Professor Luis Vitetta
Sydney School of Pharmacy
Faculty of Medicine and Health
Clinical epidemiology / The human microbiome / Probiotics and Prebiotics and Mood Disorders / Cellular redox potential and pro-oxidant signaling systems
Epidemiology - Clinical Trials / Clinical Problem Based Learning / Microbiology / Nutritional Biochemistry / Physiology /
RHD COMPLETED: Talia PALACIOS CAMPANA
Research Project Title: The Effect of a Multi-strain Probiotic on Metabolic Biomarkers in Pre-diabetic Adults
The intestinal microbiome and chronic kidney disease.
Cannabis for intractable pain and chemotherapy induced nausea and vomiting.
Editorial Board Memberships
World Journal of Gastrointestinal Pharmacology and Therapeutics [2017 - 2020]
Journal of World Mitochondria Society [2015 - onging]
Inflammopharmacology [2014 - ongoing]
Journal of Controversies in Biomedical Research [2014 - 2019]
Advances in Integrative Medicine [2013 - 2018]
BMC Complementary and Alternative Medicine [2013 - ongoing]
Journal of Complementary Medicine [2008 - 2012]
Jourmnal of Functional Foods [2020 - ongoing]
Scientific Advisory Boards
Journal of Molecular Pathophysiology
Project title | Research student |
---|---|
Effects of Extra Virgin Olive Oil on Ulcerative Colitis | Kenneth DANIEL |
Pulmonary delivery of probiotic formulations in respiratory infections | Grace YAU |
Publications
Book Chapters
- Vitetta, L., Palacios, T., Hall, S., Coulson, S. (2015). Gastrointestinal Tract Commensal Bacteria and Probiotics: Influence on End-Organ Physiology. In K D Rainsford, M C Powanda, M W Whitehouse (Eds.), Novel Natural Products:Therapeutic Effects in Pain, Arthritis and Gastro-intestinal Diseases, (pp. 1-33). Basel: Springer. [More Information]
- Coulson, S., Palacios, T., Vitetta, L. (2015). Perna canaliculus (Green-Lipped Mussel): Bioactive Components and Therapeutic Evaluation for Chronic Health Conditions. In K D Rainsford, M C Powanda, M W Whitehouse (Eds.), Novel Natural Products:Therapeutic Effects in Pain, Arthritis and Gastro-intestinal Diseases, (pp. 91-132). Basel: Springer. [More Information]
Journals
- Thomsen, M., Vemuri, R., Huygens, F., Clarke, S., Vitetta, L. (2024). An exploratory study of a multi-species probiotic formulation and markers of health in a real-world oncological cohort in the time of covid. Inflammopharmacology. [More Information]
- Vitetta, L., Henson, J. (2024). Comment on “Hall et al., Topical cannabidiol is well tolerated in individuals with a history of elite physical performance and chronic lower extremity pain”. Journal of Cannabis Research, 6(1), 13. [More Information]
- Vitetta, L., Oldfield, D., Sali, A. (2024). Inflammatory Bowel Diseases and the Efficacy of Probiotics as Functional Foods. Frontiers in Bioscience, 16(2). [More Information]
2024
- Thomsen, M., Vemuri, R., Huygens, F., Clarke, S., Vitetta, L. (2024). An exploratory study of a multi-species probiotic formulation and markers of health in a real-world oncological cohort in the time of covid. Inflammopharmacology. [More Information]
- Vitetta, L., Henson, J. (2024). Comment on “Hall et al., Topical cannabidiol is well tolerated in individuals with a history of elite physical performance and chronic lower extremity pain”. Journal of Cannabis Research, 6(1), 13. [More Information]
- Vitetta, L., Oldfield, D., Sali, A. (2024). Inflammatory Bowel Diseases and the Efficacy of Probiotics as Functional Foods. Frontiers in Bioscience, 16(2). [More Information]
2023
- Ritchie, G., Strodl, E., Parham, S., Bambling, M., Cramb, S., Vitetta, L. (2023). An exploratory study of the gut microbiota in major depression with anxious distress. Journal of Affective Disorders, 320, 595-604. [More Information]
