Associate Professor Paul Healey
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Associate Professor Paul Healey

B(Med)Sc (Cell Biology), MBBS(Hons), MMed (Clin. Epidemiology), PhD, FRANZCO
Clinical Associate Professor
Clinical Ophthalmology &
Eye Health, Westmead Clinical School
Phone
02 9247 9972
Fax
02 9232 3086
Associate Professor Paul Healey

Selected publications

Publications

Books

  • Healey, P., Thomas, R. (2010). Fast Facts: Glaucoma. United Kingdom: Health Press Limited.

Edited Books

  • Weinreb, R., Healey, P., Topouzis, F. (2008). Glaucoma Screening. Amsterdam, The Netherlands: Kugler Publications.

Book Chapters

  • Healey, P. (2009). Screening for Glaucoma. In T.M. Shaarawy, M.B. Sherwood, R.A. Hitchings, J.G. Crowston (Eds.), Glaucoma, (pp. 15-23). United Kingdom: Elsevier.
  • Irwig, L., Healey, P., D'Assuncao, J., Macaskill, P. (2008). Monitoring intraocular pressure in glaucoma. In P Glasziou, L Irwig and J K Aronson (Eds.), Evidence-based Medical Monitoring:From Principles to Practice, (pp. 325-334). Oxford: Blackwell Publishers. [More Information]
  • Healey, P., Trope, G. (2005). The Failing Bleb: Diagnosis and management. In Trope G (Eds.), Glaucoma Surgery, (pp. 159-178). United States: Taylor & Francis.

Journals

  • Al-Timimi, Z., Huang-Lung, J., Keay, L., Healey, P., Yang, E., Dunn, H. (2023). A Systematic Review of Glaucoma Diagnosis in Prevalence Studies and Quality of Reporting. Journal of Glaucoma, 32(10), 874-884. [More Information]
  • Marshall, H., Berry, E., Torres, S., Mullany, S., Schmidt, J., Thomson, D., Nguyen, T., Knight, L., Hollitt, G., Qassim, A., Healey, P., et al (2023). Association Between Body Mass Index and Primary Open Angle Glaucoma in Three Cohorts. American Journal of Ophthalmology, 245, 126-133. [More Information]
  • Siggs, O., Qassim, A., Han, X., Marshall, H., Mullany, S., He, W., Souzeau, E., Galanopoulos, A., Agar, A., Landers, J., Healey, P., et al (2023). Association of High Polygenic Risk with Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma. JAMA Ophthalmology, 141(1), 73-77. [More Information]

2023

  • Al-Timimi, Z., Huang-Lung, J., Keay, L., Healey, P., Yang, E., Dunn, H. (2023). A Systematic Review of Glaucoma Diagnosis in Prevalence Studies and Quality of Reporting. Journal of Glaucoma, 32(10), 874-884. [More Information]
  • Marshall, H., Berry, E., Torres, S., Mullany, S., Schmidt, J., Thomson, D., Nguyen, T., Knight, L., Hollitt, G., Qassim, A., Healey, P., et al (2023). Association Between Body Mass Index and Primary Open Angle Glaucoma in Three Cohorts. American Journal of Ophthalmology, 245, 126-133. [More Information]
  • Siggs, O., Qassim, A., Han, X., Marshall, H., Mullany, S., He, W., Souzeau, E., Galanopoulos, A., Agar, A., Landers, J., Healey, P., et al (2023). Association of High Polygenic Risk with Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma. JAMA Ophthalmology, 141(1), 73-77. [More Information]

2022

  • Healey, P., Tilden, D., Jackson, D., Aghajanian, L. (2022). A Cost-Utility Analysis of Trabecular Bypass Devices Versus Usual Care for Patients With Open-Angle Glaucoma. PharmacoEconomics - Open, 6(3), 355-365. [More Information]
  • Dunn, H., Marks, S., Teo, K., Dunn, S., Healey, P., White, A. (2022). Applications of electronic devices based on smartphones in ophthalmic diagnosis and treatment activities: Response. Clinical and Experimental Ophthalmology, 50(3), 351-352. [More Information]
  • Lin, F., Chen, S., Song, Y., Li, F., Wang, W., Zhao, Z., Gao, X., Wang, P., Jin, L., Liu, Y., Healey, P., et al (2022). Classification of Visual Field Abnormalities in Highly Myopic Eyes without Pathologic Change. Ophthalmology, 129(7), 803-812. [More Information]

