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Professor Robert Sanders

BSc MBBS PhD DABA FRCA

Nuffield Chair of Anaesthetics
Sydney Medical School/Central Clinical School

robert.sanders@sydney.edu.au

Details

Member of the Brain and Mind Centre

Member of the Charles Perkins Centre

Prof Sanders, undertook a BSc in Neuroscience (First Class Honours) and trained in medicine at Imperial College London. Thereafter he completed specialist training in London in Anaesthetics. During much of that period he continued to perform basic neuroscience research in the laboratory of Prof Mervyn Maze. Spurred by those discoveries, he was awarded a Medical Research Council (UK) Clinical Training Fellowship funding his PhD in Biological Sciences (Imperial College London). He subsequently did a Postdoctoral fellowship at the Institute of Cognitive Neuroscience, Wellcome Department of Imaging Neuroscience, University College London and a Neuroanaesthesia fellowship at the National Hospital for Neurology and Neurosurgery, London. Having completed training, he moved to the University of Wisconsin, Madison, USA as an Assistant Professor. During his 5 years there, his research attracted more than $8 million AUD in NIH (USA) funding. In 2019, Dr. Sanders was awarded the Macintosh Professorship by the Royal College of Anaesthetists, UK. Prof Sanders then relocated to the University of Sydney in 2020 as the Nuffield Chair of Anaesthetics.

Research interests

My passion is translational medicine, understanding mechanisms of disease to improve patient outcomes and experience. Neuropsychiatric disorders, such as delirium, dementia and schizophrenia, have massive financial, personal and societal impact and also limited therapeutic options. My focus is innovative investigation into the underlying pathogenic mechanisms to identify novel therapeutics. We apply novel disease models inspired from theoretical neuroscience, and supported by empirical data, as a critical principle of our approach. The intent is to significantly disrupt fields that have failed produce therapies despite years of research.

My laboratory is also interested in the mechanisms of consciousness and, in particular, sensory perception. The critical purpose of anaesthesia (and sleep), is to become disconnected from the external world, yet the mechanisms of sensory disconnection and experience remain unclear. We aim to illuminate these mechanisms, not only in the name of scientific discovery, but also to yield new approaches to providing anaesthesia,