- Chen, J., Vitetta, L. (2023). Is miR-223 Upregulation in Inflammatory Bowel Diseases a Protective Response? Frontiers in Bioscience, 15(1). [More Information]
- Vitetta, L. (2023). Letter on “Role of gut microbiome in immune regulation and immune checkpoint therapy of colorectal cancer”. Medical Oncology: a leading journal in clinical oncology, 40(5), 143. [More Information]
2022
- Pickering, E., Steels, E., Steadman, K., Rao, A., Vitetta, L. (2022). A randomized controlled trial assessing the safety and efficacy of palmitoylethanolamide for treating diabetic-related peripheral neuropathic pain. Inflammopharmacology, 30(6), 2063-2077. [More Information]
- Vitetta, L. (2022). Can krill oil from small crustaceans be a panacea that alleviates symptoms of knee osteoarthritis? The American Journal of Clinical Nutrition, 116(3), 621-622. [More Information]
- Vitetta, L., Sikali, J., Fletcher, C., Henson, J. (2022). Comment on: Cannabis use among Danish patients with cancer: a cross‑sectional survey of sociodemographic traits, quality of life, and patient experiences. Supportive Care in Cancer, 30(11), 8619-8621. [More Information]
2021
- Vitetta, L., Butcher, B., Henson, J., Rutolo, D., Hall, S. (2021). A pilot safety, tolerability and pharmacokinetic study of an oro-buccal administered cannabidiol-dominant anti-inflammatory formulation in healthy individuals: a randomized placebo-controlled single-blinded study. Inflammopharmacology, 29(5), 1361-1370. [More Information]
- Chen, J., Hall, S., Vitetta, L. (2021). Altered gut microbial metabolites could mediate the effects of risk factors in Covid-19. Reviews in Medical Virology, 31(5), 1-13. [More Information]
- Chen, J., Vitetta, L. (2021). Commensal bacterial metabolites may strengthen the effect of anti-IL6 treatment for COVID-19. Clinical Immunology, 232, 108870. [More Information]
2020
- Vitetta, L., Butcher, B., Dal Forno, S., Vitetta, G., Nikov, T., Hall, S., Steels, E. (2020). A Double-Blind Randomized Placebo-Controlled Study Assessing the Safety, Tolerability and Efficacy of a Herbal Medicine Containing Pycnogenol Combined with Papain and Aloe vera in the Prevention and Management of Pre-Diabetes. Medicines, 7(4), 1-16. [More Information]
- Chen, J., Vitetta, L. (2020). Butyrate in IBD therapy. Gastroenterology, 158(5), 1511-1513. [More Information]
- Chen, J., Vitetta, L. (2020). Gut microbiota metabolites in nafld pathogenesis and therapeutic implications. International Journal of Molecular Sciences, 21(15), 1-19. [More Information]
2019
- Steels, E., Venkatesh, R., Steels, E., Vitetta, G., Vitetta, L. (2019). A double-blind randomized placebo controlled study assessing safety, tolerability and efficacy of palmitoylethanolamide for symptoms of knee osteoarthritis. Inflammopharmacology, 27(3), 475-485. [More Information]
- Chen, J., Vitetta, L. (2019). Activation of T-regulatory cells by a synbiotic may be important for its anti-inflammatory effect. European Journal of Nutrition, 58(8), 3379-3380. [More Information]
- Chen, J., Vitetta, L. (2019). Bile acids and butyrate in the effects of probiotics/synbiotics on nonalcoholic fatty liver disease. European Journal of Gastroenterology and Hepatology, 31(11), 1475-1476. [More Information]
2018
- Thomsen, M., Vitetta, L. (2018). Adjunctive Treatments for the Prevention of Chemotherapy- and Radiotherapy-Induced Mucositis. Integrative Cancer Therapies, 17(4), 1027-1047. [More Information]
- Vitetta, L., Saltzman, E., Thomsen, M., Nikov, T., Hall, S. (2018). Correction: Vitetta, L; et al Adjuvant Probiotics and the Intestinal Microbiome: Enhancing Vaccines and Immunotherapy Outcomes Vaccines 2017, 5, 50. Vaccines, 6(2), 26. [More Information]
- Vitetta, L., Vitetta, G., Hall, S. (2018). Immunological Tolerance and Function: Associations Between Intestinal Bacteria, Probiotics, Prebiotics, and Phages. Frontiers in Immunology, 9, 1-15. [More Information]
