2024

• Ruiz-Lozano, R., Calvo-Gallego, J., Pivonka, P., Mcdonald, M., Martínez-Reina, J. (2024). An in silico approach to elucidate the pathways leading to primary osteoporosis: age-related vs. postmenopausal. Biomechanics and Modeling in Mechanobiology. [More Information]
• Scheller, E., Mcdonald, M., Andersen, T., Sumner, D., Noda, M., Erben, R., Boyce, B., Compston, J., Dempster, D., Takahashi, H., et al (2024). Celebrating 50-years: the history and future of the International Society of Bone Morphometry. JBMR Plus, 8(7). [More Information]
• El-Masri, B., Hansen, L., Kim, A., Taylor, V., Massarotti, C., Mcdonald, M., You, X., Charles, J., Delaisse, J., Andersen, T., et al (2024). Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect. Bone Research, 12(1), 62. [More Information]
• Park-Min, K., Mun, S., Bockman, R., Mcdonald, M. (2024). New Horizons: Translational Aspects of Osteomorphs. Journal of Clinical Endocrinology and Metabolism, 109(5), e1373-e1378. [More Information]
• Kim, A., Chai, R., Croucher, P., Center, J., Girgis, C., Mcdonald, M., Taylor, V., Castro-Martinez, A., Dhakal, S., Zamerli, A., et al (2024). Temporal patterns of osteoclast formation and activity following withdrawal of RANKL inhibition. Journal of Bone and Mineral Research, 39(4), 484-497. [More Information]
• Cung, M., Greenblatt, M., Sosa, B., Yang, H., Mcdonald, M., Matthews, B., Vlug, A., Imel, E., Wein, M., Stein, E. (2024). The performance of artificial intelligence chatbot large language models to address skeletal biology and bone health queries. Journal of Bone and Mineral Research, 39(2), 106-115. [More Information]

2023

• Diamond, T., Bryant, C., Quinn, R., Mohanty, S., Bonar, F., Baldock, P., Mcdonald, M. (2023). Increased Bone Formation and Accelerated Bone Mass Accrual in a Man Presenting with Diffuse Osteosclerosis/High Bone Mass Phenotype and Adenocarcinoma of Unknown Primary. JBMR Plus, 7(8). [More Information]
• Mulholland, B., Hofstee, P., Millar, E., Bliuc, D., OToole, S., Forwood, M., Mcdonald, M. (2023). MCP-1 expression in breast cancer and its association with distant relapse. Cancer Medicine, 12(15), 16221-16230. [More Information]
• Bhattacharyya, N., Sergio, C., Timpson, P., Lee, W., Croucher, P., Giang Phan, T., Kyaw, W., Mcdonald, M., Dhenni, R., Grootveld, A., et al (2023). Minimally invasive longitudinal intravital imaging of cellular dynamics in intact long bone. Nature Protocols, 18(12), 3856-3880. [More Information]
• Koo, S., Lee, E., Xiong, H., Yun, D., Mcdonald, M., Park, S., Kim, J. (2023). Real-Time Live Imaging of Osteoclast Activation via Cathepsin K Activity in Bone Diseases. Angewandte Chemie - International Edition. [More Information]

2022

• Kim, A., Girgis, C., McDonald, M. (2022). Osteoclast Recycling and the Rebound Phenomenon Following Denosumab Discontinuation. Current Osteoporosis Reports, 20(6), 505-515. [More Information]
• Dao, A., Mcdonald, M., Savage, P., Little, D., Schindeler, A. (2022). Preventing osteolytic lesions and osteomyelitis in multiple myeloma. Journal of Bone Oncology, 37. [More Information]
• Chai, R., Mcdonald, M. (2022). Visualisation of tumour cells in bone in vivo at single-cell resolution. Bone, 158, 116113. [More Information]