Teaching and supervision

Anaesthesia

Postoperatvie Cognitive Disorders

Mechanisms of consciousness and sensory disconnection

Current projects

Mechanisms of Postoperative Delirium

Mechanisms of Sensory Disconnection Under Anaesthesia

Awards and honours

2019 Macintosh Professor, Royal College of Anaesthetists

2013 Rising Star Lecture, Royal College of Anaesthetists

2008 GSK fellowship of the Royal Society of Medicine

2007 Royal Society of Medicine Anaesthesia Trainee Prize

2002 Goldberg–Schachmann Memorial prize

Publications

By Type

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Journals

Luney, M., Chalitsios, C., Lindsay, W., Sanders, R., McKeever, T., Moppett, I. (2024). Adverse outcomes after surgery after a cerebrovascular accident or acute coronary syndrome: a retrospective observational cohort study. British Journal of Anaesthesia. [More Information]
Taylor, J., Robledo, K., Medel, V., Heller, G., Payne, T., Wehrman, J., Casey, C., Yang, P., Krause, B., Lennertz, R., Naismith, S., Teixeira-Pinto, A., Sanders, R. (2024). Association between surgical admissions, cognition, and neurodegeneration in older people: a population-based study from the UK Biobank. The Lancet Healthy Longevity, 5(9), 100623. [More Information]
Staquet, C., Vanhaudenhuyse, A., Kandeepan, S., Sanders, R., Ribeiro De Paula, D., Brichant, J., Laureys, S., Bonhomme, V., Soddu, A. (2024). Changes in Intrinsic Connectivity Networks Topology Across Levels of Dexmedetomidine-Induced Alteration of Consciousness. Anesthesia and Analgesia, 139(4), 798-811. [More Information]
Gjini, K., Casey, C., Kunkel, D., Her, M., Banks, M., Pearce, R., Lennertz, R., Sanders, R. (2024). Delirium is associated with loss of feedback cortical connectivity. Alzheimer's and Dementia, 20(1), 511-524. [More Information]
Casey, C., Banks, M., Saalmann, Y., Pearce, R., Sanders, R., Tanabe, S., Farahbakhsh, Z., Parker, M., Bo, A., White, M., et al (2024). Evaluation of putative signatures of consciousness using specific definitions of responsiveness, connectedness, and consciousness. British Journal of Anaesthesia, 132(2), 300-311. [More Information]
McBride, K., Torzillo, J., Davis, R., Steffens, D., Wand, T., Sanders, R., Glozier, N., Solomon, M. (2024). Mental illness comorbidity significantly impacts surgical outcomes for emergency surgical patients. ANZ Journal of Surgery. [More Information]
Chalitsios, C., Luney, M., Lindsay, W., Sanders, R., McKeever, T., Moppett, I. (2024). Risk of Mortality Following Surgery in Patients With a Previous Cardiovascular Event. JAMA Surgery. [More Information]
Cecconi, B., Boly, M., Bahri, M., Lamalle, L., Laureys, S., Gosseries, O., Bonhomme, V., Annen, J., Montupil, J., Mortaheb, S., Sanders, R., et al (2024). Study protocol: Cerebral characterization of sensory gating in disconnected dreaming states during propofol anesthesia using fMRI. Frontiers in Neuroscience, 18, 1306344. [More Information]
Aldecoa, C., Forookhi, A., Gitti, N., Immonen, K., Kehlet, H., Koch, S., Kotfis, K., Latronico, N., MacLullich, A., Mevorach, L., Sanders, R., et al (2024). Update of the European Society of Anaesthesiology and Intensive Care Medicine evidence-based and consensus-based guideline on postoperative delirium in adult patients. European journal of Anaesthesiology, 41(2), 81-108. [More Information]
Duce, N., Bond, F., Sanders, R., Elliott, M., Downey, R. (2023). Association between perioperative hypertension and haematoma formation in neck dissection for head and neck cancer. Australian Journal of Otolaryngology, 6. [More Information]
Lennertz, R., Pryor, K., Raz, A., Parker, M., Bonhomme, V., Schuller, P., Schneider, G., Moore, M., Coburn, M., Root, J., Sanders, R., et al (2023). Connected consciousness after tracheal intubation in young adults: an international multicentre cohort study. British Journal of Anaesthesia, 130(2), e217-e224. [More Information]
Long, M., Sanders, R., Preiser, J. (2023). Critical Care and the Postintensive Care Syndrome. JAMA Network Open, 6(2), e230391. [More Information]
Payne, T., Braithwaite, H., Mcculloch, T., Paleologos, M., Johnstone, C., Wehrman, J., Taylor, J., Loadsman, J., Wang, A., Sanders, R. (2023). Depth of anaesthesia and mortality after cardiac or noncardiac surgery: a systematic review and meta-analysis of randomised controlled trials. British Journal of Anaesthesia, 130(2), e317-e329. [More Information]
Cardone, P., Bodart, O., Kirsch, M., Sanfilippo, J., Virgillito, A., Martial, C., Simon, J., Wannez, S., Sanders, R., Laureys, S., et al (2023). Depth of sedation with dexmedetomidine increases transcranial magnetic stimulation-evoked potential amplitude non-linearly. British Journal of Anaesthesia, 131(4), 715-725. [More Information]
