Dr Kate Simms
Sydney School of Public Health
Faculty of Medicine and Health
Lead, Cervical Cancer and HPV Stream
The Daffodil Centre
Dr Kate Simms is a Senior Research Fellow at the Daffodil Centre. Dr Simms currently holds a Career Development Fellowship from Cancer Institute, and is currently also funded by CISNET-cervical, a US-NIH funded grant involving a consortium of modellers who use comparative modelling to assess the impact of cervical cancer prevention in USA. Dr Simms’research has had significant policy impact: in 2014 she co-led the economic evaluation to inform Australia’s cervical screening renewal, which directly informed the government’s decision to switch from 2-yearly cytology to 5-yearly primary HPV testing. Dr Simmsled the modelled evaluation on the potential for cervical cancer elimination for 181 countries, in collaboration with the International Agency for Research on Cancer, and was one of the researchers involved in the Cervical Cancer Elimination Modelling Consortium that directly informed WHO cervical cancer elimination strategy. Dr Simms is currently involved in modelling a range of cervical cancer screening guidelines to directly inform WHO’s updated cervical cancer screening guidelines. She has also been involved evaluations across a range of other countries, including modelling to inform the impact of vaccine hesitancy in Japan, and modelling to determine the optimal screening strategy for women in Urban China.
Dr Simms interests are in health economics and modelling of cervical cancer prevention strategies in low-and lower-middle income countries
- modelled evaluations to inform 2021 WHO cervical screening guidelines;
- modelled evaluations to inform evaluations for US-NIH funded CISNET grant;
- modelled evaluations to inform optimal screening in Guam and Yap.
Project title | Research student |
---|---|
Cervical screening in women with Down syndrome | Sally BYATT |
Evaluation of Effectiveness and Cost Effectiveness of HPV Vaccination Program in combination with Potential Cervical Cancer Screening and Treatment Strategies and Estimation of Timeframe towards Cervical Cancer Elimination in Myanmar | Tay Za Kyi Win WIN |
Publications
Journals
- Qin, J., Marfel, M., Simms, K., Canfell, K., Maxwell, K., Saraiya, M., Palafox, N., Scarinci, I., Lu, E., Senkomago, V., Nguyen, D., et al (2024). Building Capacity for Cervical Cancer Prevention in U.S.-Affiliated Pacific Islands: The Pacific Against Cervical Cancer Project. Journal of Women's Health. [More Information]
- Wee, H., Canfell, K., Chiu, H., Choi, K., Cox, B., Bhoo-Pathy, N., Simms, K., Hamashima, C., Shen, Q., Chua, B., et al (2024). Cancer screening programs in South-east Asia and Western Pacific. BMC Health Services Research, 24(1). [More Information]
- Nickson, C., Smith, M., Feletto, E., Velentzis, L., Broun, K., Deij, S., Grogan, P., Hall, M., He, E., St John, D., Lew, J., Procopio, P., Simms, K., Worthington, J., Canfell, K., et al (2023). A modelled evaluation of the impact of COVID-19 on breast, bowel, and cervical cancer screening programmes in Australia. eLife, 12. [More Information]
Magazine / Newspaper Articles
- Canfell, K., Hall, M., Simms, K., Smith, M., Saville, M. (2018). Australia on-track to be the first country to achieve cervical cancer elimination. HPV World.
Report
- Smith, M., Hall, M., Simms, K., Killen, J., Sherrah, M., O’Farrell, X., Canfell, K., Grogan, P. (2020). Modelled analysis of hypothetical impacts of COVID-19 related disruptions to the National Cervical Screening Program.
