People_
Dr Julian Ayer
Senior Lecturer
Paediatrics & Child Health, Children's Hospital, Westmead
Paediatrics & Child Health, Children's Hospital, Westmead
Details
Member of the Charles Perkins Centre
Early life origins of atherosclerosis Obesity and cardiovascular disease Outcomes research in congenital heart disease Cardiac MRI
Potential student projects
Effects of left heart obstruction on ventricular mechanics
Ventricular-ventricular interactions in structural heart disease
Exercise training and cardiac rehabilitation
Early life intervnetions to reduced cardiovascular disease
Congenital heart disease Echocardiography Cardiac MRI
Obesity, Diabetes and Cardiovascular Disease, Reproductive, Maternal and Child Health, Lifespan
Project title | Research student |
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Exercise for children and adults living with moderate and complex congenital heart disease: adaptations barriers and interventions | Sally GOSBELL |
Publications
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Book Chapters
- Mosalman Haghighi, M., Ayer, J. (2018). Cardiovascular Assessment in Human Research. In Paul C. Guest (Eds.), Methods in Molecular Biology, vol. 1735: Investigations of Early Nutrition Effects on Long-Term Health, (pp. 297-310). New York: Humana Press. [More Information]
Journals
- Fitzgerald, N., Adams, P., Mervis, J., Webb, A., Roberts, P., Ayer, J. (2024). A Comparison of Ductal Stenting and Surgical Shunts for Infants with Duct-Dependent Pulmonary Blood Flow: The Impact of Single Versus Biventricular Repair Pathways on Outcomes. Pediatric Cardiology. [More Information]
- Sholler, G., Donovan, S., Eastaugh, L., Elliott, C., Fletcher, J., Justo, R., Kasparian, N., Kelly, A., Morsman, D., Nicolae, M., Orr, Y., Ayer, J., Cordina, R., et al (2024). Australian National Standards of Care for Childhood-onset Heart Disease (CoHD Standards). 1st Edition. Heart, Lung, and Circulation. [More Information]
- Verrall, C., Tran, D., Kasparian, N., Williams, T., Oxenham, V., Ayer, J., Celermajer, D., Cordina, R. (2024). Cognitive Functioning and Psychosocial Outcomes in Adults with Complex Congenital Heart Disease: A Cross-sectional Pilot Study. Pediatric Cardiology. [More Information]
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2024
- Fitzgerald, N., Adams, P., Mervis, J., Webb, A., Roberts, P., Ayer, J. (2024). A Comparison of Ductal Stenting and Surgical Shunts for Infants with Duct-Dependent Pulmonary Blood Flow: The Impact of Single Versus Biventricular Repair Pathways on Outcomes. Pediatric Cardiology. [More Information]
- Sholler, G., Donovan, S., Eastaugh, L., Elliott, C., Fletcher, J., Justo, R., Kasparian, N., Kelly, A., Morsman, D., Nicolae, M., Orr, Y., Ayer, J., Cordina, R., et al (2024). Australian National Standards of Care for Childhood-onset Heart Disease (CoHD Standards). 1st Edition. Heart, Lung, and Circulation. [More Information]
- Verrall, C., Tran, D., Kasparian, N., Williams, T., Oxenham, V., Ayer, J., Celermajer, D., Cordina, R. (2024). Cognitive Functioning and Psychosocial Outcomes in Adults with Complex Congenital Heart Disease: A Cross-sectional Pilot Study. Pediatric Cardiology. [More Information]
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2023
- King, G., Buratto, E., Cordina, R., Iyengar, A., Grigg, L., Kelly, A., Bullock, A., Ayer, J., Alphonso, N., d'Udekem, Y., et al (2023). Atrioventricular septal defect in Fontan circulation: Right ventricular dominance, not valve surgery, adversely affects survival. Journal of Thoracic and Cardiovascular Surgery, 165(2), 424-433. [More Information]
- Davidson, H., Zannino, D., D'udekem, Y., Cordina, R., Orr, Y., Konstantinov, I., G.Weintraub, R., Wheaton, G., Saundankar, J., Salve, G., Ayer, J., et al (2023). Does leaving native antegrade pulmonary blood flow at the time of the superior cavopulmonary connection impact long-term outcomes after the Fontan? JTCVS Open, 16, 825-835. [More Information]
