2024

• Eldehna, W., Elsayed, Z., Ammara, A., El Hassab, M., Almahli, H., Fares, M., Nocentini, A., Supuran, C., Abou-Seri, S. (2024). Discovery of new sulfonamide-tethered 2-aryl-4-anilinoquinazolines as the first-in-class dual carbonic anhydrase and EGFR inhibitors. International Journal of Biological Macromolecules, 279(Pt 2), 135010. [More Information]
• Ryder, W., Wu, E., Chen, L., Metwaly, M., McNaughton, D., Tran, K., Yu, C., Gale, P. (2024). Furazan bis-ureas: a heterocyclic scaffold for anion binding and transport. Organic Chemistry Frontiers, 11(5), 1290-1298. [More Information]
• Wang, P., Metwaly, M., Eladwy, R., Bhuyan, D., Wu, X., Lewis, W., Loeb, S., Macreadie, L., Gale, P. (2024). Platinum-based metal complexes as chloride transporters that trigger apoptosis. Chemical Science. [More Information]
• Gilchrist, A., McNaughton, D., Metwaly, M., Wu, X., Hawkins, B., Butler, S., Hibbs, D., Gale, P. (2024). Tetralactam-based anion transporters. Chem. [More Information]
• Eladwy, R., Alsherbiny, M., Chang, D., Metwaly, M., Li, C., Bhuyan, D. (2024). The postbiotic sodium butyrate synergizes the antiproliferative effects of dexamethasone against the AGS gastric adenocarcinoma cells. Frontiers in Nutrition, 11. [More Information]

2023

• Metwaly, M., Wu, X., McNaughton, D., Gilchrist, A., Lewis, W., Keller, P., Arias-Betancur, A., Fontova, P., Pérez-Tomás, R., Gale, P. (2023). A potent fluorescent transmembrane HCl transporter perturbs cellular pH and promotes cancer cell death. Organic and Biomolecular Chemistry, 21(12), 2509-2515. [More Information]
• Eldehna, W., Mohammed, E., Al-Ansary, G., Berrino, E., Elbadawi, M., Ibrahim, T., Jaballah, M., Al-Rashood, S., Binjubair, F., Celik, M., Metwaly, M., et al (2023). Design and synthesis of 6-arylpyridine-tethered sulfonamides as novel selective inhibitors of carbonic anhydrase IX with promising antitumor features toward the human colorectal cancer. European Journal of Medicinal Chemistry, 258. [More Information]
• McNaughton, D., Ryder, W., Gilchrist, A., Wang, P., Metwaly, M., Wu, X., Gale, P. (2023). New insights and discoveries in anion receptor chemistry. Chem, 9(11), 3045-3112. [More Information]

2022

• Said, M., Abdelrahman, M., Abourehab, M., Metwaly, M., Eldehna, W. (2022). A patent review of anticancer CDK2 inhibitors (2017–present). Expert Opinion on Therapeutic Patents, 32(8), 885-898. [More Information]
• Elbadawi, M., Eldehna, W., Nocentini, A., Somaa, W., Al-Rashood, S., Elkaeed, E., El Hassab, M., Abdel-Aziz, H., Supuran, C., Metwaly, M. (2022). Development of 4-((3-oxo-3-phenylpropyl)amino)benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors. European Journal of Medicinal Chemistry, 238. [More Information]
• Eldehna, W., El Hassab, M., Abdelshafi, N., Al-Zahraa Sayed, F., Metwaly, M., Al-Rashood, S., Elsayed, Z., Abdel-Aziz, M., Elkaeed, E., Elsabahy, M., et al (2022). Development of potent nanosized isatin-isonicotinohydrazide hybrid for management of Mycobacterium tuberculosis. International Journal of Pharmaceutics, 612, 121369. [More Information]
• Howe, E., Chang, V., Wu, X., Metwaly, M., Lewis, W., Macreadie, L., Gale, P. (2022). Halide-selective, proton-coupled anion transport by phenylthiosemicarbazones. Biochimica et Biophysica Acta - Biomembranes, 1864 (2), 183828. [More Information]
• Macreadie, L., Gilchrist, A., McNaughton, D., Ryder, W., Metwaly, M., Gale, P. (2022). Progress in Anion Receptor Chemistry. Chem, 8(1), 46-118. [More Information]
• Metwaly, M., Canfield, P., Alsherbiny, M., Lewis, W., Willis, A., Li, C., Neyts, J., Jochmans, D., Gale, P., Keller, P. (2022). Synthesis, X-ray crystallographic analysis, DFT studies and biological evaluation of triazolopyrimidines and 2-anilinopyrimidines. Journal of Molecular Structure, 1252, 132092. [More Information]