2021

• Fairfield, H., Dudakovic, A., Khatib, C., Farrell, M., Costa, S., Falank, C., Hinge, M., Murphy, C., Demambro, V., Pettitt, J., Mcdonald, M., et al (2021). Myeloma-Modified Adipocytes Exhibit Metabolic Dysfunction and a Senescence-Associated Secretory Phenotype. Cancer Research, 81(3), 634-647. [More Information]
• McDonald, M., Kim, A., Mulholland, B., Rauner, M. (2021). New Insights Into Osteoclast Biology. JBMR Plus, 5(9). [More Information]
• McDonald, M., Khoo, W., Ng, P., Xiao, Y., Zamerli, J., Thatcher, P., Kyaw, W., Pathmanandavel, K., Grootveld, A., Moran, I., et al (2021). Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption. Cell, 184(5), 1330-1.35E+16. [More Information]
• Youlten, S., Kemp, J., Logan, J., Ghirardello, E., Sergio, C., Dack, M., Guilfoyle, S., Leitch, V., Butterfield, N., Komla-Ebri, D., Mcdonald, M., et al (2021). Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal Disease. Nature Communications, 12(1), 2444. [More Information]
• Kim, A., McDonald, M., Girgis, C. (2021). The relationship between sleep and bone: Strange bedfellows? Current Opinion in Endocrine and Metabolic Research, 18, 236-242. [More Information]

2020

• Summers, M., McDonald, M., Croucher, P. (2020). Cancer Cell Dormancy in Metastasis. Cold Spring Harbor Perspectives in Medicine, 10(4), a037556. [More Information]
• John-Rickert, K., Wolfel, E., Jobke, B., Riedel, C., Hellmich, M., Werner, M., McDonald, M., Busse, B. (2020). Elevated Bone Hardness Under Denosumab Treatment, With Persisting Lower Osteocyte Viability During Discontinuation. Frontiers in Endocrinology, 11(250), 1-13. [More Information]
• Morse, A., Ko, F., McDonald, M., Lee, L., Schindeler, A., Van Der Meulen, M., Little, D. (2020). Increased anabolic bone response in Dkk1 KO mice following tibial compressive loading. Bone, 131, 115054. [More Information]
• Simic, M., McDonald, M. (2020). Myeloma Bone Disease. In Not known (Eds.), Encyclopedia of Bone Biology, (pp. 342-354). TBC. [More Information]
• Morse, A., McDonald, M., Mikulec, K., Schindeler, A., Munns, C., Little, D. (2020). Pretreatment with Pamidronate Decreases Bone Formation but Increases Callus Bone Volume in a Rat Closed Fracture Model. Calcified Tissue International, 106(2), 172-179. [More Information]
• Owen, K., Gearing, L., Zanker, D., Brockwell, N., Khoo, W., Roden, D., Cmero, M., Mangiola, S., Hong, M., Spurling, A., Hayes, V., et al (2020). Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone. EMBO Reports, 21(6), 1-24. [More Information]

2019

• Khoo, W., Ledergor, G., Weiner, A., Roden, D., Terry, R., McDonald, M., Chai, R., De Veirman, K., Owen, K., Opperman, K., et al (2019). A niche-dependent myeloid transcriptome signature defines dormant myeloma cells. Blood, 134(1), 30-43. [More Information]
• Horas, K., Zheng, Y., Fong-Yee, C., Macfarlane, E., Manibo, J., Chen, Y., Qiao, J., Gao, M., Haydar, N., McDonald, M., Zhou, H., Seibel, M., et al (2019). Loss of the Vitamin D Receptor in Human Breast Cancer Cells Promotes Epithelial to Mesenchymal Cell Transition and Skeletal Colonization. Journal of Bone and Mineral Research, 34(9), 1721-1732. [More Information]
• Byrne, N., Summers, M., Mcdonald, M. (2019). Tumor Cell Dormancy and Reactivation in Bone: Skeletal Biology and Therapeutic Opportunities. JBMR Plus, 3(3), e10125. [More Information]

