2024

• Cunningham, A., Micklethwaite, K. (2024). A new way of identifying viral pathogens reactivating in cellular therapy products. Immunology and Cell Biology. [More Information]
• Klapwijk, J., Zeller, A., Biasco, L., Brugman, M., Bushmann, F., Cathomen, T., Ertl, H., Gabriel, R., Gao, G., Jadlowsky, J., Micklethwaite, K., et al (2024). Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article. Human Gene Therapy, 35(15-16), 527-542. [More Information]

2023

• Louie, R., Cai, C., Samir, J., Singh, M., Deveson, I., Ferguson, J., Amos, T., McGuire, H., Gowrishankar, K., Adikari, T., Bishop, D., Gottlieb, D., Blyth, E., Micklethwaite, K., et al (2023). CAR+ and CAR− T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies. Nature Communications, 14(1). [More Information]
• Bak, G., Micklethwaite, K., Maddock, K., Coggins, A. (2023). Chimeric antigen receptor T-cell therapy: Prospective observational study of unplanned emergency department presentations. EMA - Emergency Medicine Australasia. [More Information]
• Gottlieb, D., Sutrave, G., Jiang, W., Avdic, S., Street, J., Simms, R., Clancy, L., Antonenas, V., Gloss, B., Bateman, C., Bishop, D., Micklethwaite, K., Blyth, E. (2023). Combining CD34+ stem cell selection with prophylactic pathogen and leukemia directed T-cell immunotherapy to simultaneously reduce graft versus host disease, infection, and leukemia recurrence after allogeneic stem cell transplant. American Journal Of Hematology, 98(1), 159-165. [More Information]
• Chen, Y., Mach, M., Shokouhi, A., Yoh, H., Bishop, D., Murayama, T., Suu, K., Morikawa, Y., Barry, S., Micklethwaite, K., et al (2023). Efficient non-viral CAR-T cell generation via silicon-nanotube-mediated transfection. Materials Today, 63. [More Information]
• Blennerhassett, R., Othman, J., Biscoe, A., Kliman, D., Mills, G., Blyth, E., Micklethwaite, K., Kwan, J., Bilmon, I., Bhattacharyya, A., Stevenson, W., Greenwood, M., Gottlieb, D., Kerridge, I., et al (2023). Long-term outcomes of corticosteroid graft versus host disease prophylaxis in peripheral blood allogeneic haemopoietic stem cell transplant: a comparative cohort analysis. Internal Medicine Journal. [More Information]
• Jiang, W., Avdic, S., Lee, K., Street, J., Castellano-Gonzalez, G., Simms, R., Clancy, L., Blennerhassett, R., Patrick, E., Chan, A., McGuire, H., Myers, N., Gloss, B., Bateman, C., Micklethwaite, K., Gottlieb, D., Blyth, E., et al (2023). Persistence of ex vivo expanded tumour and pathogen specific T-cells after allogeneic stem cell transplant for myeloid malignancies (the INTACT study). Leukemia, 37(11), 2330-2333. [More Information]

2022

• Sutrave, G., Xu, N., Tang, T., Dolnikov, A., Gloss, B., Gottlieb, D., Micklethwaite, K., Gowrishankar, K. (2022). Characterizing piggyBat-a transposase for genetic modification of T cells. Molecular Therapy - Methods & Clinical Development, 25, 250-263. [More Information]
• Tang, T., Xu, N., Nordon, R., Haber, M., Micklethwaite, K., Dolnikov, A. (2022). Donor T cells for CAR T cell therapy. Biomarker Research, 10(1), 14. [More Information]
• York, J., Gowrishankar, K., Micklethwaite, K., Palmer, S., Cunningham, A., Nasr, N. (2022). Evolving Strategies to Eliminate the CD4 T Cells HIV Viral Reservoir via CAR T Cell Immunotherapy. Frontiers in Immunology, 13, 873701. [More Information]
• Jiang, W., Clancy, L., Avdic, S., Sutrave, G., Street, J., Simms, R., McGuire, H., Patrick, E., Chan, A., McCaughan, G., Myers, N., Micklethwaite, K., Bateman, C., Shaw, P., Blyth, E., Gottlieb, D., et al (2022). Third-party CMV- and EBV-specific T-cells for first viral reactivation after allogeneic stem cell transplant. Blood Advances, 6(17), 4949-4966. [More Information]