2021

• Williams, G., Haynes, C., Metwaly, M., Caltagirone, C., Hiscock, J., Gale, P. (2021). Advances in applied supramolecular technologies. Chemical Society Reviews, 50(4), 2737-2763. [More Information]
• McNaughton, D., Metwaly, M., Picci, G., Gale, P., Caltagirone, C. (2021). Advances in fluorescent and colorimetric sensors for anionic species. Coordination Chemistry Reviews, 427, 213573. [More Information]
• El Hassab, M., Metwaly, M., Amin, M., Al-Rashood, S., Alharbi, A., Eskandrani, R., Alkahtani, H., Eldehna, W. (2021). Toward the identification of potential α-ketoamide covalent inhibitors for sars-cov-2 main protease: Fragment-based drug design and mm-pbsa calculations. Processes, 9(6), 1004. [More Information]

2020

• Metwaly, M., Eldehna, W., Bua, S., Lanzi, C., Lucarini, L., Masini, E., Peat, T., Abdel-Aziz, H., Nocentini, A., Keller, P., et al (2020). Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action. Journal of Medicinal Chemistry, 63(6), 3317-3326. [More Information]
• Metwaly, M., McCosker, P., Alsherbiny, M., Willis, A., Clark, T., Neyts, J., Jochmans, D., Keller, P. (2020). Regioselective convergent synthesis of 2-arylidene thiazolo[3,2-: A] pyrimidines as potential anti-chikungunya agents. RSC Advances, 10(9), 5191-5195. [More Information]
• Metwaly, M., Wu, X., Ramesh, D., Lewis, W., Keller, P., Howe, E., Pérez-Tomás, R., Gale, P. (2020). Stimuli-Responsive Cycloaurated “OFF-ON” Switchable Anion Transporters. Angewandte Chemie - International Edition, 59(40), 17614-17621. [More Information]

2019

• Alsherbiny, M., Abd-Elsalam, W., El badawy, S., Taher, E., Fares, M., Torres, A., Chang, D., Li, C. (2019). Ameliorative and protective effects of ginger and its main constituents against natural, chemical and radiation-induced toxicities: A comprehensive review. Food and Chemical Toxicology, 123, 72-97. [More Information]
• Eldehna, W., Almahli, H., Ibrahim, T., Fares, M., Al-Warhi, T., Boeckler, F., Bekhit, A., Abdel-Aziz, H. (2019). Synthesis, in vitro biological evaluation and in silico studies of certain arylnicotinic acids conjugated with aryl (thio)semicarbazides as a novel class of anti-leishmanial agents. European Journal of Medicinal Chemistry, 179, 335-346. [More Information]

2018

• Fares, M., Abd El Hadi, S., Eladwy, R., Shoun, A., Abdel-Aziz, M., Eldehna, W., Abdel-Aziz, H., Keller, P. (2018). An improved synthesis of pyrido[2,3-d]pyrimidin-4(1H)-ones and their antimicrobial activity. Organic and Biomolecular Chemistry, 16(18), 3389-3395. [More Information]
• Eladwy, R., Mantawy, E., El-Bakly, W., Fares, M., Ramadan, L., Azab, S. (2018). Mechanistic insights to the cardioprotective effect of blueberry nutraceutical extract in isoprenaline-induced cardiac hypertrophy. Phytomedicine, 51, 84-93. [More Information]
• El-Naggar, M., Eldehna, W., Almahli, H., Elgez, A., Fares, M., Elaasser, M., Abdel-Aziz, H. (2018). Novel Thiazolidinone/Thiazolo[3,2- a]Benzimidazolone-Isatin Conjugates as Apoptotic Anti-proliferative Agents Towards Breast Cancer: One-Pot Synthesis and In Vitro Biological Evaluation. Molecules, 23(6), 1420. [More Information]

