People_

Dr Julia Steinberg

Genomics and Precision Health Stream Lead
The Daffodil Centre

Email

julia.steinberg@sydney.edu.au

Websites

Genomics and Precision Health research stream

Google scholar profile

Biographical details

A/Prof Julia Steinberg is a Cancer Institute NSW Career Development Fellow and leads the Genomics and Precision Health research stream. Her research programme aims to integrate individual and population-level genomic, sociodemographic, medical, and behaviour information for successful precision health. Julia’s focus is on effectively and sustainably improving human health and reducing the burden of cancer.

Research interests

Genetics, Genomics, Precision Health, Population Health, Epidemiology, Risk prediction, Analyses of large-scale data, Risk-based screening, Multi-cancer early detection tests

Current projects

Julia co-leads the Australian Cancer Risk Study on genomic risk prediction and risk-tailored screening and early detection for four common cancers (breast, prostate, melanoma, and colorectal). This multidisciplinary collaborative program aims to

generate new genomic data on over 7,400 participants of the 45 and Up Study, including over 5,000 participants diagnosed with cancer;
develop and evaluate genomic and integrative risk tools for the Australian population;
identify public preferences related to genomic risk prediction and risk-tailored cancer screening and early detection;
determine potential effective and cost-effective genomics-informed risk-tailored screening and early detection strategies, leveraging the extensive Policy1 mathematical modelling platform.

Julia's Career Development Fellowship builds on this work to further investigate the potential of genomics-informed risk prediction to improve outcomes for prostate cancer, with a particular focus on aggressive disease.

Julia also leads a new collaborative program of work to evaluate the potential of multi-cancer early detection tests in Australia (funded for 2025-2030). This program brings together researchers from several Australian and international institutions, health professionals, and consumers to

provide an ongoing landscape and horizon scan of existing and emerging MCED tests;
map potential pathways for MCED test use and subsequent clinical follow-up investigations in Australia, establishing alignment with needs and preferences of health professionals and consumers;
assess the benefits, harms, and cost implications of various potential MCED testing scenarios in Australia, developing a dynamic, flexible evaluation platform to rapidly integrate new evidence;
formulate a policy and practice Roadmap for future MCED test evaluation and (if/when evidence thresholds are met) pathways to evidence-based implementation in Australia.

Themes

Cancer

Keywords

Cancer, Epidemiology, Public health, Genomics, Precision health

Approaches

Epidemiology, Genetics, Risk Factors/Risk Assessment

Current research students

Project title	Research student
Investigating the potential of genomics-informed risk prediction to improve early detection for common cancers in Australia	Philip LY
Melanoma risk assessment and risk-stratified melanoma screening and surveillance with a focus on skin imaging technologies	Gillian REYES-MARCELINO

