke. In Mohler E; Townsend R (Eds.), Advanced Therapy in Hypertension and Vascular Disease, (pp. 130-135). Ontario, Canada: BC Decker Inc.
- Chalmers, J., Chapman, N. (2004). Development Of Blood Pressure Lowering Therapy: From Trials To Practice. In WH Birkenhager, JIS Robertson, A Zanchetti (Eds.), Hypertension in the Twentieth Century: Concepts and Achievements; Handbook of Hypertension, (pp. 504-525). Amsterdam, The Netherlands: Elsevier.
- Chalmers, J., Morniroli, J. (2004). The Kidney and Hypertension in Diabetes Mellitus. In Carl Erik Mogensen (Eds.), Blood Pressure Lowering Treatment And The Prevention Of Stroke In The Diabetic Patient, (pp. 611-630). London: Taylor and Francis.
- Chalmers, J., MacMahon, S., Currie, R. (2003). PROGRESS: Rationale, results and importance: Perspective from the Principle Investigators. In Teruo Omae (Eds.), How to conduct large-scaled clinical trials in Japan, (pp. 51-55). Japan: Nihon Iji Shinpo.
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Journals
- Wang, N., Woodward, M., Chalmers, J., Harris, K., Poulter, N., Mancia, G., Harrap, S., Hamet, P., Grobbee, D., Marre, M. (2024). Combination blood pressure lowering therapy in patients with type 2 diabetes: messages from the ADVANCE trial. Journal of Hypertension, , 10.1097/HJH.0000000000003855. [More Information]
- Neuen, B., Jun, M., Wick, J., Kotwal, S., Badve, S., Jardine, M., Gallagher, M., Chalmers, J., Nallaiah, K., Perkovic, V., et al (2024). Estimating the population-level impacts of improved uptake of SGLT2 inhibitors in patients with chronic kidney disease: a cross-sectional observational study using routinely collected Australian primary care data. The Lancet Regional Health. Western Pacific, 43. [More Information]
- Chen, C., Robinson, T., Lindley, R., Arima, H., Chalmers, J., Li, G., Chen, X., Anderson, C., Song, L., Ren, X., et al (2024). Intensive Blood Pressure Lowering and Renal Function in Ischemic Stroke Patients: Secondary Analysis of the ENCHANTED Trial. Cerebrovascular Diseases. [More Information]
- You, S., Arima, H., Chen, X., Liu, C., Lindley, I., Robinson, T., Anderson, C., Chalmers, J., Zheng, D., Yoshimura, S., et al (2024). Optimum Baseline Clinical Severity Scale Cut Points for Prognosticating Intracerebral Hemorrhage: INTERACT Studies. Stroke, 55(1), 139-145. [More Information]
- Han, Q., Chen, C., Delcourt, C., Zhou, Z., Cao, Y., Liu, C., Zheng, D., Arima, H., Robinson, T., Chen, X., Lindley, R., et al (2024). Predictors of Early versus Delayed Neurological Deterioration after Thrombolysis for Ischemic Stroke. Cerebrovascular Diseases. [More Information]
- Jun, M., Nallaiah, K., Jardine, M., Perkovic, V., Gallagher, M., Ronksley, P., Wick, J., Neuen, B., Kotwal, S., Badve, S., et al (2024). The Prevalence of CKD in Australian Primary Care: Analysis of a National General Practice Dataset. Kidney International Reports, 9(2), 312-322. [More Information]
- Inker, L., Collier, W., Greene, T., Miao, S., Chaudhari, J., Appel, G., Badve, S., Caravaca-Fontán, F., Del Vecchio, L., Floege, J., et al (2023). A meta-analysis of GFR slope as a surrogate endpoint for kidney failure. Nature Medicine, 29(7), 1867-1876. [More Information]
- Wang, N., Harris, K., Woodward, M., Harrap, S., Mancia, G., Poulter, N., Chalmers, J., Rodgers, A. (2023). Clinical Utility of Short-Term Blood Pressure Measures to Inform Long-Term Blood Pressure Management. Hypertension, 80(3), 608-617. [More Information]
- Nolde, J., Atkins, E., Marschner, S., Hillis, G., Chalmers, J., Billot, L., Nelson, M., Reid, C., Hay, P., Burke, M., Usherwood, T., Chow, C., et al (2023). Effect of Initial Treatment With a Single Pill Containing Quadruple Combination of Quarter Doses of Blood Pressure Medicines Versus Standard Dose Monotherapy in Patients With Hypertension on Ambulatory Blood Pressure Indices: Results From the QUARTET Study. Circulation, 148(4), 375-377. [More Information]
- Chen, C., Ouyang, M., Ong, S., Zhang, L., Zhang, G., Delcourt, C., Mair, G., Liu, L., Billot, L., Li, Q., Lindley, R., et al (2023). Effects of intensive blood pressure lowering on cerebral ischaemia in thrombolysed patients: insights from the ENCHANTED trial. EClinicalMedicine, 57. [More Information]
- Wang, X., Minhas, J., Moullaali, T., Di Tanna, G., Lindley, R., Chen, X., Arima, H., Chen, G., Delcourt, C., Bath, P., et al (2022). Associations of Early Systolic Blood Pressure Control and Outcome after Thrombolysis-Eligible Acute Ischemic Stroke: Results from the ENCHANTED Study. Stroke, 29(2), 779-787. [More Information]
- Wang, N., Harris, K., Hamet, P., Harrap, S., Mancia, G., Poulter, N., Williams, B., Zoungas, S., Woodward, M., Chalmers, J., et al (2022). Cumulative Systolic Blood Pressure Load and Cardiovascular Risk in Patients With Diabetes. Journal of the American College of Cardiology, 80(12), 1147-1155. [More Information]
- Moullaali, T., Wang, X., Sandset, E., Woodhouse, L., Law, Z., Arima, H., Butcher, K., Chalmers, J., Delcourt, C., Edwards, L., et al (2022). Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data. Journal of Neurology, Neurosurgery and Psychiatry, 93(1), 6-13. [More Information]
- Nolde, J., Hillis, G., Atkins, E., Von Huben, A., Marschner, S., Chan, J., Reid, C., Nelson, M., Figtree, G., Chalmers, J., Usherwood, T., Chow, C., et al (2022). Impact of various night-time period definitions on nocturnal ambulatory blood pressure. Journal of Hypertension, 40(11), 2271-2279. [More Information]
- Gong, J., Harris, K., Tzourio, C., Harrap, S., Naismith, S., Anderson, C., Chalmers, J., Woodward, M. (2022). Sex differences in predictors for cognitive decline and dementia in people with stroke or transient ischemic attack in the PROGRESS trial. International Journal of Stroke, 17(8), 863-872. [More Information]
- Zhou, Z., Xia, C., Mair, G., Delcourt, C., Yoshimura, S., Liu, X., Chen, Z., Malavera, A., Carcel, C., Chen, X., Lindley, R., et al (2022). Thrombolysis outcomes according to arterial characteristics of acute ischemic stroke by alteplase dose and blood pressure target. International Journal of Stroke, 17(5), 566-575. [More Information]
- Anderson, C., Rodgers, A., De Silva, H., Martins, S., Klijn, C., Senanayake, B., Freed, R., Billot, L., Arima, H., Thang, N., Naismith, S., Lindley, R., Chow, C., et al (2022). Triple Therapy Prevention of Recurrent Intracerebral Disease Events Trial: Rationale, design and progress. International Journal of Stroke, 17(10), 1156-1162. [More Information]
- Song, L., Wang, X., Ouyang, M., Sun, L., Chen, X., Arima, H., Sandset, E., Delcourt, C., Wang, J., Chen, G., Lindley, R., Chalmers, J., Anderson, C., et al (2021). Associations of an Abnormal Physiological Score With Outcomes in Acute Intracerebral Hemorrhage: INTERACT2 Study. Stroke, 52(2), 722-725. [More Information]
- Wang, N., Harris, K., Chalmers, J., Harrap, S., Mancia, G., Marre, M., Poulter, N., Tzourio, C., Williams, B., Zoungas, S., et al (2021). Combination blood pressure lowering in the presence or absence of background statin and aspirin therapy: a combined analysis of PROGRESS and ADVANCE Trials. Journal of Hypertension, 39(8), 1689-1696. [More Information]
- Minhas, J., Wang, X., Lindley, R., Delcourt, C., Song, L., Woodward, M., Lee, T., Broderick, J., Pontes-Neto, O., Kim, J., et al (2021). Comparative effects of intensive-blood pressure versus standard-blood pressure-lowering treatment in patients with severe ischemic stroke in the ENCHANTED trial. Journal of Hypertension, 39(2), 280-285. [More Information]
- Oshima, M., Hara, A., Toyama, T., Jun, M., Pollock, C., Jardine, M., Harrap, S., Poulter, N., Cooper, M., Woodward, M., et al (2021). Comparison of Circulating Biomarkers in Predicting Diabetic Kidney Disease Progression With Autoantibodies to Erythropoietin Receptor. Kidney International Reports, 6(2), 284-295. [More Information]
- Chen, C., Wang, X., Chen, X., Ouyang, M., Sun, L., Arima, H., Robinson, T., Lindley, R., Chalmers, J., Li, G., Anderson, C., et al (2021). Disparities between Asian and Non-Asian Thrombolyzed Acute Ischemic Stroke Patients in the Enhanced Control of Hypertension and Thrombolysis Stroke Trial. Cerebrovascular Diseases, 50(5), 560-566. [More Information]
- Chow, C., Atkins, E., Hillis, G., Nelson, M., Reid, C., Schlaich, M., Hay, P., Rogers, K., Billot, L., Burke, M., Usherwood, T., et al (2021). Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial. The Lancet, 398(10305), 1043-1052. [More Information]
- Zhou, Z., Xia, C., Carcel, C., Yoshimura, S., Wang, X., Delcourt, C., Malavera, A., Chen, X., Mair, G., Woodward, M., et al (2021). Intensive versus guideline-recommended blood pressure reduction in acute lacunar stroke with intravenous thrombolysis therapy: The ENCHANTED trial. European Journal of Neurology, 28(3), 783-793. [More Information]
- Zhou, Z., Delcourt, C., Xia, C., Yoshimura, S., Carcel, C., Torii-Yoshimura, T., You, S., Malavera, A., Chen, X., Hackett, M., et al (2021). Low-Dose vs Standard-Dose Alteplase in Acute Lacunar Ischemic Stroke: The ENCHANTED Trial. Neurology, 96(11), e1512-e1526. [More Information]
- Tremblay, J., Haloui, M., Attaoua, R., Tahir, R., Hishmih, C., Harvey, F., Marois-Blanchet, F., Long, C., Simon, P., Santucci, L., Colagiuri, S., et al (2021). Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control. Diabetologia, 64(9), 2012-2025. [More Information]
- Chen, C., Song, L., Yang, J., Lindley, R., Robinson, T., Arima, H., Chalmers, J., Anderson, C., Wang, X. (2021). Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials. Frontiers in Neurology, 12, 687862. [More Information]
- Sun, L., Song, L., Yang, J., Lindley, R., Robinson, T., Lavados, P., Delcourt, C., Arima, H., Ovbiagele, B., Chalmers, J., et al (2021). Smoking influences outcome in patients who had thrombolysed ischaemic stroke: The ENCHANTED study. Stroke and Vascular Neurology, 6(3), 395-401. [More Information]
- Woodhouse, L., Montgomery, A., Mant, J., Davis, B., Algra, A., Mas, J., Staessen, J., Thijs, L., Tonkin, A., Kirby, A., et al (2021). Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials. BMC Medical Research Methodology, 21(1), 218. [More Information]
- Huang, L., Neal, B., Wu, J., Huang, Y., Marklund, M., Campbell, N., He, F., Yoshimura, S., Chalmers, J., Trieu, K. (2021). The impact of baseline potassium intake on the dose–response relation between sodium reduction and blood pressure change: systematic review and meta-analysis of randomized trials. Journal of Human Hypertension, 35(11), 946-957. [More Information]
- Chow, C., Atkins, E., Billot, L., Chalmers, J., Hillis, G., Hay, P., Neal, B., Nelson, M., Patel, A., Reid, C., Usherwood, T., Rodgers, A., et al (2021). Ultra-low-dose quadruple combination blood pressure–lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol. American Heart Journal, 231, 56-67. [More Information]
- Chen, X., Li, J., Anderson, C., Lindley, R., Hackett, M., Robinson, T., Lavados, P., Wang, X., Arima, H., Chalmers, J., Delcourt, C. (2021). Validation of the simplified modified Rankin scale for stroke trials: Experience from the ENCHANTED alteplase-dose arm. International Journal of Stroke, 16(2), 222-228. [More Information]
- Jun, M., Harris, K., Heerspink, H., Badve, S., Jardine, M., Harrap, S., Hamet, P., Marre, M., Poulter, N., Kotwal, S., Gallagher, M., et al (2021). Variability in estimated glomerular filtration rate and the risk of major clinical outcomes in diabetes: Post hoc analysis from the ADVANCE trial. Diabetes, Obesity and Metabolism, 23(6), 1420-1425. [More Information]
- Chen, X., Delcourt, C., Sun, L., Zhou, Z., Yoshimura, S., You, S., Malavera, A., Torii-Yoshimura, T., Carcel, C., Arima, H., Hackett, M., Song, L., Lindley, R., Anderson, C., et al (2020). Brain Imaging Signs and Health-Related Quality of Life after Acute Ischemic Stroke: Analysis of ENCHANTED Alteplase Dose Arm. Cerebrovascular Diseases, 49(4), 427-436. [More Information]
- Hua, X., Lung, T., Woodward, M., Salomon, J., Hamet, P., Harrap, S., Mancia, G., Poulter, N., Chalmers, J., Clarke, P. (2020). Self-rated health scores predict mortality among people with type 2 diabetes differently across three different country groupings: findings from the ADVANCE and ADVANCE-ON trials. Diabetic Medicine, 37(8), 1379-1385. [More Information]
- Sandset, E., Wang, X., Carcel, C., Sato, S., Delcourt, C., Arima, H., Stapf, C., Robinson, T., Lavados, P., Chalmers, J., et al (2020). Sex differences in treatment, radiological features and outcome after intracerebral haemorrhage: Pooled analysis of Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage trials 1 and 2. European Stroke Journal, 5(4), 345-350. [More Information]
- Zhou, Z., Yoshimura, S., Delcourt, C., You, S., Malavera, A., Lindley, R., Torii-Yoshimura, T., Wang, X., Chen, X., Parsons, M., Carcel, C., et al (2020). Thrombolysis Outcomes in Acute Ischemic Stroke by Fluid-Attenuated Inversion Recovery Hyperintense Arteries. Stroke, 51(7), 2240-2243. [More Information]
- Wang, X., Moullaali, T., Li, Q., Berge, E., Robinson, T., Lindley, R., Zheng, D., Delcourt, C., Arima, H., Song, L., et al (2020). Utility-Weighted Modified Rankin Scale Scores for the Assessment of Stroke Outcome: Pooled Analysis of 20 000+ Patients. Stroke, 51(8), 2411-2417. [More Information]
- Robinson, T., Bray, B., Paley, L., Sprigg, N., Wang, X., Arima, H., Bath, P., Broderick, J., Durham, A., Kim, J., et al (2019). Applicability of ENCHANTED trial results to current acute ischemic stroke patients eligible for intravenous thrombolysis in England and Wales: Comparison with the Sentinel Stroke National Audit Programme registry. International Journal of Stroke, 14(7), 678-685. [More Information]
- You, S., Zheng, D., Delcourt, C., Sato, S., Cao, Y., Zhang, S., Yang, J., Wang, X., Lindley, R., Robinson, T., et al (2019). Determinants of Early Versus Delayed Neurological Deterioration in Intracerebral Hemorrhage. Stroke, 50(6), 1409-1414. [More Information]
- Wang, X., Sandset, E., Moullaali, T., Chen, G., Song, L., Carcel, C., Delcourt, C., Woodward, M., Robinson, T., Chalmers, J., Anderson, C., et al (2019). Determinants of the high admission blood pressure in mild-to-moderate acute intracerebral hemorrhage. Journal of Hypertension, 37(7), 1463-1466. [More Information]
- Zhang, Z., Tremblay, J., Raelson, J., Sofer, T., Du, L., Fang, Q., Argos, M., Marois-Blanchet, F., Wang, Y., Yan, L., Chalmers, J., Woodward, M., et al (2019). EPHA4 regulates vascular smooth muscle cell contractility and is a sex-specific hypertension risk gene in individuals with type 2 diabetes. Journal of Hypertension, 37(4), 775-789. [More Information]
- Santo, K., Singleton, A., Rogers, K., Thiagalingam, A., Chalmers, J., Chow, C., Redfern, J. (2019). Medication reminder applications to improve adherence in coronary heart disease: a randomised clinical trial. Heart, 105(4), 323-329. [More Information]
- Carcel, C., Wang, X., Sandset, E., Delcourt, C., Arima, H., Lindley, R., Hackett, M., Lavados, P., Robinson, T., Muñoz Venturelli, P., Anderson, C., et al (2019). Sex differences in treatment and outcome after stroke: Pooled analysis including 19,000 participants. Neurology, 93(24), e2170-e2180. [More Information]
- Robinson, T., Wang, X., Durham, A., Ford, G., Liao, J., Littlewood, S., Roffe, C., White, P., Chalmers, J., Anderson, C. (2019). The National Institute for Health Research Hyperacute Stroke Research Centres and the ENCHANTED trial: The impact of enhanced research infrastructure on trial metrics and patient outcomes. Health Research Policy and Systems, 17(1). [More Information]
- Mohammedi, K., Chalmers, J., Herrington, W., Li, Q., Mancia, G., Marre, M., Poulter, N., Rodgers, A., Williams, B., Perkovic, V., Woodward, M., et al (2018). Associations between body mass index and the risk of renal events in patients with type 2 diabetes. Nutrition and Diabetes, 8(1), 1-9. [More Information]
- Ohkuma, T., Woodward, M., Chalmers, J. (2018). Cardiac stress and inflammatory markers as predictors of heart failure in patients with type 2 diabetes: The ADVANCE trial. Diabetes care 2017;40:1203-1209. Diabetes Care, 41(3), e39. [More Information]
- Jun, M., Ohkuma, T., Zoungas, S., Colagiuri, S., Mancia, G., Marre, M., Matthews, D., Poulter, N., Williams, B., Rodgers, A., Perkovic, V., et al (2018). Changes in Albuminuria and the Risk of Major Clinical Outcomes in Diabetes: Results From ADVANCE-ON. Diabetes Care, 41(1), 163-170. [More Information]
- Welsh, P., Rankin, N., Li, Q., Mark, P., Wurtz, P., Ala-Korpela, M., Marre, M., Poulter, N., Hamet, P., Chalmers, J., et al (2018). Circulating amino acids and the risk of macrovascular, microvascular and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial. Diabetologia, 61(7), 1581-1591. [More Information]
- Nagel, S., Wang, X., Carcel, C., Robinson, T., Lindley, R., Chalmers, J., Anderson, C. (2018). Clinical Utility of Electronic Alberta Stroke Program Early Computed Tomography Score Software in the ENCHANTED Trial Database. Stroke, 49(6), 1407-1411. [More Information]
- Chen, G., Wang, X., Robinson, T., Pikkemaat, M., Lindley, R., Zhou, S., Ping, L., Liu, W., Liu, L., Chalmers, J., et al (2018). Comparative effects of low-dose versus standard-dose alteplase in ischemic patients with prior stroke and/or diabetes mellitus: The ENCHANTED trial. Journal of the Neurological Sciences, 387, 1-5. [More Information]
- Wang, X., You, S., Sato, S., Yang, J., Carcel, C., Zheng, D., Yoshimura, S., Anderson, C., Sandset, E., Robinson, T., Chalmers, J., et al (2018). Current status of intravenous tissue plasminogen activator dosage for acute ischaemic stroke: an updated systematic review. Stroke and Vascular Neurology, 3(1), 28-33. [More Information]
- van Steen, S., Woodward, M., Chalmers, J., Li, Q., Marre, M., Cooper, M., Hamet, P., Mancia, G., Colagiuri, S., Williams, B., et al (2018). Haemoglobin glycation index and risk for diabetes-related complications in the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial. Diabetologia, 61(4), 780-789. [More Information]
- Mundra, P., Barlow, C., Nestel, P., Barnes, E., Kirby, A., Thompson, P., Sullivan, D., Alshehry, Z., Mellett, N., Huynh, K., Simes, R., et al (2018). Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention. JCI Insight, 3(17), e121326. [More Information]
- Kim, J., Kim, Y., Lee, K., Cha, J., Park, J., Hwang, Y., Kim, E., Rha, J., Koo, J., Kim, J., Lindley, R., Wang, X., Chalmers, J., Anderson, C., et al (2018). Low- versus Standard-Dose Intravenous Alteplase in the Context of Bridging Therapy for Acute Ischemic Stroke: A Korean ENCHANTED Study. Journal of Stroke, 20(1), 131-139. [More Information]
- Anderson, C., Woodward, M., Chalmers, J. (2018). More on Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke. New England Journal of Medicine, 378(15), 1465-1466. [More Information]
- Yoshimura, S., Lindley, R., Carcel, C., Sato, S., Delcourt, C., Wang, X., Chalmers, J., Anderson, C. (2018). NIHSS cut point for predicting outcome in supra- vs infratentorial acute ischemic stroke. Neurology, 91(18), e1695-e1701. [More Information]
- Nowson, C., Lim, K., Land, M., Webster, J., Shaw, J., Chalmers, J., Flood, V., Woodward, M., Grimes, C. (2018). Salt intake and dietary sources of salt on week days and weekend days in Australian adults. Public Health Nutrition, 21(12), 2174-2182. [More Information]
- Santo, K., Hyun, K., de Keizer, L., Thiagalingam, A., Hillis, G., Chalmers, J., Redfern, J., Chow, C. (2018). The effects of a lifestyle-focused text-messaging intervention on adherence to dietary guideline recommendations in patients with coronary heart disease: An analysis of the TEXT ME study. International Journal of Behavioral Nutrition and Physical Activity, 15(1), 1-11. [More Information]
- Delcourt, C., Zheng, D., Chen, X., Hackett, M., Arima, H., Hata, J., Heeley, E., Salman, R., Woodward, M., Huang, Y., Lindley, R., Davies, L., Chalmers, J., Anderson, C., Sato, S., et al (2017). Associations with health-related quality of life after intracerebral haemorrhage: pooled analysis of INTERACT studies. Journal of Neurology, Neurosurgery and Psychiatry, 88(1), 70-75. [More Information]
- Schilling, C., Knight, J., Mortimer, D., Petrie, D., Clarke, P., Chalmers, J., Kerr, A., Jackson, R. (2017). Australian general practitioners initiate statin therapy primarily on the basis of lipid levels; New Zealand general practitioners use absolute risk. Health Policy, 121(12), 1233-1239. [More Information]
- Ohkuma, T., Jun, M., Woodward, M., Zoungas, S., Cooper, M., Grobbee, D., Hamet, P., Mancia, G., Williams, B., Welsh, P., Chalmers, J., et al (2017). Cardiac stress and inflammatory markers as predictors of heart failure in patients with type 2 diabetes: The ADVANCE trial. Diabetes Care, 40(9), 1203-1209. [More Information]
- Song, L., Wang, X., Robinson, T., Lindley, R., Arima, H., Lavados, P., Chen, X., Chalmers, J., Anderson, C. (2017). Characteristics, management and response to alteplase in China versus non-China participants of the ENCHANTED trial. Stroke and Vascular Neurology, 2(2), 53-58. [More Information]
- Mohammedi, K., Woodward, M., Marre, M., Colagiuri, S., Cooper, M., Harrap, S., Mancia, G., Poulter, N., Williams, B., Zoungas, S., Chalmers, J. (2017). Comparative effects of microvascular and macrovascular disease on the risk of major outcomes in patients with type 2 diabetes. Cardiovascular Diabetology, 16(1), 1-9. [More Information]
- Hirakawa, Y., Arima, H., Rodgers, A., Woodward, M., Chalmers, J. (2017). Cumulative in-trial and post-trial effects of blood pressure and lipid lowering: systematic review and meta-analysis. Journal of Hypertension, 35(5), 905-913. [More Information]
- Santos, J., Webster, J., Land, M., Flood, V., Chalmers, J., Woodward, M., Neal, B., Petersen, K. (2017). Dietary salt intake in the Australian population. Public Health Nutrition, 20(11), 1887-1894. [More Information]
- You, S., Wang, X., Lindley, R., Robinson, T., Anderson, C., Cao, Y., Chalmers, J. (2017). Early Cognitive Impairment after Intracerebral Hemorrhage in the INTERACT1 Study. Cerebrovascular Diseases, 44(5-6), 320-324. [More Information]
- Zoungas, S., Arima, H., Gerstein, H., Holman, R., Woodward, M., Reaven, P., Hayward, R., Craven, T., Coleman, R., Chalmers, J. (2017). Effects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: a meta-analysis of individual participant data from randomised controlled trials. The Lancet Diabetes and Endocrinology, 5(6), 431-437. [More Information]
- Bennett, A., Chow, C., Chou, M., Dehbi, H., Webster, R., Salam, A., Patel, A., Neal, B., Peiris, D., Thakkar, J., Chalmers, J., Woodward, M., Hilmer, S., Usherwood, T., Rodgers, A., et al (2017). Efficacy and Safety of Quarter-Dose Blood Pressure-Lowering Agents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Hypertension, 70(1), 85-93. [More Information]
- Richtering, S., Hyun, K., Neubeck, A., Coorey, G., Chalmers, J., Usherwood, T., Peiris, D., Chow, C., Redfern, J. (2017). eHealth Literacy: Predictors in a Population With Moderate-to-High Cardiovascular Risk. JMIR Human Factors, 4(1), e4. [More Information]
- Tremblay, J., Wang, Y., Raelson, J., Marois-Blanchet, F., Wu, Z., Luo, H., Bradley, E., Chalmers, J., Woodward, M., Harrap, S., et al (2017). Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene. Scientific Reports, 7, 1-10. [More Information]
- Richtering, S., Morris, R., Soh, S., Barker, A., Bampi, F., Neubeck, A., Coorey, G., Mulley, J., Chalmers, J., Usherwood, T., Peiris, D., Chow, C., Redfern, J. (2017). Examination of an eHealth literacy scale and a health literacy scale in a population with moderate to high cardiovascular risk: Rasch analyses. PloS One, 12(4), 1-14. [More Information]
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- Delcourt, C., Sato, S., Zhang, S., Sandset, E., Zheng, D., Chen, X., Hackett, M., Arima, H., Hata, J., Heeley, E., Davies, L., Lindley, R., Chalmers, J., Anderson, C., et al (2017). Intracerebral hemorrhage location and outcome among INTERACT2 participants. Neurology, 88(15), 1408-1414. [More Information]
- Wang, X., Robinson, T., Lee, T., Li, Q., Arima, H., Bath, P., Billot, L., Broderick, J., Demchuk, A., Donnan, G., Lindley, R., Woodward, M., Anderson, C., Chalmers, J., et al (2017). Low-dose vs standard-dose alteplase for patients with acute ischemic stroke: Secondary analysis of the ENCHANTED randomized clinical trial. JAMA Neurology, 74(11), 1328-1335. [More Information]
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- Qiu, M., Sato, S., Zheng, D., Wang, X., Carcel, C., Hirakawa, Y., Sandset, E., Delcourt, C., Arima, H., Wang, J., Chalmers, J., Anderson, C. (2016). Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies. Stroke, 47(6), 1479-1485. [More Information]
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- Hayes, A., Arima, H., Woodward, M., Chalmers, J., Poulter, N., Hamet, P., Clarke, P. (2016). Changes in Quality of Life Associated with Complications of Diabetes: Results from the ADVANCE Study. Value in Health, 19(1), 36-41. [More Information]
- Wong, G., Staplin, N., Emberson, J., Baigent, C., Turner, R., Chalmers, J., Zoungas, S., Pollock, C., Cooper, B., Harris, D., Wang, J., Mitchell, P., Chapman, J., Craig, J., et al (2016). Chronic kidney disease and the risk of cancer: An individual patient data meta-analysis of 32,057 participants from six prospective studies. BMC Cancer, 16(1), 1-11. [More Information]
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- Radholm, K., Arima, H., Lindley, R., Wang, J., Tzourio, C., Robinson, T., Heeley, E., Anderson, C., Chalmers, J. (2015). Older age is a strong predictor for poor outcome in intracerebral haemorrhage: the INTERACT2 study. Age and Ageing, 44(3), 422-427. [More Information]
- Arima, H., Heeley, E., Delcourt, C., Hirakawa, Y., Wang, X., Woodward, M., Robinson, T., Stapf, C., Parsons, M., Lavados, P., Chalmers, J., Anderson, C., et al (2015). Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2. Neurology, 84(5), 464-471. [More Information]
- Heeley, E., Anderson, C., Woodward, M., Arima, H., Robinson, T., Stapf, C., Parsons, M., Lavados, P., Huang, Y., Wang, Y., Chalmers, J., et al (2015). Poor utility of grading scales in acute intracerebral hemorrhage: Results from the INTERACT2 trial. International Journal of Stroke, 10(7), 1101-1107. [More Information]
