Professor Philip Barter
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Professor Philip Barter

Professor
Medicine, Central Clinical School
Heart Research Institute
Phone
+61 2 9550 3560
Fax
+61 2 9550 3302

Publications

Book Chapters

  • Barter, P. (2009). Evolving Targets of Therapy. In Christie M Ballantyne (Eds.), Clinical Lipidology: A Companion to Braunwalds Heart Disease, (pp. 387-395). Philadelphia, USA: Saunders Elsevier.
  • Barter, P., Rye, K. (2009). High-density lipoprotein as a therapeutic target. In Tonkin, Andrew (Eds.), Therepeutic Strategies: Lipid Disorders, (pp. 29-42). United Kingdom: Clinical Publishing, Oxford.
  • Barter, P., Rye, K. (2007). HDL and Atherosclerosis. In Christopher J Fielding (Eds.), High Density Lipoproteins: From Basic Biology to Clinical Aspects, (pp. 491-505). Germany: Wiley - V C H Verlag GmbH & Co. KGaA. [More Information]

Journals

  • Lee, Z., Llanes, E., Sukmawan, R., Thongtang, N., Ho, H., Barter, P. (2021). Prevalence of plasma lipid disorders with an emphasis on LDL cholesterol in selected countries in the Asia-Pacific region. Lipids in Health and Disease, 20(1), 33. [More Information]
  • Januszewski, A., Chen, D., Scott, R., O'Connell, R., Aryal, N., Sullivan, D., Watts, G., Taskinen, M., Barter, P., Best, J., Simes, R., Keech, A., Jenkins, A. (2021). Relationship of low molecular weight fluorophore levels with clinical factors and fenofibrate effects in adults with type 2 diabetes. Scientific Reports, 11(1), 18708. [More Information]
  • Tucker, B., McClelland, R., Allison, M., Budoff, M., Wu, B., Barter, P., Rye, K., Ong, K. (2020). Relationship of fibroblast growth factor 21 levels with inflammation, lipoproteins and non-alcoholic fatty liver disease. Atherosclerosis, 299, 38-44. [More Information]

Conferences

  • Nobecourt, E., Puranik, R., Bao, B., Davies, M., Barter, P., Rye, K. (2006). Evidence that glycation of apolipoprotein. XIV International Symposium on Atherosclerosis, Ireland: Elsevier Ireland Ltd.

2021

  • Lee, Z., Llanes, E., Sukmawan, R., Thongtang, N., Ho, H., Barter, P. (2021). Prevalence of plasma lipid disorders with an emphasis on LDL cholesterol in selected countries in the Asia-Pacific region. Lipids in Health and Disease, 20(1), 33. [More Information]
  • Januszewski, A., Chen, D., Scott, R., O'Connell, R., Aryal, N., Sullivan, D., Watts, G., Taskinen, M., Barter, P., Best, J., Simes, R., Keech, A., Jenkins, A. (2021). Relationship of low molecular weight fluorophore levels with clinical factors and fenofibrate effects in adults with type 2 diabetes. Scientific Reports, 11(1), 18708. [More Information]

2020

  • Tucker, B., McClelland, R., Allison, M., Budoff, M., Wu, B., Barter, P., Rye, K., Ong, K. (2020). Relationship of fibroblast growth factor 21 levels with inflammation, lipoproteins and non-alcoholic fatty liver disease. Atherosclerosis, 299, 38-44. [More Information]

2019

  • Hui, N., Barter, P., Ong, K., Rye, K. (2019). Altered HDL metabolism in metabolic disorders: Insights into the therapeutic potential of HDL. Clinical Science, 133(21), 2221-2235. [More Information]
  • Wu, B., Sun, Y., Ong, K., Li, Y., Tang, S., Barter, P., Rye, K. (2019). Apolipoprotein A-I Protects Against Pregnancy-Induced Insulin Resistance in Rats. Arteriosclerosis, Thrombosis, and Vascular Biology, 39(6), 1160-1171. [More Information]
  • Hou, L., Tang, S., Wu, B., Ong, K., Westerterp, M., Barter, P., Cochran, B., Tabet, F., Rye, K. (2019). Apolipoprotein A-l improves pancreatic β-cell function independent of the ATP-binding cassette transporters ABCA1 and ABCG1. The FASEB Journal, 33(7), 8479-8489. [More Information]