- Verrall, C., Tran, D., Yang, J., Lubans, D., Winlaw, D., Ayer, J., Celermajer, D., Cordina, R. (2023). Exercise as therapy for neurodevelopmental and cognitive dysfunction in people with a Fontan circulation: A narrative review. Frontiers in Pediatrics, 11. [More Information]
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2022
- Verrall, C., Chen, J., Yeh, C., Mackay, M., D'udekem, Y., Winlaw, D., Iyengar, A., Ayer, J., Gentles, T., Cordina, R., et al (2022). A diffusion MRI study of brain white matter microstructure in adolescents and adults with a Fontan circulation: Investigating associations with resting and peak exercise oxygen saturations and cognition. NeuroImage: Clinical, 36. [More Information]
- Payne, E., Wilson, T., Mosalman Haghighi, M., McCallum, Z., D’udekem, Y., Ayer, J. (2022). Associations between Bodyweight and Clinical Outcome in Patients Post-Fontan Procedure: A Systematic Review. Congenital Heart Disease, 17(6), 617-639. [More Information]
- Payne, E., Garden, F., D’udekem, Y., McCallum, Z., Wightman, H., Zannino, D., Zentner, D., Cordina, R., Weintraub, R., Wilson, T., Ayer, J. (2022). Body Mass Index Trajectory and Outcome Post Fontan Procedure. Journal of the American Heart Association, 11(18). [More Information]
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2021
- Cai, T., Mosalman Haghighi, M., Roberts, P., Mervis, J., Qasem, A., Butlin, M., Celermajer, D., Avolio, A., Skilton, M., Ayer, J. (2021). Assessment of Central Arterial Hemodynamics in Children: Comparison of Noninvasive and Invasive Measurements. American Journal of Hypertension, 34(2), 163-171. [More Information]
- Puranik, R., Tann, O., Occleshaw, C., Celermajer, D., Grigg, L., Bullock, A., Chen, S., Ugander, M., Cordina, R., Ayer, J. (2021). CMRI in Congenital Heart Disease Patients: Concerns Over Patient Safety Because of Inadequate Accreditation Procedures for MRI Scanning and Reporting. Heart, Lung, and Circulation, 30(8), e86-e87. [More Information]
- Cao, J., Tran, D., Briody, J., Attard, C., Hassan, E., Simm, P., Burchill, L., Twigg, S., Fiatarone Singh, M., Ayer, J., Celermajer, D., Cordina, R., et al (2021). Impact of adiposity on clinical outcomes in people living with a Fontan circulation. International Journal of Cardiology, 329, 82-88. [More Information]
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2020
- Tran, D., D'Ambrosio, P., Verrall, C., Attard, C., Briody, J., D'Souza, M., Fiatarone Singh, M., Ayer, J., d'Udekem, Y., Twigg, S., Davis, G., Celermajer, D., Cordina, R. (2020). Body Composition in Young Adults Living With a Fontan Circulation: The Myopenic Profile. Journal of the American Heart Association, 9, 1-15. [More Information]
- Cai, T., Qasem, A., Butlin, M., Aviolo, A., Ayer, J., Celermajer, D., Skilton, M. (2020). Effect of body habitus and heart rate on accuracy of aortic-radial transfer functions for predicting central hemodynamic indices in growing children. Artery Research, 26(4), 242-249. [More Information]
- Ebrahimi, P., Youssef, D., Salve, G., Ayer, J., Dehghani, F., Fletcher, D., Winlaw, D. (2020). Evaluation of personalized right ventricle to pulmonary artery conduits using in silico design and computational analysis of flow. JTCVS Open, 1(C), 33-48. [More Information]
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2019
- Lester, G., Femia, J., Ayer, J., Puranik, R. (2019). A case report: X-linked dystrophin gene mutation causing severe isolated dilated cardiomyopathy. European Heart Journal - Case Reports, 3(2), 1-5. [More Information]
- Lawley, C., Popat, H., Wong, M., Badawi, N., Ayer, J. (2019). A Dramatic Response to Sirolimus Therapy in a Premature Infant With Massive Cardiac Rhabdomyoma. JACC: Case Reports, 1(3), 327-331. [More Information]