- van der Leeuw, J., Visseren, F., Woodward, M., Zoungas, S., Kengne, A., van der Graaf, Y., Glasziou, P., Hamet, P., MacMahon, S., Poulter, N., Chalmers, J., et al (2015). Predicting the Effects of Blood Pressure-Lowering Treatment on Major Cardiovascular Events for Individual Patients With Type 2 Diabetes Mellitus: Results From Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation. Hypertension, 65(1), 115-121. [More Information]
- Yang, J., Arima, H., Wu, G., Heeley, E., Delcourt, C., Zhou, J., Chen, G., Wang, X., Zhang, S., Yu, S., Chalmers, J., Anderson, C. (2015). Prognostic significance of perihematomal edema in acute intracerebral hemorrhage: pooled analysis from the intensive blood pressure reduction in acute cerebral hemorrhage trial studies. Stroke, 46(4), 1009-1013. [More Information]
- Huang, Y., Sharma, V., Robinson, T., Lindley, R., Chen, X., Kim, J., Lavados, P., Olavarria, V., Arima, H., Fuentes, S., Woodward, M., Chalmers, J., Anderson, C., et al (2015). Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2-2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment. International Journal of Stroke, 10(5), 778-788. [More Information]
- Chan, E., Anderson, C., Wang, X., Arima, H., Saxena, A., Moullaali, T., Heeley, E., Delcourt, C., Wu, G., Wang, J., Chalmers, J., et al (2015). Significance of intraventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial results. Stroke, 46(3), 653-658. [More Information]
- Anderson, C., Woodward, M., Arima, H., Chen, X., Lindley, R., Wang, X., Chalmers, J. (2015). Statistical analysis plan for evaluating low- vs. standard-dose alteplase in the ENhanced Control of Hypertension and Thrombolysis strokE stuDy (ENCHANTED). International Journal of Stroke, 10(8), 1313-1315. [More Information]
- Poppe, K., Whalley, G., Doughty, R., Woodward, M., Patel, A., Chow, C., Hirakawa, Y., Chalmers, J., Hillis, G., Triggs, C. (2015). The development and feasibility of a composite score of echocardiographic indices that may stratify outcome in patients with diabetes mellitus. International Journal of Cardiology, 182, 244-249. [More Information]
- Knott, R., Petrie, D., Heeley, E., Chalmers, J., Clarke, P. (2015). The effects of reduced copayments on discontinuation and adherence failure to statin medication in Australia. Health Policy, 119, 620-627. [More Information]
- Thomas, M., Woodward, M., Neal, B., Li, Q., Pickering, R., Marre, M., Williams, B., Perkovic, V., Cooper, M., Zoungas, S., Chalmers, J., Hillis, G. (2015). The Relationship Between Levels of Advanced Glycation End-Products and Their Soluble Receptor and Adverse Outcomes in Adults With Type 2 Diabetes. Diabetes Care, 38(10), 1891-1897. [More Information]
- Wolff, M., Memon, A., Chalmers, J., Sundquist, K., Midlov, P. (2015). Yoga's effect on inflammatory biomarkers and metabolic risk factors in a high risk population - a controlled trial in primary care. BMC Cardiovascular Disorders, 15(1), 1-7. [More Information]
- Fischer, U., Cooney, M., Bull, L., Silver, L., Chalmers, J., Anderson, C., Mehta, Z., Rothwell, P. (2014). Acute post-stroke blood pressure relative to premorbid levels in intracerebral haemorrhage versus major ischaemic stroke: a population-based study. The Lancet Neurology, 13(4), 374-384. [More Information]
- Zheng, D., Arima, H., Heeley, E., Karpin, A., Heller, G., Yang, J., Chalmers, J., Anderson, C. (2014). Ambient Temperature and Severity of Intracerebral Haemorrhage: The INTERACT1 Study. Neuroepidemiology, 42(3), 169-173. [More Information]
- Chalmers, J. (2014). Are the effects of telmisartan more marked in hypertensive patients? Journal of Hypertension, 32(6), 1201-1202. [More Information]
- Gottesman, R., Chalmers, J. (2014). Blood pressure and cerebral ischemia: a continuing dilemma. Neurology, 82(12), 1018-1019. [More Information]
- Manning, L., Hirakawa, Y., Arima, H., Wang, X., Chalmers, J., Wang, J., Lindley, R., Heeley, E., Delcourt, C., Neal, B., Woodward, M., Anderson, C., et al (2014). Blood pressure variability and outcome after acute intracerebral haemorrhage: a post-hoc analysis of INTERACT2, a randomised controlled trial. The Lancet Neurology, 13(4), 364-373. [More Information]
- Lowe, G., Woodward, M., Hillis, G., Rumley, A., Li, Q., Harrap, S., Marre, M., Hamet, P., Patel, A., Poulter, N., Chalmers, J. (2014). Circulating Inflammatory Markers and the Risk of Vascular Complications and Mortality in People With Type 2 Diabetes and Cardiovascular Disease or Risk Factors: The ADVANCE Study. Diabetes, 63(3), 1115-1123. [More Information]
- Weber, M., Schiffrin, E., White, W., Mann, S., Lindholm, L., Kenerson, J., Flack, J., Carter, B., Materson, B., Ram, C., Chalmers, J., et al (2014). Clinical Practice Guidelines for the Management of Hypertension in the Community. A Statement by the American Society of Hypertension and the International Society of Hypertension. Journal of Hypertension, 32(1), 3-15. [More Information]
- Weber, M., Schiffrin, E., White, W., Mann, S., Lindholm, L., Kenerson, J., Flack, J., Carter, B., Materson, B., Ram, C., Chalmers, J., et al (2014). Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. Journal of Clinical Hypertension, 16(1), 14-26. [More Information]
- Arima, H., Anderson, C., Omae, T., Woodward, M., MacMahon, S., Mancia, G., Bousser, M., Tzourio, C., Harrap, S., Liu, L., Neal, B., Chalmers, J. (2014). Degree of blood pressure reduction and recurrent stroke: the PROGRESS trial. Journal of Neurology, Neurosurgery and Psychiatry, 85, 1284-1285. [More Information]
- Welsh, P., Woodward, M., Hillis, G., Li, Q., Marre, M., Williams, B., Poulter, N., Ryan, L., Harrap, S., Patel, A., Chalmers, J., et al (2014). Do Cardiac Biomarkers NT-proBNP and hsTnT Predict Microvascular Events in Patients With Type 2 Diabetes? Results From the ADVANCE Trial. Diabetes Care, 37(8), 2202-2210. [More Information]
- Chalmers, J., Arima, H., Woodward, M., Mancia, G., Poulter, N., Hirakawa, Y., Zoungas, S., Patel, A., Williams, B., Harrap, S. (2014). Effects of Combination of Perindopril, Indapamide, and Calcium Channel Blockers in Patients With Type 2 Diabetes Mellitus: Results From the Action in Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) Trial. Hypertension, 63(2), 259-264. [More Information]
- Zoungas, S., Chalmers, J., Neal, B., Billot, L., Li, Q., Hirakawa, Y., Arima, H., Monaghan, H., Joshi, R., Colagiuri, S., Perkovic, V., Rodgers, A., MacMahon, S., Patel, A., Woodward, M., et al (2014). Follow-up of blood-pressure lowering and glucose control in type 2 diabetes. New England Journal of Medicine, 371(15), 1392-1406. [More Information]
- Chalmers, J. (2014). How far to lower blood pressure in the long term, after a stroke? Journal of Hypertension, 32(4), 746-748. [More Information]
- Zoungas, S., Woodward, M., Li, Q., Cooper, M., Hamet, P., Harrap, S., Heller, S., Marre, M., Patel, A., Poulter, N., Chalmers, J., et al (2014). Impact of age, age at diagnosis and duration of diabetes on the risk of macrovascular and microvascular complications and death in type 2 diabetes. Diabetologia, 57(12), 2465-2474. [More Information]
- Hirakawa, Y., Arima, H., Zoungas, S., Ninomiya, T., Cooper, M., Hamet, P., Mancia, G., Poulter, N., Harrap, S., Woodward, M., Chalmers, J. (2014). Impact of Visit-to-Visit Glycemic Variability on the Risks of Macrovascular and Microvascular Events and All-Cause Mortality in Type 2 Diabetes: The ADVANCE Trial. Diabetes Care, 37(8), 2359-2365. [More Information]
- Van Dieren, S., Kengne, A., Chalmers, J., Beulens, J., Davis, T., Fulcher, G., Heller, S., Patel, A., Colagiuri, S., Hamet, P., Neal, B., Woodward, M., Zoungas, S., et al (2014). Intensification of medication and glycaemic control among patients with type 2 diabetes - the ADVANCE trial. Diabetes, Obesity and Metabolism, 16(5), 426-432. [More Information]
- Land, M., Jeffery, P., Webster, J., Crino, M., Chalmers, J., Woodward, M., Nowson,, C., Smith, W., Flood, V., Neal, B. (2014). Protocol for the implementation and evaluation of a community-based intervention seeking to reduce dietary salt intake in Lithgow, Australia. BMC Public Health, 14(1), 1-7. [More Information]
- Hillis, G., Welsh, P., Chalmers, J., Woodward, M., Sattar, N. (2014). Response to comment on hillis et Al. The relative and combined ability of high-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic Peptide to predict cardiovascular events and death in patients with type 2 diabetes. Diabetes care 2014;37:295-303. Diabetes Care, 37(6), e154-e154. [More Information]
- Ding, D., Rogers, K., Macniven, R., Kamalesh, V., Kritharides, L., Chalmers, J., Bauman, A. (2014). Revisiting Lifestyle Risk Index Assessment in a Large Australian Sample: Are Sedentary Behavior and Sleep Correlated with Health Outcomes. Preventive Medicine, 60, 102-106. [More Information]
- Land, M., Webster, J., Christoforou, A., Praveen, D., Jeffery, P., Chalmers, J., Smith, W., Woodward, M., Barzi, F., Nowson,, C., Neal, B., et al (2014). Salt intake assessed by 24 h urinary sodium excretion in a random and opportunistic sample in Australia. BMJ Open, 4(2), 1-7. [More Information]
- Chen, G., Arima, H., Wu, G., Heeley, E., Delcourt, C., Zhang, P., Rabinstein, A., Robinson, T., Stapf, C., Huang, Y., Song, L., Yang, J., Wang, X., Li, Q., Chen, X., Chalmers, J., Anderson, C. (2014). Subarachnoid Extension of Intracerebral Hemorrhage and 90-Day Outcomes in INTERACT2. Stroke, 45(1), 258-260. [More Information]
- Land, M., Webster, J., Christoforou, A., Johnson, C., Trevena, H., Hodgins, F., Chalmers, J., Woodward, M., Barzi, F., Smith, W., Flood, V., Neal, B., et al (2014). The association of knowledge, attitudes and behaviours related to salt with 24-hour urinary sodium excretion. International Journal of Behavioral Nutrition and Physical Activity, 11(1), 1-8. [More Information]
- Brughts, J., Arima, H., Remme, W., Bertrand, M., Ferrari, R., Fox, K., DiNicolantonio, J., MacMahon, S., Chalmers, J., Zijlstra, F., et al (2014). The incidence and clinical predictors of ACE-inhibitor induced dry cough by perindopril in 27,492 patients with vascular disease. International Journal of Cardiology, 176(3), 718-723. [More Information]
- Blomster, J., Zoungas, S., Chalmers, J., Li, Q., Chow, C., Woodward, M., Mancia, G., Poulter, N., Williams, B., Harrap, S., Neal, B., et al (2014). The relationship between alcohol consumption and vascular complications and mortality in individuals with type 2 diabetes. Diabetes Care, 37(5), 1353-1359. [More Information]
- Hillis, G., Welsh, P., Chalmers, J., Perkovic, V., Chow, C., Li, Q., Jun, M., Neal, B., Zoungas, S., Poulter, N., Woodward, M., et al (2014). The relative and combined ability of high sensitivity cardiac troponin T and N-terminal pro-B-type Natriuretic Peptide to predict cardiovascular events and death in patients with type 2 diabetes. Diabetes Care, 37(1), 295-303. [More Information]
- Sato, S., Arima, H., Hirakawa, Y., Heeley, E., Delcourt, C., Beer, R., Li, Y., Zhang, J., Juettler, E., Wang, J., Lindley, R., Chalmers, J., Anderson, C., et al (2014). The speed of ultraearly hematoma growth in acute intracerebral hemorrhage. Neurology, 83(24), 2232-2238. [More Information]
- Rist, P., Chalmers, J., Arima, H., Anderson, C., MacMahon, S., Woodward, M., Kurth, T., Tzourio, C. (2013). Baseline Cognitive Function, Recurrent Stroke, and Risk of Dementia in Patients With Stroke. Stroke, 44(7), 1790-1795. [More Information]
- Ninomiya, T., Perkovic, V., Turnbull, F., Neal, B., Barzi, F., Cass, A., Baigent, C., Chalmers, J., Li, N., Woodward, M., MacMahon, S. (2013). Blood pressure lowering and major cardiovascular events in people with and without chronic kidney disease: meta-analysis of randomised controlled trials. BMJ, 347(7929), 1-15. [More Information]
- Perkovic, V., Woodward, M., Zoungas, S., Chalmers, J. (2013). Caution advised in interpreting nonsignificant results from ADVANCE post hoc analysis. Kidney International, 84(3), 622-622. [More Information]
- Wong, M., Perkovic, V., Woodward, M., Chalmers, J., Li, Q., Hillis, G., Azari, E., Jun, M., Poulter, N., Hamet, P., Neal, B., Pollock, C., et al (2013). Circulating bone morphogenetic protein-7 and transforming growth factor-(beta)1 are better predictors of renal end points in patients with type 2 diabetes mellitus. Kidney International, 83(2), 278-284. [More Information]
- Chalmers, J. (2013). Current issues with dual inhibition of the renin-angiotensin system. Journal of Hypertension, 31(2), 261-262. [More Information]
- Hata, J., Arima, H., Zoungas, S., Fulcher, G., Pollock, C., Adams, M., Watson, J., Joshi, R., Kengne, A., Ninomiya, T., Anderson, C., Woodward, M., Patel, A., MacMahon, S., Chalmers, J., Neal, B., et al (2013). Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial. PloS One, 8(2), 1-7. [More Information]
- Hata, J., Arima, H., Rothwell, P., Woodward, M., Zoungas, S., Anderson, C., Patel, A., Neal, B., Glasziou, P., Hamet, P., MacMahon, S., Chalmers, J., et al (2013). Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: The ADVANCE trial. Circulation, 128(12), 1325-1334. [More Information]
- Banks, E., Joshy, G., Abhayaratna, W., Kritharides, L., MacDonald, P., Korda, R., Chalmers, J. (2013). Erectile Dysfunction Severity as a Risk Marker for Cardiovascular Disease Hospitalisation and All-Cause Mortality: A Prospective Cohort Study. PLoS Medicine, 10(1), 1-13. [More Information]
- Chalmers, J., Arima, H., Harrap, S., Touyz, R., Park, J. (2013). Global survey of current practice in management of hypertension as reported by societies affiliated with the international society of hypertension. Journal of Hypertension, 31(5), 1043-1048. [More Information]
- Perkovic, V., Heerspink, H., Chalmers, J., Woodward, M., Jun, M., Li, Q., MacMahon, S., Cooper, M., Hamet, P., Marre, M., Cass, A., Patel, A., Zoungas, S., et al (2013). Intensive glucose control improves kidney outcomes in patients with type 2 diabetes. Kidney International, 83(3), 517-523. [More Information]
- Batty, G., Li, Q., Huxley, R., Zoungas, S., Taylor, B., Neal, B., de Galan, B., Woodward, M., Harrap, S., Colagiuri, S., Patel, A., Chalmers, J. (2013). Oral disease in relation to future risk of dementia and cognitive decline: Prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial. European Psychiatry, 28(1), 49-52. [More Information]
- Chalmers, J., Angus, J., Graham, R., Carmody, J., Dampney, R., Jennings, G., Korner, N. (2013). Paul Ivan Korner 1925-2012. Historical Records of Australian Science, 24(2), 251-282. [More Information]
- Anderson, C., Heeley, E., Huang, Y., Wang, J., Stapf, C., Delcourt, C., Lindley, R., Robinson, T., Lavados, P., Neal, B., Hata, J., Arima, H., Heritier, S., Li, Q., Woodward, M., Simes, R., Chalmers, J., et al (2013). Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage. New England Journal of Medicine, 368(25), 2355-2365. [More Information]
- Anderson, C., Heeley, E., Heritier, S., Arima, H., Woodward, M., Lindley, R., Neal, B., Huang, Y., Wang, J., Parsons, M., Delcourt, C., Chalmers, J., et al (2013). Statistical analysis plan for the second INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT2): a large-scale investigation to solve longstanding controversy over the most appropriate management of elevated blood pressure in the hyperacute phase of intracerebral hemorrhage. International Journal of Stroke, 8(5), 327-328. [More Information]
- Morton, J., Ng, M., Chalmers, J., Woodward, M., Mancia, G., Poulter, N., Marre, M., Cooper, M., Zoungas, S. (2013). The Association of High-Density Lipoprotein Cholesterol with Cancer Incidence in Type II Diabetes: A Case of Reverse Causality? Cancer Epidemiology Biomarkers and Prevention, 22(9), 1628-1633. [More Information]
- Justin Zaman, M., Patel, A., Chalmers, J., Woodward, M., Clarke, P., Li, Q., Zoungas, S. (2013). The effects of patient characteristics and geographical region on hospitalization in patients with Type 2 diabetes. Diabetic Medicine, 30(8), 918-925. [More Information]
- Blomster, J., Chow, C., Zoungas, S., Woodward, M., Patel, A., Poulter, N., Marre, M., Harrap, S., Chalmers, J., Hillis, G. (2013). The influence of physical activity on vascular complications and mortality in patients with type 2 diabetes mellitus. Diabetes, Obesity and Metabolism, 15(11), 1008-1012. [More Information]
- Stefansdottir, G., Zoungas, S., Chalmers, J., Knol, M., Leufkens, H., Woodward, M., Patel, A., Grobbee, D., De Bruin, M. (2013). The Post Hoc Use of Randomised Controlled Trials to Explore Drug Associated Cancer Outcomes: Methodological Challenges. Current Drug Safety, 8(5), 371-378. [More Information]
- Zoungas, S., Chalmers, J., Li, Q., Woodward, M. (2012). ADVANCE and glycaemia thresholds: a need to clarify the statistical approach. Reply to Currie CJ [letter]. Diabetologia, 55(8), 2300-2300. [More Information]
- Zoungas, S., Chalmers, J., Ninomiya, T., Li, Q., Cooper, M., Colagiuri, S., Fulcher, G., de Galan, B., Harrap, S., Hamet, P., Patel, A., Neal, B., Woodward, M., et al (2012). Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Diabetologia, 55(3), 636-643. [More Information]
- Fox, C., Matsushita, K., Woodward, M., Bilo, H., Chalmers, J., Heerspink, H., Lee, B., Perkins, R., Rossing, P., Sairenchi, T., et al (2012). Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. The Lancet, 380(9854), 1662-1673. [More Information]
- Razavian, M., Heeley, E., Perkovic, V., Zoungas, S., Weekes, A., Patel, A., Anderson, C., Chalmers, J., Cass, A. (2012). Cardiovascular risk management in chronic kidney disease in general practice (the AusHEART study). Nephrology Dialysis Transplantation, 27(4), 1396-1402. [More Information]
- Chalmers, J., Arima, H., Hata, J. (2012). Cost-effective reduction in stroke: lessons from the Japanese hypertension detection and control program. Journal of Hypertension, 30(9), 1706-1707. [More Information]
- Heeley, E., Anderson, C., Patel, A., Cass, A., Peiris, D., Weekes, A., Chalmers, J. (2012). Disparities between prescribing of secondary prevention therapies for stroke and coronary artery disease in general practice. International Journal of Stroke, 7(8), 649-654. [More Information]
- Arima, H., Huang, Y., Wang, J., Heeley, E., Delcourt, C., Parsons, M., Li, Q., Neal, B., Chalmers, J., Anderson, C. (2012). Earlier Blood Pressure-Lowering and Greater Attenuation of Hematoma Growth in Acute Intracerebral Hemorrhage: INTERACT Pilot Phase. Stroke, 43(8), 2236-2238. [More Information]
- Van Dieren, S., Kengne, A., Chalmers, J., Beulens, J., Cooper, M., Grobbee, D., Harrap, S., Mancia, G., Neal, B., Patel, A., Woodward, M., Zoungas, S., et al (2012). Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk groups among participants with type 2 diabetes. Diabetes Research and Clinical Practice, 98(1), 83-90. [More Information]
- Arima, H., Anderson, C., Omae, T., Woodward, M., MacMahon, S., Mancia, G., Bousser, M., Tzourio, C., Rodgers, A., Neal, B., Chalmers, J. (2012). Effects of Blood Pressure Lowering on Intracranial and Extracranial Bleeding in Patients on Antithrombotic Therapy: The PROGRESS Trial. Stroke, 43(6), 1675-1677. [More Information]
- Lv, J., Neal, B., Ehteshami, P., Ninomiya, T., Woodward, M., Rodgers, A., Wang, H., MacMahon, S., Turnbull, F., Hillis, G., Chalmers, J., Perkovic, V. (2012). Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis. PLoS Medicine, 9(8), 1-14. [More Information]
- Salvi, E., Kutalik, Z., Glorioso, N., Benaglio, P., Frau, F., Kuznetsova, T., Arima, H., Hoggart, C., Tichet, J., Nikitin, Y., Chalmers, J., et al (2012). Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase. Hypertension, 59(2), 248-255. [More Information]
- Zoungas, S., Chalmers, J. (2012). Glycemic control and outcomes in people with diabetes and CKD. Nature Reviews Nephrology, 8(3), 133-134. [More Information]
- Delcourt, C., Huang, Y., Arima, H., Chalmers, J., Davis, S., Heeley, E., Wang, J., Parsons, M., Liu, G., Anderson, C. (2012). Hematoma growth and outcomes in intracerebral hemorrhage: The INTERACT1 study. Neurology, 79(4), 314-319. [More Information]
- Knott, R., Cass, A., Heeley, E., Chalmers, J., Peiris, D., Clarke, P. (2012). How fair is Medicare? The income-related distribution of Medicare benefits with special focus on chronic care items. Medical Journal of Australia, 197(11/12), 1-5. [More Information]
- Morton, J., Zoungas, S., Li, Q., Patel, A., Chalmers, J., Woodward, M., Celermajer, D., Beulens, J., Stolk, R., Glasziou, P., Ng, M. (2012). Low HDL Cholesterol and the Risk of Diabetic Nephropathy and Retinopathy: Results of the ADVANCE study. Diabetes Care, 35(11), 2201-2206. [More Information]
- Chalmers, J. (2012). Making Good Use of Diastolic and Systolic Blood Pressures in the Management of Hypertension. Hypertension, 60(5), 1110-1111. [More Information]
- Kengne, A., Sobngwi, E., Chalmers, J. (2012). Multiple risk factor interventions and inflammatory biomarkers in high risk individuals with type 2 diabetes. Diabetes Research and Clinical Practice, 95(3), 386-388. [More Information]
- Jardine, M., Hata, J., Woodward, M., Perkovic, V., Ninomiya, T., Arima, H., Zoungas, S., Cass, A., Patel, A., Marre, M., Chalmers, J., et al (2012). Prediction of Kidney-Related Outcomes in Patients With Type 2 Diabetes. American Journal of Kidney Diseases, 60(5), 770-778. [More Information]
- Hillis, G., Woodward, M., Rodgers, A., Chow, C., Li, Q., Zoungas, S., Patel, A., Webster, R., Batty, G., Ninomiya, T., Chalmers, J., et al (2012). Resting heart rate and the risk of death and cardiovascular complications in patients with type 2 diabetes mellitus. Diabetologia, 55(5), 1283-1290. [More Information]
- Hillis, G., Hata, J., Woodward, M., Perkovic, V., Arima, H., Chow, C., Zoungas, S., Patel, A., Poulter, N., Mancia, G., Chalmers, J., et al (2012). Resting Heart Rate and the Risk of Microvascular Complications in Patients With Type 2 Diabetes Mellitus. Journal of the American Heart Association, 1(5), 1-11. [More Information]
- Wong, G., Zoungas, S., Lo, S., Chalmers, J., Cass, A., Neal, B., Woodward, M., Perkovic, V., Glasziou, P., Williams, B., Howard, K., Chapman, J., Craig, J. (2012). The risk of cancer in people with diabetes and chronic kidney disease. Nephrology Dialysis Transplantation, 27(8), 3337-3344. [More Information]
- Van Dieren, S., Czernichow, S., Chalmers, J., Kengne, A., de Galan, B., Poulter, N., Woodward, M., Beulens, J., Grobbee, D., van der Schouw, Y., Zoungas, S. (2012). Weight changes and their predictors amongst 11 140 patients with type 2 diabetes in the ADVANCE trial. Diabetes, Obesity and Metabolism, 14(5), 464-469. [More Information]
- Brugts, J., Isaacs, A., de Maat, M., Boersma, E., van Duijn, C., Akkerhuis, K., Uitterlinden, A., Witteman, J., Cambien, F., Ceconi, C., Ninomiya, T., Chalmers, J., MacMahon, S., et al (2011). A Pharmacogenetic Analysis of Determinants of Hypertension and Blood Pressure Response to Angiotensin-Converting Enzyme Inhibitor Therapy in Patients With Vascular Disease and Healthy Individuals. Journal of Hypertension, 29(3), 509-519. [More Information]
- Salomon, J., Patel, A., Neal, B., Glasziou, P., Grobbee, D., Chalmers, J., Clarke, P. (2011). Comparability of Patient-reported Health Status: Multicountry Analysis of EQ-5D Responses in Patients With Type 2 Diabetes. Medical Care, 49(10), 962-969. [More Information]
- Czernichow, S., Kengne, A., Huxley, R., Batty, G., de Galan, B., Grobbee, D., Pillai, A., Zoungas, S., Marre, M., Woodward, M., Neal, B., Chalmers, J. (2011). Comparison of waist-to-hip ratio and other obesity indices as predictors of cardiovascular disease risk in people with type-2 diabetes: a prospective cohort study from ADVANCE. European Journal of Cardiovascular Prevention and Rehabilitation, 18(2), 312-319. [More Information]
- Kengne, A., Patel, A., Marre, M., Travert, F., Lievre, M., Zoungas, S., Chalmers, J., Colagiuri, S., Grobbee, D., Hamet, P., Neal, B., Woodward, M., et al (2011). Contemporary model for cardiovascular risk prediction in people with type 2 diabetes. European Journal of Cardiovascular Prevention and Rehabilitation, 18(3), 393-398. [More Information]
- Woodward, M., Patel, A., Zoungas, S., Liu, L., Pan, C., Poulter, N., Januszewicz, A., Tandon, N., Joshi, P., Heller, S., Neal, B., Chalmers, J. (2011). Does Glycemic Control Offer Similar Benefits Among Patients With Diabetes in Different Regions of the World?: Results from the ADVANCE trial. Diabetes Care, 34(12), 2491-2495. [More Information]
- Arima, H., Anderson, C., Omae, T., Woodward, M., Hata, J., Murakami, Y., MacMahon, S., Neal, B., Chalmers, J., PROGRESS Collaborative Group, -. (2011). Effects of Blood Pressure Lowering on Major Vascular Events Among Patients With Isolated Diastolic Hypertension: The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) Trial. Stroke, 42(8), 2339-2341. [More Information]
- Turnbull, F., Arima, H., Heeley, E., Cass, A., Chalmers, J., Morgan, C., Patel, A., Peiris, D., Weekes, A., Anderson, C. (2011). Gender disparities in the assessment and management of cardiovascular risk in primary care: the AusHEART study. European Journal of Cardiovascular Prevention and Rehabilitation, 18(3), 498-503. [More Information]
- Stefansdottir, G., Zoungas, S., Chalmers, J., Kengne, A., Knol, M., Leufkens, H., Patel, A., Woodward, M., Grobbee, D., De Bruin, M. (2011). Intensive glucose control and risk of cancer in patients with type 2 diabetes. Diabetologia, 54(7), 1608-1614. [More Information]
- Chalmers, J. (2011). Is a Blood Pressure Target of <130/80 mm Hg Still Appropriate for High-Risk Patients? Circulation, 124(16), 1700-1702. [More Information]
- Lee, P., Kengne, A., Greenfield, J., Day, R., Chalmers, J., Ho, K. (2011). Metabolic sequelae of β-blocker therapy: weighing in on the obesity epidemic? International Journal of Obesity, 35(11), 1395-1403. [More Information]
- Arima, H., Barzi, F., Chalmers, J. (2011). Mortality patterns in hypertension. Journal of Hypertension, 29(SUPPL. 1), S3-S7. [More Information]
- Chalmers, J., Kengne, A. (2011). Predictive factors in assessing cardiovascular risk: learning from ADVANCE. Medicographia, 33(1), 47-51.
