2024

• Lv, K., Chen, S., Xu, X., Chiu, J., Wang, H., Han, Y., Yang, X., Bowley, S., Wang, H., Tang, Z., Ju, A., Hogg, P., et al (2024). Protein disulfide isomerase cleaves allosteric disulfides in histidine-rich glycoprotein to regulate thrombosis. Nature Communications, 15(1). [More Information]

2023

• Kutzki, F., Butera, D., Lay, A., Maag, D., Chiu, J., Woon, H., Kubař, T., Elstner, M., Aponte-Santamaria, C., Hogg, P., et al (2023). Disulfide bond reduction and exchange in C4 domain of von Willebrand factor undermines platelet binding. Journal of Thrombosis and Haemostasis, 21(8), 2089-2100. [More Information]
• Lay, A., Dupuy, A., Hagimola, L., Tieng, J., Larance, M., Zhang, Y., Yang, J., Kong, Y., Chiu, J., Gray, E., Maclean, J., Hofma, B., Jackson, S., Hogg, P., Passam, F., et al (2023). Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model. Blood Advances, 7(9), 1650-1665. [More Information]
• Ho Shon, I., Hogg, P. (2023). Imaging of cell death in malignancy: Targeting pathways or phenotypes? Nuclear Medicine and Biology, 124-125. [More Information]
• Seneviratne, J., Carter, D., Mittra, R., Gifford, A., Kim, P., Luo, J., Mayoh, C., Salib, A., Rahmanto, A., Murray, J., Hogg, P., et al (2023). Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma. International Journal of Cancer, 152(7), 1399-1413. [More Information]
• Butera, D., Wang, H., Woon, H., Zhao, C., Ju, A., Hogg, P. (2023). Mechano-covalent protection of coagulation factor VIII by von Willebrand factor. Blood Advances, 7(10), 2117-2128. [More Information]
• Dupuy, A., Aponte-Santamaría, C., Yeheskel, A., Hortle, E., Oehlers, S., Grater, F., Hogg, P., Passam, F., Chiu, J. (2023). Mechano-Redox Control of Mac-1 De-Adhesion by PDI Promotes Directional Movement under Flow. Circulation Research, 132(9), E151-E168. [More Information]
• Yang, M., Chiu, J., Scartelli, C., Ponzar, N., Patel, S., Patel, A., Ferreira, R., Keyes, R., Carroll, K., Pozzi, N., Hogg, P., et al (2023). Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation. Journal of Thrombosis and Haemostasis, 21(8), 2137-2150. [More Information]

2022

• Ho Shon, I., Hennessy, T., Guille, J., Gotsbacher, M., Lay, A., McBride, B., Codd, R., Hogg, P. (2022). A first-in-human study of [68Ga]Ga-CDI: a positron emitting radiopharmaceutical for imaging tumour cell death. European Journal of Nuclear Medicine and Molecular Imaging, 49(12), 4037-4047. [More Information]
• Pijning, A., Butera, D., Hogg, P. (2022). Not one, but many forms of thrombosis proteins. Journal of Thrombosis and Haemostasis, 20(2), 285-292. [More Information]
• Ho Shon, I., Kumar, D., Schreuder, M., Guille, J., Doan, J., Sathikumar, C., Van, K., Chicco, A., Hogg, P. (2022). Preclinical Assessment of [68Ga]Ga-Cell Death Indicator (CDI): A Novel hsp90 Ligand for Positron Emission Tomography of Cell Death. Current Radiopharmaceuticals, 15(3), 184-193. [More Information]

