People_

Dr Lara Elizabeth Graves

BVSc(HonsI) MBBS(HonsI) DCH PhD FRACP

Conjoint Lecturer
Sydney Medical School
Children's Hospital at Westmead
Faculty of Medicine and Health

Email

lara.graves@sydney.edu.au

Websites

ORCid

Biographical details

Lara Graves is a paediatric endocrinologist at The Children’s Hospital at Westmead, with clinical and research interests in monogenic endocrine disorders.

Research interests

Lara Graves has a research interest in advanced therapeutics for endocrinology and is currently developing a pre-clinical AAV-based approach for the treatment of congenital adrenal hyperplasia.

Awards and honours

Adrenals and HPA Axis: Best Oral Award, 11^th International Meeting of Pediatric Endocrinology 2023, Buenos Aires, Argentina. “Comparing the single cell transcriptome of wild-type and 21-hydroxylase deficient murine adrenal glands”

Emerging Investigator of the Year Prize, APEG Annual Scientific Meeting 2021, Virtual Conference. “Inducing ectopic 21-hydroxylase expression in a mouse model for congenital adrenal hyperplasia through hepatocyte-targeting gene addition”

Themes

Obesity, Diabetes and Cardiovascular Disease, Reproductive, Maternal and Child Health

Keywords

Endocrinology, Genetic diseases, Paediatrics and Child Health, Animal Models

Clinical speciality

Endocrinology

Publications

By Type

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Journals

Graves, L., van Dijk, E., Zhu, E., Koyyalamudi, S., Wotton, T., Sung, D., Srinivasan, S., Ginn, S., Alexander, I. (2024). AAV-delivered hepato-adrenal cooperativity in steroidogenesis: Implications for gene therapy for congenital adrenal hyperplasia. Molecular Therapy - Methods & Clinical Development, 32(2), 101232. [More Information]
Graves, L., Torpy, D., Coates, P., Alexander, I., Bornstein, S., Clarke, B. (2023). Future Directions for Adrenal Insufficiency: Cellular Transplantation and Genetic Therapies. Journal of Clinical Endocrinology and Metabolism, 108(6), 1273-1289. [More Information]
Graves, L., Horton, A., Alexander, I., Srinivasan, S. (2023). Gene Therapy for Paediatric Homozygous Familial Hypercholesterolaemia. Heart, Lung, and Circulation. [More Information]
McGee, R., Graves, L., Barnett, A. (2022). Timing of submissions to the Journal of Paediatrics and Child Health: associations with the Covid-19 pandemic and editorial decisions. Journal of Paediatrics and Child Health, 59(1), 89-94. [More Information]
Graves, L., Stewart, K., Ambler, G., Bhattacharya, K., Srinivasan, S. (2021). Investigating paediatric hypoglycaemia: Dynamic studies at a tertiary paediatric hospital. Journal of Paediatrics and Child Health, 57(6), 888-893. [More Information]
Graves, L., Khouri, J., Kristidis, P., Verge, C. (2021). Proopiomelanocortin deficiency diagnosed in infancy in two boys and a review of the known cases. Journal of Paediatrics and Child Health, 57(4), 484-490. [More Information]
Graves, L., Pryke, A., Cho, Y., Cusumano, J., Craig, M., Liew, G., Donaghue, K. (2021). Sight-threatening retinopathy in nine adolescents with early onset type 1 diabetes. Pediatric Diabetes, 22(8), 1129-1134. [More Information]
Graves, L., Wall, C., Briody, J., Bennetts, B., Wong, K., Onikul, E., Biggin, A., Munns, C. (2020). High Bone Mineral Density Osteogenesis Imperfecta in a Family with a Novel Pathogenic Variant in COL1A2. Hormone Research in Paediatrics, 93(4), 263-271. [More Information]
Graves, L., Donaghue, K. (2020). Vascular Complication in Adolescents With Diabetes Mellitus. Frontiers in Endocrinology, 11(9), 370-1-370-10. [More Information]
Graves, L., Donaghue, K. (2019). Management of diabetes complications in youth. Therapeutic Advances in Endocrinology and Metabolism, 10, 1-12. [More Information]
Graves, L., Chayen, G., Peat, J., O'Leary, F. (2014). A comparison of actual to estimated weights in Australian children attending a tertiary children's' hospital, using the original and updated APLS, Luscombe and Owens, Best Guess formulae and the Broselow tape. Resuscitation, 85(3), 392-396. [More Information]
Graves, L., Garnett, S., Cowell, C., Baur, L., Ness, A., Sattar, N., Lawlor, D. (2014). Waist-to-height ratio and cardiometabolic risk factors in adolescence: findings from a prospective birth cohort. Pediatric Obesity, 9(5), 327-338. [More Information]
Graves, L., Hennessy, A., Sunderland, N., Heffernan, S., Thomson, S. (2009). Incidence of lymphoma in a captive-bred colony of hamadryas baboons (Papio hamadryas). Australian Veterinary Journal, 87(6), 238-243. [More Information]