Publications

By Type

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Journals

Rahman, M., David, M., Steinberg, J., Cust, A., Yu, X., Rutherford, C., Banks, E., Byles, J., Canfell, K. (2025). Association of optimism and social support with health-related quality of life among Australian women cancer survivors - A cohort study. Asia-Pacific Journal of Clinical Oncology, 21(2), 221-231. [More Information]
Yap, S., David, M., Steinberg, J., Luo, Q., Wade, S., Ngo, P., Goldsbury, D., Sarich, P., Banks, E., Weber, M., Canfell, K. (2024). Impact of weighting on the association between sociodemographic characteristics, health behaviours and cancer, cardiovascular and all-cause mortality in the Australian 45 and Up Study. Cancer Epidemiology, 90, 102567. [More Information]
Goldsbury, D., Haywood, P., Pearce, A., Karikios, D., Canfell, K., Steinberg, J., Weber, M. (2024). Out-of-pocket health care expenses for people with and without cancer, New South Wales, 2020: a cross-sectional study. Medical Journal of Australia. [More Information]
Luo, Q., Steinberg, J., Kahn, C., Caruana, M., Grogan, P., Page, A., Ivers, R., Banks, E., O'Connell, D., Canfell, K. (2024). Trends and projections of cause-specific premature mortality in Australia to 2044: a statistical modelling study. The Lancet Regional Health. Western Pacific, 43. [More Information]
Velentzis, L., Freeman, V., Campbell, D., Hughes, S., Luo, Q., Steinberg, J., Egger, S., Mann, G., Nickson, C. (2023). Breast Cancer Risk Assessment Tools for Stratifying Women into Risk Groups: A Systematic Review. Cancers, 15(4). [More Information]
Yap, S., He, E., Egger, S., Goldsbury, D., Lew, J., Ngo, P., Worthington, J., Rillstone, H., Zalcberg, J., Cuff, J., Ward, R., Canfell, K., Feletto, E., Steinberg, J. (2023). Colon and rectal cancer treatment patterns and their associations with clinical, sociodemographic and lifestyle characteristics: analysis of the Australian 45 and Up Study cohort. BMC Cancer, 23(1). [More Information]
Allen, C., Turbitt, E., Rahm, A., Saylor, K., Best, S., Hatch, A., Santangelo, I., Roberts, M., Olstad, D., Kahkoska, A., Steinberg, J., et al (2023). Extending an Antiracism Lens to the Implementation of Precision Public Health Interventions. American Journal of Public Health, 113(11), 1210-1218. [More Information]
Cheng, E., Velentzis, L., Weber, M., Steinberg, J., Canfell, K., Yu, X. (2023). Female reproductive and hormonal factors and lung cancer mortality among never-smokers: A prospective cohort study of 287 408 Chinese women. International Journal of Cancer, 152(12), 2528-2540. [More Information]
Goldsbury, D., Vassallo, A., Weber, M., Steinberg, J., Webb, P., deFazio, A., Canfell, K. (2023). Health services costs for ovarian cancer in Australia: Estimates from the 45 and Up Study. PloS One, 18(4 April). [More Information]
Young, M., Yanes, T., Cust, A., Dunlop, K., Limb, S., Newson, A., Purvis, R., Thiyagarajan, L., Scott, R., Verma, K., Steinberg, J., et al (2023). Human Genetics Society of Australasia Position Statement: Use of Polygenic Scores in Clinical Practice and Population Health. Twin Research and Human Genetics. [More Information]
Morrow, A., Steinberg, J., Chan, P., Tiernan, G., Kennedy, E., Egoroff, N., Hilton, D., Sankey, L., Venchiarutti, R., Pearn, A., et al (2023). In person and virtual process mapping experiences to capture and explore variability in clinical practice: application to genetic referral pathways across seven Australian hospital networks. Translational Behavioral Medicine. [More Information]
Yap, S., Vassallo, A., Goldsbury, D., O'Connell, D., Brand, A., Emery, J., deFazio, A., Canfell, K., Steinberg, J. (2023). Pathways to diagnosis of endometrial and ovarian cancer in the 45 and Up Study cohort. Cancer Causes and Control, 34(1), 47-58. [More Information]
O’Haire, S., Franchini, F., Kang, Y., Steinberg, J., Canfell, K., Desai, J., Fox, S., IJzerman, M. (2023). Systematic review of NTRK 1/2/3 fusion prevalence pan-cancer and across solid tumours. Scientific Reports, 13(1). [More Information]
Dawson, G., Bleicher, K., Baynes, S., D’Este, C., Steinberg, J., Weber, M., Newby, J., Ding, D., Liu, B., Edwards, B., et al (2022). 45 and up COVID Insights: a dynamic and collaborative approach to evidence-making during the COVID-19 pandemic. Public Health Research and Practice, 32(4). [More Information]
Katsoula, G., Steinberg, J., Tuerlings, M., Coutinho de Almeida, R., Southam, L., Swift, D., Meulenbelt, I., Wilkinson, J., Zeggini, E. (2022). A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis. Human Molecular Genetics, 31(12), 2090-2105. [More Information]
Kang, Y., O’Haire, S., Franchini, F., IJzerman, M., Zalcberg, J., MacRae, F., Canfell, K., Steinberg, J. (2022). A scoping review and meta-analysis on the prevalence of pan-tumour biomarkers (dMMR, MSI, high TMB) in different solid tumours. Scientific Reports, 12(1). [More Information]
Yap, S., Vassallo, A., Goldsbury, D., Salagame, U., Velentzis, L., Banks, E., O'Connell, D., Canfell, K., Steinberg, J. (2022). Accurate categorisation of menopausal status for research studies: a step-by-step guide and detailed algorithm considering age, self-reported menopause and factors potentially masking the occurrence of menopause. BMC Research Notes, 15(1), 88. [More Information]
Feletto, E., Kohar, A., Mizrahi, D., Grogan, P., Steinberg, J., Hughes, C., Watson, W., Canfell, K., Yu, X. (2022). An ecological study of obesity-related cancer incidence trends in Australia from 1983 to 2017. The Lancet Regional Health. Western Pacific, 29. [More Information]
Kreitmaier, P., Suderman, M., Southam, L., Coutinho de Almeida, R., Hatzikotoulas, K., Meulenbelt, I., Steinberg, J., Relton, C., Wilkinson, J., Zeggini, E. (2022). An epigenome-wide view of osteoarthritis in primary tissues. American Journal of Human Genetics, 109(7), 1255-1271. [More Information]
