2024

• O'Hehir, Z., Lynch, T., O'Neill, S., March, L., Xue, M. (2024). Endothelial Protein C Receptor and Its Impact on Rheumatic Disease. Journal of Clinical Medicine, 13(7), 2030. [More Information]

2023

• Roche, C., Lin, H., Huang, Y., de Bock, C., Beck, D., Xue, M., Gentile, C. (2023). 3D bioprinted alginate-gelatin hydrogel patches containing cardiac spheroids recover heart function in a mouse model of myocardial infarction. Bioprinting, 30. [More Information]

2022

• Xue, M., Lin, H., Zhao, R., Fryer, C., March, L., Jackson, C. (2022). Activated Protein C Protects against Murine Contact Dermatitis by Suppressing Protease-Activated Receptor 2. International Journal of Molecular Sciences, 23(1), 516. [More Information]
• Xue, M., Zhao, R., March, L., Jackson, C. (2022). Dermal Fibroblast Heterogeneity and Its Contribution to the Skin Repair and Regeneration. Advances in Wound Care, 11(2), 87-107. [More Information]

2021

• Sammel, A., Xue, M., Karsten, E., Little, C., Smith, S., Nguyen, K., Laurent, R. (2021). Limited utility of novel serological biomarkers in patients newly suspected of having giant cell arteritis. International Journal of Rheumatic Diseases, 24(6), 781-788. [More Information]
• Roche, C., Sharma, P., Ashton, A., Jackson, C., Xue, M., Gentile, C. (2021). Printability, Durability, Contractility and Vascular Network Formation in 3D Bioprinted Cardiac Endothelial Cells Using Alginate-Gelatin Hydrogels. Frontiers in Bioengineering and Biotechnology, 9, 636257-1-636257-14. [More Information]
• Orsmond, A., Bereza-Malcolm, L., March, L., Xue, M., Lynch, T. (2021). Skin barrier dysregulation in psoriasis. International Journal of Molecular Sciences, 22(19), 10841-1-10841-27. [More Information]
• Jackson, C., Xue, M. (2021). An agent that prevents/treats the abnormal cutaneous scaring. Patent No. 2014391082, 3137102, 6846063, ZL201480078924.1. , China.
• Xue, M., Jackson, C. (2021). An agent that treats skin ulcers. Patent No. 2015246656, 3131552, 6873387, ZL201580025422.7. , China.

2020

• Jackson, C., Xue, M. (2020). Treatment for Inflammatory Skin Diseases. Patent No. 10-2068010, 2013286812, 2662564, 2869833, 6273272, HK1204573, ZL201380034024.2. , Belgium, China, France, Germany, Hong Kong, Ireland, Italy, Korea (South), Netherlands, Russian Federation, Spain, Switzerland, United Kingdom.

2019

• Lang, T., Zhao, R., Kim, A., Wijewardena, A., Vandervord, J., Xue, M., Jackson, C. (2019). A Critical Update of the Assessment and Acute Management of Patients with Severe Burns. Advances in Wound Care, 8(12), 607-633. [More Information]
• Zhao, R., Lin, H., Bereza-Malcolm, L., Clarke, E., Jackson, C., Xue, M. (2019). Activated Protein C in Cutaneous Wound Healing: From Bench to Bedside. International Journal of Molecular Sciences, 20(4), 1-20. [More Information]
• Xue, M., Dervish, S., McKelvey, K., March, L., Wang, F., Little, C., Jackson, C. (2019). Activated protein C targets immune cells and rheumatoid synovial fibroblasts to prevent inflammatory arthritis in mice. Rheumatology, 58(10), 1850-1860. [More Information]
• Peng, Q., Luo, A., Zhou, Z., Xuan, W., Qiu, M., Wu, Q., Xu, L., Kong, X., Zhang, M., Tan, W., Xue, M., et al (2019). Interleukin 29 inhibits RANKL-induced osteoclastogenesis via activation of JNK and STAT, and inhibition of NF-kappa B and NFATc1. Cytokine, 113, 144-154. [More Information]

2018

• Xue, M., Zhao, R., Lin, H., Jackson, C. (2018). Delivery systems of current biologicals for the treatment of chronic cutaneous wounds and severe burns. Advanced Drug Delivery Reviews, 129, 219-241. [More Information]
• Xue, M., Jackson, C., Dervish, S. (2018). Isolation of Human Skin Epidermal Stem Cells Based on the Expression of Endothelial Protein C Receptor. Methods in Molecular Biology, 1879, 165-174. [More Information]
• Beserra, F., Xue, M., Maia, G., Rozza, A., Pellizzon, C., Jackson, C. (2018). Lupeol, a Pentacyclic Triterpene, Promotes Migration, Wound Closure, and Contractile Effect In Vitro: Possible Involvement of PI3K/Akt and p38/ERK/MAPK Pathways. Molecules, 23(11), 1-17. [More Information]