2017
- Bambling, M., Edwards, S., Hall, S., Vitetta, L. (2017). A combination of probiotics and magnesium orotate attenuate depression in a small SSRI resistant cohort: an intestinal anti-inflammatory response is suggested. Inflammopharmacology, 25(2), 271-274. [More Information]
- Schloss, J., Colosimo, M., Airey, C., Masci, P., Linnane, A., Vitetta, L. (2017). A randomised, placebo-controlled trial assessing the efficacy of an oral B group vitamin in preventing the development of chemotherapy-induced peripheral neuropathy (CIPN). Supportive Care in Cancer, 25(1), 195-204. [More Information]
- Vitetta, L., Saltzman, E., Thomsen, M., Nikov, T., Hall, S. (2017). Adjuvant probiotics and the intestinal microbiome: Enhancing vaccines and immunotherapy outcomes. Vaccines, 5(4), 1-17. [More Information]
2016
- Liu, X., Furuya-Kanamori, L., Siskind, D., Crompton, D., Williams, G., Kostner, K., Vitetta, L., Doi, S. (2016). An evidence-based scale for the antecedents of depressive symptoms in Australian adults. Australasian Psychiatry, 24(5), 466-469. [More Information]
- Ellis, R., Small, D., Vesey, D., Johnson, D., Francis, R., Vitetta, L., Gobe, G., Morais, C. (2016). Indoxyl sulphate and kidney disease: causes, consequences and interventions. Nephrology, 21(3), 170-177. [More Information]
- Vitetta, L. (2016). Lactobacillus acidophilus Restores Functionality in Uremic Macrophages: Plausible or Lacking Evidence? Digestive Diseases and Sciences, 61(6), 1417-1419. [More Information]
2015
- Schloss, J., Colosimo, M., Airey, C., Vitetta, L. (2015). Chemotherapy-induced peripheral neuropathy (CIPN) and vitamin B12 deficiency. Supportive Care in Cancer, 23(7), 1843-1850. [More Information]
- Vitetta, L., Palacios, T., Hall, S., Coulson, S. (2015). Gastrointestinal Tract Commensal Bacteria and Probiotics: Influence on End-Organ Physiology. In K D Rainsford, M C Powanda, M W Whitehouse (Eds.), Novel Natural Products:Therapeutic Effects in Pain, Arthritis and Gastro-intestinal Diseases, (pp. 1-33). Basel: Springer. [More Information]
- Rao, A., Steels, E., Beccaria, G., Inder, W., Vitetta, L. (2015). Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study. Phytotherapy Research, 29(8), 1123-1130. [More Information]
2014
- Vitetta, L., Linnane, A. (2014). Endocellular regulation by free radicals and hydrogen peroxide: key determinants of the inflammatory response. Inflammopharmacology, 22(2), 69-72. [More Information]
- Vitetta, L., Hall, S., Linnane, A. (2014). Live probiotic cultures and the gastrointestinal tract: symbiotic preservation of tolerance whilst attenuating pathogenicity. Frontiers in Cellular and Infection Microbiology, 4, 1-5. [More Information]
- Vitetta, L., Briskey, D., Alford, H., Hall, S., Coulson, S. (2014). Probiotics, prebiotics and the gastrointestinal tract in health and disease. Inflammopharmacology, 22(3), 135-154. [More Information]
Selected Grants
2018
- Sense-and-Dispense - breaking barriers in cancer pain treatment using iontophoretic tattoo-like cannabinoids delivery systems., Chrzanowski W, Zhao N, Divakarla S, Vitetta L, Liu J, Chen S, Hall S, Office of Global Engagement/Partnership Collaboration Awards
Conferences
- Alex Seungyeon Byun, Luis Vitetta, Hak-Kim Chan and Philip Chi Lip Kwok.Nebulisation of Lactobacillus rhamnosus GG with vibrating mesh and jet nebulisers. Asian Federation for Pharmaceutical Sciences 2023 | Nov 8-10, 2023, Hanoi Vietnam.
- Henson JD, Vitetta L, Fletcher C, Lu C, Quezada, M Moroni I, Andersen T, Hall S. Can oral administration provide a suitable plasma cannabinoid profile for the effective treatment of chronic pain? IASP World Congress on Pain. Toronto, Canada. 2022.
