People_

Ms Rachel Teh

Postdoctoral Research Associate
Sydney Medical School
Westmead Clinical School
Faculty of Medicine and Health

Phone

02 8890 3739

Email

rachel.teh@sydney.edu.au

I am currently working on the proteomic analysis of pigmented lesions such as the common mole or nevi and melanoma. I hope to find differences in the protein content of these lesions in order to differentiate them from one another. Using archived formalin fixed parrafin embedded skin samples, I will collect the epidermis from patients that are between the ages of 18 to 65 from non-chronic sun exposed areas. The samples will be prepared through a protocol optimised by our lab and analysed using the Sequential Window Acquisition of all Theoretical Mass Spectra or SWATH MS workflow. The findings from this study will be used to investigate the potential for a non-invasive scarless biopsy for the early detection of melanoma.

Awards and honours

I am supported by the Australian Rotary of Health/Rotary Clubs of Chelsea, Mt Druitt and Mrs Val Henry PhD Scholarship and the University of Sydney

Themes

Cancer

Keywords

Biochemistry, Proteomics

Approaches

Translational Research

Publications

By Type

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Journals

Chan, S., Guitera, P., Ferguson, P., El Sharouni, M., Teh, R., Scolyer, R., Glanz, A. (2024). Predictors of malignancy in melanocytic lesions presenting as new lesions compared to baseline total body photography: A case-control study. Journal of the European Academy of Dermatology and Venereology. [More Information]
Teh, R., Azimi, A., Pupo, G., Ali, M., Mann, G., Fernandez Penas, P. (2023). Genomic and proteomic findings in early melanoma and opportunities for early diagnosis. Experimental Dermatology, 32(2), 104-116. [More Information]
Azimi, A., Patrick, E., Teh, R., Kim, J., Fernandez Penas, P. (2023). Proteomic profiling of cutaneous melanoma explains the aggressiveness of distant organ metastasis. Experimental Dermatology. [More Information]
Liu, C., Kim, Y., Teh, R., Garcia, A., Hamilton, E., Cornelius, F., Baxter, R., Rasmussen, H. (2022). Displacement of Native FXYD Protein From Na+/K+-ATPase With Novel FXYD Peptide Derivatives: Effects on Doxorubicin Cytotoxicity. Frontiers in Oncology, 12, 859216. [More Information]
Azimi, A., Teh, R., Fernandez Penas, P. (2021). Mass spectrometry-based proteomic analysis of the effect of storage temperature on non-invasively collected samples of human stratum corneum. Proteomics - Clinical Applications, 15(5), 2100005. [More Information]
Teh, R., Azimi, A., Ali, M., Mann, G., Fernandez Penas, P. (2021). Specialised skin cancer spectral library for use in data-independent mass spectrometry. Proteomics, 21(19), 2100128. [More Information]
Glastras, S., Chen, H., Tsang, M., Teh, R., McGrath, R., Zaky, A., Chen, J., Wong, M., Pollock, C., Saad, S. (2017). The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet. PloS One, 12(2), 1-17. [More Information]
Glastras, S., Tsang, M., Teh, R., Chen, H., McGrath, R., Zaky, A., Pollock, C., Saad, S. (2016). Maternal Obesity Promotes Diabetic Nephropathy in Rodent Offspring. Scientific Reports, 6, 1-9. [More Information]
Glastras, S., Chen, H., Teh, R., McGrath, R., Chen, J., Pollock, C., Wong, M., Saad, S. (2016). Mouse models of diabetes, obesity and related kidney disease. PloS One, 11(8), 1-15. [More Information]
Liu, C., Teh, R., Mozar, C., Baxter, R., Rasmussen, H. (2016). Silencing overexpression of FXYD3 protein in breast cancer cells amplifies effects of doxorubicin and y -radiation on Na+/K+-ATPase and cell survival. Breast Cancer Research and Treatment, 155(2), 203-213. [More Information]

show 7 more

By Year

Expand all

2024

Chan, S., Guitera, P., Ferguson, P., El Sharouni, M., Teh, R., Scolyer, R., Glanz, A. (2024). Predictors of malignancy in melanocytic lesions presenting as new lesions compared to baseline total body photography: A case-control study. Journal of the European Academy of Dermatology and Venereology. [More Information]

2023

Teh, R., Azimi, A., Pupo, G., Ali, M., Mann, G., Fernandez Penas, P. (2023). Genomic and proteomic findings in early melanoma and opportunities for early diagnosis. Experimental Dermatology, 32(2), 104-116. [More Information]
Azimi, A., Patrick, E., Teh, R., Kim, J., Fernandez Penas, P. (2023). Proteomic profiling of cutaneous melanoma explains the aggressiveness of distant organ metastasis. Experimental Dermatology. [More Information]

2022

Liu, C., Kim, Y., Teh, R., Garcia, A., Hamilton, E., Cornelius, F., Baxter, R., Rasmussen, H. (2022). Displacement of Native FXYD Protein From Na+/K+-ATPase With Novel FXYD Peptide Derivatives: Effects on Doxorubicin Cytotoxicity. Frontiers in Oncology, 12, 859216. [More Information]

2021

Azimi, A., Teh, R., Fernandez Penas, P. (2021). Mass spectrometry-based proteomic analysis of the effect of storage temperature on non-invasively collected samples of human stratum corneum. Proteomics - Clinical Applications, 15(5), 2100005. [More Information]
Teh, R., Azimi, A., Ali, M., Mann, G., Fernandez Penas, P. (2021). Specialised skin cancer spectral library for use in data-independent mass spectrometry. Proteomics, 21(19), 2100128. [More Information]

2017

Glastras, S., Chen, H., Tsang, M., Teh, R., McGrath, R., Zaky, A., Chen, J., Wong, M., Pollock, C., Saad, S. (2017). The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet. PloS One, 12(2), 1-17. [More Information]

2016

Glastras, S., Tsang, M., Teh, R., Chen, H., McGrath, R., Zaky, A., Pollock, C., Saad, S. (2016). Maternal Obesity Promotes Diabetic Nephropathy in Rodent Offspring. Scientific Reports, 6, 1-9. [More Information]
Glastras, S., Chen, H., Teh, R., McGrath, R., Chen, J., Pollock, C., Wong, M., Saad, S. (2016). Mouse models of diabetes, obesity and related kidney disease. PloS One, 11(8), 1-15. [More Information]
Liu, C., Teh, R., Mozar, C., Baxter, R., Rasmussen, H. (2016). Silencing overexpression of FXYD3 protein in breast cancer cells amplifies effects of doxorubicin and y -radiation on Na+/K+-ATPase and cell survival. Breast Cancer Research and Treatment, 155(2), 203-213. [More Information]

Selected Grants

2023