2017

• Eldehna, W., Abo-Ashour, M., Nocentini, A., Gratteri, P., Eissa, I., Fares, M., Ismael, O., Ghabbour, H., Elaasser, M., Abdel-Aziz, H., et al (2017). Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies. European Journal of Medicinal Chemistry, 139, 250-262. [More Information]
• Fares, M., Eladwy, R., Nocentini, A., Abd El Hadi, S., Ghabbour, H., Abdel-Megeed, A., Eldehna, W., Abdel-Aziz, H., Supuran, C. (2017). Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects. Bioorganic and Medicinal Chemistry, 25(7), 2210-2217. [More Information]

2016

• Eldehna, W., Fares, M., Ceruso, M., Ghabbour, H., Abou-Seri, S., Abdel-Aziz, H., Abou El Ella, D., Supuran, C. (2016). Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII. European Journal of Medicinal Chemistry, 110, 259-266. [More Information]
• Eldehna, W., Fares, M., Ibrahim, H., Alsherbiny, M., Aly, M., Ghabbour, H., Abdel-Aziz, H. (2016). Synthesis and cytotoxic activity of biphenylurea derivatives containing indolin-2-one moieties. Molecules, 21(6), 762. [More Information]
• Fares, M., Said, M., Alsherbiny, M., Eladwy, R., Almahli, H., Abdel-Aziz, M., Ghabbour, H., Eldehna, W., Abdel-Aziz, H. (2016). Synthesis, Biological evaluation and molecular docking of certain sulfones as potential nonazole antifungal agents. Molecules, 21(1), E114. [More Information]

2015

• Eldehna, W., Fares, M., Abdel-Aziz, M., Abdel-Aziz, H. (2015). Design, synthesis and antitubercular activity of certain nicotinic Acid hydrazides. Molecules, 20(5), 8800-8815. [More Information]
• Fares, M., Eldehna, W., Abou-Seri, S., Abdel-Aziz, H., Aly, M., Tolba, M. (2015). Design, Synthesis and In Vitro Antiproliferative Activity of Novel Isatin-Quinazoline Hybrids. Archiv Der Pharmazie, 348(2), 144-154. [More Information]
• Eldehna, W., Fares, M., Ibrahim, H., Aly, M., Zada, S., Mamdouh, A., Abou-Seri, S., Abdel-Aziz, H., Abou El Ella, D. (2015). Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking. European Journal of Medicinal Chemistry, 100, 89-97. [More Information]
• Abdel-Aziz, H., Eldehna, W., Fares, M., Al-Rashood, S., Al-Rashood, K., Abdel-Aziz, M., Soliman, D. (2015). Synthesis, biological evaluation and 2D-QSAR study of halophenyl bis-hydrazones as antimicrobial and antitubercular agents. International Journal of Molecular Sciences, 16(4), 8719-8743. [More Information]
• Abdel-Aziz, H., Eldehna, W., Fares, M., Elsaman, T., Abdel-Aziz, M., Soliman, D. (2015). Synthesis, in Vitro and in Silico Studies of Some Novel 5-Nitrofuran-2-yl Hydrazones as Antimicrobial and Antitubercular Agents. Biological and Pharmaceutical Bulletin, 38(10), 1617-1630. [More Information]

2014

• Fares, M., Abou-Seri, S., Abdel-Aziz, H., Abbas, S., Youssef, M., Eladwy, R. (2014). Synthesis and antitumor activity of pyrido [2,3-d]pyrimidine and pyrido[2,3-d] [1,2,4]triazolo[4,3-a]pyrimidine derivatives that induce apoptosis through G1 cell-cycle arrest. European Journal of Medicinal Chemistry, 83, 155-166. [More Information]

2013

• Elsaman, T., Fares, M., Abdel-Aziz, H., Attia, M., Ghabbour, H., Dawood, K. (2013). A Facile Synthesis of Pyrido[,:3,4]pyrazolo[1,5-a]pyrimidine and Pyrido[,:3,4]pyrazolo[5,1-c][1,2,4]triazine Bearing a Thiophene Moiety. Journal of Chemistry, 2013 (463515), 1-7. [More Information]