2021

• Sarkar, S., Tran, B., Horvath, L., Lam, M., Savas, P., Grimison, P., Whittle, J., Kuo, J., Edmonds, D., Hogg, P., et al (2021). A phase 1 trial of 4-(N-(S-penicillaminylacetyl)amino)-phenylarsonous acid (PENAO) in patients with advanced solid tumours. Cancer Chemotherapy and Pharmacology, 87(5), 613-620. [More Information]
• Pijning, A., Blyth, M., Coote, M., Passam, F., Chiu, J., Hogg, P. (2021). An alternate covalent form of platelet αIIbβ3 integrin that resides in focal adhesions and has altered function. Blood, 138(15), 1359-1372. [More Information]
• Krishnaswamy, S., Ageno, W., Arabi, Y., Barbui, T., Cannegieter, S., Carrier, M., Cleuren, A., Collins, P., Panicot-Dubois, L., Freedman, J., Hogg, P., et al (2021). Illustrated State-of-the-Art Capsules of the ISTH 2021 Congress. Research and Practice in Thrombosis and Haemostasis, 5(5), e12532. [More Information]
• Florido, M., Chiu, J., Hogg, P. (2021). Influenza A Virus Hemagglutinin Is Produced in Different Disulfide-Bonded States. Antioxidants & Redox Signaling, 35(13), 1081-1092. [More Information]
• Hogg, P. (2021). Toxicokinetics of the tumour cell mitochondrial toxin, PENAO, in rodents. Investigational New Drugs, 39(3), 756-763. [More Information]

2020

• Ho Shon, I., Kumar, D., Sathiakumar, C., Berghofer, P., Van, K., Chicco, A., Hogg, P. (2020). Biodistribution and imaging of an hsp90 ligand labelled with 111In and 67Ga for imaging of cell death. EJNMMI Research, 10(1), 4. [More Information]
• Butera, D., Hogg, P. (2020). Fibrinogen function achieved through multiple covalent states. Nature Communications, 11(1), 5468. [More Information]
• Hogg, P. (2020). Multiple Disulfide-Bonded States of Native Proteins: Estimate of Number Using Probabilities of Disulfide Bond Formation. Molecules, 25(23). [More Information]
• Aji, G., Huang, Y., Ng, M., Wang, W., Lan, T., Li, M., Li, Y., Chen, Q., Li, R., Yan, S., Tran, C., Burchfield, J., Couttas, T., Chen, J., Chung, L., Liu, D., Wadham, C., Hogg, P., Vadas, M., Gamble, J., Don, A., Qi, J., et al (2020). Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2. Proceedings of the National Academy of Sciences of the United States of America, 117(39), 24434-24442. [More Information]
• Lu, Z., Chiu, J., Lee, L., Schindeler, A., Jackson, M., Ramaswamy, Y., Dunstan, C., Hogg, P., Zreiqat, H. (2020). Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7. Stem Cells Translational Medicine, 9(3), 403-415. [More Information]
• Wang, X., Yeo, R., Hogg, P., Goldstein, D., Crowe, B., Dilda, P., Yang, J. (2020). The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas. Oncotarget, 11(1), 46-61. [More Information]

2019

• Chiu, J., Hogg, P. (2019). Allosteric disulfides: Sophisticated molecular structures enabling flexible protein regulation. Journal of Biological Chemistry, 294(8), 2949-2960. [More Information]
• Pijning, A., Hogg, P. (2019). Classification of Protein Disulphide Bonds. Methods in Molecular Biology, 1967, 1-8. [More Information]
• Su, Z., Burchfield, J., Yang, P., Humphrey, S., Yang, G., Francis, D., Yasmin, S., Shin, S., Norris, D., Kearney, A., Astore, M., Scavuzzo, J., Wang, Q., Parker, B., Neely, G., Vafaee, F., Chiu, J., Yeo, R., Hogg, P., Fazakerley, D., Kuyucak, S., James, D., et al (2019). Global redox proteome and phosphoproteome analysis reveals redox switch in Akt. Nature Communications, 10(1), 1-18. [More Information]
• Lynch, J., Salik, B., Connerty, P., Vick, B., Leung, H., Pijning, A., Jeremias, I., Spiekermann, K., Trahair, T., Liu, T., Hogg, P., et al (2019). JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis. Leukemia, 33(6), 1400-1410. [More Information]
• Li, J., Kim, K., Jeong, S., Chiu, J., Xiong, B., Petukhov, P., Dai, X., Li, X., Andrews, R., Du, X., Hogg, P., et al (2019). Platelet Protein Disulfide Isomerase Promotes Glycoprotein Ibα-Mediated Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions. Circulation, 139(10), 1300-1319. [More Information]
• Ho Shon, I., Gotsbacher, M., Guille, J., Kumar, D., Codd, R., Hogg, P. (2019). Preparation of a Dithiol-Reactive Probe for PET Imaging of Cell Death. Methods in Molecular Biology, 1967, 295-304. [More Information]
• Eriksson, O., Chiu, J., Hogg, P., Atkinson, J., Liszewski, M., Flaumenhaft, R., Furie, B. (2019). Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation. Journal of Biological Chemistry, 294(13), 4878-4888. [More Information]
• Hogg, P. (2019). TMX1: A new vascular thiol isomerase. Blood, 133(3), 188-190. [More Information]