Jufar, A., Sanders, R., Yao, S., Ortega-Bernal, V., Skene, A., Bellomo, R., Miles, L., Lankadeva, Y., May, C., Booth, L., et al (2023). Effects of dexmedetomidine on kidney and brain tissue microcirculation and histology in ovine cardiopulmonary bypass: a randomised controlled trial. Anaesthesia, 78(12), 1481-1492. [More Information]
Braithwaite, H., Sanders, R., Payne, T., Duce, N., Lim, J., Mcculloch, T., Loadsman, J., Leslie, K., Webster, A., Gaskell, A. (2023). Impact of female sex on anaesthetic awareness, depth, and emergence: a systematic review and meta-analysis. British Journal of Anaesthesia, 131(3), 510-522. [More Information]
Munn, B., Muller, E., Medel, V., Naismith, S., Lizier, J., Sanders, R., Shine, J. (2023). Neuronal connected burst cascades bridge macroscale adaptive signatures across arousal states. Nature Communications, 14(1). [More Information]
Taylor, J., Eisenmenger, L., Lindroth, H., Booth, J., Mohanty, R., Nair, V., Parker, M., Kunkel, D., Rivera, C., Casey, C., Sanders, R., et al (2023). Perioperative ischaemic brain injury and plasma neurofilament light: a secondary analysis of two prospective cohort studies. British Journal of Anaesthesia, 130(2), e361-e369. [More Information]
Perez, E., Mueller, R., Woodroffe, R., Ray, E., Gold, C., Park, B., Piscopo, A., Carnahan, R., Banks, M., Sanders, R., et al (2023). Postoperative Use of the Muscle Relaxants Baclofen and/or Cyclobenzaprine Associated with an Increased Risk of Delirium Following Lumbar Fusion. Spine, 48(24), 1733-1740. [More Information]
Payne, T., Taylor, J., Casey, C., Kunkel, D., Parker, M., Blennow, K., Zetterberg, H., Pearce, R., Lennertz, R., Sanders, R. (2023). Prospective analysis of plasma amyloid beta and postoperative delirium in the Interventions for Postoperative Delirium: Biomarker-3 study. British Journal of Anaesthesia, 130(5), 546-556. [More Information]
Taylor, J., Wu, J., Kunkel, D., Parker, M., Rivera, C., Casey, C., Naismith, S., Teixeira-Pinto, A., Maze, M., Pearce, R., Sanders, R., et al (2023). Resolution of elevated interleukin-6 after surgery is associated with return of normal cognitive function. British Journal of Anaesthesia, 131(4), 694-704. [More Information]
Taylor, J., Payne, T., Casey, C., Kunkel, D., Parker, M., Rivera, C., Zetterberg, H., Blennow, K., Pearce, R., Lennertz, R., McCulloch, T., Sanders, R., et al (2023). Sevoflurane dose and postoperative delirium: a prospective cohort analysis. British Journal of Anaesthesia, 130(2), e289-e297. [More Information]
Wehrman, J., Casey, C., Tanabe, S., Mohanta, S., Filbey, W., Weber, L., Banks, M., Pearce, R., Saalmann, Y., Sanders, R. (2023). Subanaesthetic doses of ketamine reduce but do not eliminate predictive coding responses: implications for mechanisms of sensory disconnection. British Journal of Anaesthesia, 131(4), 705-714. [More Information]
Hindman, B., Gold, C., Ray, E., Wendt, L., Ten Eyck, P., Berger, J., Olinger, C., Banks, M., Sanders, R., Howard, M., et al (2023). Surgeon-Specific Treatment Selection Bias and Heterogeneous Perioperative Practices in an Observational Spine Surgery Study. A Statistical Tutorial with Implications for Analysis of Observational Studies of Perioperative Interventions. World Neurosurgery. [More Information]
Payne, T., Coburn, M., Dieleman, S., Heller, G., Jardine, M., Shehabi, Y., Sanders, R. (2023). The impact of dexmedetomidine on postoperative delirium: should we throw out a DECADE of research? British Journal of Anaesthesia, 130(6), e479-e481. [More Information]
Wehrman, J., Sanders, R., Wearden, J. (2023). What came before: Assimilation effects in the categorization of time intervals. Cognition, 234. [More Information]
Torres-Velázquez, M., Parker, M., Bo, A., White, M., Tanabe, S., Pearce, R., Lennertz, R., Cho, S., Bendlin, B., Johnson, S., Sanders, R., et al (2022). Amyloid deposition on positron emission tomography correlates with severity of perioperative delirium: a case-control pilot study. British Journal of Anaesthesia, 128(3), e226-e228. [More Information]
Krause, B., Manning, H., Sabia, S., Singh-Manoux, A., Sanders, R. (2022). Association of Major Surgical Admissions with Quality of Life: 19-Year Follow-up of the Whitehall II Longitudinal Prospective Cohort Study. JAMA Surgery, 157(3), 275-277. [More Information]
Parker, M., White, M., Casey, C., Kunkel, D., Bo, A., Blennow, K., Zetterberg, H., Pearce, R., Lennertz, R., Sanders, R. (2022). Cohort Analysis of the Association of Delirium Severity with Cerebrospinal Fluid Amyloid-Tau-Neurodegeneration Pathologies. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 77(3), 494-501. [More Information]