Freeman, V., Hughes, S., Carle, C., Campbell, D., Egger, S., Hui, H., Yap, S., Deandrea, S., Caruana, M., Onyeka, T., O'Connell, D., Steinberg, J., Canfell, K., et al (2022). Are patients with cancer at higher risk of COVID-19-related death? A systematic review and critical appraisal of the early evidence. Journal of Cancer Policy, 33. [More Information]
Morrow, A., Chan, P., Tiernan, G., Steinberg, J., Debono, D., Wolfenden, L., Tucker, K., Hogden, E., Taylor, N. (2022). Building capacity from within: Qualitative evaluation of a training program aimed at upskilling healthcare workers in delivering an evidence-based implementation approach. Translational Behavioral Medicine, 12(1), 39-62. [More Information]
Luo, Q., O'Connell, D., Yu, X., Kahn, C., Caruana, M., Pesola, F., Sasieni, P., Grogan, P., Aranda, S., Cabasag, C., Steinberg, J., Canfell, K., et al (2022). Cancer incidence and mortality in Australia from 2020 to 2044 and an exploratory analysis of the potential effect of treatment delays during the COVID-19 pandemic: a statistical modelling study. The Lancet Public Health, 7(6), e537-e548. [More Information]
Weber, M., Ngo, P., Banks, E., Steinberg, J., Goldsbury, D., Grogan, P., Canfell, K. (2022). Capacity of the 45 and up Study to mobilise evidence-based improvements in cancer control: lung cancer case study. Public Health Research and Practice, 32(4). [More Information]
Cheng, E., Weber, M., Steinberg, J., Canfell, K., Yu, X. (2022). Evaluating risk factors for lung cancer among never-smoking individuals using two Australian studies. Journal of Cancer Research and Clinical Oncology, 148(10), 2827-2840. [More Information]
Nair-Shalliker, V., Bang, S., Egger, S., Yu, X., Chiam, K., Steinberg, J., Patel, M., Banks, E., O'Connell, D., Armstrong, B., Smith, D. (2022). Family history, obesity, urological factors and diabetic medications and their associations with risk of prostate cancer diagnosis in a large prospective study. British Journal of Cancer, 127(4), 735-746. [More Information]
Steinberg, J., Iles, M., Lee, J., Wang, X., Law, M., Smit, A., Nguyen-Dumont, T., Giles, G., Southey, M., Milne, R., Cust, A., et al (2022). Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts*. British Journal of Dermatology, 186(5), 823-834. [More Information]
Steinberg, J., Chan, P., Hogden, E., Tiernan, G., Morrow, A., Kang, Y., He, E., Venchiarutti, R., Titterton, L., Sankey, L., Mckay, S., Engel, A., Kench, J., Solomon, M., Toh, J., Canfell, K., et al (2022). Lynch syndrome testing of colorectal cancer patients in a high-income country with universal healthcare: a retrospective study of current practice and gaps in seven australian hospitals. Hereditary Cancer in Clinical Practice, 20(1), 18. [More Information]
Luo, Q., Steinberg, J., Yu, X., Weber, M., Caruana, M., Yap, S., Grogan, P., Banks, E., O'Connell, D., Canfell, K. (2022). Projections of smoking-related cancer mortality in Australia to 2044. Journal of Epidemiology and Community Health, 76(9), 792-799. [More Information]
Yap, S., Luo, Q., Wade, S., Weber, M., Banks, E., Canfell, K., O'Connell, D., Steinberg, J. (2022). Raking of data from a large Australian cohort study improves generalisability of estimates of prevalence of health and behaviour characteristics and cancer incidence. BMC Medical Research Methodology, 22(1), 140. [More Information]
Cheng, E., Chan, K., Weber, M., Steinberg, J., Young, J., Canfell, K., Yu, X. (2022). Solid Fuel, Secondhand Smoke, and Lung Cancer Mortality A Prospective Cohort of 323,794 Chinese Never-Smokers. American Journal of Respiratory and Critical Care Medicine, 206(9), 1153-1162. [More Information]
Carle, C., Hughes, S., Freeman, V., Campbell, D., Egger, S., Caruana, M., Hui, H., Yap, S., Deandrea, S., Onyeka, T., O'Connell, D., Canfell, K., Steinberg, J., et al (2022). The risk of contracting SARS-CoV-2 or developing COVID-19 for people with cancer: A systematic review of the early evidence. Journal of Cancer Policy, 33. [More Information]
Sarich, P., Cabasag, C., Liebermann, E., Vaneckova, P., Carle, C., Hughes, S., Egger, S., O'Connell, D., Weber, M., da Costa, A., Caruana, M., Canfell, K., Steinberg, J., et al (2022). Tobacco smoking changes during the first pre-vaccination phases of the COVID-19 pandemic: A systematic review and meta-analysis. EClinicalMedicine, 47. [More Information]
Luo, Q., Lew, J., Steinberg, J., Worthington, J., Yu, X., Caruana, M., Soerjomataram, I., Bray, F., Lawrance, S., Arcorace, M., O'Connell, D., Canfell, K., Feletto, E. (2022). Trends in colon and rectal cancer mortality in Australia from 1972 to 2015 and associated projections to 2040. Scientific Reports, 12(1), 3994. [More Information]
Steinberg, J., Southam, L., Roumeliotis, T., Clark, M., Jayasuriya, R., Swift, D., Shah, K., Butterfield, N., Brooks, R., McCaskie, A., et al (2021). A molecular quantitative trait locus map for osteoarthritis. Nature Communications, 12(1), 1309. [More Information]
Butterfield, N., Curry, K., Steinberg, J., Dewhurst, H., Komla-Ebri, D., Mannan, N., Adoum, A., Leitch, V., Logan, J., Waung, J., et al (2021). Accelerating functional gene discovery in osteoarthritis. Nature Communications, 12(1), 467. [More Information]
Boer, C., Hatzikotoulas, K., Southam, L., Stefánsdóttir, L., Zhang, Y., Coutinho de Almeida, R., Wu, T., Zheng, J., Hartley, A., Teder-Laving, M., Steinberg, J., et al (2021). Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell, 184(18), 4784-4.82E+20. [More Information]
Goldsbury, D., Feletto, E., Weber, M., Haywood, P., Pearce, A., Lew, J., Worthington, J., He, E., Steinberg, J., O'Connell, D., Canfell, K. (2021). Health system costs and days in hospital for colorectal cancer patients in New South Wales, Australia. PloS One, 16(11-Nov), e0260088. [More Information]
Luo, Q., Steinberg, J., Yu, X., Caruana, M., Canfell, K., O'Connell, D. (2021). How Well Have Projected Lung Cancer Rates Predicted the Actual Observed Rates? Asian Pacific Journal of Cancer Prevention, 22(2), 437-445. [More Information]