2021

• Gottlieb, D., Blyth, E., Micklethwaite, K., Clancy, L., Deo, S. (2021). Production of a T cell product targeting viral and fungal infections for the prevention and treatment of opportunistic infection in immunocompromised individuals. Patent No. 10940165.
• Bishop, D., Clancy, L., Simms, R., Burgess, J., Mathew, G., Moezzi, L., Street, J., Sutrave, G., Atkins, E., McGuire, H., Lee, K., Jiang, W., McCaughan, G., Shaw, P., Gottlieb, D., Blyth, E., Micklethwaite, K., et al (2021). Development of CAR T-cell lymphoma in 2 of 10 patients effectively treated with piggyBac-modified CD19 CAR T cells. Blood, 138(16), 1504-1509. [More Information]
• Purtill, D., Hutchins, C., Kennedy, G., McClean, A., Fraser, C., Shaw, P., Chiappini, P., Tao, H., Ma, D., Kabani, K., Greenwood, M., Gottlieb, D., et al (2021). Good Engraftment but Quality and Donor Concerns for Cryopreserved Hemopoietic Progenitor Cell Products Collected During the COVID-19 Pandemic. Transplantation and Cellular Therapy, 27(12), 1022.e1-1022.e6. [More Information]
• Micklethwaite, K., Gowrishankar, K., Gloss, B., Li, Z., Street, J., Moezzi, L., Mach, M., Sutrave, G., Clancy, L., Bishop, D., Gottlieb, D., Blyth, E., et al (2021). Investigation of product-derived lymphoma following infusion of piggyBac-modified CD19 chimeric antigen receptor T cells. Blood, 138(16), 1391-1405. [More Information]
• Habib, R., Burgess, N., Bourke, M., Wong, M., Wilcken, N., Toh, J., El-Khoury, T., Pathma-Nathan, N., Ctercteko, G., Jayamohan, J., Micklethwaite, K., Nagrial, A. (2021). Outcomes of young patients diagnosed with locally advanced rectal cancer. Journal of Gastrointestinal Oncology, 12(2), 592-601. [More Information]
• Xu, N., Tse, B., Yang, L., Tang, T., Haber, M., Micklethwaite, K., Dolnikov, A. (2021). Priming Leukemia with 5-Azacytidine Enhances CAR T Cell Therapy. ImmunoTargets and Therapy, 10, 123-140. [More Information]
• Gottlieb, D., Clancy, L., Withers, B., McGuire, H., Luciani, F., Singh, M., Hughes, B., Gloss, B., Kliman, D., Ma, C., Bishop, D., Dubosq, M., Li, Z., Avdic, S., Micklethwaite, K., Blyth, E., et al (2021). Prophylactic antigen-specific T-cells targeting seven viral and fungal pathogens after allogeneic haemopoietic stem cell transplant. Clinical & Translational Immunology, 10(3), e1249. [More Information]