2018

  • Nicholls, S., Lincoff, A., Bash, D., Ballantyne, C., Barter, P., Davidson, M., Kastelein, J., Koenig, W., Mcguire, D., Mozaffarian, D., et al (2018). Assessment of Omega-3 Carboxylic Acids in Statin Treated Patients with High Levels of Triglycerides and Low Levels of High Density Lipoprotein Cholesterol: Rationale and Design of the STRENGTH Trial. Clinical Cardiology, 41(10), 1281-1288. [More Information]
  • Barter, P., Cochran, B., Rye, K. (2018). CETP inhibition, statins and diabetes. Atherosclerosis, 278, 143-146. [More Information]
  • Shrestha, S., Wu, B., Guiney, L., Barter, P., Rye, K. (2018). Cholesteryl ester transfer protein and its inhibitors. Journal of Lipid Research, 59(5), 772-783. [More Information]

2017

  • Ong, K., O'Connell, R., Januszewski, A., Jenkins, A., Xu, A., Sullivan, D., Barter, P., Scott, R., Taskinen, M., Waldman, B., Simes, R., Rye, K., Keech, A., et al (2017). Baseline circulating FGF21 concentrations and increase after fenofibrate treatment predict more rapid glycemic progression in type 2 diabetes: Results from the FIELD study. Clinical Chemistry, 63(7), 1261-1270. [More Information]
  • Cochran, B., Ryder, W., Parmar, A., Klaeser, K., Reilhac, A., Angelis, G., Meikle, S., Barter, P., Rye, K. (2017). Determining glucose metabolism kinetics using 18F-FDG micro-PET/CT. Journal of Visualized Experiments, May 2017(123), 1-6. [More Information]
  • Wu, B., Li, Y., Ong, K., Sun, Y., Shrestha, S., Hou, L., Johns, D., Barter, P., Rye, K. (2017). Reduction of in-stent restenosis by cholesteryl ester transfer protein inhibition. Arteriosclerosis, Thrombosis, and Vascular Biology, 37(12), 2333-2341. [More Information]

2016

  • Puranik, R., Bao, B., Bonin, A., Kaur, R., Weder, J., Casbolt, L., Hambley, T., Lay, P., Barter, P., Rye, K. (2016). A novel class of copper(II)- and zinc(II)-bound non-steroidal anti-inflammatory drugs that inhibits acute inflammation in vivo. Cell and Bioscience, 6(1), 1-7. [More Information]
  • Tabet, F., Torres, L., Ong, K., Shrestha, S., Choteau, S., Barter, P., Clifton, P., Rye, K. (2016). High-density lipoprotein-associated miR-223 is altered after diet-induced weight loss in overweight and obese males. PloS One, 11(3). [More Information]
  • Cochran, B., Hou, L., Manavalan, A., Moore, B., Tabet, F., Sultana, A., Cuesta Torres, L., Tang, S., Shrestha, S., et al, Barter, P., Rye, K. (2016). Impact of perturbed pancreatic (beta)-cell cholesterol homeostasis on adipose tissue and skeletal muscle metabolism. Diabetes, 65(12), 3610-3620. [More Information]