Steinberg, J., Yap, S., Goldsbury, D., Nair-Shalliker, V., Banks, E., Canfell, K., O’Connell, D. (2021). Large-scale systematic analysis of exposure to multiple cancer risk factors and the associations between exposure patterns and cancer incidence. Scientific Reports, 11(1), 2343. [More Information]
Steinberg, J., Southam, L., Fontalis, A., Clark, M., Jayasuriya, R., Swift, D., Shah, K., Brooks, R., McCaskie, A., Wilkinson, J., et al (2021). Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis. Annals of the Rheumatic Diseases, 80(8), 1070-1074. [More Information]
Cheng, E., Egger, S., Hughes, S., Weber, M., Steinberg, J., Rahman, B., Worth, H., Ruano-Ravina, A., Rawstorne, P., Yu, X. (2021). Systematic review and meta-analysis of residential radon and lung cancer in never-smokers. European Respiratory Review, 30(159), 1-14. [More Information]
Luo, Q., Steinberg, J., O’Connell, D., Grogan, P., Canfell, K., Feletto, E. (2020). Changes in cancer incidence and mortality in Australia over the period 1996–2015. BMC Research Notes, 13(1), 561. [More Information]
Simms, K., Steinberg, J., Caruana, M., Smith, M., Lew, J., Soerjomataram, I., Castle, P., Bray, F., Canfell, K. (2019). Impact of scaled up human papillomavirus vaccination and cervical screening and the potential for global elimination of cervical cancer in 181 countries, 2020–99: a modelling study. The Lancet Oncology, 20(3), 394-407. [More Information]
Simms, K., Steinberg, J., Caruana, M., Smith, M., Lew, J., Soerjomataram, I., Castle, P., Bray, F., Canfell, K. (2019). Towards global elimination of cervical cancer in all groups of women - Authors' reply. The Lancet Oncology, 20(5), e239. [More Information]
Casalone, E., Tachmazidou, I., Zengini, E., Hatzikotoulas, K., Hackinger, S., Suveges, D., Steinberg, J., Rayner, N., Wilkinson, J., Panoutsopoulou, K., et al (2018). A novel variant in GLIS3 is associated with osteoarthritis. Annals of the Rheumatic Diseases, 77(4), 620-623. [More Information]
Zengini, E., Hatzikotoulas, K., Tachmazidou, I., Steinberg, J., Hartwig, F., Southam, L., Hackinger, S., Boer, C., Styrkarsdottir, U., Gilly, A., et al (2018). Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics, 50(4), 549-558. [More Information]
Hatzikotoulas, K., Roposch, A., Wainwright, A., Theologis, T., Clarke, N., Dwyer, J., Hashemi-Nejad, A., Kiely, N., Katchburian, M., Nicolaou, N., et al (2018). Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5. Communications Biology, 1(1), 56. [More Information]
Huckins, L., Hatzikotoulas, K., Southam, L., Thornton, L., Steinberg, J., Aguilera-Mckay, F., Treasure, J., Schmidt, U., Gunasinghe, C., Romero, A., et al (2018). Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. Molecular Psychiatry, 23(5), 1169-1180. [More Information]
Steinberg, J., Brooks, R., Southam, L., Bhatnagar, S., Roumeliotis, T., Hatzikotoulas, K., Zengini, E., Mark Wilkinson, J., Choudhary, J., McCaskie, A., et al (2018). Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology, 57(8), 1481-1489. [More Information]
Steinberg, J., Shah, K., Gartland, A., Zeggini, E., Wilkinson, J. (2017). Effects of chronic cobalt and chromium exposure after metal-on-metal hip resurfacing: An epigenome-wide association pilot study. Journal of Orthopaedic Research, 35(10), 2323-2328. [More Information]
Hackinger, S., Trajanoska, K., Styrkarsdottir, U., Zengini, E., Steinberg, J., Ritchie, G., Hatzikotoulas, K., Gilly, A., Evangelou, E., Kemp, J., et al (2017). Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus. Human Molecular Genetics, 26(19), 3850-3858. [More Information]
Steinberg, J., Ritchie, G., Roumeliotis, T., Jayasuriya, R., Clark, M., Brooks, R., Binch, A., Shah, K., Coyle, R., Pardo, M., et al (2017). Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis. Scientific Reports, 7(1), 8935. [More Information]
Tachmazidou, I., Süveges, D., Min, J., Ritchie, G., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., et al (2017). Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. American Journal of Human Genetics, 100(6), 865-884. [More Information]
Steinberg, J., Zeggini, E. (2016). Functional genomics in osteoarthritis: Past, present, and future. Journal of Orthopaedic Research, 34(7), 1105-1110. [More Information]
Taylor, A., Steinberg, J., Webber, C. (2015). Duplications in ADHD patients harbour neurobehavioural genes that are co-expressed with genes associated with hyperactivity in the mouse. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 168(2), 97-107. [More Information]
Andrews, T., Meader, S., Vulto-van Silfhout, A., Taylor, A., Steinberg, J., Hehir-Kwa, J., Pfundt, R., de Leeuw, N., de Vries, B., Webber, C. (2015). Gene Networks Underlying Convergent and Pleiotropic Phenotypes in a Large and Systematically-Phenotyped Cohort with Heterogeneous Developmental Disorders. PLoS Genetics, 11(3), e1005012. [More Information]
Taylor, A., Steinberg, J., Andrews, T., Webber, C. (2015). GeneNet Toolbox for MATLAB: A flexible platform for the analysis of gene connectivity in biological networks. Bioinformatics, 31(3), 442-444. [More Information]
Steinberg, J., Honti, F., Meader, S., Webber, C. (2015). Haploinsufficiency predictions without study bias. Nucleic Acids Research, 43(15), 474. [More Information]
Ferry, Q., Steinberg, J., Webber, C., FitzPatrick, D., Ponting, C., Zisserman, A., Nellåker, C. (2014). Diagnostically relevant facial gestalt information from ordinary photos. eLife, 2014 (3), e02020. [More Information]
Popadin, K., Gutierrez-Arcelus, M., Lappalainen, T., Buil, A., Steinberg, J., Nikolaev, S., Lukowski, S., Bazykin, G., Seplyarskiy, V., Ioannidis, P., et al (2014). Gene age predicts the strength of purifying selection acting on gene expression variation in humans. American Journal of Human Genetics, 95(6), 660-674. [More Information]
Akpudo, H., Aleksic, B., Alkelai, A., Burton, C., Carillo Roa, T., Chen, D., Cheng, M., Cocchi, E., Davis, L., Giori, I., et al (2014). Summaries of oral sessions at the XXI World Congress of Psychiatric Genetics, Boston, Massachusetts, 17-21 October 2013: State of the field. Psychiatric Genetics, 24(4), 125-150. [More Information]