2020

• Bishop, D., Caproni, L., Gowrishankar, K., Legiewicz, M., Karbowniczek, K., Tite, J., Gottlieb, D., Micklethwaite, K. (2020). CAR T Cell Generation by piggyBac Transposition from Linear Doggybone DNA Vectors Requires Transposon DNA-Flanking Regions. Molecular Therapy - Methods & Clinical Development, 17, 359-368. [More Information]
• Habib, R., Nagrial, A., Micklethwaite, K., Gowrishankar, K. (2020). Chimeric Antigen Receptors for the Tumour Microenvironment. Advances in Experimental Medicine and Biology, 1263, 117-143. [More Information]
• Lee, K., Gowrishankar, K., Street, J., McGuire, H., Luciani, F., Hughes, B., Singh, M., Clancy, L., Gottlieb, D., Micklethwaite, K., Blyth, E. (2020). Ex vivo enrichment of PRAME antigen-specific T cells for adoptive immunotherapy using CD137 activation marker selection. Clinical & Translational Immunology, 9(e1200), 1-13. [More Information]
• Getta, B., Tong, D., Deren, S., Huang, G., Hogg, M., Collins, D., Bhattacharyya, A., Panicker, S., Micklethwaite, K., Blyth, E., Bilmon, I., Gottlieb, D., et al (2020). Pre- and post-bone marrow harvest anaemia is associated with lower CD34+ stem cell collection, high harvest volume and female gender. Internal Medicine Journal, 50(3), 299-306. [More Information]
• Othman, J., Greenwood, M., Moore, J., Larsen, S., Watson, A., Arthur, C., Bhattacharyya, A., Bilmon, I., Blyth, E., Bryant, A., Gibson, J., Kerridge, I., Stevenson, W., Gottlieb, D., et al (2020). Unrelated Donor Transplant Recipients Given Thymoglobuline Have Superior GRFS When Compared to Matched Related Donor Recipients Undergoing Transplantation without ATG. Biology of Blood and Marrow Transplantation, 26(10), 1868-1875. [More Information]

2019

• Lindsay, J., Teh, B., Micklethwaite, K., Slavin, M. (2019). Azole antifungals and new targeted therapies for hematological malignancy. Current Opinion in Infectious Diseases, 32(6), 538-545. [More Information]

2018

• Ma, C., Clancy, L., Simms, R., Burgess, J., Deo, S., Blyth, E., Micklethwaite, K., Gottlieb, D. (2018). Adjuvant Peptide Pulsed Dendritic Cell Vaccination in Addition to T Cell Adoptive Immunotherapy for Cytomegalovirus Infection in Allogeneic Hematopoietic Stem Cell Transplantation Recipients. Biology of Blood and Marrow Transplantation, 24(1), 71-77. [More Information]
• Withers, B., Clancy, L., Burgess, J., Simms, R., Brown, R., Micklethwaite, K., Blyth, E., Gottlieb, D. (2018). Establishment and Operation of a Third-Party Virus-Specific T Cell Bank within an Allogeneic Stem Cell Transplant Program. Biology of Blood and Marrow Transplantation, 24(12), 2433-2442. [More Information]
• Gowrishankar, K., Birtwistle, L., Micklethwaite, K. (2018). Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells. Mammalian Genome, 29(11-12), 739-756. [More Information]
• Bishop, D., Xu, N., Tse, B., O'Brien, T., Gottlieb, D., Dolnikov, A., Micklethwaite, K. (2018). PiggyBac-Engineered T Cells Expressing CD19-Specific CARs that Lack IgG1 Fc Spacers Have Potent Activity against B-ALL Xenografts. Molecular Therapy, 26(8), 1883-1895. [More Information]
• Kliman, D., Bilmon, I., Kwan, J., Blyth, E., Micklethwaite, K., Panicker, S., Bhattacharyya, A., Deren, S., Antonenas, V., Huang, G., Gottlieb, D. (2018). Rescue haploidentical peripheral blood stem cell transplantation for engraftment failure: a single-centre case series. Internal Medicine Journal, 48(8), 988-991. [More Information]

