Dr Kylie Shaddock
People_

Dr Kylie Shaddock

Lecturer
School of Medical Sciences
Faculty of Medicine and Health

Dr Shaddock (nee Webster) is an academic within the Discipline of Infectious Diseases and Immunology and the Education Innovation Theme of the School of Medical Sciences within the Faculty of Medicine and Health. She obtained a BSc (with Honours) from UNSW Sydney and a PhD in genetics and immunology from the University of Melbourne in 2005 for research conducted at the Walter & Eliza Hall Institute of Medical Research.

She then continued her research in immunological tolerance and autoimmunity at the Garvan Institute in Sydney, first as a postdoctoral researcher and later as a Group Leader and Conjoint Senior Lecturer with UNSW Sydney. In 2019 she took a position as a Research Project Manager to coordinate a clinical study on autoimmune disease at Liverpool Hospital. In 2020 Dr Shaddock was appointed as a teaching academic at the University of Sydney where she now coordinates the postgraduate units ‘Clinical Immunology and Immunotherapy and 'Infection and Immunity Capstone', along with the undergraduate unit 'Molecular and Cellullar Immunology'.

Dr Shaddock is a lecturer and unit coordinator of the postgraduate units ‘Clinical Immunology and Immunotherapy’ and 'Infection and Immunity Capstone', along with the undergraduate unit 'Molecular and Cellular Immunology'.

Infection and Immunological Conditions

Publications

Journals

  • Pilat, N., Wiletel, M., Weijler, A., Steiner, R., Mahr, B., Warren, J., Corpuz, T., Wekerle, T., Webster, K., Sprent, J. (2019). Treg-mediated prolonged survival of skin allografts without immunosuppression. Proceedings of the National Academy of Sciences of the United States of America, 116(27), 13508-13516. [More Information]
  • Corpuz, T., Vazquez-Lombardi, R., Luong, J., Warren, J., Stolp, J., Christ, D., King, C., Brink, R., Sprent, J., Webster, K. (2017). IL-2 shapes the survival and plasticity of IL-17-producing γδ T Cells. Journal of Immunology, 199(7), 2366-2376. [More Information]
  • Jandl, C., Liu, S., Canete, P., Warren, J., Hughes, W., Vogelzang, A., Webster, K., Craig, M., Uzel, G., Dent, A., et al (2017). IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2. Nature Communications, 8, 1-14. [More Information]

2019

  • Pilat, N., Wiletel, M., Weijler, A., Steiner, R., Mahr, B., Warren, J., Corpuz, T., Wekerle, T., Webster, K., Sprent, J. (2019). Treg-mediated prolonged survival of skin allografts without immunosuppression. Proceedings of the National Academy of Sciences of the United States of America, 116(27), 13508-13516. [More Information]

2017

  • Corpuz, T., Vazquez-Lombardi, R., Luong, J., Warren, J., Stolp, J., Christ, D., King, C., Brink, R., Sprent, J., Webster, K. (2017). IL-2 shapes the survival and plasticity of IL-17-producing γδ T Cells. Journal of Immunology, 199(7), 2366-2376. [More Information]
  • Jandl, C., Liu, S., Canete, P., Warren, J., Hughes, W., Vogelzang, A., Webster, K., Craig, M., Uzel, G., Dent, A., et al (2017). IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2. Nature Communications, 8, 1-14. [More Information]
  • Vazquez-Lombardi, R., Loetsch, C., Zinkl, D., Jackson, J., Schofield, P., Deenick, E., King, C., Phan, T., Webster, K., Sprent, J., et al (2017). Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells. Nature Communications, 8, 15373. [More Information]

2016

  • Cho, J., Kim, H., Ju, Y., Kye, Y., Lee, G., Lee, S., Yun, C., Bottini, N., Webster, K., Goodnow, C., et al (2016). CD45-mediated control of TCR tuning in naive and memory CD8+ T cells. Nature Communications, 7, 13373-1-13373-15. [More Information]
  • Pinget, G., Corpuz, T., Stolp, J., Lousberg, E., Diener, K., Robertson, S., Sprent, J., Webster, K. (2016). The majority of murine (gamma)(delta) T cells at the maternal-fetal interface in pregnancy produce IL-17. Immunology and Cell Biology, 94(7), 623-630. [More Information]

2012

  • Polhill, T., Zhang, G., Hu, M., Sawyer, A., Zhou, J., Saito, M., Webster, K., Wang, Y., Wang, Y., Grey, S., Harris, D., Alexander, S., Wang, Y., et al (2012). IL-2/IL-2Ab Complexes Induce Regulatory T Cell Expansion and Protect against Proteinuric CKD. Journal of the American Society of Nephrology, 23(8), 1303-1308. [More Information]

2011

  • Cho, J., Kim, H., Webster, K., Palendira, M., Hahm, B., Kim, K., King, C., Tangye, S., Sprent, J. (2011). Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cells. Blood, 118(1), 116-128. [More Information]
  • McGuire, H., Walters, S., Vogelzang, A., Lee, C., Webster, K., Sprent, J., Christ, D., Grey, S., King, C. (2011). Interleukin-21 Is Critically Required in Autoimmune and Allogeneic Responses to Islet Tissue in Murine Models. Diabetes, 60(3), 867-875. [More Information]