- Arima, H., Chalmers, J. (2011). PROGRESS: Prevention of recurrent stroke. Journal of Clinical Hypertension, 13(9), 693-702. [More Information]
- Hackam, D., Woodward, M., Newby, L., Bhatt, D., Shao, M., Smith, E., Donner, A., Muhammad, M., Douketis, J., Arima, H., Chalmers, J., MacMahon, S., et al (2011). Statins and Intracerebral Hemorrhage: Collaborative Systematic Review and Meta-analysis. Circulation, 124(20), 2233-2242. [More Information]
- Arima, H., Chalmers, J. (2011). Stroke: Blood pressure lowering in acute stroke-scant joy from SCAST. Nature Reviews Cardiology, 8(7), 366-368. [More Information]
- Czernichow, S., Zanchetti, A., Turnbull, F., Barzi, F., Ninomiya, T., Kengne, A., Heerspink, H., Perkovic, V., Huxley, R., Arima, H., Patel, A., Chalmers, J., Woodward, M., MacMahon, S., Neal, B. (2011). The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials. Journal of Hypertension, 29(1), 4-16. [More Information]
- Jardine, M., Ninomiya, T., Perkovic, V., Cass, A., Turnbull, F., Gallagher, M., Zoungas, S., Heerspink, H., Chalmers, J., Zanchetti, A. (2010). Aspirin is beneficial in hypertensive patients with chronic kidney disease a post-hoc subgroup analysis of a randomized controlled trial. Journal of the American College of Cardiology, 56(12), 956-965. [More Information]
- Lee, C., Stolk, R., Adler, A., Patel, A., Chalmers, J., Neal, B., Poulter, N., Harrap, S., Woodward, M., Marre, M., et al (2010). Association between alcohol consumption and diabetic retinopathy and visual acuity-the AdRem Study. Diabetic Medicine, 27(10), 1130-1137. [More Information]
- Heeley, E., Peiris, D., Patel, A., Cass, A., Weekes, A., Morgan, C., Anderson, C., Chalmers, J. (2010). Cardiovascular risk perception and evidence-practice gaps in Australian general practice (the AusHEART study). Medical Journal of Australia, 192(5), 254-259. [More Information]
- Glasziou, P., Clarke, P., Alexander, J., Rajmokan, M., Beller, E., Woodward, M., Chalmers, J., Poulter, N., Patel, A. (2010). Cost-effectiveness of lowering blood pressure with a fixed combination of perindopril and indapamide in type 2 diabetes mellitus: an ADVANCE trial-based analysis. Medical Journal of Australia, 193(6), 320-324. [More Information]
- Head, G., Mihailidou, A., Duggan, K., Beilin, L., Berry, N., Brown, M., Bune, A., Cowley, D., Chalmers, J., Howe, P., et al (2010). Definition of ambulatory blood pressure targets for diagnosis and treatment of hypertension in relation to clinic blood pressure: prospective cohort study. BMJ: British Medical Journal, 340(7751), 1-8. [More Information]
- Lambers Heerspink, H., Ninomiya, T., Perkovic, V., Woodward, M., Zoungas, S., Cass, A., Cooper, M., Grobbee, D., Mancia, G., Mogensen, C., Neal, B., Chalmers, J. (2010). Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease. European Heart Journal, 31(23), 2888-2896. [More Information]
- Anderson, C., Huang, Y., Arima, H., Heeley, E., Skulina, C., Parsons, M., Peng, B., Li, Q., Su, S., Tao, Q., Chalmers, J., et al (2010). Effects of Early Intensive Blood Pressure-Lowering Treatment on the Growth of Hematoma and Perihematomal Edema in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial(INTERACT). Stroke, 41(2), 307-312. [More Information]
- Neal, B., Jun, M., Foote, C., Lv, J., Patel, A., Nicholls, S., Grobbee, D., Cass, A., Chalmers, J., Perkovic, V. (2010). Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis. The Lancet, 375(9729), 1875-1884. [More Information]
- Arima, H., Tzourio, C., Anderson, C., Woodward, M., Bousser, M., MacMahon, S., Neal, B., Chalmers, J. (2010). Effects of Perindopril-Based Lowering of Blood Pressure on Intracerebral Hemorrhage Related to Amyloid Angiopathy. The PROGRESS Trial. Stroke, 41(2), 394-396. [More Information]
- Ninomiya, T., Zoungas, S., Neal, B., Woodward, M., Patel, A., Perkovic, V., Cass, A., Cooper, M., Grobbee, D., Hamet, P., Rodgers, A., MacMahon, S., Chalmers, J., et al (2010). Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial. Journal of Hypertension, 28(6), 1141-1149. [More Information]
- Batty, G., Li, Q., Czernichow, S., Neal, B., Zoungas, S., Huxley, R., Patel, A., de Galan, B., Woodward, M., Hamet, P., Chalmers, J., et al (2010). Erectile Dysfunction and Later Cardiovascular Disease in Men With Type 2 Diabetes: Prospective Cohort Study Based on the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation) Trial. Journal of the American College of Cardiology, 56(23), 1908-1913. [More Information]
- Patel, A., Neal, B., Chalmers, J. (2010). Event rates in trials of patients with type 2 diabetes. JAMA, 303(8), 732. [More Information]
- Clarke, P., Glasziou, P., Patel, A., Chalmers, J., Woodward, M., Harrap, S., Salomon, J. (2010). Event rates, hospital utilization, and costs associated with major complications of diabetes: a multicountry comparative analysis. PLoS Medicine, 7(2), e1000236-1-e1000236-10. [More Information]
- Brugts, J., Isaacs, A., Boersma, E., van Duijn, C., Uitterlinden, A., Remme, W., Bertrand, M., Ninomiya, T., Ceconi, C., Chalmers, J., MacMahon, S., et al (2010). Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease. European Heart Journal, 31(15), 1854-1864. [More Information]
- Czernichow, S., Ninomiya, T., Huxley, R., Kengne, A., Batty, G., Grobbee, D., Woodward, M., Neal, B., Chalmers, J. (2010). Impact of Blood Pressure Lowering on Cardiovascular Outcomes in Normal Weight, Overweight, and Obese Individuals: The Perindopril Protection Against Recurrent Stroke Study Trial. Hypertension, 55(5), 1193-1198. [More Information]
- Chalmers, J., Arima, H. (2010). Importance of Blood Pressure Lowering in Type 2 Diabetes: Focus on ADVANCE. Journal of Cardiovascular Pharmacology, 55(4), 340-347. [More Information]
- Chalmers, J., Harrap, S., Narkiewicz, K., Poulter, N., Redon, J., Zanchetti, A., Mancia, G. (2010). Issues in the development of new combinations of blood pressure lowering drugs. Journal of Hypertension, 28(12), 2494-2496. [More Information]
- Arima, H., Anderson, C., Wang, J., Huang, Y., Heeley, E., Neal, B., Woodward, M., Skulina, C., Parsons, M., Peng, B., Chalmers, J., et al (2010). Lower Treatment Blood Pressure Is Associated With Greatest Reduction in Hematoma Growth After Acute Intracerebral Hemorrhage. Hypertension, 56, 852-858. [More Information]
- Li, Q., Chalmers, J., Czernichow, S., Neal, B., Taylor, B., Zoungas, S., Poulter, N., Woodward, M., Patel, A., de Galan, B., et al (2010). Oral disease and subsequent cardiovascular disease in people with type 2 diabetes: a prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial. Diabetologia, 53(11), 2320-2327. [More Information]
- Arima, H., Anderson, C., Omae, T., Liu, L., Tzourio, C., Woodward, M., MacMahon, S., Neal, B., Rodgers, A., Chalmers, J. (2010). Perindopril-based blood pressure lowering reduces major vascular events in Asian and Western participants with cerebrovascular disease: the PROGRESS trial. Journal of Hypertension, 28(2), 395-400. [More Information]
- Zoungas, S., Patel, A., Chalmers, J., de Galan, B., Li, Q., Billot, L., Woodward, M., Ninomiya, T., Neal, B., MacMahon, S., Kengne, A., et al (2010). Severe hypoglycemia and risks of vascular events and death. New England Journal of Medicine, 363(15), 1410-1418. [More Information]
- Zoungas, S., Chalmers, J., Kengne, A., Pillai, A., Billot, L., de Galan, B., Marre, M., Neal, B., Harrap, S., Poulter, N., Patel, A. (2010). The efficacy of lowering glycated haemoglobin with a gliclazide modified release-based intensive glucose lowering regimen in the ADVANCE trial. Diabetes Research and Clinical Practice, 89(2), 126-133. [More Information]
- Kengne, A., Patel, A., Colagiuri, S., Heller, S., Hamet, P., Marre, M., Pan, C., Zoungas, S., Grobbee, D., Neal, B., Chalmers, J., Woodward, M. (2010). The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax. Diabetologia, 53(5), 821-831. [More Information]
- Delcourt, C., Huang, Y., Wang, J., Heeley, E., Lindley, R., Stapf, C., Tzourio, C., Arima, H., Parsons, M., Sun, J., Neal, B., Chalmers, J., Anderson, C. (2010). The second (main) phase of an open, randomised, multicentre study to investigate the effectiveness of an intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT2). International Journal of Stroke, 5(2), 110-116. [More Information]
- Patel, A., Chalmers, J., MacMahon, S., Neal, B. (2009). ADVANCE: Blood Pressure Lowering in Diabetes (Letter to the Editor). Journal of Clinical Hypertension, 11(2), 108-108. [More Information]
- Ninomiya, T., Perkovic, V., de Galan, B., Zoungas, S., Pillai, A., Jardine, M., Patel, A., Cass, A., Neal, B., Poulter, N., Woodward, M., MacMahon, S., Chalmers, J., et al (2009). Albuminuria and Kidney Function Independently Predict Cardiovascular and Renal Outcomes in Diabetes. Journal of the American Society of Nephrology, 20(8), 1813-1821. [More Information]
- Tavakoli, M., Pumford, N., Woodward, M., Doney, A., Chalmers, J., MacMahon, S., MacWalter, R. (2009). An economic evaluation of a perindopril-based blood pressure lowering regimen for patients who have suffered a cerebrovascular event. The European Journal of Health Economics, 10, 111-119. [More Information]
- Kengne, A., Czernichow, S., Huxley, R., Grobbee, D., Woodward, M., Neal, B., Zoungas, S., Cooper, M., Glasziou, P., Hamat, P., Chalmers, J., et al (2009). Blood Pressure Variables and Cardiovascular Risk: New Findings From ADVANCE. Hypertension, 54(2), 399-404. [More Information]
- Zoungas, S., Chalmers, J., Patel, A. (2009). Cardiovascular Risk in Type 2 Diabetes - Reflecting on the ADVANCE Study. European Endocrinology, 5(1), 42-46.
- Zoungas, S., Chalmers, J., Patel, A. (2009). Cardiovascular risk in Type 2 diabetes - reflecting on the ADVANCE study. U S Endocrinology, 5(1), 95-99.
- Zoungas, S., Chalmers, J., Patel, A. (2009). Cardiovascular Risk in Type 2 Diabetes?Reflecting on the ADVANCE Study. U S Endocrinology, 5(1), 95-99.
- de Galan, B., Zoungas, S., Chalmers, J., Anderson, C., Dufouil, C., Pillai, A., Cooper, M., Grobbee, D., Hackett, M., Hamet, P., MacMahon, S., Neal, B., Patel, A., Woodward, M., et al (2009). Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial. Diabetologia, 52(11), 2328-2336. [More Information]
- Ninomiya, T., Donnan, G., Anderson, N., Bladin, C., Chambers, B., Gordon, G., Sharpe, N., Chalmers, J., Woodward, M., Neal, B. (2009). Effects of the end point adjudication process on the results of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS). Stroke, 40(6), 2111-2115. [More Information]
- Czernichow, S., Lee, C., Barzi, F., Greenfield, J., Baur, L., Chalmers, J., Woodward, M., Huxley, R. (2009). Efficacy of weight loss drugs on obesity and cardiovascular risk factors in obese adolescents: a meta-analysis of randomized controlled trials. Obesity Reviews, Online, 1-9. [More Information]
- Turnbull, F., Abraira, C., Anderson, R., Byington, R., Chalmers, J., Duckworth, W., Evans, G., Gerstein, H., Holman, R., Moritz, T., Neal, B., Ninomiya, T., Patel, A., Woodward, M., et al (2009). Intensive glucose control and macrovascular outcomes in type 2 diabetes. Diabetologia, 52(11), 2288-2298. [More Information]
- de Galan, B., Perkovic, V., Ninomiya, T., Pillai, A., Patel, A., Cass, A., Neal, B., Poulter, N., Harrap, S., Mogensen, C., Woodward, M., MacMahon, S., Chalmers, J., et al (2009). Lowering Blood Pressure Reduces Renal Events in Type 2 Diabetes. Journal of the American Society of Nephrology, 20(4), 883-892. [More Information]
- Chalmers, J., Arima, H. (2009). Management of hypertension: evidence from the Blood Pressure Lowering Treatment Trialists' Collaboration and from major clinical trials. Polskie Archiwum Medycyny Wewnetrznej, 119(6), 373-380. [More Information]
- Ninomiya, T., Perkovic, V., Verdon, C., Barzi, F., Cass, A., Gallagher, M., Jardine, M., Anderson, C., Chalmers, J., Craig, J., Huxley, R. (2009). Proteinuria and Stroke: A Meta-analysis of Cohort Studies. American Journal of Kidney Diseases, 53(3), 417-425. [More Information]
- Du, X., Ninomiya, T., de Galan, B., Abadir, E., Chalmers, J., Pillai, A., Woodward, M., Cooper, M., Harrap, S., Hamet, P., Patel, A., et al (2009). Risks of cardiovascular events and effects of routine blood pressure lowering among patients with type 2 diabetes and atrial fibrillation: results of the ADVANCE study. European Heart Journal, 30, 1128-1135. [More Information]
- Joshi, R., de Galan, B., Chalmers, J., Perkovic, V., Patel, A. (2009). Routine blood pressure lowering and intense glucose control in patients with type 2 diabetes: results from the ADVANCE trial. Expert Review of Endocrinology & Metabolism, 4(2), 111-118. [More Information]
- Dufouil, C., Godin, O., Chalmers, J., Coskun, O., MacMahon, S., Tzourio-Mazoyer, N., Bousser, M., Anderson, C., Mazoyer, B., Tzourio, C. (2009). Severe cerebral white matter hyperintensities predict severe cognitive decline in patients with cerebrovascular disease history. Stroke, 40(6), 2219-2221. [More Information]
- Arima, H., Wang, J., Huang, Y., Heeley, E., Skulina, C., Parsons, M., Peng, B., Li, Q., Su, S., Tao, Q., Chalmers, J., Anderson, C., et al (2009). Significance of perihematomal edema in acute intracerebral hemorrhage: The INTERACT trial. Neurology, 73(23), 1963-1968. [More Information]
- Zoungas, S., de Galan, B., Ninomiya, T., Grobbee, D., Hamet, P., Heller, S., MacMahon, S., Marre, M., Neal, B., Patel, A., Woodward, M., Chalmers, J. (2009). The combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes; new results from ADVANCE. Diabetes Care, 32(11), 2068-2074. [More Information]
- Brugts, J., Ninomiya, T., Boersma, E., Remme, W., Bertrand, M., Ferrari, R., Fox, K., MacMahon, S., Chalmers, J., Simoons, M. (2009). The consistency of the treatment effect of an ACE-inhibitor based treatment regimen in patients with vascular disease or high risk of vascular disease: a combined analysis of individual data of ADVANCE, EUROPA, and PROGRESS trials. European Heart Journal, 30(11), 1385-1394. [More Information]
- Chalmers, J., Joshi, R., Patel, A. (2008). Advances in reducing the burden of ascular disease in type 2 diabetes. Clinical and Experimental Pharmacology and Physiology, 35, 434-437. [More Information]
- Chockalingham, A., Chalmers, J., Whitworth, J., Erdine, S., Mancia, G., Mendis, S., Heagerty, A. (2008). Antalya statement of the International Society of Hypertension on the prevention of blood pressure-related diseases. Journal of Hypertension, 26, 2255-2258. [More Information]
- Tzourio, C., Arima, H., Harrap, S., Anderson, C., Godin, O., Woodward, M., Neal, B., Bousser, M., Chalmers, J., Cambien, F., MacMahon, S. (2008). APOE genotype, ethnicity, and the risk of cerebral hemorrhage. Neurology, 70(16 (Part 1-2)), 1322-1328. [More Information]
- Welsh, P., Lowe, G., Chalmers, J., Campbell, D., Rumley, A., Neal, B., MacMahon, S., Woodward, M. (2008). Associations of Proinflammatory Cytokines With the Risk of Recurrent Stroke. Stroke, 39, 2226-2230. [More Information]
- Chalmers, J., Joshi, R., Kengne, A., MacMahon, S. (2008). Blood pressure lowering with fixed combination perindopril-indapamide: key findings from ADVANCE. Journal of Hypertension, 26(suppl 2), S11-S15. [More Information]
- Turnbull, F., Woodward, M., Neal, B., Barzi, F., Ninomiya, T., Chalmers, J., Perkovic, V., Li, N., MacMahon, S. (2008). Do men and women respond differently to blood pressure-lowering treatment? Results of prospectively designed overviews of randomized trials. European Heart Journal, 29(21), 2669-2680. [More Information]
- Turnbull, F., Neal, B., Ninomiya, T., Algert, C., Arima, H., Barzi, F., Bulpitt, C., Chalmers, J., Fagard, R., Gleason, A., Heritier, S., Perkovic, V., Woodward, M., MacMahon, S., et al (2008). Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials. BMJ: British Medical Journal, 336(6753), 1121-1123. [More Information]
- Chalmers, J., Joshi, R., Kengne, A., Ninomiya, T., Bi, Y., Bompoint, S., Billot, L., Patel, A. (2008). Efficacy and safety of fixed combination of perindopril and indapamide in type 2 diabetes: results from ADVANCE in context of available evidence. Journal of Hypertension, 26(Suppl 3), S21-S27. [More Information]
- Patel, A., MacMahon, S., Chalmers, J., Neal, B., Billot, L., Woodward, M., Marre, M., Cooper, M., Glasziou, P., Grobbee, D., Joshi, R., et al (2008). Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. New England Journal of Medicine, 358(24), 2560-2572. [More Information]
- Anderson, C., Huang, Y., Wang, J., Arima, H., Neal, B., Peng, B., Heeley, E., Skulina, C., Parsons, M., Jong, S., Heritier, S., Chalmers, J., et al (2008). Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. The Lancet Neurology, 7(5), 391-399. [More Information]
- Patel, A., MacMahon, S., Chalmers, J. (2008). Intensive glucose control in type 2 diabetes - the author's reply. New England Journal of Medicine, 359, 1519-21.
- Chalmers, J., Zhang, J. (2008). Introduction: Advances in the prevention of cardiovascular disease in patients with diabetes. Journal of Hypertension, 26, S1-2. [More Information]
- Ninomiya, T., Perkovic, V., Gallagher, M., Jardine, M., Cass, A., Arima, H., Anderson, C., Neal, B., Woodward, M., Omae, T., MacMahon, S., Chalmers, J. (2008). Lower blood pressure and risk of recurrent stroke in patients with chronic kidney disease: PROGRESS trial. Kidney International, 73(8), 963-970. [More Information]
- Wu, Y., Huxley, R., Li, L., Anna, V., Xie, G., Yao, C., Woodward, M., Li, X., Chalmers, J., Gao, R., et al (2008). Prevalence, Awareness, Treatment, and Control of Hypertension in China: Data from the China National Nutrition and Health Survey 2002. Circulation, 118(25), 2679-2686. [More Information]
- Patel, A., MacMahon, S., Billot, L., Chalmers, J. (2008). The ADVANCE Trial - the author's reply. The Lancet, 371(9606), 25-26.
- Perkovic, V., Verdon, C., Ninomiya, T., Barzi, F., Cass, A., Patel, A., Jardine, M., Gallagher, M., Turnbull, F., Chalmers, J., Craig, J., Huxley, R. (2008). The relationship between proteinuria and coronary risk: a systematic review and meta-analysis. PLoS Medicine, 5(10), 1486-1495. [More Information]
- Chalmers, J., Cooper, M. (2008). UKPDS and the legacy effect. New England Journal of Medicine, 359(15), 1618-20. [More Information]
- Turnbull, F., Neal, B., Pfeffer, M., Kostis, J., Algert, C., Woodward, M., Chalmers, J., Zanchetti, A., MacMahon, S. (2007). Blood pressure-dependent and independent effects of agents that inhibit the renin-angiotensin system. Journal of Hypertension, 25(5), 951-958. [More Information]
- Perkovic, V., Ninomiya, T., Arima, H., Jardine, M., Cass, A., Neal, B., MacMahon, S., Chalmers, J. (2007). Chronic Kidney Disease, Cardiovascular Events, and The Effects Of Perindopril-Based Blood Pressure Lowering: Data From The PROGRESS Study. Journal of the American Society of Nephrology, 18(10), 2766-2772. [More Information]
- Patel, A., MacMahon, S., Chalmers, J., Neal, B., Woodward, M., Billot, L., Harrap, S., Poulter, N., Marre, M., Cooper, M., et al (2007). Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. The Lancet, 370(9590), 829-840. [More Information]
- Chalmers, J., Zhang, J. (2007). Introduction. Journal of Hypertension, 25, S1-2. [More Information]
- Campbell, D., Neal, B., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Patel, A., MacMahon, S., Woodward, M. (2007). Low-density lipoprotein particles and risk of intracerebral haemorrhage in subjects with cerebrovascular disease. European Journal of Cardiovascular Prevention and Rehabilitation, 14(3), 413-418. [More Information]
- Chalmers, J., Kengne, A., Joshi, R., Perkovic, V., Patel, A. (2007). New insights from ADVANCE. Journal of Hypertension, 25(Suppl. 1), S23-S30. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2007). Perindopril-based blood pressure-lowering therapy reduces amino-terminal-pro-B-type natriuretic peptide in subjects with cerebrovascular disease. Journal of Hypertension, 25(3), 699-705. [More Information]
- Chalmers, J., Perkovic, V., Joshi, R., Patel, A. (2006). ADVANCE: breaking new ground in type 2 diabetes. Journal of Hypertension, 24(Supplement 5), S22-S28. [More Information]
- Perkovic, V., Joshi, R., Patel, A., Bompoint, S., Chalmers, J., Neal, B., MacMahon, S., Glasziou, P., Woodward, M., Cooper, M., et al (2006). ADVANCE: Lessons from the run-in phase of a large study in type 2 diabetes. Blood Pressure, 15(6), 340-346. [More Information]
- Chalmers, J. (2006). Blood pressure and stroke: a continuing debate. Journal of Hypertension, 24(7), 1249-51. [More Information]
- Gallagher, M., Perkovic, V., Chalmers, J. (2006). Diuretics: A modern day treatment option? (Review Article). Nephrology, 11(5), 419-427. [More Information]
- Arima, H., Chalmers, J., Woodward, M., Anderson, C., Rodgers, A., Davis, S., MacMahon, S., Neal, B., PROGRESS, C. (2006). Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial. Journal of Hypertension, 24(6), 1201-1208. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Patel, A., MacMahon, S. (2006). Perindopril-based blood pressure-lowering therapy reduces amino-terminal-pro-B-type natriuretic peptide levels in subjects with cerebrovascular disease. European Heart Journal, 27(Suppl 1), 781.
- Arima, H., Tzourio, C., Butcher, K., Anderson, C., Bousser, M., Lees, K., Reid, J., Omae, T., Woodward, M., MacMahon, S., Chalmers, J. (2006). Prior Events Predict Cerebrovascular and Coronary Outcomes in the PROGRESS Trial. Stroke, 37(6), 1497-1502. [More Information]
- Arima, H., Chalmers, J. (2006). Secondary prevention of stroke by blood pressure-lowering treatment. Current Hypertension Reports, 8(4), 317-323. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2006). Soluble vascular cell adhesion molecule 1 and N-terminal pro-B-type natriuretic peptide in predicting ischemic stroke in patients with cerebrovascular disease. JAMA Neurology, 63(1), 60-65. [More Information]
- Chalmers, J., MacMahon, S., Colman, S., Heller, S., Neal, B., Pan, C., Patel, A., Woodward, M., Cooper, M., Adams, M., Fulcher, G., Mitchell, P., Pollock, C., Watson, J., et al (2005). ADVANCE - Action in Diabetes and Vascular Disease: patient recruitment and characteristics of the study population at baseline. Diabetic Medicine, 22(7), 882-888. [More Information]
- Patel, A., Chalmers, J., Poulter, N. (2005). ADVANCE: action in diabetes and vascular disease. Journal of Human Hypertension, 19(Suppl 1), S27-S32. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Neal, B., Patel, A., MacMahon, S. (2005). Amino-terminal pro-B-type natriuretic peptide (NT-proBNP): a risk factor for most seasons. European Heart Journal, 26(Suppl 1), 257.