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By Year

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2025

Rahman, M., David, M., Steinberg, J., Cust, A., Yu, X., Rutherford, C., Banks, E., Byles, J., Canfell, K. (2025). Association of optimism and social support with health-related quality of life among Australian women cancer survivors - A cohort study. Asia-Pacific Journal of Clinical Oncology, 21(2), 221-231. [More Information]

2024

Yap, S., David, M., Steinberg, J., Luo, Q., Wade, S., Ngo, P., Goldsbury, D., Sarich, P., Banks, E., Weber, M., Canfell, K. (2024). Impact of weighting on the association between sociodemographic characteristics, health behaviours and cancer, cardiovascular and all-cause mortality in the Australian 45 and Up Study. Cancer Epidemiology, 90, 102567. [More Information]
Goldsbury, D., Haywood, P., Pearce, A., Karikios, D., Canfell, K., Steinberg, J., Weber, M. (2024). Out-of-pocket health care expenses for people with and without cancer, New South Wales, 2020: a cross-sectional study. Medical Journal of Australia. [More Information]
Luo, Q., Steinberg, J., Kahn, C., Caruana, M., Grogan, P., Page, A., Ivers, R., Banks, E., O'Connell, D., Canfell, K. (2024). Trends and projections of cause-specific premature mortality in Australia to 2044: a statistical modelling study. The Lancet Regional Health. Western Pacific, 43. [More Information]

2023

Velentzis, L., Freeman, V., Campbell, D., Hughes, S., Luo, Q., Steinberg, J., Egger, S., Mann, G., Nickson, C. (2023). Breast Cancer Risk Assessment Tools for Stratifying Women into Risk Groups: A Systematic Review. Cancers, 15(4). [More Information]
Yap, S., He, E., Egger, S., Goldsbury, D., Lew, J., Ngo, P., Worthington, J., Rillstone, H., Zalcberg, J., Cuff, J., Ward, R., Canfell, K., Feletto, E., Steinberg, J. (2023). Colon and rectal cancer treatment patterns and their associations with clinical, sociodemographic and lifestyle characteristics: analysis of the Australian 45 and Up Study cohort. BMC Cancer, 23(1). [More Information]
Allen, C., Turbitt, E., Rahm, A., Saylor, K., Best, S., Hatch, A., Santangelo, I., Roberts, M., Olstad, D., Kahkoska, A., Steinberg, J., et al (2023). Extending an Antiracism Lens to the Implementation of Precision Public Health Interventions. American Journal of Public Health, 113(11), 1210-1218. [More Information]
Cheng, E., Velentzis, L., Weber, M., Steinberg, J., Canfell, K., Yu, X. (2023). Female reproductive and hormonal factors and lung cancer mortality among never-smokers: A prospective cohort study of 287 408 Chinese women. International Journal of Cancer, 152(12), 2528-2540. [More Information]
Goldsbury, D., Vassallo, A., Weber, M., Steinberg, J., Webb, P., deFazio, A., Canfell, K. (2023). Health services costs for ovarian cancer in Australia: Estimates from the 45 and Up Study. PloS One, 18(4 April). [More Information]
Young, M., Yanes, T., Cust, A., Dunlop, K., Limb, S., Newson, A., Purvis, R., Thiyagarajan, L., Scott, R., Verma, K., Steinberg, J., et al (2023). Human Genetics Society of Australasia Position Statement: Use of Polygenic Scores in Clinical Practice and Population Health. Twin Research and Human Genetics. [More Information]
Morrow, A., Steinberg, J., Chan, P., Tiernan, G., Kennedy, E., Egoroff, N., Hilton, D., Sankey, L., Venchiarutti, R., Pearn, A., et al (2023). In person and virtual process mapping experiences to capture and explore variability in clinical practice: application to genetic referral pathways across seven Australian hospital networks. Translational Behavioral Medicine. [More Information]
Yap, S., Vassallo, A., Goldsbury, D., O'Connell, D., Brand, A., Emery, J., deFazio, A., Canfell, K., Steinberg, J. (2023). Pathways to diagnosis of endometrial and ovarian cancer in the 45 and Up Study cohort. Cancer Causes and Control, 34(1), 47-58. [More Information]
O’Haire, S., Franchini, F., Kang, Y., Steinberg, J., Canfell, K., Desai, J., Fox, S., IJzerman, M. (2023). Systematic review of NTRK 1/2/3 fusion prevalence pan-cancer and across solid tumours. Scientific Reports, 13(1). [More Information]