2018

• Butera, D., Passam, F., Ju, A., Cook, K., Woon, H., Aponte-Santamaria, C., Gardiner, E., Davis, A., Murphy, D., Bronowska, A., Jackson, S., Hogg, P., et al (2018). Autoregulation of von Willebrand factor function by a disulfide bond switch. Science Advances, 4(2), 1-12. [More Information]
• Noy, J., Lu, H., Hogg, P., Yang, J., Stenzel, M. (2018). Direct Polymerization of the Arsenic Drug PENAO to Obtain Nanoparticles with High Thiol-Reactivity and Anti-Cancer Efficiency. Bioconjugate Chemistry, 29(2), 546-558. [More Information]
• Tsoli, M., Liu, J., Franshaw, L., Shen, H., Cheng, C., Jung, M., Joshi, S., Ehteda, A., Khan, A., Montero-Carcabosso, A., Hogg, P., et al (2018). Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma. Oncotarget, 9(7), 7541-7556. [More Information]
• Quinlan, R., Hogg, P. (2018). Gamma-Crystallin redox– detox in the lens. Journal of Biological Chemistry, 293(46), 18010-18011. [More Information]
• Pijning, A., Chiu, J., Yeo, R., Wong, J., Hogg, P. (2018). Identification of allosteric disulfides from labile bonds in X-ray structures. Royal Society Open Science, 5(2), 1-13. [More Information]
• Passam, F., Chiu, J., Ju, A., Pijning, A., Jahan, Z., Mor-Cohen, R., Yeheskel, A., Kolsek, K., Tharichen, L., Aponte-Santamaria, C., Hogg, P., et al (2018). Mechano-redox control of integrin de-adhesion. eLife, 7, 1-22. [More Information]
• Pasalic, L., Wing-Luna, E., Lau, J., Campbell, H., Pennings, G., Lau, E., Connor, D., Liang, H., Muller, D., Kritharides, L., Hogg, P., Chen, V. (2018). Novel assay demonstrates that coronary artery disease patients have heightened procoagulant platelet response. Journal of Thrombosis and Haemostasis, 16(6), 1198-1210. [More Information]
• Bekendam, R., Iyu, D., Passam, F., Stopa, J., De Ceunynck, K., Muse, O., Bendapudi, P., Garnier, C., Gopal, S., Chiu, J., Hogg, P., et al (2018). Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation. Journal of Thrombosis and Haemostasis, 16(11), 2322-2335. [More Information]

2017

• Zhou, B., Hogg, P., Grater, F. (2017). One-Way Allosteric Communication between the Two Disulfide Bonds in Tissue Factor. Biophysical Journal, 112(1), 78-86. [More Information]
• Read, S., O'Connor, K., Suppiah, V., Ahlenstiel, C., Obeid, S., Cook, K., Cunningham, A., Douglas, M., Hogg, P., Booth, D., George, J., Ahlenstiel, G. (2017). Zinc is a potent and specific inhibitor of IFN-(lambda)3 signaling. Nature Communications, 8, 1-15. [More Information]

2016

• Bekendam, R., Bendapudi, P., Lin, L., Nag, P., Pu, J., Kennedy, D., Feldenzer, A., Chiu, J., Cook, K., Furie, B., Hogg, P., et al (2016). A substrate-driven allosteric switch that enhances PDI catalytic activity. Nature Communications, 7, 1-11. [More Information]