2017

• Ma, C., Clancy, L., Deo, S., Blyth, E., Micklethwaite, K., Gottlieb, D. (2017). Herpes simplex virus type 1 (HSV-1) specific T-cell generation from HLA-A1- and HLA-A2-positive donors for adoptive immunotherapy. Cytotherapy, 19(1), 107-118. [More Information]
• Withers, B., Blyth, E., Clancy, L., Yong, A., Fraser, C., Burgess, J., Simms, R., Brown, R., Kliman, D., Dubosq, M., Bishop, D., Sutrave, G., Ma, C., Micklethwaite, K., Gottlieb, D., et al (2017). Long-term control of recurrent or refractory viral infections after allogeneic HSCT with third-party virus-specific T cells. Blood Advances, 1(24), 2193-2205. [More Information]

2016

• Kong, B., Micklethwaite, K., Swaminathan, S., Kefford, R., Carlino, M. (2016). Autoimmune hemolytic anemia induced by anti-PD-1 therapy in metastatic melanoma. Melanoma Research, 26(2), 202-204. [More Information]

2015

• Ma, C., Blyth, E., Clancy, L., Simms, R., Burgess, J., Brown, R., Deo, S., Micklethwaite, K., Gottlieb, D. (2015). Addition of varicella zoster virus-specific T cells to cytomegalovirus, Epstein-Barr virus and adenovirus tri-specific T cells as adoptive immunotherapy in patients undergoing allogeneic hematopoietic stem cell transplantation. Cytotherapy, 17(10), 1406-1420. [More Information]
• Macesic, N., Langsford, D., Nicholls, K., Hughes, P., Gottlieb, D., Clancy, L., Blyth, E., Micklethwaite, K., Withers, B., Majumdar, S., et al (2015). Adoptive T cell immunotherapy for treatment of ganciclovir-resistant cytomegalovirus disease in a renal transplant recipient. American Journal Of Transplantation, 15(3), 827-832. [More Information]
• Dolnikov, A., Shen, S., Klamer, G., Joshi, S., Xu, N., Yang, L., Micklethwaite, K., O'Brien, T. (2015). Anti-leukemic potency of CD19-specific T cells against chemoresistant paediatric acute lymphoblastic leukaemia. Experimental Hematology, 43(12), 1001-1014. [More Information]
• Ramanayake, S., Bilmon, I., Bishop, D., Dubosq, M., Blyth, E., Clancy, L., Gottlieb, D., Micklethwaite, K. (2015). Low-cost generation of Good Manufacturing Practice-grade CD19-specific chimeric antigen receptor-expressing T cells using piggyBac gene transfer and patient-derived materials. Cytotherapy, 17(9), 1251-1267. [More Information]
• Bradstock, K., Bilmon, I., Kwan, J., Micklethwaite, K., Blyth, E., Deren, S., Bayley, A., Gebski, V., Gottlieb, D. (2015). Single-agent high-dose cyclophosphamide for graft-versus-host disease prophylaxis in human leukocyte antigen-matched reduced-intensity peripheral blood stem cell transplantation results in an unacceptably high rate of severe acute graft-versus-host disease. Biology of Blood and Marrow Transplantation, 21(5), 941-944. [More Information]

2013

• Clancy, L., Blyth, E., Simms, R., Micklethwaite, K., Ma, C., Burgess, J., Antonenas, V., Shaw, P., Gottlieb, D. (2013). Cytomegalovirus-specific cytotoxic T lymphocytes can be efficiently expanded from granulocyte colony-stimulating factor-mobilized hemopoietic progenitor cell products ex vivo and safely transferred to stem cell transplantation recipients to facilitate immune reconstitution. Biology of Blood and Marrow Transplantation, 19(5), 725-734. [More Information]
• Blyth, E., Clancy, L., Simms, R., Ma, C., Burgess, J., Deo, S., Byth Wilson, K., Dubosq, M., Shaw, P., Micklethwaite, K., Gottlieb, D. (2013). Donor-derived CMV specific T-cells reduce the requirement for CMV-directed pharmacotherapy after allogeneic stem cell transplantation. Blood, 121(18), 3745-3758. [More Information]
• Cruz, C., Micklethwaite, K., Savoldo, B., Ramos, C., Lam, S., Ku, S., Diouf, O., Liu, E., Barrett, A., Ito, S., et al (2013). Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study. Blood, 122(17), 2965-2973. [More Information]