2018

• Morse, A., Cheng, T., Schindeler, A., McDonald, M., Mohanty, S., Kneissel, M., Kramer, I., Little, D. (2018). Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume. Calcified Tissue International, 103(3), 298-310. [More Information]
• McDonald, M., Morse, A., Schindeler, A., Mikulec, K., Peacock, L., Cheng, T., Bobyn, J., Lee, L., Baldock, P., Croucher, P., Tam, P., Little, D. (2018). Homozygous Dkk1 Knockout Mice Exhibit High Bone Mass Phenotype Due to Increased Bone Formation. Calcified Tissue International, 102(1), 105-116. [More Information]
• Morse, A., Schindeler, A., McDonald, M., Kneissel, M., Kramer, I., Little, D. (2018). Sclerostin antibody augments the anabolic bone formation response in a mouse model of mechanical tibial loading. Journal of Bone and Mineral Research, 33(3), 486-498. [More Information]
• McDonald, M., Morse, A., Birke, O., Yu, N., Mikulec, K., Peacock, L., Schindeler, A., Liu, M., Ke, H., Little, D. (2018). Sclerostin antibody enhances bone formation in a rat model of distraction osteogenesis. Journal of Orthopaedic Research, 36(4), 1106-1113. [More Information]
• Fairfield, H., Falank, C., Harris, E., Demambro, V., McDonald, M., Pettitt, J., Mohanty, S., Croucher, P., Kramer, I., Kneissel, M., et al (2018). The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis. Journal of Cellular Physiology, 233(2), 1156-1167. [More Information]
• Haydar, N., Mcdonald, M. (2018). Tumor Cell Dormancy—a Hallmark of Metastatic Growth and Disease Recurrence in Bone. Current Molecular Biology Reports, 4, 50-58. [More Information]

2017

• McDonald, M., Fairfield, H., Falank, C., Reagan, M. (2017). Adipose, Bone, and Myeloma: Contributions from the Microenvironment. Calcified Tissue International, 100(5), 433-448. [More Information]
• McDonald, M., Reagan, M., Youlten, S., Mohanty, S., Seckinger, A., Terry, R., Pettitt, J., Simic, M., Cheng, T., Morse, A., Little, D., et al (2017). Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma. Blood, 129(26), 3452-3464. [More Information]
• Chai, R., McDonald, M., Terry, R., Kovacic, N., Down, J., Pettitt, J., Mohanty, S., Shah, S., Haffari, G., Xu, J., et al (2017). Melphalan modifies the bone microenvironment by enhancing osteoclast formation. Oncotarget, 8(40), 68047-68058. [More Information]
• Morse, A., McDonald, M., Schindeler, A., Peacock, L., Mikulec, K., Cheng, T., Liu, M., Ke, H., Little, D. (2017). Sclerostin Antibody Increases Callus Size and Strength but does not Improve Fracture Union in a Challenged Open Rat Fracture Model. Calcified Tissue International, 101(2), 217-228. [More Information]
• Mcdonald, M., Delgado-Calle, J. (2017). Sclerostin: an emerging target for the treatment of cancer-induced bone disease. Current Osteoporosis Reports, 15(6), 532-541. [More Information]

2016

• Croucher, P., McDonald, M., Martin, T. (2016). Bone metastasis: The importance of the neighbourhood. Nature Reviews Cancer, 16(6), 373-386. [More Information]

2015

• Morse, A., Yu, N., Peacock, L., Mikulec, K., Kramer, I., Kneissel, M., McDonald, M., Little, D. (2015). Endochondral fracture healing with external fixation in the Sost knockout mouse results in earlier fibrocartilage callus removal and increased bone volume fraction and strength. Bone, 71, 155-163. [More Information]
• Lawson, M., McDonald, M., Kovacic, N., Khoo, W., Terry, R., Down, J., Kaplan, W., Paton-Hough, J., Fellows, C., Pettitt, J., et al (2015). Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche. Nature Communications, 6. [More Information]

2014

• Morse, A., McDonald, M., Kelly, N., Melville, K., Schindeler, A., Kramer, I., Kneissel, M., Van Der Meulen, M., Little, D. (2014). Mechanical Load Increases in Bone Formation Via a Sclerostin-Independent Pathway. Journal of Bone and Mineral Research, 29(11), 2456-2467. [More Information]
• El-Hoss, J., Kolind, M., Jackson, M., Deo, N., Mikulec, K., McDonald, M., Little, C., Little, D., Schindeler, A. (2014). Modulation of endochondral ossification by MEK inhibitors PD0325901 and AZD6244 (Selumetinib). Bone, 59, 151-161. [More Information]
• Quain, A., Malik, R., Howlett, R., McDonald, M., Culvenor, J., Pool, R., Allan, G. (2014). Polyostotic hyperostosis in a domestic shorthair cat. Journal of Feline Medicine and Surgery, 16(5), 432-440. [More Information]
• Kovacic, N., Croucher, P., McDonald, M. (2014). Signaling between tumor cells and the host bone marrow microenvironment. Calcified Tissue International, 94(1), 125-139. [More Information]