2015

• Decollogne, S., Joshi, S., Chung, S., Luk, P., Yeo, R., Nixdorf, S., Fedier, A., Heinzelmann-Schwarz, V., Hogg, P., Dilda, P. (2015). Alterations in the mitochondrial responses to PENAO as a mechanism of resistance in ovarian cancer cells. Gynecologic Oncology, 138(2), 363-371. [More Information]
• Shen, H., Decollogne, S., Dilda, P., Hau, E., Chung, S., Luk, P., Hogg, P., McDonald, K. (2015). Dual-targeting of aberrant glucose metabolism in glioblastoma. Journal of Experimental and Clinical Cancer Research, 34(1), 14. [More Information]
• Hua, V., Abeynaike, L., Glaros, E., Campbell, H., Pasalic, L., Hogg, P., Chen, V. (2015). Necrotic platelets provide a procoagulant surface during thrombosis. Blood, 126(26), 2852-2862. [More Information]
• Wilson, P., Anastasaki, A., Owen, M., Kempe, K., Haddleton, D., Mann, S., Johnston, A., Quinn, J., Whittaker, M., Hogg, P., et al (2015). Organic arsenicals as efficient and highly specific linkers for protein/peptide-polymer conjugation. Journal of the American Chemical Society, 137(12), 4215-4222. [More Information]
• Chiu, J., Passam, F., Butera, D., Hogg, P. (2015). Protein Disulfide Isomerase in Thrombosis. Seminars in Thrombosis and Hemostasis, 41(7), 765-773. [More Information]
• Lu, D., Arulmozhiraja, S., Coote, M., Rae, A., Salem, G., Willis, A., Wild, S., Benhenda, S., Breitenbach, V., De Thé, H., et al (2015). Sulfur derivatives of the natural polyarsenical arsenicin a: Biologically active, organometallic arsenic-sulfur cages related to the minerals realgar and uzonite. Organometallics, 34(5), 829-840. [More Information]

2014

• Butera, D., Wind, T., Lay, A., Beck, J., Castellino, F., Hogg, P. (2014). Characterization of a reduced form of plasma plasminogen as the precursor for angiostatin formation. Journal of Biological Chemistry, 289(5), 2992-3000. [More Information]
• Butera, D., Cook, K., Chiu, J., Wong, J., Hogg, P. (2014). Control of blood proteins by functional disulfide bonds. Blood, 123(13), 2000-2007. [More Information]
• Ramsay, E., Decollogne, S., Joshi, S., Corti, A., Apte, M., Pompella, A., Hogg, P., Dilda, P. (2014). Employing Pancreatic Tumor y-Glutamyltransferase for Therapeutic Delivery. Molecular Pharmaceutics, 11(5), 1500-1511. [More Information]
• Chiu, J., Wong, J., Gerometta, M., Hogg, P. (2014). Mechanism of dimerization of a recombinant mature vascular endothelial growth factor C. Biochemistry, 53(1), 7-9. [More Information]
• Chiu, J., Wong, J., Hogg, P. (2014). Redox Regulation of Methionine Aminopeptidase 2 Activity. Journal of Biological Chemistry, 289(21), 15035-15043. [More Information]
• Gang, B., Dilda, P., Hogg, P., Blackburn, A. (2014). Targeting of two aspects of metabolism in breast cancer treatment. Cancer Biology and Therapy, 15(11), 1533-1541. [More Information]