2012

• Blyth, E., Deo, S., Clancy, L., Simms, R., Bilmon, I., Micklethwaite, K., Gottlieb, D. (2012). Clinical-grade varicella zoster virus-specific T cells produced for adoptive immunotherapy in hemopoietic stem cell transplant recipients. Cytotherapy, 14(6), 724-732. [More Information]

2011

• Blyth, E., Clancy, L., Simms, R., Deo, S., O'Connell, P., Micklethwaite, K., Gottlieb, D. (2011). BK Virus-Specific T Cells for Use in Cellular Therapy Show Specificity to Multiple Antigens and Polyfunctional Cytokine Responses. Transplantation, 92(10), 1077-1084. [More Information]
• Gaundar, S., Clancy, L., Blyth, E., Simms, R., Micklethwaite, K., Gottlieb, D. (2011). The Generation of Clinical Grade Aspergillus Fumigatus (AF) Specific Immune Cells for Adoptive Immunotherapy. Biology of Blood and Marrow Transplantation, 17(2), S215-S215. [More Information]

2010

• Micklethwaite, K., Savoldo, B., Hanley, P., Leen, A., Demmler-Harrison, G., Cooper, L., Liu, H., Gee, A., Shpall, E., Rooney, C., et al (2010). Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation. Blood, 115(13), 2695-2703. [More Information]

2009

• Micklethwaite, K., Garvin, F., Kariotis, M., Yee, L., Hansen, A., Antonenas, V., Sartor, M., Turtle, C., Gottlieb, D. (2009). Clinical-scale elutriation as a means of enriching antigen-presenting cells and manipulating alloreactivity. Cytotherapy, 11(2), 218-228. [More Information]

2008

• Blyth, E., Micklethwaite, K., Clancy, L., Sandher, U., Gottlieb, D. (2008). Prophylactic Infusion of CMV Specific Cytotoxic T-Lymphocytes Following Allogeneic Haemopoietic Stem Cell Transplantation: 459. Transplantation, 86(2S), 161-162. [More Information]
• Micklethwaite, K., Clancy, L., Sandher, U., Hansen, A., Blyth, E., Antonenas, V., Sartor, M., Bradstock, K., Gottlieb, D. (2008). Prophylactic infusion of cytomegalovirus specific cytotoxic T-lymphocytes stimulated with Ad5f35pp65 gene modified dendritic cells following allogeneic haemopoietic stem cell transplantation. Blood, 112(10), 3974-3981. [More Information]

2007

• Micklethwaite, K., Hansen, A., Foster, A., Snape, E., Antonenas, V., Sartor, M., Shaw, P., Bradstock, K., Gottlieb, D. (2007). Ex vivo expansion and prophylactic infusion of CMV-pp65 peptide-specific cytotoxic T-lymphocytes following allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation, 13(6), 707-714. [More Information]
• Gottlieb, D., Micklethwaite, K., Bradstock, K., Li, Y. (2007). Rapid expansion of tumor-reactive cells from HLA-matched siblings for adoptive immunotherapy of melanoma. Cytotherapy, 9(2), 133-143. [More Information]

2006

• Hansen, A., Micklethwaite, K., Foster, A., Bradstock, K., Gottlieb, D. (2006). Ex vivo expansion of clinical grade CMV specific CTL for therapeutic use in allogeneic haemopoietic stem cell transplantation. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.

2005

• Gottlieb, D., Hansen, A., Micklethwaite, K., Foster, A., Turtle, C., Antonenas, V., Sartor, M., Bradstock, K. (2005). Ex-vivo expansion and prophylactic infusion of CMV pp65 specific CTL following haemopoietic stem cell transplantation (HSCT). 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.