2015

  • Bisoendial, R., Tabet, F., Tak, P., Petrides, F., Torres, L., Hou, L., Cook, A., Barter, P., Weninger, W., Rye, K. (2015). Apolipoprotein A-I Limits the Negative Effect of Tumor Necrosis Factor on Lymphangiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology, 35(11), 2443-2450. [More Information]
  • Wu, B., Shrestha, S., Ong, K., Johns, D., Hou, L., Barter, P., Rye, K. (2015). Cholesteryl ester transfer protein inhibition enhances endothelial repair and improves endothelial function in the rabbit. Arteriosclerosis, Thrombosis, and Vascular Biology, 35(3), 628-636. [More Information]
  • Sullivan, D., Watts, G., Nicholls, S., Barter, P., Grenfell, R., Chow, C., Tonkin, A., Keech, A. (2015). Clinical Guidelines on Hyperlipidaemia: Recent Developments, Future Challenges and the Need for an Australian Review. Heart, Lung, and Circulation, 24(5), 495-502. [More Information]

2014

  • Cochrane, B., Bisoendial, R., Hou, L., Glaros, E., Rossy, J., Thomas, S., Barter, P., Rye, K. (2014). Apolipoprotein a-I increases Insulin Secretion and Production from Pancreatic β-cells via a G-protein-cAMP-PKA-FoxO1- Dependent Mechanism. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(10), 2261-2267. [More Information]
  • Ong, K., Barter, P., Waters, D. (2014). Cardiovascular drugs that increase the risk of new-onset diabetes. American Heart Journal, 167(4), 421-428. [More Information]
  • Ong, K., Waters, D., Messig, M., DeMicco, D., Rye, K., Barter, P. (2014). Effect of Change in Body Weight on Incident Diabetes Mellitus in Patients With Stable Coronary Artery Disease Treated With Atorvastatin (from the Treating to New Targets Study). American Journal of Cardiology, 113(10), 1593-1598. [More Information]

2013

  • Ong, K., Wu, B., Cheung, B., Barter, P., Rye, K. (2013). Arthritis: Its prevalence, risk factors, and association with cardiovascular diseases in the United States, 1999 to 2008. Annals of Epidemiology, 23(2), 80-86. [More Information]
  • Wu, B., Chen, K., Shrestha, S., Ong, K., Barter, P., Rye, K. (2013). High Density Lipoproteins Inhibit Vascular Endothelial Inflammation by Increasing 3[beta]-Hydroxysteroid-{Delta}24 Reductase Expression and Inducing Heme Oxygenase-1. Circulation Research, 112(2), 278-288. [More Information]
  • Ong, K., Allison, M., Cheung, B., Wu, B., Barter, P., Rye, K. (2013). Trends in C-Reactive Protein Levels in US Adults From 1999 to 2010. American Journal of Epidemiology, 177(12), 1430-1442. [More Information]

2012

  • Nicholls, S., Gordon, A., Johannson, J., Ballantyne, C., Barter, P., Brewer, H., Kastelein, J., Wong, N., Borgman, M., Nissen, S. (2012). ApoA-I Induction as a Potential Cardioprotective Strategy: Rationale for the SUSTAIN and ASSURE Studies. Cardiovascular Drugs and Therapy, 26(2), 181-187. [More Information]
  • Morales-Villegas, E., Moreno-Virgen, G., Barter, P. (2012). CETP pharmacological manipulation transforming human into mouse: Is this still a viable hypothesis? Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, 12(4), 266-278. [More Information]
  • Barter, P., Rye, K. (2012). Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk. Journal of Lipid Research, 53(9), 1755-1766. [More Information]

2011

  • Ong, K., Wu, B., Cheung, B., Barter, P., Rye, K. (2011). Association of lower total bilirubin level with statin usage: The United States National Health and Nutrition Examination Survey 1999-2008. Atherosclerosis, 219(2), 728-733. [More Information]
  • Barter, P., Rye, K. (2011). Cholesteryl ester transfer protein inhibition to reduce cardiovascular risk: where are we now? Trends In Pharmacological Sciences, 32(12), 694-699. [More Information]
  • Chan, J., Chan, S., Deerochanawong, C., Go, R., Lee, K., Ma, R., Pan, C., Sheu, W., Barter, P. (2011). Diabetic dyslipidaemia in Asian populations in the Western Pacific Region: What we know and don't know. Diabetes Research and Clinical Practice, 94(1), 1-13. [More Information]

