Dr Matteo Carlino
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Dr Matteo Carlino

Clinical Associate Professor
Sydney Medical School's Education Office
Faculty of Medicine and Health

Publications

Book Chapters

  • Gowrishankar, K., Carlino, M., Rizos, H. (2013). Acquired Resistance to Targeted MAPK Inhibition in Melanoma. In Guy Huynh Thien Duc (Eds.), Melanoma - From Early Detection to Treatment, (pp. 197-218). Croatia: InTech Publishers. [More Information]

Journals

  • Gunjur, A., Underhill, C., Frentzas, S., Michael, M., Gao, B., Palmer, J., Cebon, J., Behren, A., Adams, D., Lawley, T., Carlino, M., et al (2024). A gut microbial signature for combination immune checkpoint blockade across cancer types. Nature Medicine. [More Information]
  • Gjorup, C., Woodford, R., Li, I., Carlino, M., Ch'ng, S., Chung, D., Hsiao, E., Lo, S., London, K., Long, G., Menzies, A., Nieweg, O., Pennington, T., Rtshiladze, M., Saw, R., Scolyer, R., Shannon, K., Spillane, A., Stretch, J., Thompson, J., Varey, A., van Akkooi, A. (2024). ASO Visual Abstract: Role of Concurrent Ultrasound Surveillance of Sentinel Node‑Positive Node Fields in Melanoma Patients Having Routine Cross‑Sectional Imaging. Annals of Surgical Oncology, 31(3), 1882-1883. [More Information]
  • Wu, L., Tsang, V., Gunton, J., Carlino, M., Brown, D., Long, G., Clifton-Bligh, R., Mellor, R., Moore, K., Sasson, S., Menzies, A. (2024). Checkpoint Inhibitor-Associated Autoimmune Diabetes Mellitus Is Characterized by C-peptide Loss and Pancreatic Atrophy. Journal of Clinical Endocrinology and Metabolism, 109(5), 1301-1307. [More Information]

2024

  • Gunjur, A., Underhill, C., Frentzas, S., Michael, M., Gao, B., Palmer, J., Cebon, J., Behren, A., Adams, D., Lawley, T., Carlino, M., et al (2024). A gut microbial signature for combination immune checkpoint blockade across cancer types. Nature Medicine. [More Information]
  • Gjorup, C., Woodford, R., Li, I., Carlino, M., Ch'ng, S., Chung, D., Hsiao, E., Lo, S., London, K., Long, G., Menzies, A., Nieweg, O., Pennington, T., Rtshiladze, M., Saw, R., Scolyer, R., Shannon, K., Spillane, A., Stretch, J., Thompson, J., Varey, A., van Akkooi, A. (2024). ASO Visual Abstract: Role of Concurrent Ultrasound Surveillance of Sentinel Node‑Positive Node Fields in Melanoma Patients Having Routine Cross‑Sectional Imaging. Annals of Surgical Oncology, 31(3), 1882-1883. [More Information]
  • Wu, L., Tsang, V., Gunton, J., Carlino, M., Brown, D., Long, G., Clifton-Bligh, R., Mellor, R., Moore, K., Sasson, S., Menzies, A. (2024). Checkpoint Inhibitor-Associated Autoimmune Diabetes Mellitus Is Characterized by C-peptide Loss and Pancreatic Atrophy. Journal of Clinical Endocrinology and Metabolism, 109(5), 1301-1307. [More Information]

2023

  • Piperno-Neumann, S., Carlino, M., Boni, V., Loirat, D., Speetjens, F., Park, J., Calvo, E., Carvajal, R., Nyakas, M., Gonzalez-Maffe, J., et al (2023). A phase I trial of LXS196, a protein kinase C (PKC) inhibitor, for metastatic uveal melanoma. British Journal of Cancer, 128(6), 1040-1051. [More Information]
  • Weber, J., Schadendorf, D., Del Vecchio, M., Larkin, J., Atkinson, V., Schenker, M., Pigozzo, J., Gogas, H., Dalle, S., Meyer, N., Carlino, M., Menzies, A., et al (2023). Adjuvant Therapy of Nivolumab Combined with Ipilimumab Versus Nivolumab Alone in Patients with Resected Stage IIIB-D or Stage IV Melanoma (CheckMate 915). Journal of Clinical Oncology, 41(3), 517-527. [More Information]
  • Lee, J., Ahmed, T., Maurichi, A., Di Guardo, L., Stagno, A., Warburton, L., Taylor, A., Livingstone, E., Rehman, S., Khattak, A., Lo, S., Long, G., Menzies, A., Carlino, M., et al (2023). BRAF inhibitor cessation prior to disease progression in metastatic melanoma: Long-term outcomes. European Journal of Cancer, 179, 87-97. [More Information]