show 6 more

2022

Dawson, G., Bleicher, K., Baynes, S., D’Este, C., Steinberg, J., Weber, M., Newby, J., Ding, D., Liu, B., Edwards, B., et al (2022). 45 and up COVID Insights: a dynamic and collaborative approach to evidence-making during the COVID-19 pandemic. Public Health Research and Practice, 32(4). [More Information]
Katsoula, G., Steinberg, J., Tuerlings, M., Coutinho de Almeida, R., Southam, L., Swift, D., Meulenbelt, I., Wilkinson, J., Zeggini, E. (2022). A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis. Human Molecular Genetics, 31(12), 2090-2105. [More Information]
Kang, Y., O’Haire, S., Franchini, F., IJzerman, M., Zalcberg, J., MacRae, F., Canfell, K., Steinberg, J. (2022). A scoping review and meta-analysis on the prevalence of pan-tumour biomarkers (dMMR, MSI, high TMB) in different solid tumours. Scientific Reports, 12(1). [More Information]
Yap, S., Vassallo, A., Goldsbury, D., Salagame, U., Velentzis, L., Banks, E., O'Connell, D., Canfell, K., Steinberg, J. (2022). Accurate categorisation of menopausal status for research studies: a step-by-step guide and detailed algorithm considering age, self-reported menopause and factors potentially masking the occurrence of menopause. BMC Research Notes, 15(1), 88. [More Information]
Feletto, E., Kohar, A., Mizrahi, D., Grogan, P., Steinberg, J., Hughes, C., Watson, W., Canfell, K., Yu, X. (2022). An ecological study of obesity-related cancer incidence trends in Australia from 1983 to 2017. The Lancet Regional Health. Western Pacific, 29. [More Information]
Kreitmaier, P., Suderman, M., Southam, L., Coutinho de Almeida, R., Hatzikotoulas, K., Meulenbelt, I., Steinberg, J., Relton, C., Wilkinson, J., Zeggini, E. (2022). An epigenome-wide view of osteoarthritis in primary tissues. American Journal of Human Genetics, 109(7), 1255-1271. [More Information]
Freeman, V., Hughes, S., Carle, C., Campbell, D., Egger, S., Hui, H., Yap, S., Deandrea, S., Caruana, M., Onyeka, T., O'Connell, D., Steinberg, J., Canfell, K., et al (2022). Are patients with cancer at higher risk of COVID-19-related death? A systematic review and critical appraisal of the early evidence. Journal of Cancer Policy, 33. [More Information]
Morrow, A., Chan, P., Tiernan, G., Steinberg, J., Debono, D., Wolfenden, L., Tucker, K., Hogden, E., Taylor, N. (2022). Building capacity from within: Qualitative evaluation of a training program aimed at upskilling healthcare workers in delivering an evidence-based implementation approach. Translational Behavioral Medicine, 12(1), 39-62. [More Information]
Luo, Q., O'Connell, D., Yu, X., Kahn, C., Caruana, M., Pesola, F., Sasieni, P., Grogan, P., Aranda, S., Cabasag, C., Steinberg, J., Canfell, K., et al (2022). Cancer incidence and mortality in Australia from 2020 to 2044 and an exploratory analysis of the potential effect of treatment delays during the COVID-19 pandemic: a statistical modelling study. The Lancet Public Health, 7(6), e537-e548. [More Information]
Weber, M., Ngo, P., Banks, E., Steinberg, J., Goldsbury, D., Grogan, P., Canfell, K. (2022). Capacity of the 45 and up Study to mobilise evidence-based improvements in cancer control: lung cancer case study. Public Health Research and Practice, 32(4). [More Information]
Cheng, E., Weber, M., Steinberg, J., Canfell, K., Yu, X. (2022). Evaluating risk factors for lung cancer among never-smoking individuals using two Australian studies. Journal of Cancer Research and Clinical Oncology, 148(10), 2827-2840. [More Information]
Nair-Shalliker, V., Bang, S., Egger, S., Yu, X., Chiam, K., Steinberg, J., Patel, M., Banks, E., O'Connell, D., Armstrong, B., Smith, D. (2022). Family history, obesity, urological factors and diabetic medications and their associations with risk of prostate cancer diagnosis in a large prospective study. British Journal of Cancer, 127(4), 735-746. [More Information]
Steinberg, J., Iles, M., Lee, J., Wang, X., Law, M., Smit, A., Nguyen-Dumont, T., Giles, G., Southey, M., Milne, R., Cust, A., et al (2022). Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts*. British Journal of Dermatology, 186(5), 823-834. [More Information]
Steinberg, J., Chan, P., Hogden, E., Tiernan, G., Morrow, A., Kang, Y., He, E., Venchiarutti, R., Titterton, L., Sankey, L., Mckay, S., Engel, A., Kench, J., Solomon, M., Toh, J., Canfell, K., et al (2022). Lynch syndrome testing of colorectal cancer patients in a high-income country with universal healthcare: a retrospective study of current practice and gaps in seven australian hospitals. Hereditary Cancer in Clinical Practice, 20(1), 18. [More Information]
Luo, Q., Steinberg, J., Yu, X., Weber, M., Caruana, M., Yap, S., Grogan, P., Banks, E., O'Connell, D., Canfell, K. (2022). Projections of smoking-related cancer mortality in Australia to 2044. Journal of Epidemiology and Community Health, 76(9), 792-799. [More Information]
Yap, S., Luo, Q., Wade, S., Weber, M., Banks, E., Canfell, K., O'Connell, D., Steinberg, J. (2022). Raking of data from a large Australian cohort study improves generalisability of estimates of prevalence of health and behaviour characteristics and cancer incidence. BMC Medical Research Methodology, 22(1), 140. [More Information]
Cheng, E., Chan, K., Weber, M., Steinberg, J., Young, J., Canfell, K., Yu, X. (2022). Solid Fuel, Secondhand Smoke, and Lung Cancer Mortality A Prospective Cohort of 323,794 Chinese Never-Smokers. American Journal of Respiratory and Critical Care Medicine, 206(9), 1153-1162. [More Information]
Carle, C., Hughes, S., Freeman, V., Campbell, D., Egger, S., Caruana, M., Hui, H., Yap, S., Deandrea, S., Onyeka, T., O'Connell, D., Canfell, K., Steinberg, J., et al (2022). The risk of contracting SARS-CoV-2 or developing COVID-19 for people with cancer: A systematic review of the early evidence. Journal of Cancer Policy, 33. [More Information]
Sarich, P., Cabasag, C., Liebermann, E., Vaneckova, P., Carle, C., Hughes, S., Egger, S., O'Connell, D., Weber, M., da Costa, A., Caruana, M., Canfell, K., Steinberg, J., et al (2022). Tobacco smoking changes during the first pre-vaccination phases of the COVID-19 pandemic: A systematic review and meta-analysis. EClinicalMedicine, 47. [More Information]
Luo, Q., Lew, J., Steinberg, J., Worthington, J., Yu, X., Caruana, M., Soerjomataram, I., Bray, F., Lawrance, S., Arcorace, M., O'Connell, D., Canfell, K., Feletto, E. (2022). Trends in colon and rectal cancer mortality in Australia from 1972 to 2015 and associated projections to 2040. Scientific Reports, 12(1), 3994. [More Information]