- Clarke S, Butcher BE, McLachlan AJ, Hendon JD, Rutolo D, Hall S,Vitetta L. Can oral administration provide a suitable plasma cannabinoid profile for the effective treatment of chronic pain? IASP World Congress on Pain 19-23 September 2022, TorontoCanada.
- Sikali JF, Fletcher C, Gillespie A, Hall L, Henson JD, Hall S, Vitetta L, and the Medical Science Liaison Team at Medlab Clinical. An Observational Study Investigating And Auditing The Safety, Tolerability And Further Efficacy Characteristics Of A Pharmaceutical Grade Cannabis-Based Medicine Prescribed To Eligible Patients For The Management Of Cancer Related Or Non-Cancer Related Pain In General And Specialty Medical Practices Australia-Wide. 48th Annual Scientific Meeting COSA 16-18th November, Brisbane 2021.
- Chen J,Vitetta L. Butyrate Sensitizes Epithelioid Mesothelioma Cells to Oxaliplatin. 15th Meeting of the International Mesothelioma Interest Group-Virtual. Poster. In section: Mesothelioma Biology and Novel Targets | 306 (iMig 2021) May 7–9, 2021.
- Clarke S, Butcher B, McLachlan AJ, Henson JD, Rutolo D, Hall S,VitettaL.Can improved mucosal absorption allow a THC/CBD oro-buccal spray to achieve clinical efficacy in chronic pain? ANZCA ASM Poster (Anaesthesia and Pain Medicine in Australia and NewZealand) 30th Apr-4th May Melbourne 2021.
- Vitetta L,Henson HD,Rutolo R, Hall S.An oro-buccal nanoparticle-cannabis delivered medicine for pain management in cancer. 9th Global Nanotechnology Congress and Expo. Miami, Florida, USA. 13-14 Apr 2020.
- Vitetta L, ClarkeS, McLachlanAJ, Henson J, Fletcher C, Vitetta G, Rutolo D, Hall S. A Novel Delivery Mechanism for Cannabinoids in Pain Management. Clinical Oncological Society of Australia Scientific Conference, Adelaide, 12-14 Nov 2019.
- Thomsen M, Vitetta L, Clarke S. Intestinal microbiome and chemotherapy-induced neutropenia. Clinical Oncological Society of Australia Scientific Conference, Adelaide, 12-14 Nov 2019.
- Vitetta L.Mood Disorders and the Brain–Intestinal Mucosa–Appendix–Microbiome–Brain Loop. Keynote Invitation. Probiota Asia Conference, Singapore, 22-24 Oct 2019.
- Palacios T, Vitetta L,Caterson I, Kim JN,Soto-Giron M, Ishoey T, Toledo T, Soto J, Schott EM, Briskey D, Madigan C, Coulson S, Lam Y, Hall S. A randomised controlled pilot study to investigate the effect of a multi-species probiotic formulation and metformin as modulators of the intestinal microbiome for the management of diabetes. Nutrients 2019–In Nutritional Advances in the Prevention and Management of Chronic Disease, Sept 25-27; Barcelona, Spain.
- Vitetta L, Clarke S, Thomsen M. The intestinal microbiome, chemotherapy and adjuvant treatments with probiotics. Asia-Pacific Journal of Clinical Oncology [Clinical Oncological Society of Australia] 2017; Nov 13-15; 13(4):98, ABS#105. Sydney, Australia.
- Palacios T, Vitetta L, Madigan C, Caterson I. Prediabetes and Early Diagnosed T2DM: safety tolerability and pilot exploratory study preliminary results. 5th MICROBIOME R And D And BUSINESS COLLABORATION FORUM: USA COLLABORATIONS IN MICROBIOME RESEARCH, LIVE BACTERIAL THERAPEUTICS, HUMAN HEALTH & DISEASE | 2nd PROBIOTICS CONGRESS: USA. 2-3 Nov 2017. San Diego, USA.
- Vitetta L. Cancer Treatments, the Intestinal Microbiome and Probiotics. IPA World Congress | Asia Probiota. 11-13 Oct 2017. Singapore.