2017

• Minhas, N., Xue, M., Jackson, C. (2017). Activated protein C binds directly to Tie2: possible beneficial effects on endothelial barrier function. Cellular and Molecular Life Sciences, 74(10), 1895-1906. [More Information]
• Xue, M., Lin, H., Zhao, R., Liang, H., Jackson, C. (2017). The differential expression of protease activated receptors contributes to functional differences between dark and fair keratinocytes. Journal of Dermatological Science, 85(3), 178-185. [More Information]
• Xue, M., Dervish, S., Chan, B., Jackson, C. (2017). The Endothelial Protein C Receptor Is a Potential Stem Cell Marker for Epidermal Keratinocytes. Stem Cells, 35(7), 1786-1798. [More Information]
• Kim, A., Lang, T., Xue, M., Wijewardana, A., Jackson, C., Vandervord, J. (2017). The role of Th-17 cells and (gamma)(delta) T-cells in modulating the systemic inflammatory response to severe burn injury. International Journal of Molecular Sciences, 18(4), 1-6. [More Information]

2016

• Nguyen, T., McKelvey, K., March, L., Hunter, D., Xue, M., Jackson, C., Morris, J. (2016). Aberrant levels of natural IgM antibodies in osteoarthritis and rheumatoid arthritis patients in comparison to healthy controls. Immunology Letters, 170, 27-36. [More Information]
• Zhao, R., Liang, H., Clarke, E., Jackson, C., Xue, M. (2016). Inflammation in Chronic Wounds. International Journal of Molecular Sciences, 17(12), 1-14. [More Information]
• Xu, L., Peng, Q., Xuan, W., Feng, X., Kong, X., Zhang, M., Tan, W., Xue, M., Wang, F. (2016). Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis. Mediators of Inflammation, 2016, 1-13. [More Information]

2015

• Xue, M., Jackson, C. (2015). Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring. Advances in Wound Care, 4(3), 119-136. [More Information]
• Xue, M., Jackson, C. (2015). Novel Functions of the Anticoagulant Activated Protein C in Maintaining Skin Barrier Integrity to Impact on Skin Disease. Pathobiology: exploring the basis of disease, 82(2), 100-106. [More Information]
• Whitmont, K., McKelvey, K., Fulcher, G., Reid, I., March, L., Xue, M., Cooper, A., Jackson, C. (2015). Treatment of chronic diabetic lower leg ulcers with activated protein C: a randomised placebo-controlled, double-blind pilot clinical trial. International Wound Journal, 12(4), 422-427. [More Information]

2014

• Shen, K., Murphy, C., Chan, B., Kolind, M., Cheng, T., Cheng, T., Mikulec, K., Peacock, L., Xue, M., Park, S., Little, D., Jackson, C., Schindeler, A. (2014). Activated Protein C (APC) can Increase Bone Anabolism via a Protease Activated Receptor (PAR)1/2 Dependent Mechanism. Journal of Orthopaedic Research, 32(12), 1549-1556. [More Information]
• Xue, M., Jackson, C. (2014). Activated Protein C and its Potential Applications in Prevention of Islet B-cell Damage and Diabetes. In Gerald Litwack (Eds.), Vitamins and Hormones: The Pancreatic Beta Cell, (pp. 323-363). London: Elsevier. [More Information]
• McKelvey, K., Jackson, C., Xue, M. (2014). Activated protein C: A regulator of human skin epidermal keratinocyte function. World Journal of Biological Chemistry, 5(2), 169-179. [More Information]
• Xue, M., McKelvey, K., Shen, K., Minhas, N., March, L., Park, S., Jackson, C. (2014). Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation. Rheumatology, 53(12), 2270-2279. [More Information]
• Xue, M., Shen, K., McKelvey, K., Li, J., Chan, Y., Hatzis, V., March, L., Little, C., Tonkin, M., Jackson, C. (2014). Endothelial protein C receptor associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A2. Arthritis Research and Therapy, 16(1), 1-12. [More Information]