2013

• Bosemark, P., Isaksson, H., Mcdonald, M., Little, D., Tagil, M. (2013). Augmentation of autologous bone graft by a combination of bone morphogenic protein and bisphosphonate increased both callus volume and strength. Acta Orthopaedica, 84(1), 106-111. [More Information]
• McDonald, M., Morse, A., Mikulec, K., Peacock, L., Baldock, P., Kostenuik, P., Little, D. (2013). Matrix Metalloproteinase - Driven Endochondral Fracture Union Proceeds Independently of Osteoclast Activity. Journal of Bone and Mineral Research, 28(7), 1550-1560. [More Information]
• Sousa, D., McDonald, M., Mikulec, K., Peacock, L., Herzog, H., Lamghari, M., Little, D., Baldock, P. (2013). Neuropeptide Y modulates fracture healing through Y1 receptor signaling. Journal of Orthopaedic Research, 31(10), 1570-1578. [More Information]

2012

• McDonald, M., Morse, A., Mikulec, K., Peacock, L., Yu, N., Baldock, P., Birke, O., Liu, M., Ke, H., Little, D. (2012). Inhibition of Sclerostin by Systemic Treatment with Sclerostin Antibody Enhances Healing of Proximal Tibial Defects in Ovariectomized Rats. Journal of Orthopaedic Research, 30(10), 1541-1548. [More Information]

2011

• McDonald, M., Morse, A., Peacock, L., Mikulec, K., Schindeler, A., Little, D. (2011). Characterization of the Bone Phenotype and Fracture Repair in Osteopetrotic Incisors Absent Rats. Journal of Orthopaedic Research, 29(5), 726-733. [More Information]
• Yang, N., Schindeler, A., McDonald, M., Seto, J., Houweling, P., Lek, M., Hogarth, M., Morse, A., Raftery, J., Balasuriya, D., Berman, Y., Quinlan (nee Edwards), K., Little, D., North, K., et al (2011). α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse. Bone, 49(4), 790-798. [More Information]

2010

• Tagil, M., McDonald, M., Morse, A., Peacock, L., Mikulec, K., Maddock (nee Amanat), N., Godfrey, C., Little, D. (2010). Intermittent PTH(1-34) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures. Bone, 46(3), 852-859. [More Information]
• Schindeler, A., Morse, A., Peacock, L., Mikulec, K., Yu, N., Liu, R., Kijumnuayporn, S., McDonald, M., Baldock, P., Ruys, A., Little, D. (2010). Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics. BMC Musculoskeletal Disorders, 11(105), 105-1-105-9. [More Information]
• Zreiqat, H., Ramaswamy, Y., Wu, C., Paschalidis, A., Lu, Z., James, B., Birke, O., Mcdonald, M., Little, D., Dunstan, C. (2010). The incorporation of strontium and zinc into a calcium-silicon ceramic for bone tissue engineering. Biomaterials, 31(12), 3175-3184. [More Information]