2013

• Horsley, L., Cummings, J., Middleton, M., Ward, T., Backen, A., Clamp, A., Dawson, M., Farmer, H., Fisher, N., Halbert, G., et al (2013). A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours. Cancer Chemotherapy and Pharmacology, 72(6), 1343-1352. [More Information]
• Cook, K., McNeil, H., Hogg, P. (2013). Allosteric control of betaII-tryptase by a redox active disulfide bond. Journal of Biological Chemistry, 288(48), 34920-34929. [More Information]
• Dick, L., Gray, A., Ram, A., Hume, A., Parris, C., Hogg, P., Elliott, M., Ford, S., Halbert, G. (2013). Elimination of the antimicrobial action of the organoarsenical cancer therapeutic, 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid, before finished product sterility testing. Journal of Pharmacy and Pharmacology, 65(11), 1664-1669. [More Information]
• Chen, V., Hogg, P. (2013). Encryption and decryption of tissue factor. Journal of Thrombosis and Haemostasis, 11(Suppl 1), 277-284. [More Information]
• Xie, B., Park, D., Van Beek, E., Blankevoort, V., Orabi, Y., Que, I., Kaijzel, E., Chan, A., Hogg, P., Lowik, C. (2013). Optical imaging of cell death in traumatic brain injury using a heat shock protein-90 alkylator. Cell Death and Disease, 4, 1-8. [More Information]
• Park, D., Xie, B., Van Beek, E., Blankevoort, V., Que, I., Löwik, C., Hogg, P. (2013). Optical imaging of treatment-related tumor cell death using a heat shock protein-90 alkylator. Molecular Pharmaceutics, 10(10), 3882-3891. [More Information]
• Cook, K., Hogg, P. (2013). Post-translational control of protein function by disulfide bond cleavage. Antioxidants & Redox Signaling, 18(15), 1987-2015. [More Information]
• Hogg, P. (2013). Targeting allosteric disulphide bonds in cancer. Nature Reviews. Cancer, 13(6), 425-431. [More Information]
• Ng, J., Chiu, J., Hogg, P., Wong, J. (2013). Tyrosine nitration moderates the peptidase activity of human methionyl aminopeptidase 2. Biochemical and Biophysical Research Communications, 440(1), 37-42. [More Information]

2012

• Park, D., Chiu, J., Perrone, G., Dilda, P., Hogg, P. (2012). The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase. Cancer Cell International, 12(1), 1-6. [More Information]

2011

• Wong, J., Ho, S., Hogg, P. (2011). Disulfide bond acquisition through eukaryotic protein evolution. Molecular Biology and Evolution, 28(1), 327-334. [More Information]
• Ganderton, T., Wong, J., Schroeder, C., Hogg, P. (2011). Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain. Blood, 118(19), 5312-5318. [More Information]
• Park, D., Don, A., Massamiri, T., Karwa, A., Warner, B., MacDonald, J., Hemenway, C., Naik, A., Kuan, K., Hogg, P., et al (2011). Noninvasive imaging of cell death using an Hsp90 ligand. Journal of the American Chemical Society, 133(9), 2832-2835. [More Information]
• Scott, A., O'Dea, K., O'Callaghan, D., Williams, L., Dokpesi, J., Tatton, L., Handy, J., Hogg, P., Takata, M. (2011). Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor alpha-converting enzyme (TACE/ADAM-17) activation in primary human monocytes. Journal of Biological Chemistry, 286(41), 35466-35476. [More Information]

2010

• Passam, F., Rahgozar, S., Qi, M., Raftery, M., Wong, J., Tanaka, K., Ioannou, Y., Zhang, J., Gemmell, R., Hogg, P., et al (2010). Beta 2 glycoprotein I is a substrate of thiol oxidoreductases. Blood, 116(11), 1995-1997. [More Information]
• Ioannou, Y., Zhang, J., Passam, F., Rahgozar, S., Qi, J., Giannakopoulos, B., Qi, M., Yu, P., Yu, D., Hogg, P., et al (2010). Naturally occurring free thiols within {beta}2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells and regulation of oxidative stress induced cell injury. Blood, 116(11), 1961-1970. [More Information]
• Matthias, L., Azimi, I., Tabrett, C., Hogg, P. (2010). Reduced monomeric CD4 is the preferred receptor for HIV. Journal of Biological Chemistry, 285(52), 40793-40799. [More Information]
• Azimi, I., Matthias, L., Center, R., Wong, J., Hogg, P. (2010). The disulfide bond that constrains the HIV-1 gp120 V3 domain is cleaved by thioredoxin. Journal of Biological Chemistry, 285(51), 40072-40080. [More Information]

2009

• Dilda, P., Decollogne, S., Weerakoon, L., Norris, M., Haber, M., Allen, J., Hogg, P. (2009). Optimization of the antitumor efficacy of a synthetic mitochondrial toxin by increasing the residence time in the cytosol. Journal of Medicinal Chemistry, 52(20), 6209-6216. [More Information]