2013

• Lee, Y., Jeong, J., Seol, J., Xue, M., Jackson, C., Park, S. (2013). Activated protein C differentially regulates both viability and differentiation of osteoblasts mediated by bisphosphonates. Experimental and Molecular Medicine, 45, 1-7. [More Information]
• Akbari, M., Dadadashian, F., Kordestani, S., Xue, M., Jackson, C. (2013). Enzymatic modification of regenerated cellulosic fabrics to improve bacteria sorption properties. Journal of Biomedical Materials Research A, 101A (6), 1734-1742. [More Information]
• Whitmont, K., Fulcher, G., Reid, I., Xue, M., McKelvey, K., Xie, Y., Aboud, M., Ward, C., Smith, M., Cooper, A., March, L., Jackson, C. (2013). Low Circulating Protein C Levels Are Associated with Lower Leg Ulcers in Patients with Diabetes. BioMed Research International, 2013, 1-4. [More Information]

2012

• Xue, M., Dervish, S., Harrison, L., Fulcher, G., Jackson, C. (2012). Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice. Journal of Biological Chemistry, 287(20), 16356-16364. [More Information]
• McKelvey, K., Xue, M., Whitmont, K., Shen, K., Cooper, A., Jackson, C. (2012). Potential anti-inflammatory treatments for chronic wounds. Wound Practice & Research, 20(2), 86-89.
• Xue, M., Chan, A., Shen, K., Dervish, S., March, L., Sambrook, P., Jackson, C. (2012). Protease-Activated Receptor 2, Rather Than Protease-Activated Receptor 1, Contributes to the Aggressive Properties of Synovial Fibroblasts in Rheumatoid Arthritis. Arthritis & Rheumatology, 64(1), 88-98. [More Information]

2011

• Xue, M., Chow, S., Dervish, S., Chan, Y., Julovi, S., Jackson, C. (2011). Activated Protein C Enhances Human Keratinocyte Barrier Integrity via Sequential Activation of Epidermal Growth Factor Receptor and Tie2. Journal of Biological Chemistry, 286(8), 6742-6750. [More Information]
• Jackson, C., Xue, M. (2011). Anti-Inflammatory Actions of the Anticoagulant, Activated Protein C. In Amit Nagal (Eds.), Inflammatory Diseases - A Modern Perspective, (pp. 45-72). Rijeka: InTech Publishers. [More Information]
• Moon, M., Jeong, J., Seo, J., Seol, J., Lee, Y., Xue, M., Jackson, C., Park, S. (2011). Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation. Experimental and Molecular Medicine, 43(3), 138-145. [More Information]
• Julovi, S., Xue, M., Dervish, S., Sambrook, P., March, L., Jackson, C. (2011). Protease Activated Receptor-2 Mediates Activated Protein C-Induced Cutaneous Wound Healing via Inhibition of p38. American Journal of Pathology, 179(5), 2233-2242. [More Information]

2010

• Minhas, N., Xue, M., Fukudome, K., Jackson, C. (2010). Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function. The FASEB Journal, 24(3), 873-881. [More Information]
• Xue, M., Minhas, N., Chow, S., Dervish, S., Sambrook, P., March, L., Jackson, C. (2010). Endogenous protein C is essential for the functional integrity of human endothelial cells. Cellular and Molecular Life Sciences, 67(9), 1537-1546. [More Information]

2009

• Xue, M., Smith, M., Little, C., Sambrook, P., March, L., Jackson, C. (2009). Activated protein C mediates a healing phenotype in cultured tenocytes. Journal of Cellular and Molecular Medicine, 13(4), 749-757. [More Information]
• Jackson, M., Smith, M., Smith, S., Jackson, C., Xue, M., Little, C. (2009). Activation of Cartilage Matrix Metalloproteinases by Activated Protein C. Arthritis & Rheumatology, 60(3), 780-791. [More Information]
• Xue, A., Xue, M., Jackson, C., Smith, R. (2009). Suppression of urokinase plasminogen activator receptor inhibits proliferation and migration of pancreatic adenocarcinoma cells via regulation of ERK/p38 signaling. International Journal of Biochemistry and Cell Biology, 41(8-9), 1731-1738. [More Information]