2008

• Yu, N., Ruys, A., Zenios, M., Godfrey, C., McDonald, M., Kiely, P., Mikulec, K., Little, D., Schindeler, A. (2008). Bisphosphonate-Laden Acrylic Bone Cement: Mechanical Properties, Elution Performance, and In Vivo Activity. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 87B(2), 482-491. [More Information]
• McDonald, M., Dulai, S., Godfrey, C., Maddock (nee Amanat), N., Sztynda, T., Little, D. (2008). Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling. Bone, 43(4), 653-662. [More Information]
• Schindeler, A., McDonald, M., Little, D., Bokka, P. (2008). Bone remodeling during fracture repair: The cellular picture. Seminars in Cell and Developmental Biology, 19(5), 459-466. [More Information]
• Schindeler, A., Ramachandran, M., Godfrey, C., Morse, A., McDonald, M., Mikulec, K., Little, D. (2008). Modeling Bone Morphogenetic Protein and Bisphosphonate Combination Therapy in Wild-Type and Nf1 Haploinsufficient Mice. Journal of Orthopaedic Research, 26(1), 65-74. [More Information]
• Schindeler, A., Morse, A., Harry, L., Godfrey, C., Mikulec, K., McDonald, M., Gasser, J., Little, D. (2008). Models of Tibial Fracture Healing in Normal and Nf1-Deficient Mice. Journal of Orthopaedic Research, 26(8), 1053-1060. [More Information]
• McDonald, M., Tagil, M., Morse, A., Godfrey, C., Maddock (nee Amanat), N., Little, D. (2008). PTH treatment increases fracture callus size and strength more effectively in closed than open fractures. Bone, 42(Supplement 1), S78-S79. [More Information]
• Chang, A., Hook, J., Lemckert, F., McDonald, M., Nguyen, M., Hardeman, E., Little, D., Gunning, P., Reddel, R. (2008). The murine stanniocalcin 2 gene is a negative regulator of postnatal growth. Endocrinology, 149(5), 2403-2410. [More Information]

2007

• Baldock, P., Allison, S., Lundberg, P., Lee, N., Slack, K., Lin, E., Enriquez, R., Mcdonald, M., Zhang, L., During, M., Little, D., et al (2007). Novel role of y1 receptors in the coordinated regulation of bone and energy homeostasis. Journal of Biological Chemistry, 282(26), 19092-19102. [More Information]
• Maddock (nee Amanat), N., McDonald, M., Godfrey, C., Bilston, L., Little, D. (2007). Optimal timing of a single dose of zoledronic acid to increase strength in rat fracture repair. Journal of Bone and Mineral Research, 22(6), 867-876. [More Information]

2006

• McDonald, M., Dulai, S., Godfrey, C., Sztynda, T., Little, D. (2006). Endochondral repair and development proceed normally during zoledronic acid treatment.
• Baldock, P., Allison, S., McDonald, M., Sainsbury, A., Enriquez, R., Little, D., Eisman, J., Gardiner, E., Herzog, H. (2006). Hypothalamic regulation of cortical bone mass: opposing activity of Y2 receptor and leptin pathways. Journal of Bone and Mineral Research, 21(10), 1600-1607. [More Information]
• Maddock (nee Amanat), N., McDonald, M., Godfrey, C., Bilston, L., Little, D. (2006). Optimal timing of bolus intravenous zoledronic acid in a rat fracture model. Bone, 38, S43-S43.
• McDonald, M., Dulai, S., Godfrey, C., Sztynda, T., Little, D. (2006). Single dose zoledronic acid treatment is superior to continuous treatment in enhancing hard callus formation and strength without delayed remodelling. [More Information]
• Jackson, R., McDonald, M., Nurcombe, V., Little, D., Cool, S. (2006). The use of heparan sulfate to augment fracture repair in a rat fracture model. Journal of Orthopaedic Research, 24(4), 636-644. [More Information]

2005

• Little, D., Bransford, R., McDonald, M., Godfrey, C., Maddock (nee Amanat), N. (2005). Manipulation of the anabolic and catabolic responses in a critical defect model with OP-1 and zoledronic acid. 2nd Joint Meeting of the European Calcified Tissue Society and the International Bone and Mineral Society, New York: Elsevier Science.
• Little, D., Mcdonald, M., Bransford, R., Godfrey, C., Maddock (nee Amanat), N. (2005). Manipulation of the anabolic and catabolic responses with OP-1 and zoledronic acid in a rat critical defect model. Journal of Bone and Mineral Research, 20(11), 2044-52. [More Information]
• Little, D., McDonald, M., Sharpe, I., Peat, R., Williams, P., McEvoy, A. (2005). Zoledronic acid improves femoral head sphericity in a rat model of perthes disease. Journal of Orthopaedic Research, 23(4), 862-868. [More Information]
• Mcdonald, M., Dulai, S., Godfrey, C., Hamilton, B., Little, D. (2005). Zoledronic acid treatment enhances hard callus formation without delaying endochondral repair in a rat fracture model. Bone, 36(point P377-Mo), S305-S305.