2010

  • Taskinen, M., Barter, P., Ehnholm, C., Sullivan, D., Robledo, K., Simes, R., Best, J., Hamwood, S., Keech, A. (2010). Ability of traditional lipid ratios and apolipoprotein ratios to predict cardiovascular risk in people with type 2 diabetes. Diabetologia, 53(9), 1846-1855. [More Information]
  • Patel, S., Di Bartolo, B., Nakhla, S., Heather, A., Mitchell, T., Jessup, W., Celermajer, D., Barter, P., Rye, K. (2010). Anti-inflammatory effects of apolipoprotein A-I in the rabbit. Atherosclerosis, 212(2), 392-397. [More Information]
  • Barter, P., Brandrup-Wognsen, G., Palmer, M., Nicholls, S. (2010). Effect of statins on HDL-C: a complex process unrelated to changes in LDL-C: analysis of the VOYAGER Database. Journal of Lipid Research, 51(6), 1546-1553. [More Information]

2009

  • Patel, S., Puranik, R., Nakhla, S., Lundmand, P., Stocker, R., Wang, X., Lambert, G., Rye, K., Barter, P., Nicholls, S., Celermajer, D. (2009). Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-inflammatory capacity of high density lipoproteins. Atherosclerosis, 204(2), 424-428. [More Information]
  • Fryirs, M., Barter, P., Rye, K. (2009). Cholesterol metabolism and pancreatic B-cell function. Current Opinion in Lipidology, 20(3), 159-164. [More Information]
  • Barter, P. (2009). Evolving Targets of Therapy. In Christie M Ballantyne (Eds.), Clinical Lipidology: A Companion to Braunwalds Heart Disease, (pp. 387-395). Philadelphia, USA: Saunders Elsevier.

2008

  • Rye, K., Barter, P. (2008). Antiinflammatory Actions of HDL. Arteriosclerosis, Thrombosis, and Vascular Biology, 28(11), 1890-1891. [More Information]
  • Tabet, F., Barter, P., Rye, K. (2008). Apolipoprotein A-I and Reconstituted High-Density Lipoproteins Inhibit NADPH Oxidase Activation and Expression and Increase Superoxide Dismutase Levels in Human Macrophages in High Glucose Conditions. Arteriosclerosis, Thrombosis, and Vascular Biology, 28(6), e-87.
  • Barter, P., Ginsberg, H. (2008). Effectiveness of Combined Statin Plus Omega-3 Fatty Acid Therapy for Mixed Dyslipidemia. American Journal of Cardiology, 102(8), 1040-1045. [More Information]

2007

  • Kastelein, J., Barter, P. (2007). A comparison of the association of on-treatment lipid and apolipoprotein parameters to cardiovascular events in ideal and TNT. Atherosclerosis Supplements, 8, 196.
  • Patel, S., Drew, B., Duffy, S., Nahkla, S., Rye, K., Barter, P., Celermajer, D., Kingwell, B. (2007). Abstract 1047: Infusion of Reconstituted High Density Lipoproteins Into Humans Enhances the In Vitro Anti-Inflammatory Capacity of the High Density Lipoprotein Fraction. Circulation, 116, II_209.
  • Scott, R., D'Emden, M., Best, J., Drury, P., Ehnholm, C., Kesaniemi, Y., Pardy, C., Tse, D., Barter, P., Taskinen, M., Copt, S., Keech, A., et al (2007). Abstract 3691: Features Of Metabolic Syndrome Identify Individuals With Type 2 Diabetes Mellitus At High Risk For Cardiovascular Events And Greater Absolute Benefits Of Fenofibrate. Circulation, 116, II_838.