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2021

Steinberg, J., Southam, L., Roumeliotis, T., Clark, M., Jayasuriya, R., Swift, D., Shah, K., Butterfield, N., Brooks, R., McCaskie, A., et al (2021). A molecular quantitative trait locus map for osteoarthritis. Nature Communications, 12(1), 1309. [More Information]
Butterfield, N., Curry, K., Steinberg, J., Dewhurst, H., Komla-Ebri, D., Mannan, N., Adoum, A., Leitch, V., Logan, J., Waung, J., et al (2021). Accelerating functional gene discovery in osteoarthritis. Nature Communications, 12(1), 467. [More Information]
Boer, C., Hatzikotoulas, K., Southam, L., Stefánsdóttir, L., Zhang, Y., Coutinho de Almeida, R., Wu, T., Zheng, J., Hartley, A., Teder-Laving, M., Steinberg, J., et al (2021). Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell, 184(18), 4784-4.82E+20. [More Information]
Goldsbury, D., Feletto, E., Weber, M., Haywood, P., Pearce, A., Lew, J., Worthington, J., He, E., Steinberg, J., O'Connell, D., Canfell, K. (2021). Health system costs and days in hospital for colorectal cancer patients in New South Wales, Australia. PloS One, 16(11-Nov), e0260088. [More Information]
Luo, Q., Steinberg, J., Yu, X., Caruana, M., Canfell, K., O'Connell, D. (2021). How Well Have Projected Lung Cancer Rates Predicted the Actual Observed Rates? Asian Pacific Journal of Cancer Prevention, 22(2), 437-445. [More Information]
Steinberg, J., Yap, S., Goldsbury, D., Nair-Shalliker, V., Banks, E., Canfell, K., O’Connell, D. (2021). Large-scale systematic analysis of exposure to multiple cancer risk factors and the associations between exposure patterns and cancer incidence. Scientific Reports, 11(1), 2343. [More Information]
Steinberg, J., Southam, L., Fontalis, A., Clark, M., Jayasuriya, R., Swift, D., Shah, K., Brooks, R., McCaskie, A., Wilkinson, J., et al (2021). Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis. Annals of the Rheumatic Diseases, 80(8), 1070-1074. [More Information]
Cheng, E., Egger, S., Hughes, S., Weber, M., Steinberg, J., Rahman, B., Worth, H., Ruano-Ravina, A., Rawstorne, P., Yu, X. (2021). Systematic review and meta-analysis of residential radon and lung cancer in never-smokers. European Respiratory Review, 30(159), 1-14. [More Information]

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2020

Luo, Q., Steinberg, J., O’Connell, D., Grogan, P., Canfell, K., Feletto, E. (2020). Changes in cancer incidence and mortality in Australia over the period 1996–2015. BMC Research Notes, 13(1), 561. [More Information]

2019

Simms, K., Steinberg, J., Caruana, M., Smith, M., Lew, J., Soerjomataram, I., Castle, P., Bray, F., Canfell, K. (2019). Impact of scaled up human papillomavirus vaccination and cervical screening and the potential for global elimination of cervical cancer in 181 countries, 2020–99: a modelling study. The Lancet Oncology, 20(3), 394-407. [More Information]
Simms, K., Steinberg, J., Caruana, M., Smith, M., Lew, J., Soerjomataram, I., Castle, P., Bray, F., Canfell, K. (2019). Towards global elimination of cervical cancer in all groups of women - Authors' reply. The Lancet Oncology, 20(5), e239. [More Information]

2018

Casalone, E., Tachmazidou, I., Zengini, E., Hatzikotoulas, K., Hackinger, S., Suveges, D., Steinberg, J., Rayner, N., Wilkinson, J., Panoutsopoulou, K., et al (2018). A novel variant in GLIS3 is associated with osteoarthritis. Annals of the Rheumatic Diseases, 77(4), 620-623. [More Information]
Zengini, E., Hatzikotoulas, K., Tachmazidou, I., Steinberg, J., Hartwig, F., Southam, L., Hackinger, S., Boer, C., Styrkarsdottir, U., Gilly, A., et al (2018). Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics, 50(4), 549-558. [More Information]
Hatzikotoulas, K., Roposch, A., Wainwright, A., Theologis, T., Clarke, N., Dwyer, J., Hashemi-Nejad, A., Kiely, N., Katchburian, M., Nicolaou, N., et al (2018). Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5. Communications Biology, 1(1), 56. [More Information]
Huckins, L., Hatzikotoulas, K., Southam, L., Thornton, L., Steinberg, J., Aguilera-Mckay, F., Treasure, J., Schmidt, U., Gunasinghe, C., Romero, A., et al (2018). Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. Molecular Psychiatry, 23(5), 1169-1180. [More Information]
Steinberg, J., Brooks, R., Southam, L., Bhatnagar, S., Roumeliotis, T., Hatzikotoulas, K., Zengini, E., Mark Wilkinson, J., Choudhary, J., McCaskie, A., et al (2018). Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology, 57(8), 1481-1489. [More Information]