- Woodward, M., Lowe, G., Campbell, D., Colman, S., Rumley, A., Chalmers, J., Neal, B., Patel, A., Jenkins, A., Kemp, B., MacMahon, S. (2005). Associations of Inflammatory and Hemostatic Variables With the Risk of Recurrent Stroke. Stroke, 36(10), 2143-2147. [More Information]
- Chalmers, J. (2005). Blood pressure in acute stroke: in search of evidence. Journal of Hypertension, 23(2), 277-8. [More Information]
- Dufouil, C., Chalmers, J., Coskun, O., Besancon, V., Bousser, M., Guillon, P., MacMahon, S., Mazoyer, B., Neal, B., Woodward, M., Tzourio, C., et al (2005). Effects of Blood Pressure Lowering on Cerebral White Matter Hyperintensities in Patients With Stroke: The PROGRESS (Perindopril Protection Against Recurrent Stroke Study) Magnetic Resonance Imaging Substudy. Circulation, 112(11), 1644-1650. [More Information]
- Turnbull, F., Neal, B., Algert, C., Chalmers, J., Chapman, N., Cutler, J., Woodward, M., MacMahon, S. (2005). Effects of Different Blood Pressure-Lowering Regimens on Major Cardiovascular Events in Individuals With and Without Diabetes Mellitus: Results of Prospectively Designed Overviews of Randomized Trials. Archives of Internal Medicine, 165(12), 1410-1419. [More Information]
- Arima, H., Hart, R., Colman, S., Chalmers, J., Anderson, C., Rodgers, A., Woodward, M., MacMahon, S., Neal, B. (2005). Perindopril-Based Blood Pressure–Lowering Reduces Major Vascular Events in Patients With Atrial Fibrillation and Prior Stroke or Transient Ischemic Attack. Stroke, 36(10), 2164-2169. [More Information]
- Patel, A., Woodward, M., Campbell, D., Sullivan, D., Colman, S., Chalmers, J., Neal, B., MacMahon, S. (2005). Plasma lipids predict myocardial infarction, but not stroke, in patients with established cerebrovascular disease. European Heart Journal, 26(18), 1910-1915. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2005). Prediction of Heart Failure by Amino Terminal-pro-B-Type Natriuretic Peptide and C-Reactive Protein in Subjects With Cerebrovascular Disease. Hypertension, 45(1), 69-74. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2005). Prediction of Myocardial Infarction by N-Terminal-Pro-B-Type Natriuretic Peptide, C-Reactive Protein, and Renin in Subjects With Cerebrovascular Disease. Circulation, 112(1), 110-116. [More Information]
- MacMahon, S., Neal, B., Rodgers, A., Chalmers, J. (2004). Commentary: The PROGRESS trial three years later: time for more action, less distraction. BMJ: British Medical Journal, 329(7472), 970-971. [More Information]
- Chalmers, J. (2004). Comparison Of Various Blood Pressure Lowering Treatments on the Primary Prevention of Cardiovascular Outcomes in Recent Randomised Clinical Trials. Clinical and Experimental Hypertension, 26(7-8), 709-719. [More Information]
- Chapman, N., Huxley, R., Anderson, C., Bousser, M., Chalmers, J., Colman, S., Davis, S., Donnan, G., MacMahon, S., Neal, B., Woodward, M., et al (2004). Effects of a Perindopril-Based Blood Pressure–Lowering Regimen on the Risk of Recurrent Stroke According to Stroke Subtype and Medical History: The PROGRESS Trial. Stroke, 35(1), 116-121. [More Information]
- Ohkubo, T., Chapman, N., Neal, B., Woodward, M., Omae, T., Chalmers, J., Anderson, C. (2004). Effects of an Angiotensin-converting Enzyme Inhibitor-based Regimen on Pneumonia Risk. American Journal of Respiratory and Critical Care Medicine, 169(9), 1041-1045.
- Hasegawa, Y., Yamaguchi, T., Omae, T., Woodward, M., Chalmers, J. (2004). Effects of Perindopril-Based Blood Pressure Lowering and of Patient Characteristics on the Progression of Silent Brain Infarct: The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) CT Substudy in Japan. Hypertension Research, 27(3), 147-156. [More Information]
- Berthet, K., Neal, B., MacMahon, S., Bousser, M., Colman, S., Woodward, M., Chalmers, J. (2004). Lacunar stroke in PROGRESS study. European Journal of Neurology, 11(Suppl 2), 29.
- Chalmers, J. (2004). Nouvelles Strategies Pour Le Controle De L'Hypertension: Preuves Supplementaries En Faveur Des Associations Faiblement Dosees. (New Strategies For Hypertension Control : More Evidence For Low-Dose Combination Therapy). American Journal of Cardiovascular Drugs, 4(Supplement 1), 37-42. [More Information]
- Rodgers, A., Chapman, N., Woodward, M., Liu, L., Colman, S., Lee, A., Chalmers, J., MacMahon, S., Anderson, C. (2004). Perindopril-based blood pressure lowering in individuals with cerebrovascular disease: consistency of benefits by age, sex and region. Journal of Hypertension, 22(3), 653-659. [More Information]
- Berthet, K., Neal, B., Chalmers, J., MacMahon, S., Bousser, M., Colman, S., Woodward, M., Anderson, C. (2004). Reductions in the Risks of Recurrent Stroke in Patients With and Without Diabetes: The PROGRESS Trial. Blood Pressure, 13(1), 7-13. [More Information]
- MacMahon, S., Chalmers, J. (2003). Blood pressure lowering and ACE inhibition for the avoidance of cardiac and cerebral events. European Heart Journal, 24(5), 391-393. [More Information]
- Patel, A., Chalmers, J., Chaturvedi, V., Currie, R., Monaghan, H., Neal, B. (2003). Diabetes and vascular disease: a new international trial. Asian Cardiovascular and Thoracic Annals, 11(2), 180-184. [More Information]
- Chaturvedi, V., Patel, A., Chalmers, J., Chapman, N., Hansson, L., MacMahon, S., Mancia, G., Neal, B., Reid, J., Sharpe, N., Woodward, M., Anderson, C., et al (2003). Effects of a perindopril-based blood pressure lowering regimen on cardiac outcomes among patients with cerebrovascular disease. European Heart Journal, 24(5), 475-484. [More Information]
- Fransen, M., Anderson, C., Chalmers, J., Chapman, N., Davis, S., MacMahon, S., Neal, B., Sega, R., Terent, A., Tzourio, C., Woodward, M. (2003). Effects of a Perindopril-Based Blood Pressure-Lowering Regimen on Disability and Dependency in 6105 Patients With Cerebrovascular Disease: A Randomized Controlled Trial. Stroke, 34(10), 2333-2338. [More Information]
- Tzourio, C., Anderson, C., Chapman, N., Woodward, M., Neal, B., MacMahon, S., Chalmers, J., Lindley, R. (2003). Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Archives of Internal Medicine, 163(9), 1069-1075. [More Information]
- Turnbull, F., Neal, B., Algert, C., Chalmers, J., Woodward, M., MacMahon, S. (2003). Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomized trials. The Lancet, 362(9395), 1527-1535. [More Information]
- Chalmers, J. (2003). Etude ADVANCE: objectifs, protocole et etat actuel. Drugs, 63(Special Issue 1), 39-44.
- Chalmers, J., Todd, A., Chapman, N., Beilin, L., Davis, S., Donnan, G., Frommer, M., Huxley, R., Lenfant, C., MacMahon, S., et al (2003). International Society of hypertension (ISH): Statement on blood pressure lowering and stroke prevention. Journal of Hypertension, 21(4), 651-663. [More Information]
- Bath, P., Chalmers, J., Powers, W., Lawrie, B., Davis, S., Lenfant, C., Mancia, G., Neal, B., Whitworth, J., Zanchetti, A. (2003). International society of hypertension (ISH): Statement on the management of blood pressure in acute stroke. Journal of Hypertension, 21(4), 665-672. [More Information]
- Chalmers, J., Arnolda, L. (2003). Lowering blood pressure in 2003. Medical Journal of Australia, 179(6), 306-312.
- Chalmers, J., MacMahon, S. (2003). Perindopril Protection Against Recurrent Stroke Study (PROGRESS) : Interpretation and implementation. Journal of Hypertension, 21(Suppl 5), S9-S14.
- Harrap, S., Tzourio, C., Cambien, F., Poirier, O., Raoux, S., Chalmers, J., Chapman, N., Colman, S., Leguennec, S., MacMahon, S., Neal, B., Ohkubo, T., Woodward, M., Anderson, C. (2003). The ACE Gene I/D Polymorphism Is Not Associated With the Blood Pressure and Cardiovascular Benefits of ACE Inhibition. Hypertension, 42(3), 297-303. [More Information]
- Chapman, N., Chalmers, J. (2003). The prevention of secondary stroke, cardiac outcomes and cognitive decline in patients with cerebrovascular disease: The PROGRESS Trial. Seminars In Cerebrovascualr Diseases and Stroke, 3(3), 171-180.
- Chalmers, J. (2003). Trials on blood pressure-lowering and secondary stroke prevention. American Journal of Cardiology, 91(10A), 3G-8G. [More Information]
- Chalmers, J. (2002). Enhancing risk stratification in hypertensive subjects: how far should we go in routine screening for target organ damage? Journal of Hypertension, 20(7), 1255-1257. [More Information]
- Freedman, B., Brieger, D., Celermajer, D., Chalmers, J., Tofler, G., Campbell, T., Feneley, M., Marwick, T., Muller, D., Tonkin, A. (2002). Global cardiology comes to Australia: 14th World Congress of Cardiology, Sydney, 5-9 May 2002. Medical Journal of Australia, 177(9), 473-475. [More Information]
- Chalmers, J. (2002). The ABCD of anti-hypertensive therapy? Journal of Hypertension, 20(4), 615-616. [More Information]
- Chalmers, J. (2002). Treating Hypertension or Lowering Blood Pressure? Extending the Concept. Blood Pressure, 11(2), 68-70. [More Information]
- Chalmers, J., Whitworth, J. (2001). A half-century of Australian health and medical research. Medical Journal of Australia, 174, 29-32.
- Neal, B., Chapman, J., Chalmers, J., MacMahon, S., Girgis, S., Patel, A. (2001). Blood pressure and the vascular complications of diabetes. Medicographia, 23(3), 214-219.
- Chalmers, J., Neal, B., Chapman, J., MacMahon, S., Patel, A., Girgis, S. (2001). Blood pressure lowering in diabetes: a brief review of the current evidence and description of a new trial. Clinical and Experimental Pharmacology and Physiology, 28, 1108-1111. [More Information]
- Goodchild, A., Sun, Q., Chalmers, J., Pilowsky, P., Llewellyn-Smith, I., Cunningham, A. (2001). Calbindin-Ummunoreactive neurons in the reticular formation of the rat brainstem: catecholamine content and spinal projections. Journal of Comparative Neurology, 424, 547-562.
- Chalmers, J., Chapman, J. (2001). Challenges for the prevention of primary and secondary stroke: the importance of lowering blood pressure and total cardiovascular risk. Blood Pressure, 10, 344-351.
- Goodchild, A., Chalmers, J., Pilowsky, P., Phillips, J., Dubey, R., Sesiashvili, E., Takeda, M., Lipski,, J. (2001). Differential expression of catecholamine biosynthetic enzymes in the rat ventrolateral medulla. Journal of Comparative Neurology, 431, 20-34. [More Information]
- Chalmers, J. (2001). Ongoing trials of angiotensin-converting enzyme inhibition: what they can tell us. American Journal of Hypertension, 14.
- Chalmers, J., Chapman, J. (2001). Progress in reducing the burden of stroke. Clinical and Experimental Pharmacology and Physiology, 28, 1091-1095. [More Information]
- MacMahon, S., Neal, B., Woodward, M., Chalmers, J., Tzourio, C., Rodgers, A., Cutler, J., Ohkubo,, T., Lindley, R., Anderson, C. (2001). Randomised trail of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. The Lancet, 358, 1033-1041. [More Information]
- Chalmers, J., MacMahon, S., Neal, B., Girgis, S., Patel, A. (2001). Rationale and design of the ADVANCE study: a randomised trial of blood pressure lowering and intensive glucose control in high-risk individuals with type 2 diabetes mellitus. Journal of Hypertension, 19 (suppl 4).
- MacMahon, S., Rodgers, A., Neal, B., Woodward, M., Chalmers, J. (2001). REPLY: The lowering of blood pressure after stroke. The Lancet, 358(9297), 1994-1995.
- Chalmers, J., MacMahon, S., Neal, B., Ferrannini, E., Girgis, S., Patel, A. (2001). Study rationale and design of ADVANCE: Action in diabetes and vascular disease - preterax and diamicron MR controlled evaluation. Diabetologia, 44, 1118-1120.
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Conferences
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2008). Can NT-proBNP Monitoring Help Prevent Cardiovascular Disease? 13th World Congress on Heart Disease, Italy: Medimond International Proceedings.
Report
- Carey-Hazell, K., Boyden, A., Rooney, E., Chalmers, J., Jennings, G., Levi, C., Mathew, T., Tonkin, A., Beilby, J., Lowe, M., Lindley, R. (2005). National Health Priority Action Council (NHPAC) (2006), National Service Improvement Framework for Heart, Stroke and Vascular Disease.
- Ward, M., Bishop, J., Theile, D., Chalmers, J., Cass, A. (2003). Options for Clinical Services.
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2024
- Wang, N., Woodward, M., Chalmers, J., Harris, K., Poulter, N., Mancia, G., Harrap, S., Hamet, P., Grobbee, D., Marre, M. (2024). Combination blood pressure lowering therapy in patients with type 2 diabetes: messages from the ADVANCE trial. Journal of Hypertension, , 10.1097/HJH.0000000000003855. [More Information]
- Neuen, B., Jun, M., Wick, J., Kotwal, S., Badve, S., Jardine, M., Gallagher, M., Chalmers, J., Nallaiah, K., Perkovic, V., et al (2024). Estimating the population-level impacts of improved uptake of SGLT2 inhibitors in patients with chronic kidney disease: a cross-sectional observational study using routinely collected Australian primary care data. The Lancet Regional Health. Western Pacific, 43. [More Information]
- Chen, C., Robinson, T., Lindley, R., Arima, H., Chalmers, J., Li, G., Chen, X., Anderson, C., Song, L., Ren, X., et al (2024). Intensive Blood Pressure Lowering and Renal Function in Ischemic Stroke Patients: Secondary Analysis of the ENCHANTED Trial. Cerebrovascular Diseases. [More Information]
- You, S., Arima, H., Chen, X., Liu, C., Lindley, I., Robinson, T., Anderson, C., Chalmers, J., Zheng, D., Yoshimura, S., et al (2024). Optimum Baseline Clinical Severity Scale Cut Points for Prognosticating Intracerebral Hemorrhage: INTERACT Studies. Stroke, 55(1), 139-145. [More Information]
- Han, Q., Chen, C., Delcourt, C., Zhou, Z., Cao, Y., Liu, C., Zheng, D., Arima, H., Robinson, T., Chen, X., Lindley, R., et al (2024). Predictors of Early versus Delayed Neurological Deterioration after Thrombolysis for Ischemic Stroke. Cerebrovascular Diseases. [More Information]
- Jun, M., Nallaiah, K., Jardine, M., Perkovic, V., Gallagher, M., Ronksley, P., Wick, J., Neuen, B., Kotwal, S., Badve, S., et al (2024). The Prevalence of CKD in Australian Primary Care: Analysis of a National General Practice Dataset. Kidney International Reports, 9(2), 312-322. [More Information]
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2023
- Inker, L., Collier, W., Greene, T., Miao, S., Chaudhari, J., Appel, G., Badve, S., Caravaca-Fontán, F., Del Vecchio, L., Floege, J., et al (2023). A meta-analysis of GFR slope as a surrogate endpoint for kidney failure. Nature Medicine, 29(7), 1867-1876. [More Information]
- Wang, N., Harris, K., Woodward, M., Harrap, S., Mancia, G., Poulter, N., Chalmers, J., Rodgers, A. (2023). Clinical Utility of Short-Term Blood Pressure Measures to Inform Long-Term Blood Pressure Management. Hypertension, 80(3), 608-617. [More Information]
- Nolde, J., Atkins, E., Marschner, S., Hillis, G., Chalmers, J., Billot, L., Nelson, M., Reid, C., Hay, P., Burke, M., Usherwood, T., Chow, C., et al (2023). Effect of Initial Treatment With a Single Pill Containing Quadruple Combination of Quarter Doses of Blood Pressure Medicines Versus Standard Dose Monotherapy in Patients With Hypertension on Ambulatory Blood Pressure Indices: Results From the QUARTET Study. Circulation, 148(4), 375-377. [More Information]
- Chen, C., Ouyang, M., Ong, S., Zhang, L., Zhang, G., Delcourt, C., Mair, G., Liu, L., Billot, L., Li, Q., Lindley, R., et al (2023). Effects of intensive blood pressure lowering on cerebral ischaemia in thrombolysed patients: insights from the ENCHANTED trial. EClinicalMedicine, 57. [More Information]
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2022
- Wang, X., Minhas, J., Moullaali, T., Di Tanna, G., Lindley, R., Chen, X., Arima, H., Chen, G., Delcourt, C., Bath, P., et al (2022). Associations of Early Systolic Blood Pressure Control and Outcome after Thrombolysis-Eligible Acute Ischemic Stroke: Results from the ENCHANTED Study. Stroke, 29(2), 779-787. [More Information]
- Wang, N., Harris, K., Hamet, P., Harrap, S., Mancia, G., Poulter, N., Williams, B., Zoungas, S., Woodward, M., Chalmers, J., et al (2022). Cumulative Systolic Blood Pressure Load and Cardiovascular Risk in Patients With Diabetes. Journal of the American College of Cardiology, 80(12), 1147-1155. [More Information]
- Moullaali, T., Wang, X., Sandset, E., Woodhouse, L., Law, Z., Arima, H., Butcher, K., Chalmers, J., Delcourt, C., Edwards, L., et al (2022). Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data. Journal of Neurology, Neurosurgery and Psychiatry, 93(1), 6-13. [More Information]
- Nolde, J., Hillis, G., Atkins, E., Von Huben, A., Marschner, S., Chan, J., Reid, C., Nelson, M., Figtree, G., Chalmers, J., Usherwood, T., Chow, C., et al (2022). Impact of various night-time period definitions on nocturnal ambulatory blood pressure. Journal of Hypertension, 40(11), 2271-2279. [More Information]
- Gong, J., Harris, K., Tzourio, C., Harrap, S., Naismith, S., Anderson, C., Chalmers, J., Woodward, M. (2022). Sex differences in predictors for cognitive decline and dementia in people with stroke or transient ischemic attack in the PROGRESS trial. International Journal of Stroke, 17(8), 863-872. [More Information]
- Zhou, Z., Xia, C., Mair, G., Delcourt, C., Yoshimura, S., Liu, X., Chen, Z., Malavera, A., Carcel, C., Chen, X., Lindley, R., et al (2022). Thrombolysis outcomes according to arterial characteristics of acute ischemic stroke by alteplase dose and blood pressure target. International Journal of Stroke, 17(5), 566-575. [More Information]
- Anderson, C., Rodgers, A., De Silva, H., Martins, S., Klijn, C., Senanayake, B., Freed, R., Billot, L., Arima, H., Thang, N., Naismith, S., Lindley, R., Chow, C., et al (2022). Triple Therapy Prevention of Recurrent Intracerebral Disease Events Trial: Rationale, design and progress. International Journal of Stroke, 17(10), 1156-1162. [More Information]
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2021
- Song, L., Wang, X., Ouyang, M., Sun, L., Chen, X., Arima, H., Sandset, E., Delcourt, C., Wang, J., Chen, G., Lindley, R., Chalmers, J., Anderson, C., et al (2021). Associations of an Abnormal Physiological Score With Outcomes in Acute Intracerebral Hemorrhage: INTERACT2 Study. Stroke, 52(2), 722-725. [More Information]
- Wang, N., Harris, K., Chalmers, J., Harrap, S., Mancia, G., Marre, M., Poulter, N., Tzourio, C., Williams, B., Zoungas, S., et al (2021). Combination blood pressure lowering in the presence or absence of background statin and aspirin therapy: a combined analysis of PROGRESS and ADVANCE Trials. Journal of Hypertension, 39(8), 1689-1696. [More Information]
- Minhas, J., Wang, X., Lindley, R., Delcourt, C., Song, L., Woodward, M., Lee, T., Broderick, J., Pontes-Neto, O., Kim, J., et al (2021). Comparative effects of intensive-blood pressure versus standard-blood pressure-lowering treatment in patients with severe ischemic stroke in the ENCHANTED trial. Journal of Hypertension, 39(2), 280-285. [More Information]
- Oshima, M., Hara, A., Toyama, T., Jun, M., Pollock, C., Jardine, M., Harrap, S., Poulter, N., Cooper, M., Woodward, M., et al (2021). Comparison of Circulating Biomarkers in Predicting Diabetic Kidney Disease Progression With Autoantibodies to Erythropoietin Receptor. Kidney International Reports, 6(2), 284-295. [More Information]
- Chen, C., Wang, X., Chen, X., Ouyang, M., Sun, L., Arima, H., Robinson, T., Lindley, R., Chalmers, J., Li, G., Anderson, C., et al (2021). Disparities between Asian and Non-Asian Thrombolyzed Acute Ischemic Stroke Patients in the Enhanced Control of Hypertension and Thrombolysis Stroke Trial. Cerebrovascular Diseases, 50(5), 560-566. [More Information]
- Chow, C., Atkins, E., Hillis, G., Nelson, M., Reid, C., Schlaich, M., Hay, P., Rogers, K., Billot, L., Burke, M., Usherwood, T., et al (2021). Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial. The Lancet, 398(10305), 1043-1052. [More Information]
- Zhou, Z., Xia, C., Carcel, C., Yoshimura, S., Wang, X., Delcourt, C., Malavera, A., Chen, X., Mair, G., Woodward, M., et al (2021). Intensive versus guideline-recommended blood pressure reduction in acute lacunar stroke with intravenous thrombolysis therapy: The ENCHANTED trial. European Journal of Neurology, 28(3), 783-793. [More Information]
- Zhou, Z., Delcourt, C., Xia, C., Yoshimura, S., Carcel, C., Torii-Yoshimura, T., You, S., Malavera, A., Chen, X., Hackett, M., et al (2021). Low-Dose vs Standard-Dose Alteplase in Acute Lacunar Ischemic Stroke: The ENCHANTED Trial. Neurology, 96(11), e1512-e1526. [More Information]
- Tremblay, J., Haloui, M., Attaoua, R., Tahir, R., Hishmih, C., Harvey, F., Marois-Blanchet, F., Long, C., Simon, P., Santucci, L., Colagiuri, S., et al (2021). Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control. Diabetologia, 64(9), 2012-2025. [More Information]
- Chen, C., Song, L., Yang, J., Lindley, R., Robinson, T., Arima, H., Chalmers, J., Anderson, C., Wang, X. (2021). Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials. Frontiers in Neurology, 12, 687862. [More Information]
- Sun, L., Song, L., Yang, J., Lindley, R., Robinson, T., Lavados, P., Delcourt, C., Arima, H., Ovbiagele, B., Chalmers, J., et al (2021). Smoking influences outcome in patients who had thrombolysed ischaemic stroke: The ENCHANTED study. Stroke and Vascular Neurology, 6(3), 395-401. [More Information]
- Woodhouse, L., Montgomery, A., Mant, J., Davis, B., Algra, A., Mas, J., Staessen, J., Thijs, L., Tonkin, A., Kirby, A., et al (2021). Statistical reanalysis of vascular event outcomes in primary and secondary vascular prevention trials. BMC Medical Research Methodology, 21(1), 218. [More Information]
- Huang, L., Neal, B., Wu, J., Huang, Y., Marklund, M., Campbell, N., He, F., Yoshimura, S., Chalmers, J., Trieu, K. (2021). The impact of baseline potassium intake on the dose–response relation between sodium reduction and blood pressure change: systematic review and meta-analysis of randomized trials. Journal of Human Hypertension, 35(11), 946-957. [More Information]
- Chow, C., Atkins, E., Billot, L., Chalmers, J., Hillis, G., Hay, P., Neal, B., Nelson, M., Patel, A., Reid, C., Usherwood, T., Rodgers, A., et al (2021). Ultra-low-dose quadruple combination blood pressure–lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol. American Heart Journal, 231, 56-67. [More Information]
- Chen, X., Li, J., Anderson, C., Lindley, R., Hackett, M., Robinson, T., Lavados, P., Wang, X., Arima, H., Chalmers, J., Delcourt, C. (2021). Validation of the simplified modified Rankin scale for stroke trials: Experience from the ENCHANTED alteplase-dose arm. International Journal of Stroke, 16(2), 222-228. [More Information]
- Jun, M., Harris, K., Heerspink, H., Badve, S., Jardine, M., Harrap, S., Hamet, P., Marre, M., Poulter, N., Kotwal, S., Gallagher, M., et al (2021). Variability in estimated glomerular filtration rate and the risk of major clinical outcomes in diabetes: Post hoc analysis from the ADVANCE trial. Diabetes, Obesity and Metabolism, 23(6), 1420-1425. [More Information]
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2020
- Chen, X., Delcourt, C., Sun, L., Zhou, Z., Yoshimura, S., You, S., Malavera, A., Torii-Yoshimura, T., Carcel, C., Arima, H., Hackett, M., Song, L., Lindley, R., Anderson, C., et al (2020). Brain Imaging Signs and Health-Related Quality of Life after Acute Ischemic Stroke: Analysis of ENCHANTED Alteplase Dose Arm. Cerebrovascular Diseases, 49(4), 427-436. [More Information]
- Hua, X., Lung, T., Woodward, M., Salomon, J., Hamet, P., Harrap, S., Mancia, G., Poulter, N., Chalmers, J., Clarke, P. (2020). Self-rated health scores predict mortality among people with type 2 diabetes differently across three different country groupings: findings from the ADVANCE and ADVANCE-ON trials. Diabetic Medicine, 37(8), 1379-1385. [More Information]
- Sandset, E., Wang, X., Carcel, C., Sato, S., Delcourt, C., Arima, H., Stapf, C., Robinson, T., Lavados, P., Chalmers, J., et al (2020). Sex differences in treatment, radiological features and outcome after intracerebral haemorrhage: Pooled analysis of Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage trials 1 and 2. European Stroke Journal, 5(4), 345-350. [More Information]
- Zhou, Z., Yoshimura, S., Delcourt, C., You, S., Malavera, A., Lindley, R., Torii-Yoshimura, T., Wang, X., Chen, X., Parsons, M., Carcel, C., et al (2020). Thrombolysis Outcomes in Acute Ischemic Stroke by Fluid-Attenuated Inversion Recovery Hyperintense Arteries. Stroke, 51(7), 2240-2243. [More Information]
- Wang, X., Moullaali, T., Li, Q., Berge, E., Robinson, T., Lindley, R., Zheng, D., Delcourt, C., Arima, H., Song, L., et al (2020). Utility-Weighted Modified Rankin Scale Scores for the Assessment of Stroke Outcome: Pooled Analysis of 20 000+ Patients. Stroke, 51(8), 2411-2417. [More Information]
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2019
- Robinson, T., Bray, B., Paley, L., Sprigg, N., Wang, X., Arima, H., Bath, P., Broderick, J., Durham, A., Kim, J., et al (2019). Applicability of ENCHANTED trial results to current acute ischemic stroke patients eligible for intravenous thrombolysis in England and Wales: Comparison with the Sentinel Stroke National Audit Programme registry. International Journal of Stroke, 14(7), 678-685. [More Information]
- You, S., Zheng, D., Delcourt, C., Sato, S., Cao, Y., Zhang, S., Yang, J., Wang, X., Lindley, R., Robinson, T., et al (2019). Determinants of Early Versus Delayed Neurological Deterioration in Intracerebral Hemorrhage. Stroke, 50(6), 1409-1414. [More Information]
- Wang, X., Sandset, E., Moullaali, T., Chen, G., Song, L., Carcel, C., Delcourt, C., Woodward, M., Robinson, T., Chalmers, J., Anderson, C., et al (2019). Determinants of the high admission blood pressure in mild-to-moderate acute intracerebral hemorrhage. Journal of Hypertension, 37(7), 1463-1466. [More Information]
- Zhang, Z., Tremblay, J., Raelson, J., Sofer, T., Du, L., Fang, Q., Argos, M., Marois-Blanchet, F., Wang, Y., Yan, L., Chalmers, J., Woodward, M., et al (2019). EPHA4 regulates vascular smooth muscle cell contractility and is a sex-specific hypertension risk gene in individuals with type 2 diabetes. Journal of Hypertension, 37(4), 775-789. [More Information]
- Santo, K., Singleton, A., Rogers, K., Thiagalingam, A., Chalmers, J., Chow, C., Redfern, J. (2019). Medication reminder applications to improve adherence in coronary heart disease: a randomised clinical trial. Heart, 105(4), 323-329. [More Information]
- Carcel, C., Wang, X., Sandset, E., Delcourt, C., Arima, H., Lindley, R., Hackett, M., Lavados, P., Robinson, T., Muñoz Venturelli, P., Anderson, C., et al (2019). Sex differences in treatment and outcome after stroke: Pooled analysis including 19,000 participants. Neurology, 93(24), e2170-e2180. [More Information]
- Robinson, T., Wang, X., Durham, A., Ford, G., Liao, J., Littlewood, S., Roffe, C., White, P., Chalmers, J., Anderson, C. (2019). The National Institute for Health Research Hyperacute Stroke Research Centres and the ENCHANTED trial: The impact of enhanced research infrastructure on trial metrics and patient outcomes. Health Research Policy and Systems, 17(1). [More Information]
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2018
- Mohammedi, K., Chalmers, J., Herrington, W., Li, Q., Mancia, G., Marre, M., Poulter, N., Rodgers, A., Williams, B., Perkovic, V., Woodward, M., et al (2018). Associations between body mass index and the risk of renal events in patients with type 2 diabetes. Nutrition and Diabetes, 8(1), 1-9. [More Information]
- Ohkuma, T., Woodward, M., Chalmers, J. (2018). Cardiac stress and inflammatory markers as predictors of heart failure in patients with type 2 diabetes: The ADVANCE trial. Diabetes care 2017;40:1203-1209. Diabetes Care, 41(3), e39. [More Information]
- Jun, M., Ohkuma, T., Zoungas, S., Colagiuri, S., Mancia, G., Marre, M., Matthews, D., Poulter, N., Williams, B., Rodgers, A., Perkovic, V., et al (2018). Changes in Albuminuria and the Risk of Major Clinical Outcomes in Diabetes: Results From ADVANCE-ON. Diabetes Care, 41(1), 163-170. [More Information]
- Welsh, P., Rankin, N., Li, Q., Mark, P., Wurtz, P., Ala-Korpela, M., Marre, M., Poulter, N., Hamet, P., Chalmers, J., et al (2018). Circulating amino acids and the risk of macrovascular, microvascular and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial. Diabetologia, 61(7), 1581-1591. [More Information]
- Nagel, S., Wang, X., Carcel, C., Robinson, T., Lindley, R., Chalmers, J., Anderson, C. (2018). Clinical Utility of Electronic Alberta Stroke Program Early Computed Tomography Score Software in the ENCHANTED Trial Database. Stroke, 49(6), 1407-1411. [More Information]