2021

  • Qassim, A., Mullany, S., Awadalla, M., Hassall, M., Nguyen, T., Marshall, H., Kolovos, A., Schulz, A., Han, X., Gharahkhani, P., Healey, P., et al (2021). A polygenic risk score predicts intraocular pressure readings outside office hours and early morning spikes as measured by home tonometry. Ophthalmology Glaucoma, 4(4), 411-420. [More Information]
  • Marshall, H., Mullany, S., Qassim, A., Siggs, O., Hassall, M., Ridge, B., Nguyen, T., Awadalla, M., Andrew, N., Healey, P., et al (2021). Cardiovascular Disease Predicts Structural and Functional Progression in Early Glaucoma. Ophthalmology, 128(1), 58-69. [More Information]
  • Qassim, A., Mullany, S., Abedi, F., Marshall, H., Hassall, M., Kolovos, A., Knight, L., Nguyen, T., Awadalla, M., Chappell, A., Healey, P., et al (2021). Corneal Stiffness Parameters Are Predictive of Structural and Functional Progression in Glaucoma Suspect Eyes. Ophthalmology, 128(7), 993-1004. [More Information]

2020

  • Qassim, A., Souzeau, E., Siggs, O., Hassall, M., Han, X., Griffiths, H., Frost, N., Vallabh, N., Kirwan, J., Menon, G., Healey, P., et al (2020). An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity. Ophthalmology, 127(7), 901-907. [More Information]
  • Qassim, A., Walland, M., Landers, J., Awadalla, M., Nguyen, T., Loh, J., Schulz, A., Ridge, B., Galanopoulos, A., Agar, A., Healey, P., et al (2020). Effect of phacoemulsification cataract surgery on intraocular pressure in early glaucoma: A prospective multi-site study. Clinical and Experimental Ophthalmology, 48(4), 442-449. [More Information]
  • Craig, J., Han, X., Qassim, A., Hassall, M., Bailey, J., Kinzy, T., Khawaja, A., An, J., Marshall, H., Gharahkhani, P., Healey, P., White, A., Goldberg, I., Mitchell, P., et al (2020). Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Nature Genetics, 52(2), 160-166. [More Information]

2019

  • Marshall, H., Andrew, N., Hassall, M., Qassim, A., Souzeau, E., Ridge, B., Nguyen, T., Fitzgerald, J., Awadalla, M., Burdon, K., Healey, P., et al (2019). Macular Ganglion Cell–Inner Plexiform Layer Loss Precedes Peripapillary Retinal Nerve Fiber Layer Loss in Glaucoma with Lower Intraocular Pressure. Ophthalmology, 126(8), 1119-1130. [More Information]
  • Han, X., Souzeau, E., Ong, J., An, J., Siggs, O., Burdon, K., Best, S., Goldberg, I., Healey, P., Graham, S., White, A., et al (2019). Myocilin Gene Gln368Ter Variant Penetrance and Association With Glaucoma in Population-Based and Registry-Based Studies. JAMA Ophthalmology, 137(1), 28-35. [More Information]

2018

  • Gharahkhani, P., Burdon, K., Cooke Bailey, J., Hewitt, A., Law, M., Pasquale, L., Kang, J., Haines, J., Souzeau, E., Zhou, T., Goldberg, I., White, A., Healey, P., Grigg, J., Lawlor, M., Mitchell, P., et al (2018). Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma. Scientific Reports, 8(1), 1-12. [More Information]
  • Burdon, K., Awadalla, M., Mitchell, P., Wang, J., White, A., Keane, M., Souzeau, E., Graham, S., Goldberg, I., Healey, P., et al (2018). DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma. Ophthalmic Genetics, 39(2), 221-227. [More Information]
  • MacGregor, S., Ong, J., An, J., Han, X., Zhou, T., Siggs, O., Law, M., Souzeau, E., Sharma, S., Healey, P., White, A., Grigg, J., Goldberg, I., et al (2018). Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. Nature Genetics, 50(8), 1067-1071. [More Information]

2017

  • Zhou, T., Souzeau, E., Siggs, O., Landers, J., Mills, R., Goldberg, I., Healey, P., Graham, S., Hewitt, A., Mackey, D., et al (2017). Contribution of mutations in known mendelian glaucoma genes to advanced early-onset primary open-angle glaucoma. Investigative Ophthalmology and Visual Science, 58(3), 1537-1544. [More Information]
  • Souzeau, E., Tram, K., Witney, M., Ruddle, J., Graham, S., Healey, P., Goldberg, I., Mackey, D., Hewitt, A., Burdon, K., et al (2017). Myocilin Predictive Genetic Testing for Primary Open-Angle Glaucoma Leads to Early Identification of At-Risk Individuals. Ophthalmology, 124(3), 303-309. [More Information]
  • Dunn, H., Healey, P., Zheng, L., White, A. (2017). Refinement of needling classification for trabeculectomy blebs. Clinical and Experimental Ophthalmology, 45(4), 425-426. [More Information]

