2024

• Khanppnavar, B., North, R., Ventura, S., Xu, Y. (2024). Advances, challenges, and opportunities in structural biology. Trends in Biochemical Sciences, 49(2), 93-96. [More Information]
• King-Hudson, T., North, R., Dobson, R., Davies, J., Quan, S., Currie, M., Tillett, Z., Copping, J., Panjikar, S., Friemann, R., et al (2024). On the function of TRAP substrate-binding proteins: Conformational variation of the sialic acid binding protein SiaP. Journal of Biological Chemistry, 300(11), 107851. [More Information]
• Currie, M., Davies, J., Scalise, M., Gulati, A., Wright, J., Newton-Vesty, M., Abeysekera, G., Subramanian, R., Wahlgren, W., Friemann, R., North, R., et al (2024). Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter. eLife, 13. [More Information]
• Davies, J., Currie, M., Dobson, R., Horne, C., North, R. (2024). TRAPs: the ‘elevator-with-an-operator’ mechanism. Trends in Biochemical Sciences, 49(2), 134-144. [More Information]

2023

• Davies, J., Currie, M., North, R., Scalise, M., Wright, J., Copping, J., Remus, D., Gulati, A., Morado, D., Jamieson, S. (2023). Structure and mechanism of the tripartite ATP-independent periplasmic (TRAP) transporter. Nature Communications, 14(1), 1120-1120. [More Information]

2021

• Horne, C., Venugopal, H., Panjikar, S., Wood, D., Henrickson, A., Brookes, E., North, R., Murphy, J., Friemann, R., Griffin, M. (2021). Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism. Nature Communications, 12(1), 1988-1988. [More Information]
• Currie, M., Manjunath, L., Horne, C., Rendle, P., Subramanian, R., Friemann, R., Fairbanks, A., Muscroft-Taylor, A., North, R., Dobson, R. (2021). N-Acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization. Journal of Biological Chemistry, 297(4), 101113-101113. [More Information]
• Davies, J., Currie, M., Wright, J., Newton-Vesty, M., North, R., Mace, P., Allison, J., Dobson, R. (2021). Selective Nutrient Transport in Bacteria: Multicomponent Transporter Systems Reign Supreme. Frontiers in Molecular Biosciences, 8, 699222-699222. [More Information]
• Drew, D., North, R., Nagarathinam, K., Tanabe, M. (2021). Structures and general transport mechanisms by the Major Facilitator Superfamily (MFS). Chemical Reviews, 121(9), 5289-5335. [More Information]
• Arif, T., Currie, M., Dobson, R., Newson, H., Poonthiyil, V., Fairbanks, A., North, R., Rendle, P. (2021). Synthesis of N-acetylmannosamine-6-phosphate derivatives to investigate the mechanism of N-acetylmannosamine-6-phosphate 2-epimerase. Carbohydrate Research, 510, 108445-108445. [More Information]

2020

• Adams, L., Rynkiewicz, P., Babbitt, G., Mortensen, J., North, R., Dobson, R., Hudson, A. (2020). Comparative molecular dynamics simulations provide insights into antibiotic effectiveness: a case study using the enzyme L,L-Diaminopimelate aminotransferase (DapL). Frontiers in Molecular Biosciences, 7, 46-46. [More Information]
• Coombes, D., Davies, J., Newton-Vesty, M., Horne, C., Setty, T., Subramanian, R., Moir, J., Friemann, R., Panjikar, S., North, R., et al (2020). The basis for non-canonical ROK family function in N-acetylmannosamine kinase from the pathogen Staphylococcus aureus. Journal of Biological Chemistry, 295(10), 3301-3315. [More Information]

2019

• Davies, J., Coombes, D., Horne, C., Pearce, F., Friemann, R., North, R., Dobson, R. (2019). Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus. FEBS Letters, 593(1), 52-66. [More Information]
• Crowther, J., Cross, P., Oliver, M., Leeman, M., Bartl, A., Weatherhead, A., North, R., Donovan, K., Griffin, M., Suzuki, H. (2019). Structure-function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control. Journal of Biological Chemistry, 294(21), 8505-8515. [More Information]

2018

• North, R., Horne, C., Davies, J., Remus, D., Muscroft-Taylor, A., Goyal, P., Wahlgren, W., Ramaswamy, S., Friemann, R., Dobson, R. (2018). "Just a spoonful of sugar..": import of sialic acid across bacterial cell membranes. Biophysical Reviews, 10(2), 219-227. [More Information]
• Manjunath, L., Guntupalli, S., Currie, M., North, R., Dobson, R., Nayak, V., Subramanian, R. (2018). Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 74(7), 431-440. [More Information]
• Wahlgren, W., Dunevall, E., North, R., Paz, A., Scalise, M., Bisignano, P., Bengtsson-Palme, J., Goyal, P., Claesson, E., Caing-Carlsson, R. (2018). Substrate-bound outward-open state of a Na+-coupled sialic acid symporter reveals a novel Na+ site. Nature Communications, 9(1), 1-14. [More Information]
• North, R., Wahlgren, W., Remus, D., Scalise, M., Kessans, S., Dunevall, E., Claesson, E., Soares da Costa, T., Perugini, M., Ramaswamy, S. (2018). The sodium sialic acid symporter from Staphylococcus aureus has altered substrate specificity. Frontiers in Chemistry, 6, 233-233. [More Information]

2017

• Caing-Carlsson, R., Goyal, P., Sharma, A., Ghosh, S., Setty, T., North, R., Friemann, R., Ramaswamy, G. (2017). Crystal structure of N-acetylmannosamine kinase from Fusobacterium nucleatum. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 73(6), 356-362. [More Information]

2016

• North, R., Watson, A., Pearce, F., Muscroft-Taylor, A., Friemann, R., Fairbanks, A., Dobson, R. (2016). Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Letters, 590(23), 4414-4428. [More Information]