- Chen, G., Wang, X., Robinson, T., Pikkemaat, M., Lindley, R., Zhou, S., Ping, L., Liu, W., Liu, L., Chalmers, J., et al (2018). Comparative effects of low-dose versus standard-dose alteplase in ischemic patients with prior stroke and/or diabetes mellitus: The ENCHANTED trial. Journal of the Neurological Sciences, 387, 1-5. [More Information]
- Wang, X., You, S., Sato, S., Yang, J., Carcel, C., Zheng, D., Yoshimura, S., Anderson, C., Sandset, E., Robinson, T., Chalmers, J., et al (2018). Current status of intravenous tissue plasminogen activator dosage for acute ischaemic stroke: an updated systematic review. Stroke and Vascular Neurology, 3(1), 28-33. [More Information]
- van Steen, S., Woodward, M., Chalmers, J., Li, Q., Marre, M., Cooper, M., Hamet, P., Mancia, G., Colagiuri, S., Williams, B., et al (2018). Haemoglobin glycation index and risk for diabetes-related complications in the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial. Diabetologia, 61(4), 780-789. [More Information]
- Mundra, P., Barlow, C., Nestel, P., Barnes, E., Kirby, A., Thompson, P., Sullivan, D., Alshehry, Z., Mellett, N., Huynh, K., Simes, R., et al (2018). Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention. JCI Insight, 3(17), e121326. [More Information]
- Kim, J., Kim, Y., Lee, K., Cha, J., Park, J., Hwang, Y., Kim, E., Rha, J., Koo, J., Kim, J., Lindley, R., Wang, X., Chalmers, J., Anderson, C., et al (2018). Low- versus Standard-Dose Intravenous Alteplase in the Context of Bridging Therapy for Acute Ischemic Stroke: A Korean ENCHANTED Study. Journal of Stroke, 20(1), 131-139. [More Information]
- Anderson, C., Woodward, M., Chalmers, J. (2018). More on Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke. New England Journal of Medicine, 378(15), 1465-1466. [More Information]
- Yoshimura, S., Lindley, R., Carcel, C., Sato, S., Delcourt, C., Wang, X., Chalmers, J., Anderson, C. (2018). NIHSS cut point for predicting outcome in supra- vs infratentorial acute ischemic stroke. Neurology, 91(18), e1695-e1701. [More Information]
- Nowson, C., Lim, K., Land, M., Webster, J., Shaw, J., Chalmers, J., Flood, V., Woodward, M., Grimes, C. (2018). Salt intake and dietary sources of salt on week days and weekend days in Australian adults. Public Health Nutrition, 21(12), 2174-2182. [More Information]
- Santo, K., Hyun, K., de Keizer, L., Thiagalingam, A., Hillis, G., Chalmers, J., Redfern, J., Chow, C. (2018). The effects of a lifestyle-focused text-messaging intervention on adherence to dietary guideline recommendations in patients with coronary heart disease: An analysis of the TEXT ME study. International Journal of Behavioral Nutrition and Physical Activity, 15(1), 1-11. [More Information]
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2017
- Delcourt, C., Zheng, D., Chen, X., Hackett, M., Arima, H., Hata, J., Heeley, E., Salman, R., Woodward, M., Huang, Y., Lindley, R., Davies, L., Chalmers, J., Anderson, C., Sato, S., et al (2017). Associations with health-related quality of life after intracerebral haemorrhage: pooled analysis of INTERACT studies. Journal of Neurology, Neurosurgery and Psychiatry, 88(1), 70-75. [More Information]
- Schilling, C., Knight, J., Mortimer, D., Petrie, D., Clarke, P., Chalmers, J., Kerr, A., Jackson, R. (2017). Australian general practitioners initiate statin therapy primarily on the basis of lipid levels; New Zealand general practitioners use absolute risk. Health Policy, 121(12), 1233-1239. [More Information]
- Ohkuma, T., Jun, M., Woodward, M., Zoungas, S., Cooper, M., Grobbee, D., Hamet, P., Mancia, G., Williams, B., Welsh, P., Chalmers, J., et al (2017). Cardiac stress and inflammatory markers as predictors of heart failure in patients with type 2 diabetes: The ADVANCE trial. Diabetes Care, 40(9), 1203-1209. [More Information]
- Song, L., Wang, X., Robinson, T., Lindley, R., Arima, H., Lavados, P., Chen, X., Chalmers, J., Anderson, C. (2017). Characteristics, management and response to alteplase in China versus non-China participants of the ENCHANTED trial. Stroke and Vascular Neurology, 2(2), 53-58. [More Information]
- Mohammedi, K., Woodward, M., Marre, M., Colagiuri, S., Cooper, M., Harrap, S., Mancia, G., Poulter, N., Williams, B., Zoungas, S., Chalmers, J. (2017). Comparative effects of microvascular and macrovascular disease on the risk of major outcomes in patients with type 2 diabetes. Cardiovascular Diabetology, 16(1), 1-9. [More Information]
- Hirakawa, Y., Arima, H., Rodgers, A., Woodward, M., Chalmers, J. (2017). Cumulative in-trial and post-trial effects of blood pressure and lipid lowering: systematic review and meta-analysis. Journal of Hypertension, 35(5), 905-913. [More Information]
- Santos, J., Webster, J., Land, M., Flood, V., Chalmers, J., Woodward, M., Neal, B., Petersen, K. (2017). Dietary salt intake in the Australian population. Public Health Nutrition, 20(11), 1887-1894. [More Information]
- You, S., Wang, X., Lindley, R., Robinson, T., Anderson, C., Cao, Y., Chalmers, J. (2017). Early Cognitive Impairment after Intracerebral Hemorrhage in the INTERACT1 Study. Cerebrovascular Diseases, 44(5-6), 320-324. [More Information]
- Zoungas, S., Arima, H., Gerstein, H., Holman, R., Woodward, M., Reaven, P., Hayward, R., Craven, T., Coleman, R., Chalmers, J. (2017). Effects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: a meta-analysis of individual participant data from randomised controlled trials. The Lancet Diabetes and Endocrinology, 5(6), 431-437. [More Information]
- Bennett, A., Chow, C., Chou, M., Dehbi, H., Webster, R., Salam, A., Patel, A., Neal, B., Peiris, D., Thakkar, J., Chalmers, J., Woodward, M., Hilmer, S., Usherwood, T., Rodgers, A., et al (2017). Efficacy and Safety of Quarter-Dose Blood Pressure-Lowering Agents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Hypertension, 70(1), 85-93. [More Information]
- Richtering, S., Hyun, K., Neubeck, A., Coorey, G., Chalmers, J., Usherwood, T., Peiris, D., Chow, C., Redfern, J. (2017). eHealth Literacy: Predictors in a Population With Moderate-to-High Cardiovascular Risk. JMIR Human Factors, 4(1), e4. [More Information]
- Tremblay, J., Wang, Y., Raelson, J., Marois-Blanchet, F., Wu, Z., Luo, H., Bradley, E., Chalmers, J., Woodward, M., Harrap, S., et al (2017). Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene. Scientific Reports, 7, 1-10. [More Information]
- Richtering, S., Morris, R., Soh, S., Barker, A., Bampi, F., Neubeck, A., Coorey, G., Mulley, J., Chalmers, J., Usherwood, T., Peiris, D., Chow, C., Redfern, J. (2017). Examination of an eHealth literacy scale and a health literacy scale in a population with moderate to high cardiovascular risk: Rasch analyses. PloS One, 12(4), 1-14. [More Information]
- Xu, Y., Hackett, M., Chalmers, J., Lindley, R., Wang, X., Li, Q., Robinson, T., Arima, H., Lavados, P., Anderson, C. (2017). Frequency, determinants, and effects of early seizures after thrombolysis for acute ischemic stroke: The ENCHANTED trial. Neurology: Clinical Practice, 7(4), 324-332. [More Information]
- Chalmers, J. (2017). Guidelines under fire again!. Journal of Hypertension, 35(8), 1567-1568. [More Information]
- Carr, S., Wang, X., Olavarria, V., Lavados, P., Rodriguez, J., Kim, J., Lee, T., Lindley, R., Pontes-Neto, O., Ricci, S., Anderson, C., et al (2017). Influence of Renal Impairment on Outcome for Thrombolysis-Treated Acute Ischemic Stroke: ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) Post Hoc Analysis. Stroke, 48(9), 2605-2609. [More Information]
- Delcourt, C., Sato, S., Zhang, S., Sandset, E., Zheng, D., Chen, X., Hackett, M., Arima, H., Hata, J., Heeley, E., Davies, L., Lindley, R., Chalmers, J., Anderson, C., et al (2017). Intracerebral hemorrhage location and outcome among INTERACT2 participants. Neurology, 88(15), 1408-1414. [More Information]
- Wang, X., Robinson, T., Lee, T., Li, Q., Arima, H., Bath, P., Billot, L., Broderick, J., Demchuk, A., Donnan, G., Lindley, R., Woodward, M., Anderson, C., Chalmers, J., et al (2017). Low-dose vs standard-dose alteplase for patients with acute ischemic stroke: Secondary analysis of the ENCHANTED randomized clinical trial. JAMA Neurology, 74(11), 1328-1335. [More Information]
- Santo, K., Chow, C., Thiagalingam, A., Rogers, K., Chalmers, J., Redfern, J. (2017). MEDication reminder APPs to improve medication adherence in Coronary Heart Disease (MedApp-CHD) Study: A randomised controlled trial protocol. BMJ Open, 7(10), 1-9. [More Information]
- Zoungas, S., Gerstein, H., Holman, R., Reaven, P., Woodward, M., Arima, H., Coleman, R., Chalmers, J. (2017). Microvascular outcomes in type 2 diabetes – Authors' reply. The Lancet Diabetes and Endocrinology, 5(8), 580-580. [More Information]
- Yang, J., Wang, X., Yu, J., Hang, J., Lavados, P., Robinson, T., Arima, H., Lindley, R., Anderson, C., Chalmers, J. (2017). Positive impact of the participation in the ENCHANTED trial in reducing Door-to-Needle Time. Scientific Reports, 7, 1-6. [More Information]
- Guo, R., Blacker, D., Wang, X., Arima, H., Lavados, P., Lindley, R., Chalmers, J., Anderson, C., Robinson, T. (2017). Practice Patterns for Neurosurgical Utilization and Outcome in Acute Intracerebral Hemorrhage: Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials 1 and 2 Studies. Neurosurgery, 81(6), 980-985. [More Information]
- Moullaali, T., Sato, S., Wang, X., Rabinstein, A., Arima, H., Carcel, C., Chen, G., Robinson, T., Heeley, E., Chan, E., Delcourt, C., Lindley, R., Chalmers, J., Anderson, C., et al (2017). Prognostic significance of delayed intraventricular haemorrhage in the INTERACT studies. Journal of Neurology, Neurosurgery and Psychiatry, 88(1), 19-24. [More Information]
- Ohkuma, T., Woodward, M., Jun, M., Muntner, P., Hata, J., Colagiuri, S., Harrap, S., Mancia, G., Poulter, N., Williams, B., Chalmers, J., et al (2017). Prognostic Value of Variability in Systolic Blood Pressure Related to Vascular Events and Premature Death in Type 2 Diabetes Mellitus: The ADVANCE-ON Study. Hypertension, 70(2), 461-468. [More Information]
- Hamet, P., Haloui, M., Harvey, F., Marois-Blanchet, F., Sylvestre, M., Tahir, M., Simon, P., Kanzki, B., Raelson, J., Long, C., Chalmers, J., Woodward, M., et al (2017). PROX1 gene CC genotype as a major determinant of early onset of type 2 diabetes in slavic study participants from Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation study. Journal of Hypertension, 35(Suppl 1), S24-S32. [More Information]
- Chow, C., Thakkar, J., Bennett, A., Hillis, G., Burke, M., Usherwood, T., Vo, K., Rogers, K., Atkins, E., Webster, R., Salam, A., Patel, A., Neal, B., Peiris, D., Chalmers, J., Woodward, M., Hilmer, S., Rodgers, A., et al (2017). Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review. The Lancet, 389(10073), 1035-1042. [More Information]
- Bolmsjo, B., Molstad, S., Gallagher, M., Chalmers, J., Ostgren, C., Midlov, P. (2017). Risk factors and consequences of decreased kidney function in nursing home residents: A longitudinal study. Geriatrics and Gerontology International, 17(5), 791-797. [More Information]
- Atkins, E., Hirakawa, Y., Salam, A., Woodward, M., Cooper, M., Hamet, P., Harrap, S., Lees, K., Liu, L., Mancia, G., Perkovic, V., Rodgers, A., et al (2017). Side effects and tolerability of combination blood pressure lowering according to blood pressure levels: An analysis of the PROGRESS and ADVANCEtrials. Journal of Hypertension, 35(6), 1318-1325. [More Information]
- Blomster, J., Zoungas, S., Woodward, M., Neal, B., Harrap, S., Poulter, N., Marre, M., Williams, B., Chalmers, J., Hillis, G. (2017). The impact of level of education on vascular events and mortality in patients with type 2 diabetes mellitus: Results from the ADVANCE study. Diabetes Research and Clinical Practice, 127, 212-217. [More Information]
- Brugts, J., Bertrand, M., Remme, W., Ferrari, R., Fox, K., MacMahon, S., Chalmers, J., Simoons, M., Boersma, E. (2017). The Treatment Effect of an ACE-Inhibitor Based Regimen with Perindopril in Relation to Beta-Blocker use in 29,463 Patients with Vascular Disease: a Combined Analysis of Individual Data of ADVANCE, EUROPA and PROGRESS Trials. Cardiovascular Drugs and Therapy, 31(4), 391-400. [More Information]
- Lenander, C., Midlov, P., Viberg, N., Chalmers, J., Rogers, K., Bondesson, A. (2017). Use of Antipsychotic Drugs by Elderly Primary Care Patients and the Effects of Medication Reviews: A Cross-Sectional Study in Sweden. Drugs - Real World Outcomes, 4(3), 159-165. [More Information]
- Hua, X., Erreygers, G., Chalmers, J., Laba, T., Clarke, P. (2017). Using administrative data to look at changes in the level and distribution of out-of-pocket medical expenditure: An example using Medicare data from Australia. Health Policy, 121(4), 426-433. [More Information]
- Munoz Venturelli, P., Zahuranec, D., Wang, X., Lavados, P., Stapf, C., Lindley, R., Delcourt, C., Chalmers, J., Anderson, C., Robinson, T. (2017). Withdrawal of active treatment after intracerebral haemorrhage in the INTERACT2 study. Age and Ageing, 46(2), 329-332. [More Information]
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2016
- Mohammedi, K., Woodward, M., Zoungas, S., Li, Q., Harrap, S., Patel, A., Marre, M., Chalmers, J. (2016). Absence of Peripheral Pulses and Risk of Major Vascular Outcomes in Patients With Type 2 Diabetes. Diabetes Care, 39(12), 2270-2277. [More Information]
- Qiu, M., Sato, S., Zheng, D., Wang, X., Carcel, C., Hirakawa, Y., Sandset, E., Delcourt, C., Arima, H., Wang, J., Chalmers, J., Anderson, C. (2016). Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies. Stroke, 47(6), 1479-1485. [More Information]
- Ettehad, D., Emdin, C., Kiran, A., Anderson, S., Callender, T., Emberson, J., Chalmers, J., Rodgers, A., Rahimi, K. (2016). Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. The Lancet, 387(10022), 957-967. [More Information]
- Hayes, A., Arima, H., Woodward, M., Chalmers, J., Poulter, N., Hamet, P., Clarke, P. (2016). Changes in Quality of Life Associated with Complications of Diabetes: Results from the ADVANCE Study. Value in Health, 19(1), 36-41. [More Information]
- Wong, G., Staplin, N., Emberson, J., Baigent, C., Turner, R., Chalmers, J., Zoungas, S., Pollock, C., Cooper, B., Harris, D., Wang, J., Mitchell, P., Chapman, J., Craig, J., et al (2016). Chronic kidney disease and the risk of cancer: An individual patient data meta-analysis of 32,057 participants from six prospective studies. BMC Cancer, 16(1), 1-11. [More Information]
- Zheng, D., Satoh, S., Cao, Y., Arima, H., Carcel, C., Chalmers, J., Anderson, C. (2016). Circadian variation in clinical features and outcome of intracerebral hemorrhage: The INTERACT studies. Chronobiology International, 33(9), 1182-1187. [More Information]
- Carcel, C., Wang, X., Sato, S., Stapf, C., Sandset, E., Delcourt, C., Arima, H., Robinson, T., Lavados, P., Chalmers, J., Anderson, C. (2016). Degree and Timing of Intensive Blood Pressure Lowering on Hematoma Growth in Intracerebral Hemorrhage: Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial-2 Results. Stroke, 47(6), 1651-1653. [More Information]
- Sato, S., Delcourt, C., Zhang, S., Arima, H., Heeley, E., Zheng, D., Salman, R., Stapf, C., Tzourio, C., Robinson, T., Lindley, R., Chalmers, J., Anderson, C. (2016). Determinants and prognostic significance of hematoma sedimentation levels in acute intracerebral hemorrhage. Cerebrovascular Diseases, 41(1-2), 80-86. [More Information]
- Chalmers, J. (2016). Diabetes and hypertension: Is double therapy useful? Dialogues in Cardiovascular Medicine, 21(2), 124-135.
- Chan, E., Anderson, C., Wang, X., Arima, H., Saxena, A., Moullaali, T., Delcourt, C., Wu, G., Wang, J., Chen, G., Chalmers, J., et al (2016). Early Blood Pressure Lowering Does Not Reduce Growth of Intraventricular Hemorrhage following Acute Intracerebral Hemorrhage: Results of the INTERACT Studies. Cerebrovascular Diseases Extra, 6(3), 71-75. [More Information]
- Song, L., Sandset, E., Arima, H., Heeley, E., Delcourt, C., Chen, G., Wang, X., Lavados, P., Huang, Y., Stapf, C., Chalmers, J., Lindley, R., Anderson, C., et al (2016). Early blood pressure lowering in patients with intracerebral haemorrhage and prior use of antithrombotic agents: Pooled analysis of the INTERACT studies. Journal of Neurology, Neurosurgery and Psychiatry, 87(12), 1330-1335. [More Information]
- Land, M., Wu, J., Selwyn, A., Crino, M., Woodward, M., Chalmers, J., Webster, J., Nowson, C., Jeffery, P., Smith, W., Flood, V., Neal, B. (2016). Effects of a community-based salt reduction program in a regional Australian population. BMC Public Health, 16(1), 1-11. [More Information]
- Xie, X., Atkins, E., Lv, J., Bennett, A., Neal, B., Ninomiya, T., Woodward, M., MacMahon, S., Turnbull, F., Hillis, G., Chalmers, J., Salam, A., Perkovic, V., Rodgers, A., et al (2016). Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. The Lancet, 387(10017), 435-443. [More Information]
- Zheng, D., Sato, S., Arima, H., Heeley, E., Delcourt, C., Cao, Y., Chalmers, J., Anderson, C. (2016). Estimated GFR and the Effect of Intensive Blood Pressure Lowering after Acute Intracerebral Hemorrhage. American Journal of Kidney Diseases, 68(1), 94-102. [More Information]
- van der Leeuw, J., Visseren, F., Woodward, M., van der Graaf, Y., Grobbee, D., Harrap, S., Heller, S., Mancia, G., Marre, M., Poulter, N., Zoungas, S., Chalmers, J. (2016). Estimation of individual beneficial and adverse effects of intensive glucose control for patients with type 2 diabetes. Diabetologia, 59(12), 2603-2612. [More Information]
- Teumer, A., Tin, A., Sorice, R., Gorski, M., Yeo, N., Chu, A., Li, M., Li, Y., Mijatovic, V., Chalmers, J., Woodward, M., et al (2016). Genome-wide association studies identify genetic loci associated with Albuminuria in diabetes. Diabetes, 65(3), 803-817. [More Information]
- Wolff, M., Rogers, K., Erdal, B., Chalmers, J., Sundquist, K., Midlov, P. (2016). Impact of a short home-based yoga programme on blood pressure in patients with hypertension: A randomized controlled trial in primary care. Journal of Human Hypertension, 30(10), 599-605. [More Information]
- Thakkar, J., Heeley, E., Chalmers, J., Chow, C. (2016). Inaccurate risk perceptions contribute to treatment gaps in secondary prevention of cardiovascular disease. Internal Medicine Journal, 46(3), 339-346. [More Information]
- Santo, K., Kirkendall, S., Laba, T., Thakkar, J., Webster, R., Chalmers, J., Chow, C., Redfern, J. (2016). Interventions to improve medication adherence in coronary disease patients: A systematic review and meta-analysis of randomised controlled trials. European Journal of Preventive Cardiology, 23(10), 1065-1076. [More Information]
- Joshy, G., Arora, M., Korda, R., Chalmers, J., Banks, E. (2016). Is poor oral health a risk marker for incident cardiovascular disease hospitalisation and all-cause mortality? Findings from 172 630 participants from the prospective 45 and Up Study. BMJ Open, 6(8), 1-10. [More Information]
- Wong, M., Perkovic, V., Chalmers, J., Woodward, M., Li, Q., Cooper, M., Hamet, P., Harrap, S., Heller, S., MacMahon, S., Neal, B., Rodgers, A., Zoungas, S., et al (2016). Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON. Diabetes Care, 39(5), 694-700. [More Information]
- Zheng, D., Arima, H., Sato, S., Gasparrini, A., Heeley, E., Delcourt, C., Lo, S., Huang, Y., Wang, J., Stapf, C., Chalmers, J., Anderson, C., et al (2016). Low Ambient Temperature and Intracerebral Hemorrhage: The INTERACT2 Study. PloS One, 11(2), 1-14. [More Information]
- Anderson, C., Robinson, T., Lindley, R., Arima, H., Lavados, P., Lee, T., Broderick, J., Chen, X., Chen, G., Sharma, V., Billot, L., Woodward, M., Li, Q., Wang, X., Chalmers, J., et al (2016). Low-dose versus standard-dose intravenous alteplase in acute ischemic stroke. New England Journal of Medicine, 374(24), 2313-2323. [More Information]
- Palatini, P., Rosei, E., Casiglia, E., Chalmers, J., Ferrari, R., Grassi, G., Inoue, T., Jelakovic, B., Jensen, M., et al (2016). Management of the hypertensive patient with elevated heart rate: Statement of the Second Consensus Conference endorsed by the European Society of Hypertension. Journal of Hypertension, 34(5), 813-821. [More Information]
- Mohammedi, K., Woodward, M., Hirakawa, Y., Zoungas, S., Williams, B., Lisheng, L., Rodgers, A., Mancia, G., Neal, B., Harrap, S., Chalmers, J., et al (2016). Microvascular and macrovascular disease and risk for major peripheral arterial disease in patients with type 2 diabetes. Diabetes Care, 39(10), 1796-1803. [More Information]
- Santo, K., Richtering, S., Chalmers, J., Thiagalingam, A., Chow, C., Redfern, J. (2016). Mobile Phone Apps to Improve Medication Adherence: A Systematic Stepwise Process to Identify High-Quality Apps. JMIR mHealth and uHealth, 4(4), 1-10. [More Information]
- Alshehry, Z., Mundra, P., Barlow, C., Mellett, N., Wong, G., McConville, M., Simes, R., Tonkin, A., Sullivan, D., Barnes, E., Neal, B., et al (2016). Plasma lipidomic profiles improve upon traditional risk factors for the prediction of cardiovascular events in Type 2 diabetes. Circulation, 134(21), 1637-1650. [More Information]
- Woodward, M., Hirakawa, Y., Kengne, A., Matthews, D., Zoungas, S., Patel, A., Poulter, N., Grobbee, R., Cooper, M., Jardine, M., Chalmers, J. (2016). Prediction of 10-year vascular risk in patients with diabetes: the AD-ON risk score. Diabetes, Obesity and Metabolism, 18(3), 289-294. [More Information]
- Mohammedi, K., Woodward, M., Hirakawa, Y., Zoungas, S., Colagiuri, S., Hamet, P., Harrap, S., Poulter, N., Matthews, D., Marre, M., Chalmers, J. (2016). Presentations of major peripheral arterial disease and risk of major outcomes in patients with type 2 diabetes: results from the ADVANCE-ON study. Cardiovascular Diabetology, 15(1), 1-9. [More Information]
- Saxena, A., Anderson, C., Wang, X., Sato, S., Arima, H., Chan, E., Munoz Venturelli, P., Delcourt, C., Robinson, T., Stapf, C., Neal, B., Chalmers, J., Heeley, E., et al (2016). Prognostic Significance of Hyperglycemia in Acute Intracerebral Hemorrhage: The INTERACT2 Study. Stroke, 47(3), 682-688. [More Information]
- Carcel, C., Sato, S., Zheng, D., Heeley, E., Arima, H., Yang, J., Wu, G., Chen, G., Zhang, S., Delcourt, C., Lindley, R., Wang, X., Chalmers, J., Anderson, C., et al (2016). Prognostic significance of hyponatremia in acute intracerebral hemorrhage: Pooled analysis of the intensive blood pressure reduction in acute cerebral hemorrhage trial studies. Critical Care Medicine, 44(7), 1388-1394. [More Information]
- Munoz Venturelli, P., Wang, X., Lavados, P., Stapf, C., Robinson, T., Lindley, R., Heeley, E., Delcourt, C., Chalmers, J., Anderson, C. (2016). Prophylactic heparin in acute intracerebral hemorrhage: a propensity score-matched analysis of the INTERACT2 study. International Journal of Stroke, 11(5), 549-556. [More Information]
- Wang, Y., Hamet, P., Thorin, E., Tremblay, J., Raelson, J., Wu, Z., Luo, H., Jin, W., Lavoie, J., Chalmers, J., Woodward, M., et al (2016). Reduced blood pressure after smooth muscle EFNB2 deletion and the potential association of EFNB2 mutation with human hypertension risk. European Journal of Human Genetics, 24(12), 1817-1825. [More Information]
- Hirakawa, Y., Arima, H., Webster, R., Zoungas, S., Li, Q., Harrap, S., Lisheng, L., Hamet, P., Mancia, G., Poulter, N., Neal, B., Rodgers, A., Woodward, M., Chalmers, J., et al (2016). Risks associated with permanent discontinuation of blood pressure-lowering medications in patients with type 2 diabetes. Journal of Hypertension, 34(4), 781-787. [More Information]
- Sato, S., Delcourt, C., Heeley, E., Arima, H., Zhang, S., Salman, R., Stapf, C., Woo, D., Flaherty, M., Vagal, A., Davies, L., Lindley, R., Chalmers, J., Anderson, C., et al (2016). Significance of Cerebral Small-Vessel Disease in Acute Intracerebral Hemorrhage. Stroke, 47(3), 701-707. [More Information]
- Delcourt, C., Zhang, S., Arima, H., Sato, S., Salman, R., Wang, X., Davies, L., Stapf, C., Robinson, T., Lavados, P., Chalmers, J., Lindley, R., Anderson, C., et al (2016). Significance of Hematoma Shape and Density in Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Intracerebral Hemorrhage Trial Study. Stroke, 47(5), 1227-1232. [More Information]
- Chalmers, J., Woodward, M., Borghi, C., Manolis, A., Mancia, G. (2016). Strategies to meet the need for long-term data. Journal of Hypertension, 34(8), 1473-1479. [More Information]
- Blomster, J., Woodward, M., Zoungas, S., Hillis, G., Harrap, S., Neal, B., Poulter, R., Mancia, G., Chalmers, J., Huxley, R. (2016). The harms of smoking and benefits of smoking cessation in women compared with men with type 2 diabetes: an observational analysis of the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron modified release Controlled Evaluation) trial. BMJ Open, 6(1), 1-7. [More Information]
- Radholm, K., Wirehn, A., Chalmers, J., Ostgren, C. (2016). Use of antidiabetic and antidepressant drugs is associated with increased risk of myocardial infarction: A nationwide register study. Diabetic Medicine, 33(2), 218-223. [More Information]
- Schilling, C., Mortimer, D., Dalziel, K., Heeley, E., Chalmers, J., Clarke, P. (2016). Using Classification and Regression Trees (CART) to Identify Prescribing Thresholds for Cardiovascular Disease. PharmacoEconomics, 34(2), 195-205. [More Information]
- Yu, S., Arima, H., Heeley, E., Delcourt, C., Krause, M., Peng, B., Yang, J., Wu, G., Chen, X., Chalmers, J., Anderson, C. (2016). White blood cell count and clinical outcomes after intracerebral hemorrhage: The INTERACT2 trial. Journal of the Neurological Sciences, 361, 112-116. [More Information]
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2015
- Zheng, D., Arima, H., Heeley, E., Karpin, A., Yang, J., Chalmers, J., Anderson, C. (2015). Ambient temperature and volume of perihematomal edema in acute intracerebral haemorrhage: the INTERACT1 study. International Journal of Stroke, 10(1), 25-27. [More Information]
- Chalmers, J. (2015). Blood pressure control after a stroke: A continuing challenge!. Journal of Hypertension, 33(10), 2022-2024. [More Information]
- Chalmers, J. (2015). Can blood pressure-lowering therapy reduce the risk of cognitive decline in the elderly? Journal of Hypertension, 33(10), 2029-2031. [More Information]
- Nowson, C., Lim, K., Grimes, C., O'Halloran, S., Land, M., Webster, J., Shaw, J., Chalmers, J., Smith, W., Flood, V., Woodward, M., Neal, B. (2015). Dietary salt intake and discretionary salt use in two general population samples in Australia: 2011 and 2014. Nutrients, 7(12), 10501-10512. [More Information]
- Sundstrom, J., Arima, H., Jackson, R., Turnbull, F., Rahimi, K., Chalmers, J., Woodward, M., Neal, B. (2015). Effects of Blood Pressure Reduction in Mild Hypertension: A Systematic Review and Meta-analysis. Annals of Internal Medicine, 162(3), 184-191. [More Information]
- Messaoudi, S., He, Y., Gutsol, A., Wight, A., Hebert, R., Vilmundarson, R., Makrigiannis, A., Chalmers, J., Hamet, P., Tremblay, J., et al (2015). Endothelial Gata5 transcription factor regulates blood pressure. Nature Communications, 6, 1-13. [More Information]
- Matsushita, K., Coresh, J., Sang, Y., Chalmers, J., Fox, C., Guallar, E., Jafar, T., Jassal, S., Landman, G., Muntner, P., Woodward, M., et al (2015). Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data. The Lancet Diabetes and Endocrinology, 3(7), 514-525. [More Information]
- Gorski, M., Tin, A., Garnaas, M., McMahon, G., Chu, A., Tayo, B., Pattaro, C., Teumer, A., Chasman, D., Chalmers, J., Woodward, M., Mitchell, P., Wang, J., et al (2015). Genome-wide association study of kidney function decline in individuals of European descent. Kidney International, 87(5), 1017-1029. [More Information]
- Sato, S., Heeley, E., Arima, H., Delcourt, C., Hirakawa, Y., Pamidimukkala, V., Li, Z., Tao, Q., Xu, Y., Hennerici, M., Lindley, R., Chalmers, J., Anderson, C., et al (2015). Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2. Journal of Neurology, Neurosurgery and Psychiatry, 86(12), 1319-1323. [More Information]
- Chalmers, J. (2015). Hypertension Guidelines: Timely New Initiatives from East Asia. Pulse: a transdisciplinary approach to basic and clinical vascular research, 3(1), 1-3. [More Information]
- Santo, K., Chalmers, J., Chow, C., Redfern, J. (2015). m-Health in Coronary Disease Preventive Care. Journal of Cardiology and Therapy, 2(6), 1-8.