2016

  • Au, C., White, A., Healey, P. (2016). Efficacy and cost-effectiveness of intracameral vancomycin in reducing postoperative endophthalmitis incidence in Australia. Clinical and Experimental Ophthalmology, 44(9), 803-811. [More Information]
  • Ng, S., Burdon, K., Fitzgerald, J., Zhou, T., Fogarty, R., Souzeau, E., Landers, J., Mills, R., Casson, S., Ridge, B., Healey, P., Wang, J., Mitchell, P., et al (2016). Genetic association at the 9p21 glaucoma locus contributes to sex bias in normal-tension glaucoma. Investigative Ophthalmology and Visual Science, 57(7), 3416-3421. [More Information]
  • Dunn, H., Zheng, L., White, A., Healey, P. (2016). Intraoperative Transconjunctival Mitomycin-C (MMC) Application (ITMA) for needle revision of trabeculectomy. Clinical and Experimental Ophthalmology, 44(7), 640-642. [More Information]

2015

  • Burdon, K., Mitchell, P., Lee, A., Healey, P., White, A., Rochtchina, E., Thomas, P., Wang, J., Craig, J. (2015). Association of open-angle glaucoma loci with incident glaucoma in the Blue Mountains Eye Study. American Journal of Ophthalmology, 159(1), 31-36. e1. [More Information]
  • Feng, L., Roufas, A., Healey, P., White, A. (2015). Bilateral spontaneous aqueous misdirection: it can happen!. Clinical and Experimental Ophthalmology, 43(8), 771-773. [More Information]
  • Lamoureux, E., McIntosh, R., Constantinou, M., Fenwick, E., Xie, J., Casson, R., Finkelstein, E., Goldberg, I., Healey, P., Thomas, R., et al (2015). Comparing the effectiveness of selective laser trabeculoplasty with topical medication as initial treatment (the Glaucoma Initial Treatment Study): Study protocol for a randomised controlled trial. Trials, 16(1), 1-10. [More Information]

2014

  • Venturini, C., Nag, A., Hysi, P., Wang, J., Wong, T., Healey, P., Mitchell, P., Hammond, C., Viswanathan, A., et al (2014). Clarifying the role of ATOH7 in glaucoma endophenotypes. British Journal of Ophthalmology, 98(4), 562-566. [More Information]
  • Gharahkhani, P., Burden, K., Fogarty, R., Sharma, S., Hewitt, A., Martin, S., Law, M., Cremin, C., Cooke Bailey, J., Loomis, S., White, A., Goldberg, I., Healey, P., Wang, J., Mitchell, P., et al (2014). Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. Nature Genetics, 46(10), 1120-1125. [More Information]
  • Wang, X., Crowston, J., White, A., Zoellner, H., Healey, P. (2014). Interferon-alpha and Interferon-gamma modulate Fas-mediated apoptosis in Mitomycin-C resistant Human Tenon's Fibroblasts. Clinical and Experimental Ophthalmology, 42(6), 529-538. [More Information]

2013

  • Strange, A., Bellenguez, C., Sim, X., Luben, R., Hysi, P., Ramdas, W., van Koolwijk, L., Freeman, C., Pirinen, M., Su, Z., Healey, P., Wang, J., Mitchell, P., et al (2013). Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. Human Molecular Genetics, 22(22), 4653-4660. [More Information]
  • White, A., Orros, J., Healey, P. (2013). Outcomes of combined lens extraction and goniosynechialysis in angle closure. Clinical and Experimental Ophthalmology, 41(8), 746-752. [More Information]
  • White, A., Kelly, E., Healey, P., Crowston, J., Mitchell, P., Zoellner, H. (2013). P-glycoprotein Blockers Augment the Effect of Mitomycin C on Human Tenon's Fibroblasts. Translational Vision Science and Technology, 2(5), 1-9. [More Information]