- King, G., Ayer, J., Celermajer, D., Zentner, D., Justo, R., Disney, P., Zannino, D., d’Udekem, Y. (2019). Atrioventricular Valve Failure in Fontan Palliation. Journal of the American College of Cardiology, 73(7), 810-822. [More Information]
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2018
- Mosalman Haghighi, M., Ayer, J. (2018). Cardiovascular Assessment in Human Research. In Paul C. Guest (Eds.), Methods in Molecular Biology, vol. 1735: Investigations of Early Nutrition Effects on Long-Term Health, (pp. 297-310). New York: Humana Press. [More Information]
- Chong, L., Fitzgerald, D., Craig, J., Manera, K., Hanson, C., Celermajer, D., Ayer, J., Kasparian, N., Jaure, A. (2018). Children's experiences of congenital heart disease: a systematic review of qualitative studies. European Journal of Pediatrics, 177(3), 319-336. [More Information]
- Garden, F., Toelle, B., Mihrshahi, S., Webb, K., Almqvist, C., Tovey, E., Brew, B., Ayer, J., Skilton, M., Jones, G., Cowie, C., Britton, W., Celermajer, D., Leeder, S., Peat, J., Marks, G., et al (2018). Cohort profile: The Childhood Asthma Prevention Study (CAPS). International Journal of Epidemiology, 47(6), 1736a-1736k. [More Information]
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2017
- Cai, T., Qasem, A., Ayer, J., Butlin, M., O'Meagher, S., Melki, C., Marks, G., Avolio, A., Celermajer, D., Skilton, M. (2017). Central blood pressure in children and adolescents: non-invasive development and testing of novel transfer functions. Journal of Human Hypertension, 31(12), 831-837. [More Information]
- Marathe, S., Jones, M., Ayer, J., Sun, J., Orr, Y., Verrall, C., Nicholson, I., Chard, R., Sholler, G., Winlaw, D. (2017). Congenitally corrected transposition: Complex anatomic repair or Fontan pathway? Asian Cardiovascular and Thoracic Annals, 25(6), 432-439. [More Information]
- Franken, L., Admiraal, M., Verrall, C., Zannino, D., Ayer, J., Iyengar, A., Cole, A., Sholler, G., d'Udekem, Y., Winlaw, D. (2017). Improved long-term outcomes in double-inlet left ventricle and tricuspid atresia with transposed great arteries: systemic outflow tract obstruction present at birth defines long-term outcome. European Journal Of Cardio-Thoracic Surgery, 51(6), 1051-1057. [More Information]
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2016
- Cai, T., Sullivan, T., Ayer, J., Harmer, J., Leeder, S., Toelle, B., Marks, G., Celermajer, D., Skilton, M. (2016). Carotid extramedial thickness is associated with local arterial stiffness in children. Journal of Hypertension, 34(1), 109-115. [More Information]
- Gnanappa, G., Laohachai, K., Orr, Y., Ayer, J. (2016). Isolated Anomalous Origin of Left Pulmonary Artery From the Descending Aorta: An Embryologic Ambiguity. Annals of Thoracic Surgery, 102(5), e439-e441. [More Information]
- Skilton, M., Nakhla, S., Ayer, J., Harmer, J., Toelle, B., Leeder, S., Jones, G., Marks, G., Celermajer, D. (2016). Telomere length in early childhood: Early life risk factors and association with carotid intima-media thickness in later childhood. European Journal of Preventive Cardiology, 23(10), 1086-1092. [More Information]
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2015
- Ayer, J., Charakida, M., Deanfield, J., Celermajer, D. (2015). Lifetime risk: childhood obesity and cardiovascular risk. European Heart Journal, 36(22), 1371-1376. [More Information]
2014
- Skilton, M., Sullivan, T., Ayer, J., Garden, F., Harmer, J., Leeder, S., Toelle, B., Webb, K., Marks, G., Celermajer, D. (2014). Weight gain in infancy is associated with carotid extra-medial thickness in later childhood. Atherosclerosis, 233(2), 370-374. [More Information]
2013
- Lau, E., Morgan, P., Belousova, E., Toelle, B., Ayer, J., Celermajer, D., Marks, G. (2013). Asymmetric dimethylarginine and asthma: results from the Childhood Asthma Prevention Study. European Respiratory Journal, 41(5), 1234-1237. [More Information]