- Wang, X., Arima, H., Heeley, E., Delcourt, C., Huang, Y., Wang, J., Stapf, C., Robinson, T., Woodward, M., Chalmers, J., Anderson, C. (2015). Magnitude of Blood Pressure Reduction and Clinical Outcomes in Acute Intracerebral Hemorrhage Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Study. Hypertension, 65(5), 1026-1032. [More Information]
- Wang, X., Arima, H., Yang, J., Zhang, S., Wu, G., Woodward, M., Munoz Venturelli, P., Lavados, P., Stapf, C., Robinson, T., Heeley, E., Delcourt, C., Lindley, R., Chalmers, J., Anderson, C., et al (2015). Mannitol and Outcome in Intracerebral Hemorrhage Propensity Score and Multivariable Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial 2 Results. Stroke, 46(10), 2762-2767. [More Information]
- Knott, R., Clarke, P., Heeley, E., Chalmers, J. (2015). Measuring the Progressivity of the Pharmaceutical Benefits Scheme. Australian Economic Review, 48(2), 122-132. [More Information]
- Sato, S., Arima, H., Heeley, E., Hirakawa, Y., Delcourt, C., Lindley, R., Robinson, T., Huang, Y., Morgenstern, L., Stapf, C., Chalmers, J., Anderson, C., et al (2015). Off-Hour Admission and Outcomes in Patients with Acute Intracerebral Hemorrhage in the INTERACT2 Trial. Cerebrovascular Diseases, 40(3-4), 114-120. [More Information]
- Radholm, K., Arima, H., Lindley, R., Wang, J., Tzourio, C., Robinson, T., Heeley, E., Anderson, C., Chalmers, J. (2015). Older age is a strong predictor for poor outcome in intracerebral haemorrhage: the INTERACT2 study. Age and Ageing, 44(3), 422-427. [More Information]
- Arima, H., Heeley, E., Delcourt, C., Hirakawa, Y., Wang, X., Woodward, M., Robinson, T., Stapf, C., Parsons, M., Lavados, P., Chalmers, J., Anderson, C., et al (2015). Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2. Neurology, 84(5), 464-471. [More Information]
- Heeley, E., Anderson, C., Woodward, M., Arima, H., Robinson, T., Stapf, C., Parsons, M., Lavados, P., Huang, Y., Wang, Y., Chalmers, J., et al (2015). Poor utility of grading scales in acute intracerebral hemorrhage: Results from the INTERACT2 trial. International Journal of Stroke, 10(7), 1101-1107. [More Information]
- van der Leeuw, J., Visseren, F., Woodward, M., Zoungas, S., Kengne, A., van der Graaf, Y., Glasziou, P., Hamet, P., MacMahon, S., Poulter, N., Chalmers, J., et al (2015). Predicting the Effects of Blood Pressure-Lowering Treatment on Major Cardiovascular Events for Individual Patients With Type 2 Diabetes Mellitus: Results From Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation. Hypertension, 65(1), 115-121. [More Information]
- Yang, J., Arima, H., Wu, G., Heeley, E., Delcourt, C., Zhou, J., Chen, G., Wang, X., Zhang, S., Yu, S., Chalmers, J., Anderson, C. (2015). Prognostic significance of perihematomal edema in acute intracerebral hemorrhage: pooled analysis from the intensive blood pressure reduction in acute cerebral hemorrhage trial studies. Stroke, 46(4), 1009-1013. [More Information]
- Huang, Y., Sharma, V., Robinson, T., Lindley, R., Chen, X., Kim, J., Lavados, P., Olavarria, V., Arima, H., Fuentes, S., Woodward, M., Chalmers, J., Anderson, C., et al (2015). Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2-2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment. International Journal of Stroke, 10(5), 778-788. [More Information]
- Chan, E., Anderson, C., Wang, X., Arima, H., Saxena, A., Moullaali, T., Heeley, E., Delcourt, C., Wu, G., Wang, J., Chalmers, J., et al (2015). Significance of intraventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial results. Stroke, 46(3), 653-658. [More Information]
- Anderson, C., Woodward, M., Arima, H., Chen, X., Lindley, R., Wang, X., Chalmers, J. (2015). Statistical analysis plan for evaluating low- vs. standard-dose alteplase in the ENhanced Control of Hypertension and Thrombolysis strokE stuDy (ENCHANTED). International Journal of Stroke, 10(8), 1313-1315. [More Information]
- Poppe, K., Whalley, G., Doughty, R., Woodward, M., Patel, A., Chow, C., Hirakawa, Y., Chalmers, J., Hillis, G., Triggs, C. (2015). The development and feasibility of a composite score of echocardiographic indices that may stratify outcome in patients with diabetes mellitus. International Journal of Cardiology, 182, 244-249. [More Information]
- Knott, R., Petrie, D., Heeley, E., Chalmers, J., Clarke, P. (2015). The effects of reduced copayments on discontinuation and adherence failure to statin medication in Australia. Health Policy, 119, 620-627. [More Information]
- Thomas, M., Woodward, M., Neal, B., Li, Q., Pickering, R., Marre, M., Williams, B., Perkovic, V., Cooper, M., Zoungas, S., Chalmers, J., Hillis, G. (2015). The Relationship Between Levels of Advanced Glycation End-Products and Their Soluble Receptor and Adverse Outcomes in Adults With Type 2 Diabetes. Diabetes Care, 38(10), 1891-1897. [More Information]
- Wolff, M., Memon, A., Chalmers, J., Sundquist, K., Midlov, P. (2015). Yoga's effect on inflammatory biomarkers and metabolic risk factors in a high risk population - a controlled trial in primary care. BMC Cardiovascular Disorders, 15(1), 1-7. [More Information]
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2014
- Fischer, U., Cooney, M., Bull, L., Silver, L., Chalmers, J., Anderson, C., Mehta, Z., Rothwell, P. (2014). Acute post-stroke blood pressure relative to premorbid levels in intracerebral haemorrhage versus major ischaemic stroke: a population-based study. The Lancet Neurology, 13(4), 374-384. [More Information]
- Zheng, D., Arima, H., Heeley, E., Karpin, A., Heller, G., Yang, J., Chalmers, J., Anderson, C. (2014). Ambient Temperature and Severity of Intracerebral Haemorrhage: The INTERACT1 Study. Neuroepidemiology, 42(3), 169-173. [More Information]
- Chalmers, J. (2014). Are the effects of telmisartan more marked in hypertensive patients? Journal of Hypertension, 32(6), 1201-1202. [More Information]
- Gottesman, R., Chalmers, J. (2014). Blood pressure and cerebral ischemia: a continuing dilemma. Neurology, 82(12), 1018-1019. [More Information]
- Manning, L., Hirakawa, Y., Arima, H., Wang, X., Chalmers, J., Wang, J., Lindley, R., Heeley, E., Delcourt, C., Neal, B., Woodward, M., Anderson, C., et al (2014). Blood pressure variability and outcome after acute intracerebral haemorrhage: a post-hoc analysis of INTERACT2, a randomised controlled trial. The Lancet Neurology, 13(4), 364-373. [More Information]
- Lowe, G., Woodward, M., Hillis, G., Rumley, A., Li, Q., Harrap, S., Marre, M., Hamet, P., Patel, A., Poulter, N., Chalmers, J. (2014). Circulating Inflammatory Markers and the Risk of Vascular Complications and Mortality in People With Type 2 Diabetes and Cardiovascular Disease or Risk Factors: The ADVANCE Study. Diabetes, 63(3), 1115-1123. [More Information]
- Weber, M., Schiffrin, E., White, W., Mann, S., Lindholm, L., Kenerson, J., Flack, J., Carter, B., Materson, B., Ram, C., Chalmers, J., et al (2014). Clinical Practice Guidelines for the Management of Hypertension in the Community. A Statement by the American Society of Hypertension and the International Society of Hypertension. Journal of Hypertension, 32(1), 3-15. [More Information]
- Weber, M., Schiffrin, E., White, W., Mann, S., Lindholm, L., Kenerson, J., Flack, J., Carter, B., Materson, B., Ram, C., Chalmers, J., et al (2014). Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. Journal of Clinical Hypertension, 16(1), 14-26. [More Information]
- Arima, H., Anderson, C., Omae, T., Woodward, M., MacMahon, S., Mancia, G., Bousser, M., Tzourio, C., Harrap, S., Liu, L., Neal, B., Chalmers, J. (2014). Degree of blood pressure reduction and recurrent stroke: the PROGRESS trial. Journal of Neurology, Neurosurgery and Psychiatry, 85, 1284-1285. [More Information]
- Welsh, P., Woodward, M., Hillis, G., Li, Q., Marre, M., Williams, B., Poulter, N., Ryan, L., Harrap, S., Patel, A., Chalmers, J., et al (2014). Do Cardiac Biomarkers NT-proBNP and hsTnT Predict Microvascular Events in Patients With Type 2 Diabetes? Results From the ADVANCE Trial. Diabetes Care, 37(8), 2202-2210. [More Information]
- Chalmers, J., Arima, H., Woodward, M., Mancia, G., Poulter, N., Hirakawa, Y., Zoungas, S., Patel, A., Williams, B., Harrap, S. (2014). Effects of Combination of Perindopril, Indapamide, and Calcium Channel Blockers in Patients With Type 2 Diabetes Mellitus: Results From the Action in Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) Trial. Hypertension, 63(2), 259-264. [More Information]
- Zoungas, S., Chalmers, J., Neal, B., Billot, L., Li, Q., Hirakawa, Y., Arima, H., Monaghan, H., Joshi, R., Colagiuri, S., Perkovic, V., Rodgers, A., MacMahon, S., Patel, A., Woodward, M., et al (2014). Follow-up of blood-pressure lowering and glucose control in type 2 diabetes. New England Journal of Medicine, 371(15), 1392-1406. [More Information]
- Chalmers, J. (2014). How far to lower blood pressure in the long term, after a stroke? Journal of Hypertension, 32(4), 746-748. [More Information]
- Zoungas, S., Woodward, M., Li, Q., Cooper, M., Hamet, P., Harrap, S., Heller, S., Marre, M., Patel, A., Poulter, N., Chalmers, J., et al (2014). Impact of age, age at diagnosis and duration of diabetes on the risk of macrovascular and microvascular complications and death in type 2 diabetes. Diabetologia, 57(12), 2465-2474. [More Information]
- Hirakawa, Y., Arima, H., Zoungas, S., Ninomiya, T., Cooper, M., Hamet, P., Mancia, G., Poulter, N., Harrap, S., Woodward, M., Chalmers, J. (2014). Impact of Visit-to-Visit Glycemic Variability on the Risks of Macrovascular and Microvascular Events and All-Cause Mortality in Type 2 Diabetes: The ADVANCE Trial. Diabetes Care, 37(8), 2359-2365. [More Information]
- Van Dieren, S., Kengne, A., Chalmers, J., Beulens, J., Davis, T., Fulcher, G., Heller, S., Patel, A., Colagiuri, S., Hamet, P., Neal, B., Woodward, M., Zoungas, S., et al (2014). Intensification of medication and glycaemic control among patients with type 2 diabetes - the ADVANCE trial. Diabetes, Obesity and Metabolism, 16(5), 426-432. [More Information]
- Land, M., Jeffery, P., Webster, J., Crino, M., Chalmers, J., Woodward, M., Nowson,, C., Smith, W., Flood, V., Neal, B. (2014). Protocol for the implementation and evaluation of a community-based intervention seeking to reduce dietary salt intake in Lithgow, Australia. BMC Public Health, 14(1), 1-7. [More Information]
- Hillis, G., Welsh, P., Chalmers, J., Woodward, M., Sattar, N. (2014). Response to comment on hillis et Al. The relative and combined ability of high-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic Peptide to predict cardiovascular events and death in patients with type 2 diabetes. Diabetes care 2014;37:295-303. Diabetes Care, 37(6), e154-e154. [More Information]
- Ding, D., Rogers, K., Macniven, R., Kamalesh, V., Kritharides, L., Chalmers, J., Bauman, A. (2014). Revisiting Lifestyle Risk Index Assessment in a Large Australian Sample: Are Sedentary Behavior and Sleep Correlated with Health Outcomes. Preventive Medicine, 60, 102-106. [More Information]
- Land, M., Webster, J., Christoforou, A., Praveen, D., Jeffery, P., Chalmers, J., Smith, W., Woodward, M., Barzi, F., Nowson,, C., Neal, B., et al (2014). Salt intake assessed by 24 h urinary sodium excretion in a random and opportunistic sample in Australia. BMJ Open, 4(2), 1-7. [More Information]
- Chen, G., Arima, H., Wu, G., Heeley, E., Delcourt, C., Zhang, P., Rabinstein, A., Robinson, T., Stapf, C., Huang, Y., Song, L., Yang, J., Wang, X., Li, Q., Chen, X., Chalmers, J., Anderson, C. (2014). Subarachnoid Extension of Intracerebral Hemorrhage and 90-Day Outcomes in INTERACT2. Stroke, 45(1), 258-260. [More Information]
- Land, M., Webster, J., Christoforou, A., Johnson, C., Trevena, H., Hodgins, F., Chalmers, J., Woodward, M., Barzi, F., Smith, W., Flood, V., Neal, B., et al (2014). The association of knowledge, attitudes and behaviours related to salt with 24-hour urinary sodium excretion. International Journal of Behavioral Nutrition and Physical Activity, 11(1), 1-8. [More Information]
- Brughts, J., Arima, H., Remme, W., Bertrand, M., Ferrari, R., Fox, K., DiNicolantonio, J., MacMahon, S., Chalmers, J., Zijlstra, F., et al (2014). The incidence and clinical predictors of ACE-inhibitor induced dry cough by perindopril in 27,492 patients with vascular disease. International Journal of Cardiology, 176(3), 718-723. [More Information]
- Blomster, J., Zoungas, S., Chalmers, J., Li, Q., Chow, C., Woodward, M., Mancia, G., Poulter, N., Williams, B., Harrap, S., Neal, B., et al (2014). The relationship between alcohol consumption and vascular complications and mortality in individuals with type 2 diabetes. Diabetes Care, 37(5), 1353-1359. [More Information]
- Hillis, G., Welsh, P., Chalmers, J., Perkovic, V., Chow, C., Li, Q., Jun, M., Neal, B., Zoungas, S., Poulter, N., Woodward, M., et al (2014). The relative and combined ability of high sensitivity cardiac troponin T and N-terminal pro-B-type Natriuretic Peptide to predict cardiovascular events and death in patients with type 2 diabetes. Diabetes Care, 37(1), 295-303. [More Information]
- Sato, S., Arima, H., Hirakawa, Y., Heeley, E., Delcourt, C., Beer, R., Li, Y., Zhang, J., Juettler, E., Wang, J., Lindley, R., Chalmers, J., Anderson, C., et al (2014). The speed of ultraearly hematoma growth in acute intracerebral hemorrhage. Neurology, 83(24), 2232-2238. [More Information]
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2013
- Rist, P., Chalmers, J., Arima, H., Anderson, C., MacMahon, S., Woodward, M., Kurth, T., Tzourio, C. (2013). Baseline Cognitive Function, Recurrent Stroke, and Risk of Dementia in Patients With Stroke. Stroke, 44(7), 1790-1795. [More Information]
- Ninomiya, T., Perkovic, V., Turnbull, F., Neal, B., Barzi, F., Cass, A., Baigent, C., Chalmers, J., Li, N., Woodward, M., MacMahon, S. (2013). Blood pressure lowering and major cardiovascular events in people with and without chronic kidney disease: meta-analysis of randomised controlled trials. BMJ, 347(7929), 1-15. [More Information]
- Perkovic, V., Woodward, M., Zoungas, S., Chalmers, J. (2013). Caution advised in interpreting nonsignificant results from ADVANCE post hoc analysis. Kidney International, 84(3), 622-622. [More Information]
- Wong, M., Perkovic, V., Woodward, M., Chalmers, J., Li, Q., Hillis, G., Azari, E., Jun, M., Poulter, N., Hamet, P., Neal, B., Pollock, C., et al (2013). Circulating bone morphogenetic protein-7 and transforming growth factor-(beta)1 are better predictors of renal end points in patients with type 2 diabetes mellitus. Kidney International, 83(2), 278-284. [More Information]
- Chalmers, J. (2013). Current issues with dual inhibition of the renin-angiotensin system. Journal of Hypertension, 31(2), 261-262. [More Information]
- Hata, J., Arima, H., Zoungas, S., Fulcher, G., Pollock, C., Adams, M., Watson, J., Joshi, R., Kengne, A., Ninomiya, T., Anderson, C., Woodward, M., Patel, A., MacMahon, S., Chalmers, J., Neal, B., et al (2013). Effects of the endpoint adjudication process on the results of a randomised controlled trial: the ADVANCE trial. PloS One, 8(2), 1-7. [More Information]
- Hata, J., Arima, H., Rothwell, P., Woodward, M., Zoungas, S., Anderson, C., Patel, A., Neal, B., Glasziou, P., Hamet, P., MacMahon, S., Chalmers, J., et al (2013). Effects of visit-to-visit variability in systolic blood pressure on macrovascular and microvascular complications in patients with type 2 diabetes mellitus: The ADVANCE trial. Circulation, 128(12), 1325-1334. [More Information]
- Banks, E., Joshy, G., Abhayaratna, W., Kritharides, L., MacDonald, P., Korda, R., Chalmers, J. (2013). Erectile Dysfunction Severity as a Risk Marker for Cardiovascular Disease Hospitalisation and All-Cause Mortality: A Prospective Cohort Study. PLoS Medicine, 10(1), 1-13. [More Information]
- Chalmers, J., Arima, H., Harrap, S., Touyz, R., Park, J. (2013). Global survey of current practice in management of hypertension as reported by societies affiliated with the international society of hypertension. Journal of Hypertension, 31(5), 1043-1048. [More Information]
- Perkovic, V., Heerspink, H., Chalmers, J., Woodward, M., Jun, M., Li, Q., MacMahon, S., Cooper, M., Hamet, P., Marre, M., Cass, A., Patel, A., Zoungas, S., et al (2013). Intensive glucose control improves kidney outcomes in patients with type 2 diabetes. Kidney International, 83(3), 517-523. [More Information]
- Batty, G., Li, Q., Huxley, R., Zoungas, S., Taylor, B., Neal, B., de Galan, B., Woodward, M., Harrap, S., Colagiuri, S., Patel, A., Chalmers, J. (2013). Oral disease in relation to future risk of dementia and cognitive decline: Prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial. European Psychiatry, 28(1), 49-52. [More Information]
- Chalmers, J., Angus, J., Graham, R., Carmody, J., Dampney, R., Jennings, G., Korner, N. (2013). Paul Ivan Korner 1925-2012. Historical Records of Australian Science, 24(2), 251-282. [More Information]
- Anderson, C., Heeley, E., Huang, Y., Wang, J., Stapf, C., Delcourt, C., Lindley, R., Robinson, T., Lavados, P., Neal, B., Hata, J., Arima, H., Heritier, S., Li, Q., Woodward, M., Simes, R., Chalmers, J., et al (2013). Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage. New England Journal of Medicine, 368(25), 2355-2365. [More Information]
- Anderson, C., Heeley, E., Heritier, S., Arima, H., Woodward, M., Lindley, R., Neal, B., Huang, Y., Wang, J., Parsons, M., Delcourt, C., Chalmers, J., et al (2013). Statistical analysis plan for the second INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT2): a large-scale investigation to solve longstanding controversy over the most appropriate management of elevated blood pressure in the hyperacute phase of intracerebral hemorrhage. International Journal of Stroke, 8(5), 327-328. [More Information]
- Morton, J., Ng, M., Chalmers, J., Woodward, M., Mancia, G., Poulter, N., Marre, M., Cooper, M., Zoungas, S. (2013). The Association of High-Density Lipoprotein Cholesterol with Cancer Incidence in Type II Diabetes: A Case of Reverse Causality? Cancer Epidemiology Biomarkers and Prevention, 22(9), 1628-1633. [More Information]
- Justin Zaman, M., Patel, A., Chalmers, J., Woodward, M., Clarke, P., Li, Q., Zoungas, S. (2013). The effects of patient characteristics and geographical region on hospitalization in patients with Type 2 diabetes. Diabetic Medicine, 30(8), 918-925. [More Information]
- Blomster, J., Chow, C., Zoungas, S., Woodward, M., Patel, A., Poulter, N., Marre, M., Harrap, S., Chalmers, J., Hillis, G. (2013). The influence of physical activity on vascular complications and mortality in patients with type 2 diabetes mellitus. Diabetes, Obesity and Metabolism, 15(11), 1008-1012. [More Information]
- Stefansdottir, G., Zoungas, S., Chalmers, J., Knol, M., Leufkens, H., Woodward, M., Patel, A., Grobbee, D., De Bruin, M. (2013). The Post Hoc Use of Randomised Controlled Trials to Explore Drug Associated Cancer Outcomes: Methodological Challenges. Current Drug Safety, 8(5), 371-378. [More Information]
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2012
- Zoungas, S., Chalmers, J., Li, Q., Woodward, M. (2012). ADVANCE and glycaemia thresholds: a need to clarify the statistical approach. Reply to Currie CJ [letter]. Diabetologia, 55(8), 2300-2300. [More Information]
- Zoungas, S., Chalmers, J., Ninomiya, T., Li, Q., Cooper, M., Colagiuri, S., Fulcher, G., de Galan, B., Harrap, S., Hamet, P., Patel, A., Neal, B., Woodward, M., et al (2012). Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Diabetologia, 55(3), 636-643. [More Information]
- Fox, C., Matsushita, K., Woodward, M., Bilo, H., Chalmers, J., Heerspink, H., Lee, B., Perkins, R., Rossing, P., Sairenchi, T., et al (2012). Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. The Lancet, 380(9854), 1662-1673. [More Information]
- Razavian, M., Heeley, E., Perkovic, V., Zoungas, S., Weekes, A., Patel, A., Anderson, C., Chalmers, J., Cass, A. (2012). Cardiovascular risk management in chronic kidney disease in general practice (the AusHEART study). Nephrology Dialysis Transplantation, 27(4), 1396-1402. [More Information]
- Chapman, N., Arima, H., Chalmers, J., Anderson, C. (2012). Cerebrovascular Disease in Hypertension. In Henry R Black and William J Elliott (Eds.), Hypertension: A Companion to Braunwald's Heart Disease, Second Edition, (pp. 392-405). Philadelphia: Elsevier. [More Information]
- Hata, J., Arima, H., Anderson, C., Chalmers, J. (2012). Cognitive Function and Dementia in Hypertension: Epidemiologic and Therapeutic Aspects. In Adel E. Berbari and Giuseppe Mancia (Eds.), Special Issues in Hypertension, (pp. 399-412). Milan, Italy: Springer. [More Information]
- Chalmers, J., Arima, H., Hata, J. (2012). Cost-effective reduction in stroke: lessons from the Japanese hypertension detection and control program. Journal of Hypertension, 30(9), 1706-1707. [More Information]
- Heeley, E., Anderson, C., Patel, A., Cass, A., Peiris, D., Weekes, A., Chalmers, J. (2012). Disparities between prescribing of secondary prevention therapies for stroke and coronary artery disease in general practice. International Journal of Stroke, 7(8), 649-654. [More Information]
- Arima, H., Huang, Y., Wang, J., Heeley, E., Delcourt, C., Parsons, M., Li, Q., Neal, B., Chalmers, J., Anderson, C. (2012). Earlier Blood Pressure-Lowering and Greater Attenuation of Hematoma Growth in Acute Intracerebral Hemorrhage: INTERACT Pilot Phase. Stroke, 43(8), 2236-2238. [More Information]
- Van Dieren, S., Kengne, A., Chalmers, J., Beulens, J., Cooper, M., Grobbee, D., Harrap, S., Mancia, G., Neal, B., Patel, A., Woodward, M., Zoungas, S., et al (2012). Effects of blood pressure lowering on cardiovascular outcomes in different cardiovascular risk groups among participants with type 2 diabetes. Diabetes Research and Clinical Practice, 98(1), 83-90. [More Information]
- Arima, H., Anderson, C., Omae, T., Woodward, M., MacMahon, S., Mancia, G., Bousser, M., Tzourio, C., Rodgers, A., Neal, B., Chalmers, J. (2012). Effects of Blood Pressure Lowering on Intracranial and Extracranial Bleeding in Patients on Antithrombotic Therapy: The PROGRESS Trial. Stroke, 43(6), 1675-1677. [More Information]
- Lv, J., Neal, B., Ehteshami, P., Ninomiya, T., Woodward, M., Rodgers, A., Wang, H., MacMahon, S., Turnbull, F., Hillis, G., Chalmers, J., Perkovic, V. (2012). Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis. PLoS Medicine, 9(8), 1-14. [More Information]
- Salvi, E., Kutalik, Z., Glorioso, N., Benaglio, P., Frau, F., Kuznetsova, T., Arima, H., Hoggart, C., Tichet, J., Nikitin, Y., Chalmers, J., et al (2012). Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase. Hypertension, 59(2), 248-255. [More Information]