2022

  • Khattak, M., Luke, J., Long, G., Ascierto, P., Rutkowski, P., Schadendorf, D., Robert, C., Grob, J., de la Cruz Merino, L., Del Vecchio, M., Carlino, M., et al (2022). Adjuvant pembrolizumab versus placebo in resected high-risk stage II melanoma: Health-related quality of life from the randomized phase 3 KEYNOTE-716 study. European Journal of Cancer, 176, 207-217. [More Information]
  • Diefenbach, R., Lee, J., Stewart, A., Menzies, A., Carlino, M., Saw, R., Stretch, J., Long, G., Scolyer, R., Rizos, H. (2022). Anchored Multiplex PCR Custom Melanoma Next Generation Sequencing Panel for Analysis of Circulating Tumor DNA. Frontiers in Oncology, 12, 820510. [More Information]
  • Long, G., Arance, A., Mortier, L., Lorigan, P., Blank, C., Mohr, P., Schachter, J., Grob, J., Lotem, M., Middleton, M., Carlino, M., et al (2022). Antitumor activity of ipilimumab or BRAF ± MEK inhibition after pembrolizumab treatment in patients with advanced melanoma: analysis from KEYNOTE-006. Annals of Oncology, 33(2), 204-215. [More Information]

2021

  • Randall Patrinely, J., Funck-Brentano, E., Nguyen, K., Rapisuwon, S., Salem, J., Gibney, G., Carlino, M., Johnson, D. (2021). A Multicenter Analysis of Immune Checkpoint Inhibitors as Adjuvant Therapy Following Treatment of Isolated Brain Metastasis. The Oncologist, 26(3), e505-e507. [More Information]
  • Livingstone (nee Ratcliffe), A., Dempsey, K., Stockler, M., Howard, K., Long, G., Carlino, M., Menzies, A., Morton, R. (2021). Adjuvant immunotherapy recommendations for stage III melanoma: physician and nurse interviews. BMC Cancer, 21(1), 1014. [More Information]
  • Bottomley, A., Coens, C., Mierzynska, J., Blank, C., Mandalà, M., Long, G., Atkinson, V., Dalle, S., Haydon, A., Meshcheryakov, A., Carlino, M., et al (2021). Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): health-related quality-of-life results from a double-blind, randomised, controlled, phase 3 trial. The Lancet Oncology, 22(5), 655-664. [More Information]

2020

  • Sullivan, R., Weber, J., Patel, S., Dummer, R., Carlino, M., Tan, D., Lebbé, C., Siena, S., Elez, E., Wollenberg, L., et al (2020). A Phase Ib/II Study of the BRAF Inhibitor Encorafenib plus the MEK Inhibitor Binimetinib in Patients with BRAFV600E/K-mutant Solid Tumors. Clinical Cancer Research, 26(19), 5102-5112. [More Information]
  • Eggermont, A., Kicinski, M., Blank, C., Mandalà, M., Long, G., Atkinson, V., Dalle, S., Haydon, A., Khattak, A., Carlino, M., et al (2020). Association between Immune-Related Adverse Events and Recurrence-Free Survival among Patients with Stage III Melanoma Randomized to Receive Pembrolizumab or Placebo: A Secondary Analysis of a Randomized Clinical Trial. JAMA Oncology, 6(4), 519-527. [More Information]
  • Puzanov, I., Ribas, A., Robert, C., Schachter, J., Nyakas, M., Daud, A., Arance, A., Carlino, M., O'Day, S., Long, G., et al (2020). Association of BRAF V600E/K Mutation Status and Prior BRAF/MEK Inhibition with Pembrolizumab Outcomes in Advanced Melanoma: Pooled Analysis of 3 Clinical Trials. JAMA Oncology, 6(8), 1256-1264. [More Information]