2006

  • Puranik, R., Bao, B., Celermajer, D., Rye, K., Barter, P., Nicholls, S., Nobecourt, E. (2006). A single infusion of lipid free apo A1 can rescue vascular inflammation. Atherosclerosis Supplements, 7, 153.
  • Puranik, R., Nobecourt, E., Bao, B., Davies, M., Barter, P., Celermajer, D., Rye, K. (2006). Abstract 1355: The Impact of Glycation on the Anti-inflammatory Properties of High Density Lipoproteins in vivo. Circulation, 114, II-257-II-258.
  • Kastelein, J., Holme, I., Barter, P., Olsson, A., Cater, N., DeMicco, D., Gaffney, M., Szarek, M., LaRosa, J., Pedersen, T. (2006). Abstract 3357: Superiority of ApoB/ApoA1 Ratio for Predicting Cardiovascular Risk in Pooled Analyses of the Incremental Decrease in Endpoints through Aggressive Lipid-Lowering (IDEAL) and Treating to New Targets (TNT) Trials. Circulation, 114, II_713-II_714.

2005

  • Puranik, R., Barter, P. (2005). A single infusion of lipid free Apo A1 can rescue vascular inflammation, in vivo. Circulation, 112, U320.
  • Barter, P. (2005). Antiatherogenic Properties of Fibrates. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(6), 1095-1096. [More Information]
  • Barter, P. (2005). Cardioprotective Effects of High-Density Lipoproteins: The Evidence Strengthens. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(7), 1305-1306. [More Information]

2004

  • Barter, P., Nicholls, S., Rye, K., Anantharamaiah, G., Navab, M., Fogelman, A. (2004). Antiinflammatory Properties Of HDL. Circulation Research, 95(8), 764-772. [More Information]
  • Nicholls, S., Barter, P., Bao, B. (2004). Apolipoprotein composition influences the ability of reconstituted high density lipoproteins to promote a stable plaque phenotype. Circulation, 110, 37.
  • Hime, N., Drew, K., Hahn, C., Barter, P., Rye, K. (2004). Apolipoprotein E Enhances Hepatic Lipase-Mediated Hydrolysis Of Reconstituted High-Density Lipoprotein Phospholipid And Triacylglycerol In An Isoform-Dependent Manner. Biochemistry, 43(38), 12306-12314. [More Information]

2003

  • Rye, K., Wee, K., Curtiss, L., Bonnet, D., Barter, P. (2003). Apolipoprotein-A-II inhibits high density lipoprotein remodeling and lipid-poor apolipoprotein A-I formation. Journal of Biological Chemistry, 278(25), 22530-22536. [More Information]
  • Barter, P., Brewer, H., Chapman, M., Hennekens, C., Rader, D., Tall, A. (2003). Cholesteryl ester transfer protein. A novel target for raising HDL and inhibiting atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 23(2), 160-167. [More Information]
  • Duong, M., Psaltis, M., Rader, D., Marchadier, D., Barter, P., Rye, K. (2003). Evidence that hepatic lipase and endothelial lipase have different substrate specificities for high-density lipoprotein phospholipids. Biochemistry, 42(46), 13778-13785. [More Information]

2002

  • Rye, K., Duong, M., Psaltis, M., Curtiss, L., Bonnet, D., Stocker, R., Barter, P. (2002). Evidence that phospholipids play a key role in pre-β apoA-I formation and high density lipoprotein remodeling. Biochemistry, 41(41), 12538-12545. [More Information]

Selected Grants

2012

  • Atherosclerosis - the key roles of HDL, cell cholesterol metabolism and vascular function, Barter P, Celermajer D, Rye K, Kritharides L, Jessup W, National Health and Medical Research Council (NHMRC)/Program Grants

2007

  • Atherosclerosis: Lipoproteins, cell biology and vascular physiology, Barter P, Barter P, Celermajer D, National Health and Medical Research Council (NHMRC)/Program Grants