- Zoungas, S., Chalmers, J. (2012). Glycemic control and outcomes in people with diabetes and CKD. Nature Reviews Nephrology, 8(3), 133-134. [More Information]
- Delcourt, C., Huang, Y., Arima, H., Chalmers, J., Davis, S., Heeley, E., Wang, J., Parsons, M., Liu, G., Anderson, C. (2012). Hematoma growth and outcomes in intracerebral hemorrhage: The INTERACT1 study. Neurology, 79(4), 314-319. [More Information]
- Knott, R., Cass, A., Heeley, E., Chalmers, J., Peiris, D., Clarke, P. (2012). How fair is Medicare? The income-related distribution of Medicare benefits with special focus on chronic care items. Medical Journal of Australia, 197(11/12), 1-5. [More Information]
- Morton, J., Zoungas, S., Li, Q., Patel, A., Chalmers, J., Woodward, M., Celermajer, D., Beulens, J., Stolk, R., Glasziou, P., Ng, M. (2012). Low HDL Cholesterol and the Risk of Diabetic Nephropathy and Retinopathy: Results of the ADVANCE study. Diabetes Care, 35(11), 2201-2206. [More Information]
- Chalmers, J. (2012). Making Good Use of Diastolic and Systolic Blood Pressures in the Management of Hypertension. Hypertension, 60(5), 1110-1111. [More Information]
- Kengne, A., Sobngwi, E., Chalmers, J. (2012). Multiple risk factor interventions and inflammatory biomarkers in high risk individuals with type 2 diabetes. Diabetes Research and Clinical Practice, 95(3), 386-388. [More Information]
- Jardine, M., Hata, J., Woodward, M., Perkovic, V., Ninomiya, T., Arima, H., Zoungas, S., Cass, A., Patel, A., Marre, M., Chalmers, J., et al (2012). Prediction of Kidney-Related Outcomes in Patients With Type 2 Diabetes. American Journal of Kidney Diseases, 60(5), 770-778. [More Information]
- Hillis, G., Woodward, M., Rodgers, A., Chow, C., Li, Q., Zoungas, S., Patel, A., Webster, R., Batty, G., Ninomiya, T., Chalmers, J., et al (2012). Resting heart rate and the risk of death and cardiovascular complications in patients with type 2 diabetes mellitus. Diabetologia, 55(5), 1283-1290. [More Information]
- Hillis, G., Hata, J., Woodward, M., Perkovic, V., Arima, H., Chow, C., Zoungas, S., Patel, A., Poulter, N., Mancia, G., Chalmers, J., et al (2012). Resting Heart Rate and the Risk of Microvascular Complications in Patients With Type 2 Diabetes Mellitus. Journal of the American Heart Association, 1(5), 1-11. [More Information]
- Wong, G., Zoungas, S., Lo, S., Chalmers, J., Cass, A., Neal, B., Woodward, M., Perkovic, V., Glasziou, P., Williams, B., Howard, K., Chapman, J., Craig, J. (2012). The risk of cancer in people with diabetes and chronic kidney disease. Nephrology Dialysis Transplantation, 27(8), 3337-3344. [More Information]
- Van Dieren, S., Czernichow, S., Chalmers, J., Kengne, A., de Galan, B., Poulter, N., Woodward, M., Beulens, J., Grobbee, D., van der Schouw, Y., Zoungas, S. (2012). Weight changes and their predictors amongst 11 140 patients with type 2 diabetes in the ADVANCE trial. Diabetes, Obesity and Metabolism, 14(5), 464-469. [More Information]
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2011
- Brugts, J., Isaacs, A., de Maat, M., Boersma, E., van Duijn, C., Akkerhuis, K., Uitterlinden, A., Witteman, J., Cambien, F., Ceconi, C., Ninomiya, T., Chalmers, J., MacMahon, S., et al (2011). A Pharmacogenetic Analysis of Determinants of Hypertension and Blood Pressure Response to Angiotensin-Converting Enzyme Inhibitor Therapy in Patients With Vascular Disease and Healthy Individuals. Journal of Hypertension, 29(3), 509-519. [More Information]
- Salomon, J., Patel, A., Neal, B., Glasziou, P., Grobbee, D., Chalmers, J., Clarke, P. (2011). Comparability of Patient-reported Health Status: Multicountry Analysis of EQ-5D Responses in Patients With Type 2 Diabetes. Medical Care, 49(10), 962-969. [More Information]
- Czernichow, S., Kengne, A., Huxley, R., Batty, G., de Galan, B., Grobbee, D., Pillai, A., Zoungas, S., Marre, M., Woodward, M., Neal, B., Chalmers, J. (2011). Comparison of waist-to-hip ratio and other obesity indices as predictors of cardiovascular disease risk in people with type-2 diabetes: a prospective cohort study from ADVANCE. European Journal of Cardiovascular Prevention and Rehabilitation, 18(2), 312-319. [More Information]
- Kengne, A., Patel, A., Marre, M., Travert, F., Lievre, M., Zoungas, S., Chalmers, J., Colagiuri, S., Grobbee, D., Hamet, P., Neal, B., Woodward, M., et al (2011). Contemporary model for cardiovascular risk prediction in people with type 2 diabetes. European Journal of Cardiovascular Prevention and Rehabilitation, 18(3), 393-398. [More Information]
- Woodward, M., Patel, A., Zoungas, S., Liu, L., Pan, C., Poulter, N., Januszewicz, A., Tandon, N., Joshi, P., Heller, S., Neal, B., Chalmers, J. (2011). Does Glycemic Control Offer Similar Benefits Among Patients With Diabetes in Different Regions of the World?: Results from the ADVANCE trial. Diabetes Care, 34(12), 2491-2495. [More Information]
- Arima, H., Anderson, C., Omae, T., Woodward, M., Hata, J., Murakami, Y., MacMahon, S., Neal, B., Chalmers, J., PROGRESS Collaborative Group, -. (2011). Effects of Blood Pressure Lowering on Major Vascular Events Among Patients With Isolated Diastolic Hypertension: The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) Trial. Stroke, 42(8), 2339-2341. [More Information]
- Turnbull, F., Arima, H., Heeley, E., Cass, A., Chalmers, J., Morgan, C., Patel, A., Peiris, D., Weekes, A., Anderson, C. (2011). Gender disparities in the assessment and management of cardiovascular risk in primary care: the AusHEART study. European Journal of Cardiovascular Prevention and Rehabilitation, 18(3), 498-503. [More Information]
- Stefansdottir, G., Zoungas, S., Chalmers, J., Kengne, A., Knol, M., Leufkens, H., Patel, A., Woodward, M., Grobbee, D., De Bruin, M. (2011). Intensive glucose control and risk of cancer in patients with type 2 diabetes. Diabetologia, 54(7), 1608-1614. [More Information]
- Chalmers, J. (2011). Is a Blood Pressure Target of <130/80 mm Hg Still Appropriate for High-Risk Patients? Circulation, 124(16), 1700-1702. [More Information]
- Lee, P., Kengne, A., Greenfield, J., Day, R., Chalmers, J., Ho, K. (2011). Metabolic sequelae of β-blocker therapy: weighing in on the obesity epidemic? International Journal of Obesity, 35(11), 1395-1403. [More Information]
- Arima, H., Barzi, F., Chalmers, J. (2011). Mortality patterns in hypertension. Journal of Hypertension, 29(SUPPL. 1), S3-S7. [More Information]
- Chalmers, J., Kengne, A. (2011). Predictive factors in assessing cardiovascular risk: learning from ADVANCE. Medicographia, 33(1), 47-51.
- Arima, H., Chalmers, J. (2011). PROGRESS: Prevention of recurrent stroke. Journal of Clinical Hypertension, 13(9), 693-702. [More Information]
- Hackam, D., Woodward, M., Newby, L., Bhatt, D., Shao, M., Smith, E., Donner, A., Muhammad, M., Douketis, J., Arima, H., Chalmers, J., MacMahon, S., et al (2011). Statins and Intracerebral Hemorrhage: Collaborative Systematic Review and Meta-analysis. Circulation, 124(20), 2233-2242. [More Information]
- Arima, H., Chalmers, J. (2011). Stroke: Blood pressure lowering in acute stroke-scant joy from SCAST. Nature Reviews Cardiology, 8(7), 366-368. [More Information]
- Czernichow, S., Zanchetti, A., Turnbull, F., Barzi, F., Ninomiya, T., Kengne, A., Heerspink, H., Perkovic, V., Huxley, R., Arima, H., Patel, A., Chalmers, J., Woodward, M., MacMahon, S., Neal, B. (2011). The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials. Journal of Hypertension, 29(1), 4-16. [More Information]
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2010
- Jardine, M., Ninomiya, T., Perkovic, V., Cass, A., Turnbull, F., Gallagher, M., Zoungas, S., Heerspink, H., Chalmers, J., Zanchetti, A. (2010). Aspirin is beneficial in hypertensive patients with chronic kidney disease a post-hoc subgroup analysis of a randomized controlled trial. Journal of the American College of Cardiology, 56(12), 956-965. [More Information]
- Lee, C., Stolk, R., Adler, A., Patel, A., Chalmers, J., Neal, B., Poulter, N., Harrap, S., Woodward, M., Marre, M., et al (2010). Association between alcohol consumption and diabetic retinopathy and visual acuity-the AdRem Study. Diabetic Medicine, 27(10), 1130-1137. [More Information]
- Heeley, E., Peiris, D., Patel, A., Cass, A., Weekes, A., Morgan, C., Anderson, C., Chalmers, J. (2010). Cardiovascular risk perception and evidence-practice gaps in Australian general practice (the AusHEART study). Medical Journal of Australia, 192(5), 254-259. [More Information]
- Glasziou, P., Clarke, P., Alexander, J., Rajmokan, M., Beller, E., Woodward, M., Chalmers, J., Poulter, N., Patel, A. (2010). Cost-effectiveness of lowering blood pressure with a fixed combination of perindopril and indapamide in type 2 diabetes mellitus: an ADVANCE trial-based analysis. Medical Journal of Australia, 193(6), 320-324. [More Information]
- Head, G., Mihailidou, A., Duggan, K., Beilin, L., Berry, N., Brown, M., Bune, A., Cowley, D., Chalmers, J., Howe, P., et al (2010). Definition of ambulatory blood pressure targets for diagnosis and treatment of hypertension in relation to clinic blood pressure: prospective cohort study. BMJ: British Medical Journal, 340(7751), 1-8. [More Information]
- Lambers Heerspink, H., Ninomiya, T., Perkovic, V., Woodward, M., Zoungas, S., Cass, A., Cooper, M., Grobbee, D., Mancia, G., Mogensen, C., Neal, B., Chalmers, J. (2010). Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease. European Heart Journal, 31(23), 2888-2896. [More Information]
- Anderson, C., Huang, Y., Arima, H., Heeley, E., Skulina, C., Parsons, M., Peng, B., Li, Q., Su, S., Tao, Q., Chalmers, J., et al (2010). Effects of Early Intensive Blood Pressure-Lowering Treatment on the Growth of Hematoma and Perihematomal Edema in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial(INTERACT). Stroke, 41(2), 307-312. [More Information]
- Neal, B., Jun, M., Foote, C., Lv, J., Patel, A., Nicholls, S., Grobbee, D., Cass, A., Chalmers, J., Perkovic, V. (2010). Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis. The Lancet, 375(9729), 1875-1884. [More Information]
- Arima, H., Tzourio, C., Anderson, C., Woodward, M., Bousser, M., MacMahon, S., Neal, B., Chalmers, J. (2010). Effects of Perindopril-Based Lowering of Blood Pressure on Intracerebral Hemorrhage Related to Amyloid Angiopathy. The PROGRESS Trial. Stroke, 41(2), 394-396. [More Information]
- Ninomiya, T., Zoungas, S., Neal, B., Woodward, M., Patel, A., Perkovic, V., Cass, A., Cooper, M., Grobbee, D., Hamet, P., Rodgers, A., MacMahon, S., Chalmers, J., et al (2010). Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trial. Journal of Hypertension, 28(6), 1141-1149. [More Information]
- Batty, G., Li, Q., Czernichow, S., Neal, B., Zoungas, S., Huxley, R., Patel, A., de Galan, B., Woodward, M., Hamet, P., Chalmers, J., et al (2010). Erectile Dysfunction and Later Cardiovascular Disease in Men With Type 2 Diabetes: Prospective Cohort Study Based on the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation) Trial. Journal of the American College of Cardiology, 56(23), 1908-1913. [More Information]
- Patel, A., Neal, B., Chalmers, J. (2010). Event rates in trials of patients with type 2 diabetes. JAMA, 303(8), 732. [More Information]
- Clarke, P., Glasziou, P., Patel, A., Chalmers, J., Woodward, M., Harrap, S., Salomon, J. (2010). Event rates, hospital utilization, and costs associated with major complications of diabetes: a multicountry comparative analysis. PLoS Medicine, 7(2), e1000236-1-e1000236-10. [More Information]
- Brugts, J., Isaacs, A., Boersma, E., van Duijn, C., Uitterlinden, A., Remme, W., Bertrand, M., Ninomiya, T., Ceconi, C., Chalmers, J., MacMahon, S., et al (2010). Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease. European Heart Journal, 31(15), 1854-1864. [More Information]
- Czernichow, S., Ninomiya, T., Huxley, R., Kengne, A., Batty, G., Grobbee, D., Woodward, M., Neal, B., Chalmers, J. (2010). Impact of Blood Pressure Lowering on Cardiovascular Outcomes in Normal Weight, Overweight, and Obese Individuals: The Perindopril Protection Against Recurrent Stroke Study Trial. Hypertension, 55(5), 1193-1198. [More Information]
- Chalmers, J., Arima, H. (2010). Importance of Blood Pressure Lowering in Type 2 Diabetes: Focus on ADVANCE. Journal of Cardiovascular Pharmacology, 55(4), 340-347. [More Information]
- Chalmers, J., Harrap, S., Narkiewicz, K., Poulter, N., Redon, J., Zanchetti, A., Mancia, G. (2010). Issues in the development of new combinations of blood pressure lowering drugs. Journal of Hypertension, 28(12), 2494-2496. [More Information]
- Arima, H., Anderson, C., Wang, J., Huang, Y., Heeley, E., Neal, B., Woodward, M., Skulina, C., Parsons, M., Peng, B., Chalmers, J., et al (2010). Lower Treatment Blood Pressure Is Associated With Greatest Reduction in Hematoma Growth After Acute Intracerebral Hemorrhage. Hypertension, 56, 852-858. [More Information]
- Li, Q., Chalmers, J., Czernichow, S., Neal, B., Taylor, B., Zoungas, S., Poulter, N., Woodward, M., Patel, A., de Galan, B., et al (2010). Oral disease and subsequent cardiovascular disease in people with type 2 diabetes: a prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial. Diabetologia, 53(11), 2320-2327. [More Information]
- Arima, H., Anderson, C., Omae, T., Liu, L., Tzourio, C., Woodward, M., MacMahon, S., Neal, B., Rodgers, A., Chalmers, J. (2010). Perindopril-based blood pressure lowering reduces major vascular events in Asian and Western participants with cerebrovascular disease: the PROGRESS trial. Journal of Hypertension, 28(2), 395-400. [More Information]
- Chalmers, J., Cooper, M., Grobbee, R., Hamet, P., Kengne, A., MacMahon, S., Marre, M., Mogensen, C., Neal, B., Patel, A., et al (2010). Protection against cardiovascular and renal disease in type 2 diabetes: ADVANCEs in the control of blood pressure Peterax and Diamicron MR. In J Chalmers (Eds.), Action in Diabetes and Vascular Disease: Preterax and Diamicron Mr Controlled Evaluation. France: Wolters Kluwer Health France.
- Zoungas, S., Patel, A., Chalmers, J., de Galan, B., Li, Q., Billot, L., Woodward, M., Ninomiya, T., Neal, B., MacMahon, S., Kengne, A., et al (2010). Severe hypoglycemia and risks of vascular events and death. New England Journal of Medicine, 363(15), 1410-1418. [More Information]
- Zoungas, S., Chalmers, J., Kengne, A., Pillai, A., Billot, L., de Galan, B., Marre, M., Neal, B., Harrap, S., Poulter, N., Patel, A. (2010). The efficacy of lowering glycated haemoglobin with a gliclazide modified release-based intensive glucose lowering regimen in the ADVANCE trial. Diabetes Research and Clinical Practice, 89(2), 126-133. [More Information]
- Kengne, A., Patel, A., Colagiuri, S., Heller, S., Hamet, P., Marre, M., Pan, C., Zoungas, S., Grobbee, D., Neal, B., Chalmers, J., Woodward, M. (2010). The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax. Diabetologia, 53(5), 821-831. [More Information]
- Delcourt, C., Huang, Y., Wang, J., Heeley, E., Lindley, R., Stapf, C., Tzourio, C., Arima, H., Parsons, M., Sun, J., Neal, B., Chalmers, J., Anderson, C. (2010). The second (main) phase of an open, randomised, multicentre study to investigate the effectiveness of an intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT2). International Journal of Stroke, 5(2), 110-116. [More Information]
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2009
- Patel, A., Chalmers, J., MacMahon, S., Neal, B. (2009). ADVANCE: Blood Pressure Lowering in Diabetes (Letter to the Editor). Journal of Clinical Hypertension, 11(2), 108-108. [More Information]
- Ninomiya, T., Perkovic, V., de Galan, B., Zoungas, S., Pillai, A., Jardine, M., Patel, A., Cass, A., Neal, B., Poulter, N., Woodward, M., MacMahon, S., Chalmers, J., et al (2009). Albuminuria and Kidney Function Independently Predict Cardiovascular and Renal Outcomes in Diabetes. Journal of the American Society of Nephrology, 20(8), 1813-1821. [More Information]
- Tavakoli, M., Pumford, N., Woodward, M., Doney, A., Chalmers, J., MacMahon, S., MacWalter, R. (2009). An economic evaluation of a perindopril-based blood pressure lowering regimen for patients who have suffered a cerebrovascular event. The European Journal of Health Economics, 10, 111-119. [More Information]
- Kengne, A., Czernichow, S., Huxley, R., Grobbee, D., Woodward, M., Neal, B., Zoungas, S., Cooper, M., Glasziou, P., Hamat, P., Chalmers, J., et al (2009). Blood Pressure Variables and Cardiovascular Risk: New Findings From ADVANCE. Hypertension, 54(2), 399-404. [More Information]
- Zoungas, S., Chalmers, J., Patel, A. (2009). Cardiovascular Risk in Type 2 Diabetes - Reflecting on the ADVANCE Study. European Endocrinology, 5(1), 42-46.
- Zoungas, S., Chalmers, J., Patel, A. (2009). Cardiovascular risk in Type 2 diabetes - reflecting on the ADVANCE study. U S Endocrinology, 5(1), 95-99.
- Zoungas, S., Chalmers, J., Patel, A. (2009). Cardiovascular Risk in Type 2 Diabetes?Reflecting on the ADVANCE Study. U S Endocrinology, 5(1), 95-99.
- de Galan, B., Zoungas, S., Chalmers, J., Anderson, C., Dufouil, C., Pillai, A., Cooper, M., Grobbee, D., Hackett, M., Hamet, P., MacMahon, S., Neal, B., Patel, A., Woodward, M., et al (2009). Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial. Diabetologia, 52(11), 2328-2336. [More Information]
- Ninomiya, T., Donnan, G., Anderson, N., Bladin, C., Chambers, B., Gordon, G., Sharpe, N., Chalmers, J., Woodward, M., Neal, B. (2009). Effects of the end point adjudication process on the results of the Perindopril Protection Against Recurrent Stroke Study (PROGRESS). Stroke, 40(6), 2111-2115. [More Information]
- Czernichow, S., Lee, C., Barzi, F., Greenfield, J., Baur, L., Chalmers, J., Woodward, M., Huxley, R. (2009). Efficacy of weight loss drugs on obesity and cardiovascular risk factors in obese adolescents: a meta-analysis of randomized controlled trials. Obesity Reviews, Online, 1-9. [More Information]
- Turnbull, F., Abraira, C., Anderson, R., Byington, R., Chalmers, J., Duckworth, W., Evans, G., Gerstein, H., Holman, R., Moritz, T., Neal, B., Ninomiya, T., Patel, A., Woodward, M., et al (2009). Intensive glucose control and macrovascular outcomes in type 2 diabetes. Diabetologia, 52(11), 2288-2298. [More Information]
- de Galan, B., Perkovic, V., Ninomiya, T., Pillai, A., Patel, A., Cass, A., Neal, B., Poulter, N., Harrap, S., Mogensen, C., Woodward, M., MacMahon, S., Chalmers, J., et al (2009). Lowering Blood Pressure Reduces Renal Events in Type 2 Diabetes. Journal of the American Society of Nephrology, 20(4), 883-892. [More Information]
- Chalmers, J., Arima, H. (2009). Management of hypertension: evidence from the Blood Pressure Lowering Treatment Trialists' Collaboration and from major clinical trials. Polskie Archiwum Medycyny Wewnetrznej, 119(6), 373-380. [More Information]
- Ninomiya, T., Perkovic, V., Verdon, C., Barzi, F., Cass, A., Gallagher, M., Jardine, M., Anderson, C., Chalmers, J., Craig, J., Huxley, R. (2009). Proteinuria and Stroke: A Meta-analysis of Cohort Studies. American Journal of Kidney Diseases, 53(3), 417-425. [More Information]
- Perkovic, V., Ninomiya, T., MacMahon, S., Chalmers, J. (2009). Renal and microalbuminuria data from ADVANCE. In Bernard I. Levy, Harry A.J. Struijker-Boudier (Eds.), Role of Macro and Microcirculation in Target Organ Damage in Diabetes and Hypertension, (pp. 121-132). West Sussex: Wiley-Blackwell Publishing.
- Du, X., Ninomiya, T., de Galan, B., Abadir, E., Chalmers, J., Pillai, A., Woodward, M., Cooper, M., Harrap, S., Hamet, P., Patel, A., et al (2009). Risks of cardiovascular events and effects of routine blood pressure lowering among patients with type 2 diabetes and atrial fibrillation: results of the ADVANCE study. European Heart Journal, 30, 1128-1135. [More Information]
- Joshi, R., de Galan, B., Chalmers, J., Perkovic, V., Patel, A. (2009). Routine blood pressure lowering and intense glucose control in patients with type 2 diabetes: results from the ADVANCE trial. Expert Review of Endocrinology & Metabolism, 4(2), 111-118. [More Information]
- Dufouil, C., Godin, O., Chalmers, J., Coskun, O., MacMahon, S., Tzourio-Mazoyer, N., Bousser, M., Anderson, C., Mazoyer, B., Tzourio, C. (2009). Severe cerebral white matter hyperintensities predict severe cognitive decline in patients with cerebrovascular disease history. Stroke, 40(6), 2219-2221. [More Information]
- Arima, H., Wang, J., Huang, Y., Heeley, E., Skulina, C., Parsons, M., Peng, B., Li, Q., Su, S., Tao, Q., Chalmers, J., Anderson, C., et al (2009). Significance of perihematomal edema in acute intracerebral hemorrhage: The INTERACT trial. Neurology, 73(23), 1963-1968. [More Information]
- Zoungas, S., de Galan, B., Ninomiya, T., Grobbee, D., Hamet, P., Heller, S., MacMahon, S., Marre, M., Neal, B., Patel, A., Woodward, M., Chalmers, J. (2009). The combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes; new results from ADVANCE. Diabetes Care, 32(11), 2068-2074. [More Information]
- Brugts, J., Ninomiya, T., Boersma, E., Remme, W., Bertrand, M., Ferrari, R., Fox, K., MacMahon, S., Chalmers, J., Simoons, M. (2009). The consistency of the treatment effect of an ACE-inhibitor based treatment regimen in patients with vascular disease or high risk of vascular disease: a combined analysis of individual data of ADVANCE, EUROPA, and PROGRESS trials. European Heart Journal, 30(11), 1385-1394. [More Information]
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2008
- Chalmers, J., Joshi, R., Patel, A. (2008). Advances in reducing the burden of ascular disease in type 2 diabetes. Clinical and Experimental Pharmacology and Physiology, 35, 434-437. [More Information]
- Chockalingham, A., Chalmers, J., Whitworth, J., Erdine, S., Mancia, G., Mendis, S., Heagerty, A. (2008). Antalya statement of the International Society of Hypertension on the prevention of blood pressure-related diseases. Journal of Hypertension, 26, 2255-2258. [More Information]
- Tzourio, C., Arima, H., Harrap, S., Anderson, C., Godin, O., Woodward, M., Neal, B., Bousser, M., Chalmers, J., Cambien, F., MacMahon, S. (2008). APOE genotype, ethnicity, and the risk of cerebral hemorrhage. Neurology, 70(16 (Part 1-2)), 1322-1328. [More Information]
- Welsh, P., Lowe, G., Chalmers, J., Campbell, D., Rumley, A., Neal, B., MacMahon, S., Woodward, M. (2008). Associations of Proinflammatory Cytokines With the Risk of Recurrent Stroke. Stroke, 39, 2226-2230. [More Information]
- Chalmers, J., Joshi, R., Kengne, A., MacMahon, S. (2008). Blood pressure lowering with fixed combination perindopril-indapamide: key findings from ADVANCE. Journal of Hypertension, 26(suppl 2), S11-S15. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2008). Can NT-proBNP Monitoring Help Prevent Cardiovascular Disease? 13th World Congress on Heart Disease, Italy: Medimond International Proceedings.