2012

  • Souzeau, E., Goldberg, I., Healey, P., Mills, R., Landers, J., Graham, S., Grigg, J., Usher, B., Straga, T., Crawford, A., et al (2012). Australian and New Zealand Registry of Advanced Glaucoma: methodology and recruitment. Clinical and Experimental Ophthalmology, 40(6), 569-575. [More Information]
  • Samarawickrama, C., Pai, A., Tariq, Y., Healey, P., Wong, T., Mitchell, P. (2012). Characteristics and appearance of the normal optic nerve head in 6-year-old children. The British Journal of Ophthalmology, 96(1), 68-72. [More Information]
  • Leaney, J., Healey, P., Lee, M., Graham, S. (2012). Correlation of structural retinal nerve fibre layer parameters and functional measures using Heidelberg Retinal Tomography and Spectralis spectral domain optical coherence tomography at different levels of glaucoma severity. Clinical and Experimental Ophthalmology, 40(8), 802-812. [More Information]

2011

  • Healey, P., Mitchell, P. (2011). Author reply. Ophthalmology, 118(5), 1009-1010. [More Information]
  • Healey, P. (2011). Optic disc haemorrhage: the more we look the more we find. Clinical and Experimental Ophthalmology, 39(6), 485-486. [More Information]
  • Fahy, S., Sun, C., Zhu, G., Healey, P., Spector, T., Martin, N., Mitchell, P., Wong, T., Mackey, D., Hammond, C., et al (2011). The Relationship between Retinal Arteriolar and Venular Calibers Is Genetically Mediated, and Each Is Associated with Risk of Cardiovascular Disease. Investigative Ophthalmology and Visual Science, 52(2), 975-984. [More Information]

2010

  • Dimasi, D., Burdon, K., Hewitt, A., Savarirayan, R., Healey, P., Mitchell, P., Mackey, D., Craig, J. (2010). Candidate gene study to investigate the genetic determinants of normal variation in central corneal thickness. Molecular Vision, 16, 562-569. [More Information]
  • Rahman, M., Bunce, C., Healey, P., Mitchell, P., Sham, P., McGuffin, P., Viswanathan, A. (2010). Commingling analyses of central corneal thickness and adjusted intraocular pressure in an older Australian population. Investigative Ophthalmology and Visual Science, 51(5), 2512-2518. [More Information]
  • Lu, Y., Dimasi, D., Hysi, P., Hewitt, A., Burdon, K., Toh, T., Ruddle, J., Li, Y., Mitchell, P., Healey, P., et al (2010). Common Genetic Variants near the Brittle Cornea Syndrome Locus ZNF469 Influence the Blinding Disease Risk Factor Central Corneal Thickness. PLoS Genetics, 6(5), e1000947 - 1-e1000947 - 10. [More Information]

2009

  • Goldberg, I., Clement, C., Chiang, T., Walt, J., Lee, L., Graham, S., Healey, P. (2009). Assessing quality of life in patients with glaucoma using the Glaucoma Quality of Life-15 (GQL-15) questionnaire. Journal of Glaucoma, 18(1), 6-12. [More Information]
  • Clement, C., Goldberg, I., Healey, P., Graham, S. (2009). Humphrey matrix frequency doubling perimetry for detection of visual-field defects in open-angle glaucoma. British Journal of Ophthalmology, 93(5), 582-588. [More Information]
  • Van Koolwijk, L., Healey, P., Hitchings, R., Mitchell, P., Sham, P., McGuffin, P., Viswanathan, A. (2009). Major genetic effects in glaucoma: commingling analysis of optic disc parameters in an older Australian population. Investigative Ophthalmology and Visual Science, 50(11), 5275-5280. [More Information]

2008

  • Weinreb, R., Healey, P., Topouzis, F. (2008). Glaucoma Screening. Amsterdam, The Netherlands: Kugler Publications.
  • Irwig, L., Healey, P., D'Assuncao, J., Macaskill, P. (2008). Monitoring intraocular pressure in glaucoma. In P Glasziou, L Irwig and J K Aronson (Eds.), Evidence-based Medical Monitoring:From Principles to Practice, (pp. 325-334). Oxford: Blackwell Publishers. [More Information]
  • Healey, P., Carbonaro, F., Taylor, B., Spector, T., Mitchell, P., Hammond, C. (2008). The heritability of optic disc parameters: a classic twin study. Investigative Ophthalmology and Visual Science, 49(1), 77-80. [More Information]

2007

  • Healey, P. (2007). Glaucoma: time to talk to the family. Clinical and Experimental Ophthalmology, 35(9), 790-790. [More Information]
  • Tong, L., Chan, Y., Gazzard, G., Loon, S., Fong, A., Selvaraj, P., Healey, P., Tan, D., Wong, T., Saw, S. (2007). Heidelberg retinal tomography of optic disc and nerve fiber layer in singapore children: variations with disc tilt and refractive error. Investigative Ophthalmology and Visual Science, 48(11), 4939-4944. [More Information]
  • Wang, X., Crowston, J., Zoellner, H., Healey, P. (2007). Interferon-α and interferon-γ sensitize human tenon fibroblasts to mitomycin-C. Investigative Ophthalmology and Visual Science, 48(8), 3655-3661. [More Information]