2019

  • Diefenbach, R., Lee, J., Strbenac, D., Yang, J., Menzies, A., Carlino, M., Long, G., Spillane, A., Stretch, J., Saw, R., Thompson, J., Ch'ng, S., Scolyer, R., Kefford, R., Rizos, H. (2019). Analysis of the whole-exome sequencing of tumor and circulating tumor DNA in metastatic melanoma. Cancers, 11(12), 1-14. [More Information]
  • Lim, S., Lee, J., Gide, T., Menzies, A., Guminski, A., Carlino, M., Breen, E., Yang, J., Ghazanfar, S., Kefford, R., Scolyer, R., Long, G., Rizos, H. (2019). Circulating Cytokines Predict Immune-Related Toxicity in Melanoma Patients Receiving Anti-PD-1–Based Immunotherapy. Clinical Cancer Research, 25(5), 1557-1563. [More Information]
  • Ribas, A., Lawrence, D., Atkinson, V., Agarwal, S., Miller Jr, W., Carlino, M., Fisher, R., Long, G., Hodi, F., Tsoi, J., et al (2019). Combined BRAF and MEK inhibition with PD-1 blockade immunotherapy in BRAF-mutant melanoma. Nature Medicine, 25(6), 936?940. [More Information]

2018

  • Eggermont, A., Blank, C., Mandala, M., Long, G., Atkinson, V., Dalle, S., Haydon, A., Lichinitser, M., Khattak, A., Khattak, M., Carlino, M., et al (2018). Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma. New England Journal of Medicine, 378(19), 1789-1801. [More Information]
  • Kugel III, C., Douglass, S., Webster, M., Kaur, A., Liu, Q., Yin, X., Weiss, S., Darvishian, F., Al-Rohil, R., Ndoye, A., Rai, R., Carlino, M., Long, G., Menzies, A., et al (2018). Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations. Clinical Cancer Research, 24(21), 5347-5356. [More Information]
  • Lee, J., Long, G., Menzies, A., Lo, S., Guminski, A., Whitbourne, K., Peranec, M., Scolyer, R., Kefford, R., Rizos, H., Carlino, M. (2018). Association Between Circulating Tumor DNA and Pseudoprogression in Patients With Metastatic Melanoma Treated With Anti-Programmed Cell Death 1 Antibodies. JAMA Oncology, 4(5), 717-721. [More Information]

2017

  • Hwang, S., Wakade, D., Kong, B., Carlino, M., Chou, S., Fernandez Penas, P. (2017). Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like Cellulitis. Case Reports in Medicine, 2017, 1-3. [More Information]
  • Menzies, A., Johnson, D., Ramanujam, S., Atkinson, V., Wong, A., Park, J., McQuade, J., Shoushtari, A., Tsai, K., Eroglu, Z., Guminski, A., Carlino, M., Long, G., et al (2017). Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab. Annals of Oncology, 28(2), 368-376. [More Information]
  • Lee, J., Long, G., Boyd, S., Lo, S., Menzies, A., Tembe, V., Guminski, A., Jakrot, V., Scolyer, R., Mann, G., Kefford, R., Carlino, M., Rizos, H. (2017). Circulating tumour DNA predicts response to anti-PD1 antibodies in metastatic melanoma. Annals of Oncology, 28(5), 1130-1136. [More Information]

2016

  • Liniker, E., Menzies, A., Kong, B., Cooper, A., Ramanujam, S., Lo, S., Kefford, R., Fogarty, G., Guminski, A., Wang, T., Carlino, M., Hong, A., Long, G. (2016). Activity and safety of radiotherapy with anti-PD-1 drug therapy in patients with metastatic melanoma. OncoImmunology, 5(9), 1-7. [More Information]
  • Janssen, A., Shaw, T., Nagrial, A., Pene, C., Rabbets, M., Carlino, M., Zachulski, C., Phillips, J., Birnbaum, R., Gandhi, T., Harnett, P. (2016). An Online Learning Module to Increase Self-Efficacy and Involvement in Care for Patients With Advanced Lung Cancer: Research Protocol. Journal of Medical Internet Research, 5(3), 1-8. [More Information]
  • Kong, B., Micklethwaite, K., Swaminathan, S., Kefford, R., Carlino, M. (2016). Autoimmune hemolytic anemia induced by anti-PD-1 therapy in metastatic melanoma. Melanoma Research, 26(2), 202-204. [More Information]