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2017

Steinberg, J., Shah, K., Gartland, A., Zeggini, E., Wilkinson, J. (2017). Effects of chronic cobalt and chromium exposure after metal-on-metal hip resurfacing: An epigenome-wide association pilot study. Journal of Orthopaedic Research, 35(10), 2323-2328. [More Information]
Hackinger, S., Trajanoska, K., Styrkarsdottir, U., Zengini, E., Steinberg, J., Ritchie, G., Hatzikotoulas, K., Gilly, A., Evangelou, E., Kemp, J., et al (2017). Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus. Human Molecular Genetics, 26(19), 3850-3858. [More Information]
Steinberg, J., Ritchie, G., Roumeliotis, T., Jayasuriya, R., Clark, M., Brooks, R., Binch, A., Shah, K., Coyle, R., Pardo, M., et al (2017). Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis. Scientific Reports, 7(1), 8935. [More Information]
Tachmazidou, I., Süveges, D., Min, J., Ritchie, G., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., et al (2017). Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. American Journal of Human Genetics, 100(6), 865-884. [More Information]

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2016

Steinberg, J., Zeggini, E. (2016). Functional genomics in osteoarthritis: Past, present, and future. Journal of Orthopaedic Research, 34(7), 1105-1110. [More Information]

2015

Taylor, A., Steinberg, J., Webber, C. (2015). Duplications in ADHD patients harbour neurobehavioural genes that are co-expressed with genes associated with hyperactivity in the mouse. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 168(2), 97-107. [More Information]
Andrews, T., Meader, S., Vulto-van Silfhout, A., Taylor, A., Steinberg, J., Hehir-Kwa, J., Pfundt, R., de Leeuw, N., de Vries, B., Webber, C. (2015). Gene Networks Underlying Convergent and Pleiotropic Phenotypes in a Large and Systematically-Phenotyped Cohort with Heterogeneous Developmental Disorders. PLoS Genetics, 11(3), e1005012. [More Information]
Taylor, A., Steinberg, J., Andrews, T., Webber, C. (2015). GeneNet Toolbox for MATLAB: A flexible platform for the analysis of gene connectivity in biological networks. Bioinformatics, 31(3), 442-444. [More Information]
Steinberg, J., Honti, F., Meader, S., Webber, C. (2015). Haploinsufficiency predictions without study bias. Nucleic Acids Research, 43(15), 474. [More Information]

show 1 more

2014

Ferry, Q., Steinberg, J., Webber, C., FitzPatrick, D., Ponting, C., Zisserman, A., Nellåker, C. (2014). Diagnostically relevant facial gestalt information from ordinary photos. eLife, 2014 (3), e02020. [More Information]
Popadin, K., Gutierrez-Arcelus, M., Lappalainen, T., Buil, A., Steinberg, J., Nikolaev, S., Lukowski, S., Bazykin, G., Seplyarskiy, V., Ioannidis, P., et al (2014). Gene age predicts the strength of purifying selection acting on gene expression variation in humans. American Journal of Human Genetics, 95(6), 660-674. [More Information]
Akpudo, H., Aleksic, B., Alkelai, A., Burton, C., Carillo Roa, T., Chen, D., Cheng, M., Cocchi, E., Davis, L., Giori, I., et al (2014). Summaries of oral sessions at the XXI World Congress of Psychiatric Genetics, Boston, Massachusetts, 17-21 October 2013: State of the field. Psychiatric Genetics, 24(4), 125-150. [More Information]

Selected Grants

2023

Leveraging genomic risk tools to improve early detection and outcomes for prostatecancer, Steinberg J, Cancer Institute NSW/Career Development Fellowship
PRECISE (Practitioner Readiness, Education and Capabilities, with Implementation Science Evaluation) Genomics Research Project, Ma A, Steinberg J, Barnett S, Wilkinson D, Monrouxe L, Cust A, Makeham M, Jamieson R, Smit A, Rankin N, Jones K, Dunlop K, Sawleshwarkar S, Bonner C, Boggs K, Department of Health and Aged Care (Federal - administered by NHMRC)/Genomics Health Futures Mission - 2022 MRFF Genomics Health Futures Mission

2021

Genomic risk prediction and risk-tailored screening and early detection for common cancers, Cust A, Steinberg J, Canfell K, Pearce A, Keefe D, MacArthur D, Caruana M, Bilkey G, McNamara M, Wray N, Martin N, MacInnis R, Department of Health and Aged Care (Federal)/MRFF - Genomic Health Futures Mission (GHFM) - Genomics Health Futures Mission Grant

2020

Modelling five-year patterns in cancer incidence, staging and related health services, Canfell K, Feletto E, Weber M, Caruana M, Haywood P, Pearce A, Fong K, Goldsbury D, Procopio P, Steinberg J, Department of Health and Aged Care (Federal)/MRFF - Preventive and Public Health Research - Targeted Health System & Community Organisation