show 10 more

By Year

Expand all

2024

Graves, L., van Dijk, E., Zhu, E., Koyyalamudi, S., Wotton, T., Sung, D., Srinivasan, S., Ginn, S., Alexander, I. (2024). AAV-delivered hepato-adrenal cooperativity in steroidogenesis: Implications for gene therapy for congenital adrenal hyperplasia. Molecular Therapy - Methods & Clinical Development, 32(2), 101232. [More Information]

2023

Graves, L., Torpy, D., Coates, P., Alexander, I., Bornstein, S., Clarke, B. (2023). Future Directions for Adrenal Insufficiency: Cellular Transplantation and Genetic Therapies. Journal of Clinical Endocrinology and Metabolism, 108(6), 1273-1289. [More Information]
Graves, L., Horton, A., Alexander, I., Srinivasan, S. (2023). Gene Therapy for Paediatric Homozygous Familial Hypercholesterolaemia. Heart, Lung, and Circulation. [More Information]

2022

McGee, R., Graves, L., Barnett, A. (2022). Timing of submissions to the Journal of Paediatrics and Child Health: associations with the Covid-19 pandemic and editorial decisions. Journal of Paediatrics and Child Health, 59(1), 89-94. [More Information]

2021

Graves, L., Stewart, K., Ambler, G., Bhattacharya, K., Srinivasan, S. (2021). Investigating paediatric hypoglycaemia: Dynamic studies at a tertiary paediatric hospital. Journal of Paediatrics and Child Health, 57(6), 888-893. [More Information]
Graves, L., Khouri, J., Kristidis, P., Verge, C. (2021). Proopiomelanocortin deficiency diagnosed in infancy in two boys and a review of the known cases. Journal of Paediatrics and Child Health, 57(4), 484-490. [More Information]
Graves, L., Pryke, A., Cho, Y., Cusumano, J., Craig, M., Liew, G., Donaghue, K. (2021). Sight-threatening retinopathy in nine adolescents with early onset type 1 diabetes. Pediatric Diabetes, 22(8), 1129-1134. [More Information]

2020

Graves, L., Wall, C., Briody, J., Bennetts, B., Wong, K., Onikul, E., Biggin, A., Munns, C. (2020). High Bone Mineral Density Osteogenesis Imperfecta in a Family with a Novel Pathogenic Variant in COL1A2. Hormone Research in Paediatrics, 93(4), 263-271. [More Information]
Graves, L., Donaghue, K. (2020). Vascular Complication in Adolescents With Diabetes Mellitus. Frontiers in Endocrinology, 11(9), 370-1-370-10. [More Information]

2019

Graves, L., Donaghue, K. (2019). Management of diabetes complications in youth. Therapeutic Advances in Endocrinology and Metabolism, 10, 1-12. [More Information]

2014

Graves, L., Chayen, G., Peat, J., O'Leary, F. (2014). A comparison of actual to estimated weights in Australian children attending a tertiary children's' hospital, using the original and updated APLS, Luscombe and Owens, Best Guess formulae and the Broselow tape. Resuscitation, 85(3), 392-396. [More Information]
Graves, L., Garnett, S., Cowell, C., Baur, L., Ness, A., Sattar, N., Lawlor, D. (2014). Waist-to-height ratio and cardiometabolic risk factors in adolescence: findings from a prospective birth cohort. Pediatric Obesity, 9(5), 327-338. [More Information]

2009

Graves, L., Hennessy, A., Sunderland, N., Heffernan, S., Thomson, S. (2009). Incidence of lymphoma in a captive-bred colony of hamadryas baboons (Papio hamadryas). Australian Veterinary Journal, 87(6), 238-243. [More Information]

Selected Grants

2022