2015

  • Chan, M., Kefford, R., Carlino, M., Clements, A., Manolios, N. (2015). Arthritis and Tenosynovitis Associated With the Anti-PD1 Antibody Pembrolizumab in Metastatic Melanoma. Journal of Immunotherapy, 38(1), 37-39. [More Information]
  • Gray, E., Rizos, H., Reid, A., Boyd, S., Pereira, M., Lo, J., Tembe, V., Freeman, J., Lee, J., Scolyer, R., Long, G., Carlino, M., et al (2015). Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma. Oncotarget, 6(39), 42008-42018. [More Information]
  • Menzies, A., Wilmott, J., Drummond, M., Lo, S., Lyle, M., Chan, M., Thompson, J., Guminski, A., Carlino, M., Scolyer, R., Kefford, R., Long, G. (2015). Clinicopathologic features associated with efficacy and long-term survival in metastatic melanoma patients treated with BRAF or combined BRAF and MEK inhibitors. Cancer, 121(21), 3826-3835. [More Information]

2014

  • Rizos, H., Menzies, A., Pupo, G., Carlino, M., Fung, C., Hyman, J., Haydu, L., Mijatov, B., Becker, T., Boyd, S., Howle, J., Saw, R., Thompson, J., Kefford, R., Scolyer, R., Long, G. (2014). BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact. Clinical Cancer Research, 20(7), 1965-1977. [More Information]
  • Carlino, M., Haydu, L., Kakavand, H., Menzies, A., Hamilton, A., Yu, B., Ng, C., Cooper, W., Thompson, J., Kefford, R., O'Toole, S., Scolyer, R., Long, G. (2014). Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma. British Journal of Cancer, 111(2), 292-299. [More Information]
  • Carlino, M., Todd, J., Gowrishankar, K., Mijatov, B., Pupo, G., Fung, C., Snoyman, S., Hersey, P., Long, G., Kefford, R., Rizos, H. (2014). Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma. Molecular Oncology, 8(3), 544-554. [More Information]

2013

  • Carlino, M., Saunders, C., Haydu, L., Menzies, A., Curtis, C., Lebowitz, P., Kefford, R., Long, G. (2013). 18F-labelled fluorodeoxyglucose-positron emission tomography (FDG-PET) heterogeneity of response is prognostic in dabrafenib treated BRAF mutant metastatic melanoma. European Journal of Cancer, 49(2), 395-402. [More Information]
  • Gowrishankar, K., Carlino, M., Rizos, H. (2013). Acquired Resistance to Targeted MAPK Inhibition in Melanoma. In Guy Huynh Thien Duc (Eds.), Melanoma - From Early Detection to Treatment, (pp. 197-218). Croatia: InTech Publishers. [More Information]
  • Carlino, M., Gowrishankar, K., Saunders, C., Pupo, G., Snoyman, S., Zhang, X., Saw, R., Becker, T., Kefford, R., Long, G., Rizos, H. (2013). Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma. Molecular Cancer Therapeutics, 12(7), 1332-1342. [More Information]

2012

  • Menzies, A., Haydu, L., Visintin, L., Carlino, M., Howle, J., Thompson, J., Kefford, R., Scolyer, R., Long, G. (2012). Distinguishing Clinicopathologic Features of Patients with V600E and V600K BRAF-Mutant Metastatic Melanoma. Clinical Cancer Research, 18(12), 3242-3249. [More Information]
  • Carlino, M., Fogarty, G., Long, G. (2012). Treatment of Melanoma Brain Metastases: A New Paradigm. The Cancer Journal, 18(2), 208-212. [More Information]

Selected Grants

2021

  • NADINA Phase 3 trial comparing response driven neo-adjuvant combination of ipilimumab nivolumab versus adjuvant nivolumab, Long G, Scolyer R, McArthur G, Menzies A, Spillane A, Carlino M, Gyorki D, Saw R, Lo S, Morton R, Department of Health and Aged Care (Federal - administered by NHMRC)/2020 Efficient Use of Existing Medicines

2020

  • Circulating tumour DNA guidEd Therapy for stage IIB/C BRAF mutant positive mElanoma after surgiCal resecTION (DETECTION), Long G, Carlino M, Menzies A, Scolyer R, Department of Health and Aged Care (Federal)/MRFF - International Clinical Trials Collaborations Program