- Skilton, M., Marks, G., Ayer, J., Garden, F., Garnett, S., Harmer, J., Leeder, S., Toelle, B., Webb, K., Baur, L., Celermajer, D. (2013). Weight gain in infancy and vascular risk factors in later childhood. Pediatrics, 131(6), e1821-e1828. [More Information]
2012
- Ayer, J., Sholler, G. (2012). Cardiovascular risk factors in Australian children: Hypertension and lipid abnormalities. Australian Prescriber, 35(2), 51-55. [More Information]
- Skilton, M., Sullivan, T., Ayer, J., Harmer, J., Toelle, B., Webb, K., Marks, G., Celermajer, D. (2012). Carotid extra-medial thickness in childhood: Early life effects on the arterial adventitia. Atherosclerosis, 222(2), 478-482. [More Information]
- Skilton, M., Ayer, J., Harmer, J., Webb, K., Leeder, S., Marks, G., Celermajer, D. (2012). Impaired Fetal Growth and Arterial Wall Thickening: A Randomized Trial of Omega-3 Supplementation. Pediatrics, 129(3), e698-e703. [More Information]
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2011
- Ayer, J., Belousova, E., Harmer, J., David, C., Marks, G., Celermajer, D. (2011). Maternal cigarette smoking is associated with reduced high-density lipoprotein cholesterol in healthy 8-year-old children. European Heart Journal, 32(19), 2446-2453. [More Information]
- Marshall, N., Ayer, J., Toelle, B., Harmer, J., Phillips, C., Grunstein, R., Celermajer, D., Marks, G. (2011). Snoring is not associated with adverse effects on blood pressure, arterial structure or function in 8-year-old children: The Childhood Asthma Prevention Study (CAPS). Journal of Paediatrics and Child Health, 47(8), 518-523. [More Information]
2010
- Ayer, J., Song, C., Steinbeck, K., Celermajer, D., Freedman, B. (2010). Increased Tissue Factor Activity in Monocytes from Obese Young Adults. Clinical and Experimental Pharmacology and Physiology, 37(11), 1049-1054. [More Information]
- Ayer, J., Sholler, G., Celermajer, D. (2010). Left atrial size increases with body mass index in children. International Journal of Cardiology, 141(1), 61-67. [More Information]
2009
- Ayer, J., Harmer, J., Xuan, W., Toelle, B., Webb, K., Almqvist, C., Marks, G., Celermajer, D. (2009). Dietary supplementation with n-3 polyunsaturated fatty acids in early childhood: Effects on blood pressure and arterial structure and function at age 8 y1-3. American Journal of Clinical Nutrition, 90, 438-446. [More Information]
- Ayer, J., Harmer, J., Nakhla, S., Xuan, W., Ng, M., Raitakari, O., Marks, G., Celermajer, D. (2009). HDL-cholesterol, blood pressure, and asymmetric dimethylarginine are significantly associated with arterial wall thickness in children. Arteriosclerosis, Thrombosis, and Vascular Biology, 29(6), 943-949. [More Information]
- Ayer, J., Sullivan, D., Sholler, G. (2009). Lipid abnormalities in children: should we be doing more? Medical Journal of Australia, 190(3), 107-108. [More Information]
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2006
- Celermajer, D., Ayer, J. (2006). Childhood risk factors for adult cardiovascular disease and primary prevention in childhood. Heart, 92(11), 1701-1706. [More Information]
- Egan, J., Clarke, A., Williams, S., Cole, A., Ayer, J., Jacobe, S., Chard, R., Winlaw, D. (2006). Levosimendan for low cardiac output: a pediatric experience. Journal of Intensive Care Medicine, 21(3), 183-187. [More Information]
Selected Grants
2020
- Congenital Heart Fitness Intervention Trial: CH-FIT, Cordina R, Celermajer D, Ayer J, Tran D, Davis G, Department of Health and Aged Care (Federal)/MRFF - Accelerated Research - Congenital Heart Disease
2018
- Determining the associats and potential significance of diffuse myocardial fibrosisin patients with Duchenne Muscular Dystrophy and normal left ventricularfunction a pilot study, Ayer J, Sydney Childrens Hospitals Network/Externally Funded Position
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