2008

• Jackson, C., Xue, M. (2008). Activated protein C-An anticoagulant that does more than stop clots. International Journal of Biochemistry and Cell Biology, 40(12), 2692-2697. [More Information]
• Xue, M., Jackson, C. (2008). Autocrine Actions of Matrix Metalloproteinase (MMP)-2 Counter the Effects of MMP-9 to Promote Survival and Prevent Terminal Differentiation of Cultured Human Keratinocytes. Journal of Investigative Dermatology, 128(11), 2676-2685. [More Information]
• Jackson, C., Whitmont, K., Tritton, S., March, L., Sambrook, P., Xue, M. (2008). New therapeutic applications for the anticoagulant, activated protein C. Expert Opinion on Biological Therapy, 8(8), 1109-1122. [More Information]
• Wang, W., Xue, M., Willcox, M., Thakur, A. (2008). Role of Nitric Oxide in P. aeruginosa Keratitis Caused by Distinct Bacterial Phenotypes. Eye and Contact Lens, 34(4), 195-197. [More Information]
• Whitmont, K., Reid, I., Tritton, S., March, L., Xue, M., Lee, M., Fulcher, G., Sambrook, P., Slobedman, E., Cooper, A., Jackson, C. (2008). Treatment of chronic leg ulcers with topical activated protein C. Archives of Dermatology, 144(11), 1479-1483. [More Information]

2007

• Xue, M., Thakur, A., Cole, N., Lloyd, A., Stapleton, F., Wakefield, D., Willcox, M. (2007). A critical role for CCL2 and CCL3 chemokines in the regulation of polymorphonuclear neutrophils recruitment during corneal infection in mice. Immunology and Cell Biology, 85(7), 525-531. [More Information]
• Xue, M., March, L., Sambrook, P., Jackson, C. (2007). Differential Regulation of Matrix Metalloproteinase 2 and Matrix Metalloproteinase 9 by Activated Protein C: Relevance to Inflammation in Rheumatoid Arthritis. Arthritis & Rheumatology, 56(9), 2864-2874. [More Information]
• Xue, M., March, L., Sambrook, P., Fukudome, K., Jackson, C. (2007). Endothelial protein C receptor is over-expressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes. Annals of the Rheumatic Diseases, 66(12), 1574-1580. [More Information]
• Xue, M., Campbell, D., Jackson, C. (2007). Protein C is an autocrine growth factor for human skin keratinocytes. Journal of Biological Chemistry, 282(18), 13610-13616. [More Information]
• Le, N., Xue, M., Castelnoble, L., Jackson, C. (2007). The dual personalities of matrix metalloproteinases in inflammation. Frontiers in Bioscience, 12, 1475-1487. [More Information]

2006

• Jackson, C., Xue, M. (2006). Activated protein C (APC) as a novel agent to promote wound healing. Primary Intention, 14(1), 31-34.
• Xue, M., Thompson, P., Sambrook, P., March, L., Jackson, C. (2006). Activated protein C stimulates expression of angiogenic factors in human skin cells,angiogenesis in the chick embryo and cutaneous wound healing in rodents. Clinical Hemorheology and Microcirculation, 34, 153-161. [More Information]
• Little, C., Jackson, M., Smith, M., Burkhardt, D., Xue, M., Jackson, C. (2006). Potential role of activated protein C (APC) in articular cartilage degeneration. 49th Annual Meeting of the Orthopaedic Research Society, United states: Orthopaedic Research Society.
• Xue, M., Jackson, C., Le, N. (2006). Targeting matrix metalloproteases to improve cutaneous wound healing. Expert Opinion on Therapeutic Targets, 10(1), 143-155. [More Information]

2005

• Jackson, C., Xue, M., Thompson, P., Davey, R., Whitmont, K., Smith, S., Buisson-Legendre, N., Sztynda, T., Furphy, L., Cooper, A., Sambrook, P., March, L. (2005). Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing. Wound Repair and Regeneration, 13(3), 284-294. [More Information]
• Xue, M., Campbell, D., Sambrook, P., Fukudome, K., Jackson, C. (2005). Endothelial Protein C Receptor and Protease-Activated Receptor-1 Mediate Induction of a Wound-Healing Phenotype in Human Keratinocytes by Activated Protein C. Journal of Investigative Dermatology, 125(6), 1279-1285. [More Information]
• Xue, M., Thompson, P., Clifton-Bligh, R., Fulcher, G., Gallery, E., Jackson, C. (2005). Leukocyte matrix metalloproteinase-9 is elevated and contributes to lymphocyte activation in type I diabetes. International Journal of Biochemistry and Cell Biology, 37(11), 2406-2416. [More Information]

2004

• Xue, M., Thompson, P., Kelso, I., Jackson, C. (2004). Activated Protein C Stimulates Proliferation, Migration And Wound Closure, Inhibits Apoptosis And Upregulates Mmp-2 Activity In Cultured Human Keratinocytes. Experimental Cell Research, 299(1), 119-127. [More Information]