2024
- Qin, J., Marfel, M., Simms, K., Canfell, K., Maxwell, K., Saraiya, M., Palafox, N., Scarinci, I., Lu, E., Senkomago, V., Nguyen, D., et al (2024). Building Capacity for Cervical Cancer Prevention in U.S.-Affiliated Pacific Islands: The Pacific Against Cervical Cancer Project. Journal of Women's Health. [More Information]
- Wee, H., Canfell, K., Chiu, H., Choi, K., Cox, B., Bhoo-Pathy, N., Simms, K., Hamashima, C., Shen, Q., Chua, B., et al (2024). Cancer screening programs in South-east Asia and Western Pacific. BMC Health Services Research, 24(1). [More Information]
2023
- Nickson, C., Smith, M., Feletto, E., Velentzis, L., Broun, K., Deij, S., Grogan, P., Hall, M., He, E., St John, D., Lew, J., Procopio, P., Simms, K., Worthington, J., Canfell, K., et al (2023). A modelled evaluation of the impact of COVID-19 on breast, bowel, and cervical cancer screening programmes in Australia. eLife, 12. [More Information]
2022
- Vallely, A., Saville, M., Badman, S., Gabuzzi, J., Bolnga, J., Mola, G., Kuk, J., Wai, M., Munnull, G., Garland, S., Simms, K., Canfell, K., et al (2022). Point-of-care HPV DNA testing of self-collected specimens and same-day thermal ablation for the early detection and treatment of cervical pre-cancer in women in Papua New Guinea: a prospective, single-arm intervention trial (HPV-STAT). The Lancet Global Health, 10(9), e1336-e1346. [More Information]
- Kang, Y., Caruana, M., McLoughlin, K., Killen, J., Simms, K., Taylor, N., Frayling, I., Coupe, V., Boussioutas, A., Trainer, A., Ward, R., Canfell, K., et al (2022). The predicted effect and cost-effectiveness of tailoring colonoscopic surveillance according to mismatch repair gene in patients with Lynch syndrome. Genetics in Medicine, 24(9), 1831-1846. [More Information]
2021
- Smith, M., Hall, M., Saville, M., Brotherton, J., Simms, K., Lew, J., Bateson, D., Skinner, R., Kelaher, M., Canfell, K. (2021). Could HPV testing on self-collected samples be routinely used in an organized cervical screening program? A modeled analysis. Cancer Epidemiology Biomarkers and Prevention, 30(2), 268-277. [More Information]
- Hall, M., Smith, M., Simms, K., Barnabas, R., Murray, J., Canfell, K. (2021). Elimination of cervical cancer in Tanzania: Modelled analysis of elimination in the context of endemic HIV infection and active HIV control. International Journal of Cancer, 149(2), 297-306. [More Information]
- Keane, A., Shi, J., Simms, K., Liu, Y., Lew, J., Mazariego, C., Yuill, S., Wu, R., Liu, Z., Zhao, F., Canfell, K., et al (2021). Health economic evaluation of primary human papillomavirus screening in urban populations in China. Cancer Epidemiology, 70, 101861. [More Information]
2020
- Burger, E., de Kok, I., Groene, E., Killen, J., Canfell, K., Kulasingam, S., Kuntz, K., Matthijsse, S., Regan, C., Simms, K., Smith, M., et al (2020). Estimating the Natural History of Cervical Carcinogenesis Using Simulation Models: A CISNET Comparative Analysis. Journal of the National Cancer Institute, 14(10), 1-9. [More Information]
- Simms, K., Yuill, S., Killen, J., Smith, M., Kulasingam, S., de Kok, I., van Ballegooijen, M., Burger, E., Regan, C., Kim, J., Canfell, K. (2020). Historical and projected hysterectomy rates in the USA: Implications for future observed cervical cancer rates and evaluating prevention interventions. Gynecologic Oncology, 158(3), 710-718. [More Information]
- Brisson, M., Kim, J., Canfell, K., Drolet, M., Gingras, G., Burger, E., Martin, D., Simms, K., Bénard, É., Boily, M., Keane, A., Caruana, M., Nguyen, D., Smith, M., et al (2020). Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries. The Lancet, 395(10224), 575-590. [More Information]
2019
- Simms, K., Smith, M., Caruana, M., Canfell, K. (2019). An HBV booster shot at age 10 could be cost-saving: but is it too soon to tell? International Journal of Infectious Diseases, 78, 128-129. [More Information]
- Lew, J., Feletto, E., Wade, S., Caruana, M., Kang, Y., Nickson, C., Simms, K., Procopio, P., Taylor, N., Worthington, J., Smith, D., Canfell, K. (2019). Benefits, harms and cost-effectiveness of cancer screening in Australia: An overview of modelling estimates. Public Health Research and Practice, 29(2), 1-11. [More Information]
- Hall, M., Smith, M., Brotherton, J., Simms, K., Canfell, K. (2019). Cancer elimination thresholds: one size does not fit all - Authors' reply. The Lancet Public Health, 4(2), e87. [More Information]
2018
- Canfell, K., Hall, M., Simms, K., Smith, M., Saville, M. (2018). Australia on-track to be the first country to achieve cervical cancer elimination. HPV World.