2006

  • Crowston, J., Wang, X., Khaw, P., Zoellner, H., Healey, P. (2006). Human serum reduces mitomycin-C cytototoxicity in Human tenon's Fibroblasts. Investigative Ophthalmology and Visual Science, 47(3), 946-952. [More Information]
  • Fung, A., Reid, S., Jones, M., Craig, J., Healey, P., McCluskey, P. (2006). Meta-analysis of randomised controlled trials comparing latanoprost with brimonidine in the treatment of open angle glaucoma, ocular hypertension or normal tension glaucoma. British Journal of Ophthalmology, 91(1), 62-68. [More Information]
  • Luo, H., Gazzard, G., Fong, A., Aung, T., Hoh, S., Loon, S., Healey, P., Tan, D., Wong, T., Saw, S. (2006). Myopia, axial length, and OCT characteristics of the macula in Singaporean children. Investigative Ophthalmology and Visual Science, 47(7), 2773-2781. [More Information]

2005

  • Healey, P., Trope, G. (2005). The Failing Bleb: Diagnosis and management. In Trope G (Eds.), Glaucoma Surgery, (pp. 159-178). United States: Taylor & Francis.

2004

  • Tumuluri, K., Woo, T., Crowston, J., Healey, P., Gottlieb, D., Maloof, A. (2004). Bilateral leukemic orbital infiltration presenting as proptosis and narrow-angle glaucoma. Ophthalmic Plastic and Reconstructive Surgery, 20(3), 248-250. [More Information]
  • Viswanathan, A., Hitchings, R., Indar, A., Mitchell, P., Healey, P., McGuffin, P., Sham, P. (2004). Commingling Analysis Of Intraocular Pressure And Glaucoma In An Older Australian Population. Annals of Human Genetics, 68(5), 489-497. [More Information]
  • Lee, A., Rochtchina, E., Wang, J., Healey, P., Mitchell, P. (2004). Open-Angle Glaucoma And Systemic Thyroid Disease In An Older Population: The Blue Mountains Eye Study. Eye, 18(6), 600-608. [More Information]

2003

  • Lee, A., Rochtchina, E., Wang, J., Healey, P., Mitchell, P. (2003). Does smoking affect introcular pressure? Findings from the Blue Mountains Eye Study. Journal of Glaucoma, 12(3), 209-212. [More Information]
  • Lee, A., Mitchell, P., Rochtchina, E., Healey, P. (2003). Female reproductive factors and open angle glaucoma;the Blue Mountains Eye Study. British Journal of Ophthalmology, 87, 1324-1328. [More Information]
  • Lee, A., Wang, J., Rochtchina, E., Healey, P., Chia, E., Mitchell, P. (2003). Patterns of glaucomatous visual field defects in an older paopulation: the Blue Mountains Eye Study. Clinical and Experimental Ophthalmology, 31(4), 331-335. [More Information]

2002

  • Gilhotra, J., Mitchell, P., Healey, P., Cumming, R., Currie, J. (2002). Homonymous visual field defects and stroke in an older population. Stroke, 33(10), 2417-2420. [More Information]
  • Goldberg, I., Graham, S., Healey, P. (2002). Primary open-angle glaucoma: Early diagnosis of this otherwise progressive, asymptomatic process is essential. Medical Journal of Australia, 177, 535-536. [More Information]

Selected Grants

2012

  • Towards translation of glaucoma blindness genes into clinical practice: Predicting Risk of Glaucoma: Relevant SNPs with Strong Association (PROGRESSA) Study , Craig J, Healey P, National Health and Medical Research Council (NHMRC)/Project Grants
  • Systematic glaucoma screening and diagnostic effectiveness: improving patient outcomes through early detection, Healey P, Mitchell P, Kalloniatis M, National Health and Medical Research Council (NHMRC)/Partnership Projects

Publications as a co-author ofANZRAGConsortium

2021

2018

  • Bailey J. N .C. et.al (2018). Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets, Investigative Ophthalmology and Visual Science(IOVS), 59(2), 629-636. doi: 10.1167/iovs.17-22708.

2016

  • Bailey, J. N .C. et.al (2016). Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open angle glaucoma, Nature Genetics. 48(2): 189–194. doi:10.1038/ng.3482.