- Turnbull, F., Woodward, M., Neal, B., Barzi, F., Ninomiya, T., Chalmers, J., Perkovic, V., Li, N., MacMahon, S. (2008). Do men and women respond differently to blood pressure-lowering treatment? Results of prospectively designed overviews of randomized trials. European Heart Journal, 29(21), 2669-2680. [More Information]
- Turnbull, F., Neal, B., Ninomiya, T., Algert, C., Arima, H., Barzi, F., Bulpitt, C., Chalmers, J., Fagard, R., Gleason, A., Heritier, S., Perkovic, V., Woodward, M., MacMahon, S., et al (2008). Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials. BMJ: British Medical Journal, 336(6753), 1121-1123. [More Information]
- Chalmers, J., Joshi, R., Kengne, A., Ninomiya, T., Bi, Y., Bompoint, S., Billot, L., Patel, A. (2008). Efficacy and safety of fixed combination of perindopril and indapamide in type 2 diabetes: results from ADVANCE in context of available evidence. Journal of Hypertension, 26(Suppl 3), S21-S27. [More Information]
- Patel, A., MacMahon, S., Chalmers, J., Neal, B., Billot, L., Woodward, M., Marre, M., Cooper, M., Glasziou, P., Grobbee, D., Joshi, R., et al (2008). Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. New England Journal of Medicine, 358(24), 2560-2572. [More Information]
- Anderson, C., Huang, Y., Wang, J., Arima, H., Neal, B., Peng, B., Heeley, E., Skulina, C., Parsons, M., Jong, S., Heritier, S., Chalmers, J., et al (2008). Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. The Lancet Neurology, 7(5), 391-399. [More Information]
- Patel, A., MacMahon, S., Chalmers, J. (2008). Intensive glucose control in type 2 diabetes - the author's reply. New England Journal of Medicine, 359, 1519-21.
- Chalmers, J., Zhang, J. (2008). Introduction: Advances in the prevention of cardiovascular disease in patients with diabetes. Journal of Hypertension, 26, S1-2. [More Information]
- Ninomiya, T., Perkovic, V., Gallagher, M., Jardine, M., Cass, A., Arima, H., Anderson, C., Neal, B., Woodward, M., Omae, T., MacMahon, S., Chalmers, J. (2008). Lower blood pressure and risk of recurrent stroke in patients with chronic kidney disease: PROGRESS trial. Kidney International, 73(8), 963-970. [More Information]
- Wu, Y., Huxley, R., Li, L., Anna, V., Xie, G., Yao, C., Woodward, M., Li, X., Chalmers, J., Gao, R., et al (2008). Prevalence, Awareness, Treatment, and Control of Hypertension in China: Data from the China National Nutrition and Health Survey 2002. Circulation, 118(25), 2679-2686. [More Information]
- Chalmers, J. (2008). Prevention of stroke and major cardiovascular events with perindopril-based treatment: the PROGRESS trial. In R. Ferrari and K. M. Fox (Eds.), Perindopril: a major contribution to the prevention and treatment of cardiovascular disease, (pp. 47-58). France: Wolters Kluwer Health Pharma Solutions.
- Chalmers, J., Colagiuri, S., Cooper, M., Grobbee, R., Hamet, P., Kengne, A., MacMahon, S., Marre, M., Mogensen, C., Neal, B., Patel, A., Perkovic, V., et al (2008). Prevention of vascular outcomes in type 2 diabetes: benefits of intensive blood pressure and blood glucose control with Preterax and Diamicron MR. France: Wolters Kluwer Health France.
- Patel, A., MacMahon, S., Billot, L., Chalmers, J. (2008). The ADVANCE Trial - the author's reply. The Lancet, 371(9606), 25-26.
- Perkovic, V., Verdon, C., Ninomiya, T., Barzi, F., Cass, A., Patel, A., Jardine, M., Gallagher, M., Turnbull, F., Chalmers, J., Craig, J., Huxley, R. (2008). The relationship between proteinuria and coronary risk: a systematic review and meta-analysis. PLoS Medicine, 5(10), 1486-1495. [More Information]
- Chalmers, J., Cooper, M. (2008). UKPDS and the legacy effect. New England Journal of Medicine, 359(15), 1618-20. [More Information]
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2007
- Chalmers, J. (2007). ADVANCE: New Approaches for the prevention of Vascular Disease in Type 2 Diabetes. Issue 1. France: Wolters Kluwer Health France.
- Turnbull, F., Neal, B., Pfeffer, M., Kostis, J., Algert, C., Woodward, M., Chalmers, J., Zanchetti, A., MacMahon, S. (2007). Blood pressure-dependent and independent effects of agents that inhibit the renin-angiotensin system. Journal of Hypertension, 25(5), 951-958. [More Information]
- Perkovic, V., Ninomiya, T., Arima, H., Jardine, M., Cass, A., Neal, B., MacMahon, S., Chalmers, J. (2007). Chronic Kidney Disease, Cardiovascular Events, and The Effects Of Perindopril-Based Blood Pressure Lowering: Data From The PROGRESS Study. Journal of the American Society of Nephrology, 18(10), 2766-2772. [More Information]
- Patel, A., MacMahon, S., Chalmers, J., Neal, B., Woodward, M., Billot, L., Harrap, S., Poulter, N., Marre, M., Cooper, M., et al (2007). Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. The Lancet, 370(9590), 829-840. [More Information]
- Chalmers, J., Zhang, J. (2007). Introduction. Journal of Hypertension, 25, S1-2. [More Information]
- Campbell, D., Neal, B., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Patel, A., MacMahon, S., Woodward, M. (2007). Low-density lipoprotein particles and risk of intracerebral haemorrhage in subjects with cerebrovascular disease. European Journal of Cardiovascular Prevention and Rehabilitation, 14(3), 413-418. [More Information]
- Chalmers, J., Colagiuri, S., Grobbee, R., Hamet, P., Kengne, A., MacMahon, S., Mogensen, C., Neal, B., Patel, A., Perkovic, V., et al (2007). New approaches for the prevention of vascular disease in type 2 diabetes: benefits of blood pressure lowering with the fixed combination of perindopril and indapamide. France: Wolters Kluwer Health Pharma Solutions.
- Chalmers, J., Kengne, A., Joshi, R., Perkovic, V., Patel, A. (2007). New insights from ADVANCE. Journal of Hypertension, 25(Suppl. 1), S23-S30. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2007). Perindopril-based blood pressure-lowering therapy reduces amino-terminal-pro-B-type natriuretic peptide in subjects with cerebrovascular disease. Journal of Hypertension, 25(3), 699-705. [More Information]
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2006
- Chalmers, J., Perkovic, V., Joshi, R., Patel, A. (2006). ADVANCE: breaking new ground in type 2 diabetes. Journal of Hypertension, 24(Supplement 5), S22-S28. [More Information]
- Perkovic, V., Joshi, R., Patel, A., Bompoint, S., Chalmers, J., Neal, B., MacMahon, S., Glasziou, P., Woodward, M., Cooper, M., et al (2006). ADVANCE: Lessons from the run-in phase of a large study in type 2 diabetes. Blood Pressure, 15(6), 340-346. [More Information]
- Chalmers, J. (2006). Blood pressure and stroke: a continuing debate. Journal of Hypertension, 24(7), 1249-51. [More Information]
- Chalmers, J., Turnbull, F. (2006). Blood Pressure Lowering in Patients with a Previous Stroke. In Mohler E; Townsend R (Eds.), Advanced Therapy in Hypertension and Vascular Disease, (pp. 130-135). Ontario, Canada: BC Decker Inc.
- Gallagher, M., Perkovic, V., Chalmers, J. (2006). Diuretics: A modern day treatment option? (Review Article). Nephrology, 11(5), 419-427. [More Information]
- Arima, H., Chalmers, J., Woodward, M., Anderson, C., Rodgers, A., Davis, S., MacMahon, S., Neal, B., PROGRESS, C. (2006). Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial. Journal of Hypertension, 24(6), 1201-1208. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Patel, A., MacMahon, S. (2006). Perindopril-based blood pressure-lowering therapy reduces amino-terminal-pro-B-type natriuretic peptide levels in subjects with cerebrovascular disease. European Heart Journal, 27(Suppl 1), 781.
- Arima, H., Tzourio, C., Butcher, K., Anderson, C., Bousser, M., Lees, K., Reid, J., Omae, T., Woodward, M., MacMahon, S., Chalmers, J. (2006). Prior Events Predict Cerebrovascular and Coronary Outcomes in the PROGRESS Trial. Stroke, 37(6), 1497-1502. [More Information]
- Arima, H., Chalmers, J. (2006). Secondary prevention of stroke by blood pressure-lowering treatment. Current Hypertension Reports, 8(4), 317-323. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2006). Soluble vascular cell adhesion molecule 1 and N-terminal pro-B-type natriuretic peptide in predicting ischemic stroke in patients with cerebrovascular disease. JAMA Neurology, 63(1), 60-65. [More Information]
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2005
- Chalmers, J., MacMahon, S., Colman, S., Heller, S., Neal, B., Pan, C., Patel, A., Woodward, M., Cooper, M., Adams, M., Fulcher, G., Mitchell, P., Pollock, C., Watson, J., et al (2005). ADVANCE - Action in Diabetes and Vascular Disease: patient recruitment and characteristics of the study population at baseline. Diabetic Medicine, 22(7), 882-888. [More Information]
- Patel, A., Chalmers, J., Poulter, N. (2005). ADVANCE: action in diabetes and vascular disease. Journal of Human Hypertension, 19(Suppl 1), S27-S32. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Neal, B., Patel, A., MacMahon, S. (2005). Amino-terminal pro-B-type natriuretic peptide (NT-proBNP): a risk factor for most seasons. European Heart Journal, 26(Suppl 1), 257.
- Woodward, M., Lowe, G., Campbell, D., Colman, S., Rumley, A., Chalmers, J., Neal, B., Patel, A., Jenkins, A., Kemp, B., MacMahon, S. (2005). Associations of Inflammatory and Hemostatic Variables With the Risk of Recurrent Stroke. Stroke, 36(10), 2143-2147. [More Information]
- Chalmers, J. (2005). Blood pressure in acute stroke: in search of evidence. Journal of Hypertension, 23(2), 277-8. [More Information]
- Dufouil, C., Chalmers, J., Coskun, O., Besancon, V., Bousser, M., Guillon, P., MacMahon, S., Mazoyer, B., Neal, B., Woodward, M., Tzourio, C., et al (2005). Effects of Blood Pressure Lowering on Cerebral White Matter Hyperintensities in Patients With Stroke: The PROGRESS (Perindopril Protection Against Recurrent Stroke Study) Magnetic Resonance Imaging Substudy. Circulation, 112(11), 1644-1650. [More Information]
- Turnbull, F., Neal, B., Algert, C., Chalmers, J., Chapman, N., Cutler, J., Woodward, M., MacMahon, S. (2005). Effects of Different Blood Pressure-Lowering Regimens on Major Cardiovascular Events in Individuals With and Without Diabetes Mellitus: Results of Prospectively Designed Overviews of Randomized Trials. Archives of Internal Medicine, 165(12), 1410-1419. [More Information]
- Carey-Hazell, K., Boyden, A., Rooney, E., Chalmers, J., Jennings, G., Levi, C., Mathew, T., Tonkin, A., Beilby, J., Lowe, M., Lindley, R. (2005). National Health Priority Action Council (NHPAC) (2006), National Service Improvement Framework for Heart, Stroke and Vascular Disease.
- Arima, H., Hart, R., Colman, S., Chalmers, J., Anderson, C., Rodgers, A., Woodward, M., MacMahon, S., Neal, B. (2005). Perindopril-Based Blood Pressure–Lowering Reduces Major Vascular Events in Patients With Atrial Fibrillation and Prior Stroke or Transient Ischemic Attack. Stroke, 36(10), 2164-2169. [More Information]
- Patel, A., Woodward, M., Campbell, D., Sullivan, D., Colman, S., Chalmers, J., Neal, B., MacMahon, S. (2005). Plasma lipids predict myocardial infarction, but not stroke, in patients with established cerebrovascular disease. European Heart Journal, 26(18), 1910-1915. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2005). Prediction of Heart Failure by Amino Terminal-pro-B-Type Natriuretic Peptide and C-Reactive Protein in Subjects With Cerebrovascular Disease. Hypertension, 45(1), 69-74. [More Information]
- Campbell, D., Woodward, M., Chalmers, J., Colman, S., Jenkins, A., Kemp, B., Neal, B., Patel, A., MacMahon, S. (2005). Prediction of Myocardial Infarction by N-Terminal-Pro-B-Type Natriuretic Peptide, C-Reactive Protein, and Renin in Subjects With Cerebrovascular Disease. Circulation, 112(1), 110-116. [More Information]
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2004
- MacMahon, S., Neal, B., Rodgers, A., Chalmers, J. (2004). Commentary: The PROGRESS trial three years later: time for more action, less distraction. BMJ: British Medical Journal, 329(7472), 970-971. [More Information]
- Chalmers, J. (2004). Comparison Of Various Blood Pressure Lowering Treatments on the Primary Prevention of Cardiovascular Outcomes in Recent Randomised Clinical Trials. Clinical and Experimental Hypertension, 26(7-8), 709-719. [More Information]
- Chalmers, J., Chapman, N. (2004). Development Of Blood Pressure Lowering Therapy: From Trials To Practice. In WH Birkenhager, JIS Robertson, A Zanchetti (Eds.), Hypertension in the Twentieth Century: Concepts and Achievements; Handbook of Hypertension, (pp. 504-525). Amsterdam, The Netherlands: Elsevier.
- Chapman, N., Huxley, R., Anderson, C., Bousser, M., Chalmers, J., Colman, S., Davis, S., Donnan, G., MacMahon, S., Neal, B., Woodward, M., et al (2004). Effects of a Perindopril-Based Blood Pressure–Lowering Regimen on the Risk of Recurrent Stroke According to Stroke Subtype and Medical History: The PROGRESS Trial. Stroke, 35(1), 116-121. [More Information]
- Ohkubo, T., Chapman, N., Neal, B., Woodward, M., Omae, T., Chalmers, J., Anderson, C. (2004). Effects of an Angiotensin-converting Enzyme Inhibitor-based Regimen on Pneumonia Risk. American Journal of Respiratory and Critical Care Medicine, 169(9), 1041-1045.
- Hasegawa, Y., Yamaguchi, T., Omae, T., Woodward, M., Chalmers, J. (2004). Effects of Perindopril-Based Blood Pressure Lowering and of Patient Characteristics on the Progression of Silent Brain Infarct: The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) CT Substudy in Japan. Hypertension Research, 27(3), 147-156. [More Information]
- Berthet, K., Neal, B., MacMahon, S., Bousser, M., Colman, S., Woodward, M., Chalmers, J. (2004). Lacunar stroke in PROGRESS study. European Journal of Neurology, 11(Suppl 2), 29.
- Chalmers, J. (2004). Nouvelles Strategies Pour Le Controle De L'Hypertension: Preuves Supplementaries En Faveur Des Associations Faiblement Dosees. (New Strategies For Hypertension Control : More Evidence For Low-Dose Combination Therapy). American Journal of Cardiovascular Drugs, 4(Supplement 1), 37-42. [More Information]
- Rodgers, A., Chapman, N., Woodward, M., Liu, L., Colman, S., Lee, A., Chalmers, J., MacMahon, S., Anderson, C. (2004). Perindopril-based blood pressure lowering in individuals with cerebrovascular disease: consistency of benefits by age, sex and region. Journal of Hypertension, 22(3), 653-659. [More Information]
- Berthet, K., Neal, B., Chalmers, J., MacMahon, S., Bousser, M., Colman, S., Woodward, M., Anderson, C. (2004). Reductions in the Risks of Recurrent Stroke in Patients With and Without Diabetes: The PROGRESS Trial. Blood Pressure, 13(1), 7-13. [More Information]
- Chalmers, J., Morniroli, J. (2004). The Kidney and Hypertension in Diabetes Mellitus. In Carl Erik Mogensen (Eds.), Blood Pressure Lowering Treatment And The Prevention Of Stroke In The Diabetic Patient, (pp. 611-630). London: Taylor and Francis.
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2003
- MacMahon, S., Chalmers, J. (2003). Blood pressure lowering and ACE inhibition for the avoidance of cardiac and cerebral events. European Heart Journal, 24(5), 391-393. [More Information]
- Patel, A., Chalmers, J., Chaturvedi, V., Currie, R., Monaghan, H., Neal, B. (2003). Diabetes and vascular disease: a new international trial. Asian Cardiovascular and Thoracic Annals, 11(2), 180-184. [More Information]
- Chaturvedi, V., Patel, A., Chalmers, J., Chapman, N., Hansson, L., MacMahon, S., Mancia, G., Neal, B., Reid, J., Sharpe, N., Woodward, M., Anderson, C., et al (2003). Effects of a perindopril-based blood pressure lowering regimen on cardiac outcomes among patients with cerebrovascular disease. European Heart Journal, 24(5), 475-484. [More Information]
- Fransen, M., Anderson, C., Chalmers, J., Chapman, N., Davis, S., MacMahon, S., Neal, B., Sega, R., Terent, A., Tzourio, C., Woodward, M. (2003). Effects of a Perindopril-Based Blood Pressure-Lowering Regimen on Disability and Dependency in 6105 Patients With Cerebrovascular Disease: A Randomized Controlled Trial. Stroke, 34(10), 2333-2338. [More Information]
- Tzourio, C., Anderson, C., Chapman, N., Woodward, M., Neal, B., MacMahon, S., Chalmers, J., Lindley, R. (2003). Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Archives of Internal Medicine, 163(9), 1069-1075. [More Information]
- Turnbull, F., Neal, B., Algert, C., Chalmers, J., Woodward, M., MacMahon, S. (2003). Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomized trials. The Lancet, 362(9395), 1527-1535. [More Information]
- Chalmers, J. (2003). Etude ADVANCE: objectifs, protocole et etat actuel. Drugs, 63(Special Issue 1), 39-44.
- Chalmers, J., Todd, A., Chapman, N., Beilin, L., Davis, S., Donnan, G., Frommer, M., Huxley, R., Lenfant, C., MacMahon, S., et al (2003). International Society of hypertension (ISH): Statement on blood pressure lowering and stroke prevention. Journal of Hypertension, 21(4), 651-663. [More Information]
- Bath, P., Chalmers, J., Powers, W., Lawrie, B., Davis, S., Lenfant, C., Mancia, G., Neal, B., Whitworth, J., Zanchetti, A. (2003). International society of hypertension (ISH): Statement on the management of blood pressure in acute stroke. Journal of Hypertension, 21(4), 665-672. [More Information]
- Chalmers, J., Arnolda, L. (2003). Lowering blood pressure in 2003. Medical Journal of Australia, 179(6), 306-312.
- Ward, M., Bishop, J., Theile, D., Chalmers, J., Cass, A. (2003). Options for Clinical Services.
- Chalmers, J., MacMahon, S. (2003). Perindopril Protection Against Recurrent Stroke Study (PROGRESS) : Interpretation and implementation. Journal of Hypertension, 21(Suppl 5), S9-S14.
- Chalmers, J., MacMahon, S., Currie, R. (2003). PROGRESS: Rationale, results and importance: Perspective from the Principle Investigators. In Teruo Omae (Eds.), How to conduct large-scaled clinical trials in Japan, (pp. 51-55). Japan: Nihon Iji Shinpo.
- Harrap, S., Tzourio, C., Cambien, F., Poirier, O., Raoux, S., Chalmers, J., Chapman, N., Colman, S., Leguennec, S., MacMahon, S., Neal, B., Ohkubo, T., Woodward, M., Anderson, C. (2003). The ACE Gene I/D Polymorphism Is Not Associated With the Blood Pressure and Cardiovascular Benefits of ACE Inhibition. Hypertension, 42(3), 297-303. [More Information]
- Chapman, N., Chalmers, J. (2003). The prevention of secondary stroke, cardiac outcomes and cognitive decline in patients with cerebrovascular disease: The PROGRESS Trial. Seminars In Cerebrovascualr Diseases and Stroke, 3(3), 171-180.
- Chalmers, J. (2003). Trials on blood pressure-lowering and secondary stroke prevention. American Journal of Cardiology, 91(10A), 3G-8G. [More Information]
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2002
- Chalmers, J., MacMahon, S., Brass, L., Chapman, N., Gorelick, P., Neal, B. (2002). Clinician's Manual on Blood Pressure and Stroke Prevention. United Kingdom: Current Medicine Group Ltd.
- Chalmers, J. (2002). Enhancing risk stratification in hypertensive subjects: how far should we go in routine screening for target organ damage? Journal of Hypertension, 20(7), 1255-1257. [More Information]
- Freedman, B., Brieger, D., Celermajer, D., Chalmers, J., Tofler, G., Campbell, T., Feneley, M., Marwick, T., Muller, D., Tonkin, A. (2002). Global cardiology comes to Australia: 14th World Congress of Cardiology, Sydney, 5-9 May 2002. Medical Journal of Australia, 177(9), 473-475. [More Information]
- Chalmers, J. (2002). The ABCD of anti-hypertensive therapy? Journal of Hypertension, 20(4), 615-616. [More Information]
- Chalmers, J. (2002). Treating Hypertension or Lowering Blood Pressure? Extending the Concept. Blood Pressure, 11(2), 68-70. [More Information]
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2001
- Chalmers, J., Whitworth, J. (2001). A half-century of Australian health and medical research. Medical Journal of Australia, 174, 29-32.
- Neal, B., Chapman, J., Chalmers, J., MacMahon, S., Girgis, S., Patel, A. (2001). Blood pressure and the vascular complications of diabetes. Medicographia, 23(3), 214-219.
- Chalmers, J., Neal, B., Chapman, J., MacMahon, S., Patel, A., Girgis, S. (2001). Blood pressure lowering in diabetes: a brief review of the current evidence and description of a new trial. Clinical and Experimental Pharmacology and Physiology, 28, 1108-1111. [More Information]
- Goodchild, A., Sun, Q., Chalmers, J., Pilowsky, P., Llewellyn-Smith, I., Cunningham, A. (2001). Calbindin-Ummunoreactive neurons in the reticular formation of the rat brainstem: catecholamine content and spinal projections. Journal of Comparative Neurology, 424, 547-562.
- Chalmers, J., Chapman, J. (2001). Challenges for the prevention of primary and secondary stroke: the importance of lowering blood pressure and total cardiovascular risk. Blood Pressure, 10, 344-351.
- Goodchild, A., Chalmers, J., Pilowsky, P., Phillips, J., Dubey, R., Sesiashvili, E., Takeda, M., Lipski,, J. (2001). Differential expression of catecholamine biosynthetic enzymes in the rat ventrolateral medulla. Journal of Comparative Neurology, 431, 20-34. [More Information]
- Chalmers, J. (2001). Ongoing trials of angiotensin-converting enzyme inhibition: what they can tell us. American Journal of Hypertension, 14.
- Chalmers, J., Chapman, J. (2001). Progress in reducing the burden of stroke. Clinical and Experimental Pharmacology and Physiology, 28, 1091-1095. [More Information]
- MacMahon, S., Neal, B., Woodward, M., Chalmers, J., Tzourio, C., Rodgers, A., Cutler, J., Ohkubo,, T., Lindley, R., Anderson, C. (2001). Randomised trail of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. The Lancet, 358, 1033-1041. [More Information]
- Chalmers, J., MacMahon, S., Neal, B., Girgis, S., Patel, A. (2001). Rationale and design of the ADVANCE study: a randomised trial of blood pressure lowering and intensive glucose control in high-risk individuals with type 2 diabetes mellitus. Journal of Hypertension, 19 (suppl 4).
- MacMahon, S., Rodgers, A., Neal, B., Woodward, M., Chalmers, J. (2001). REPLY: The lowering of blood pressure after stroke. The Lancet, 358(9297), 1994-1995.
- Chalmers, J., MacMahon, S., Neal, B., Ferrannini, E., Girgis, S., Patel, A. (2001). Study rationale and design of ADVANCE: Action in diabetes and vascular disease - preterax and diamicron MR controlled evaluation. Diabetologia, 44, 1118-1120.
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Selected Grants
2016
- Apps to improve medication adherence in Coronary Heart Disease (MedApp-CHD) Study, Redfern J, Santo K, Chow C, Chalmers J, National Heart Foundation of Australia/Vanguard Grant
2013
- Discovery and translation of evidence for new strategies to combat cardiovascular diseases, MacMahon S, Chalmers J, Neal B, Woodward M, Anderson C, Patel A, Rodgers A, Perkovic V, National Health and Medical Research Council (NHMRC)/Program Grants
2011
- Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED), Anderson C, Chalmers J, Lindley R, Arima H, Wang J, Levi C, National Health and Medical Research Council (NHMRC)/Project Grants
2009
- Reducing Salt in the Australian Diet, Neal B, Nowson C, Chalmers J, Smith W, Flood V, Nowson, C, Woodward M, Szabo L, National Health and Medical Research Council (NHMRC)/Partnership Projects
- Using health economics to strengthen ties between evidence, policy and practice in chronic disease, Jan S, Clarke P, Howard K, Salkeld G, Chalmers J, Leeder S, National Health and Medical Research Council (NHMRC)/Strategic Awards: Capacity Building Grants for Health Services Research
2008
- Generating the evidence for new strategies to combat cardiovascular diseases., MacMahon S, Chalmers J, Neal B, Woodward M, Anderson C, Patel A, National Health and Medical Research Council (NHMRC)/Program Grants
2007
- INTERACT: a randomised trial of intensive blood pressure lowering in acute intracerebral haermorrhage, Anderson C, Wang J, Chalmers J, Wang J, Lindley R, National Health and Medical Research Council (NHMRC)/Project Grants
2004
- New evidence to guide decisions about the prevention and treatment of common cardiovascular diseases, Croft K, MacMahon S, Chalmers J, Neal B, Anderson C, Woodward M, Croft K, National Health and Medical Research Council (NHMRC)/Program Grants
2002
- The blood pressure lowering treatment trialists collaboration, Chalmers J, Chapman N, MacMahon S, Neal B, Woodward M, National Health and Medical Research Council (NHMRC)/Project Grants
2001
- Internal Research Support Chalmers - CHS, Chalmers J, University of Sydney/Internal Research Grant Allocations - Medicine
- A factorial randomised trial of intensive blood pressure lowering and glucose control in subjects with type 2 diabetes, Chalmers J, MacMahon S, Neal B, Woodward M, National Health and Medical Research Council (NHMRC)/Clinical Trial Large Scale (CTLS)
2000
- WHO-ISH BP blood pressure lowering treatment trialists collaboration, Chalmers J, MacMahon S, Neal B, National Health and Medical Research Council (NHMRC)/Project Grants
1999
- Servier Clinical Trial Agreement (including variation to the agreement between the Uni of Syd, ADIR & The Institut de Recherches Int Servier), Dowell G, Kramer D, MacMahon S, MacMahon S, Monaghan H, Pracy M, Sowden K, Chalmers J, Servier/Research Grants
- Functional specificity of bulbospinal pathways regulating blood pressure, Pilowsky P, Chalmers J, National Health and Medical Research Council (NHMRC)/Project Grants
- Central inhibitory neurons in experimental hypertension, Pilowsky P, Chalmers J, Goodchild A, National Heart Foundation of Australia/Grants-in-Aid
- WHO-ISH blood pressure lowering treatment trialists collaboration, Chalmers J, MacMahon S, Neal B, National Heart Foundation of Australia/Grants-in-Aid
1998
- NHMRC 990846 MacMahon , Chalmers J, MacMahon S, Neal B, National Health and Medical Research Council (NHMRC)/Project Grants
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