- Hall, M., Simms, K., Lew, J., Smith, M., Saville, M., Canfell, K. (2018). Projected future impact of HPV vaccination and primary HPV screening on cervical cancer rates from 2017-2035: Example from Australia. PloS One, 13(2), 1-19. [More Information]
2017
- Velentzis, L., Caruana, M., Simms, K., Lew, J., Shi, J., Saville, M., Smith, M., Lord, S., Tan, J., Bateson, D., Canfell, K., et al (2017). How will transitioning from cytology to HPV testing change the balance between the benefits and harms of cervical cancer screening? Estimates of the impact on cervical cancer, treatment rates and adverse obstetric outcomes in Australia, a high vaccination coverage country. International Journal of Cancer, 141(12), 2410-2422. [More Information]
- Simms, K., Hall, M., Smith, M., Lew, J., Hughes, S., Yuill, S., Hammond, I., Saville, A., Canfell, K. (2017). Optimal management strategies for primary HPV testing for cervical screening: Cost-effectiveness evaluation for the national cervical screening program in Australia. PloS One, 12(1), 1-23. [More Information]
- Lew, J., Simms, K., Smith, M., Hall, M., Kang, Y., Xu, X., Caruana, M., Velentzis, L., Bessell, T., Saville, A., Canfell, K., et al (2017). Primary HPV testing versus cytology-based cervical screening in women in Australia vaccinated for HPV and unvaccinated: effectiveness and economic assessment for the National Cervical Screening Program. The Lancet Public Health, 2(2), e96-e107. [More Information]
2016
- Simms, K., Laprise, J., Smith, M., Lew, J., Caruana, M., Brisson, M., Canfell, K. (2016). Cost-effectiveness of the next generation nonavalent human papillomavirus vaccine in the context of primary human papillomavirus screening in Australia: a comparative modelling analysis. The Lancet Public Health, 1(2), e66-e75. [More Information]
- Lew, J., Simms, K., Smith, M., Lewis, H., Neal, H., Canfell, K. (2016). Effectiveness modelling and economic evaluation of primary HPV screening for cervical cancer prevention in New Zealand. PloS One, 11(5), 1-21. [More Information]
- Smith, M., Lew, J., Simms, K., Canfell, K. (2016). Impact of HPV sample self-collection for underscreened women in the renewed Cervical Screening Program. Medical Journal of Australia, 204(5), 194.e1-194.e9. [More Information]
Selected Grants
2020
- Evaluating Novel Interventions To Facilitate Cervical Cancer Elimination Across Low and-Middle Income Countries And High Income Countries: A Modelled Evaluation, Simms K, Cancer Institute NSW/Career Development Fellowship
2017
- Centre for Research Excellence in Cervical Cancer Control (C4), Canfell K, Brotherton J, Saville M, Castle P, Kaldor J, Garland S, Kelaher M, Guy R, Vallely A, Simms K, National Health and Medical Research Council (NHMRC)/Centres of Research Excellence