- Palacios T, Vitetta L, Madigan C, Caterson I . The development of a evidence-based probiotic formulation and its efficacy in obesity and type 2 diabetes. 4th Beneficial Microbes Conference, 9-11 Oct 2017. Amsterdam, The Netherlands.
- Kalma B, Ellis RJ, Vitetta L, Wood ST, Gobe GC. Pilot Study: Urinary Indoxyl Sulphate As A Predictor Of Postoperative Kidney Function Following Radical Tumour Nephrectomy. 54th Australian and New Zealand Society of Nephrology. Annual Scientific Meeting 8-12 Sep 2017. Sydney, Australia.
- Vitetta L. The intestinal microbiome, metabolic diseases and probiotics. BIT 15th International Conference: IDDST Jul 26-28 2017. Osaka, Japan.
- Palacios T, Caterson I, Madigan C, Vitetta L. The Efficacy of a Novel Probiotic on Glucose Metabolism: A Randomised Controlled Trial. The 4th Latin American Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension. 16-18 Mar 2017. Buenos Aires, Argentina.
- Chen T, Ellis R, Morais C, Gobe G, Vitetta L. Nephrotoxic effects of cis-diamminedichloroplatinium II (cisplatin) can be ameliorated using Coenzyme Q10 (CoQ10), 7th World Congress on Targeting Mitochondria. Oct 24–26, 2016. Berlin, Germany.
- Palacios T, Vitetta L, Coulson S, Butt H, Caterson I. The Effect of a Multi-Strain Probiotic on Metabolic Bio-Markers in Adults with Prediabetes and Recently Diagnosed Type 2 Diabetes Mellitus (T2DM). ICO May 1-4, 2016, Vancouver, Canada.
- Vitetta L. Reactive oxygen species and their lifelong regulation of the metabolome. 6th World Congress on Targeting Mitochondria. Oct 28–30, 2015. Berlin, Germany.
- RJ Ellis, DM Small, KL Ng, DA Vesey, L Vitetta, R Francis, C Morais, GC Gobe. Indoxyl Sulphate Induces Hypertrophy and Impaired Metabolic Activity In Cultured Human Proximal Tubular Cells. Aust New Zealand Soc of Nephrol (Annual Scientific Meeting) 2015; Sep 7–9. Canberra, Australia.
- Briskey D, Peake J, Coulson S, Vitetta L. High Fat Diet, Probiotics and Non–Alcoholic Fatty Liver Disease 4th Beneficial Microbes Conference, The Hague, Netherlands, 2015, 75, P25.
- Rao A, Steels E, Vitetta L, Inder W, Beccaria G. Influence of a specialized Trigonella foenum-graecum seed extract (Libifem), on testosterone, estradiol and sexual function, a randomized placebo-controlled study. 25th Annual Meeting of The North American Menopause Society October 15–October 18, 2014, Washington, DC. In: Menopause 21(12):1360-1361.
- Rao A, Steels E, Vitetta L, Inder W, Beccaria G. Influence of a specialized Trigonella foenum-graecum seed extract (Libifem), on testosterone, estradiol and sexual function, a randomized placebo-controlled study. 25th Annual Meeting of The North American Menopause Society October 15–October 18, 2014, Washington, DC. In: Menopause 21(12):1360-1361.
- Marx W, Ried K, Mckavanagh D, Vitetta L, Sali S, Isenring L. Ginger as an adjuvant for chemotherapy-induced nausea and vomiting: where does the evidence stand? Asia Pacific Journal of Clinical Oncology 2014;10:115-116.
- Schloss J, Colosimo M, Airey C, Masci PP, Linnane AW, Vitetta L.B complex vitamins reduce the onset and severity of chemotherapy inducedsensory peripheral neuropathy. 7th International Conference and Exhibition on Nutraceuticals and Functional Foods. October 14-17, 2014, Istanbul, Turkey.
- Vitetta L. Probiotics, the gastrointestinal tract microbiome and musculoskeletal diseases. International Probiotic Association World Congress. May 9-10, 2014, Athens, Greece. In: Beneficial Microbes 5 (Suppl 1): 23.
- Vitetta L. The gastrointestinal tract microbiome and the metabolism of herbal compounds such as trigonella foenum-graecum extract. The 4th International Symposium on Curry and Spice (April 24, 2014) in Seoul, South Korea.