Amlong, C., Rusy, D., Sanders, R., Wendell, L., Raz, A. (2022). Dexmedetomidine depresses neuronal activity in the subthalamic nucleus during deep brain stimulation electrode implantation surgery. BJA Open, 3, 100088. [More Information]
Casey, C., Tanabe, S., Farahbakhsh, Z., Parker, M., Bo, A., White, M., Ballweg, T., Mcintosh, A., Filbey, W., Saalmann, Y., Sanders, R., et al (2022). Distinct EEG signatures differentiate unconsciousness and disconnection during anaesthesia and sleep. British Journal of Anaesthesia, 128(6), 1006-1018. [More Information]
Casey, C., Tanabe, S., Farahbakhsh, Z., Parker, M., Bo, A., White, M., Ballweg, T., Mcintosh, A., Filbey, W., Banks, M., Sanders, R., et al (2022). Dynamic causal modelling of auditory surprise during disconnected consciousness: The role of feedback connectivity. NeuroImage, 263. [More Information]
Gjini, K., Casey, C., Tanabe, S., Bo, A., Parker, M., White, M., Kunkel, D., Lennertz, R., Pearce, R., Betthauser, T., Sanders, R., et al (2022). Greater tau pathology is associated with altered predictive coding. Brain Communications, 4(5). [More Information]
Kunkel, D., Parker, M., Casey, C., Krause, B., Taylor, J., Pearce, R., Lennertz, R., Sanders, R. (2022). Impact of perioperative inflammation on days alive and at home after surgery. BJA Open, 2, 100006. [More Information]
Page, V., Watne, L., Heslegrave, A., Clark, A., McAuley, D., Sanders, R., Zetterberg, H. (2022). Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients. EBioMedicine, 80. [More Information]
Taylor, J., Parker, M., Casey, C., Tanabe, S., Kunkel, D., Rivera, C., Zetterberg, H., Blennow, K., Pearce, R., Lennertz, R., Sanders, R. (2022). Postoperative delirium and changes in the blood–brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study. British Journal of Anaesthesia, 129(2), 219-230. [More Information]
Wang, S., Greene, R., Song, Y., Chan, C., Lindroth, H., Khan, S., Rios, G., Sanders, R., Khan, B. (2022). Postoperative delirium and its relationship with biomarkers for dementia: a meta-analysis. International Psychogeriatrics, 34(4), 377-390. [More Information]
Yang, X., Li, Z., Wang, B., Pan, Y., Jiang, C., Zhang, X., Yang, Y., Zhou, C., Hu, C., Zhang, Z., Sanders, R., et al (2022). Prognosis and antibody profiles in survivors of critical illness from COVID-19: a prospective multicentre cohort study. British Journal of Anaesthesia, 128(3), 491-500. [More Information]
Mashour, G., Sanders, R., Lee, U. (2022). Propofol Anesthesia: A Leap into the Void? Anesthesiology, 136(3), 405-407. [More Information]
Tanabe, S., Parker, M., Lennertz, R., Pearce, R., Banks, M., Sanders, R. (2022). Reduced Electroencephalogram Complexity in Postoperative Delirium. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 77(3), 502-506. [More Information]
Gold, C., Ray, E., Christianson, D., Park, B., Kournoutas, I., Kahn, T., Perez, E., Berger, J., Sander, K., Igram, C., Sanders, R., et al (2022). Risk factors for delirium in elderly patients after lumbar spinal fusion. Clinical Neurology and Neurosurgery, 219. [More Information]
Wu, J., Taylor, J., Parker, M., Kunkel, D., Rivera, C., Pearce, R., Lennertz, R., Sanders, R. (2022). Role of interleukin-18 in postoperative delirium: an exploratory analysis. British Journal of Anaesthesia, 128(3), e229-e231. [More Information]
Yung, A., Wong, G., Pillinger, N., Wykes, J., Haddad, R., McInnes, S., Palme, C., Low, T., Clark, J., Sanders, R., Ch'ng, S. (2022). Validation of a risk prediction calculator in Australian patients undergoing head and neck microsurgery reconstruction. Journal of Plastic, Reconstructive and Aesthetic Surgery, 75(9), 3323-3329. [More Information]
Ballweg, T., White, M., Parker, M., Casey, C., Bo, A., Farahbakhsh, Z., Kayser, A., Blair, A., Lindroth, H., Pearce, R., Sanders, R., et al (2021). Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study. British Journal of Anaesthesia, 126(2), 458-466. [More Information]
Hughes, C., Mailloux, P., Devlin, J., Swan, J., Sanders, R., Anzueto, A., Jackson, J., Hoskins, A., Pun, B., Orun, O., et al (2021). Dexmedetomidine or propofol for sedation in mechanically ventilated adults with sepsis. New England Journal of Medicine, 384(15), 1424-1436. [More Information]
Sultan, Z., Jaeckel, E., Krause, B., Grady, S., Murphy, C., Sanders, R., Banks, M. (2021). Electrophysiological signatures of acute systemic lipopolysaccharide-induced inflammation: potential implications for delirium science. British Journal of Anaesthesia, 126(5), 996-1008. [More Information]
Kunkel, D., Parker, M., Casey, C., Krause, B., Pearce, R., Lennertz, R., Sanders, R. (2021). Impact of postoperative delirium on days alive and at home after surgery: a prospective cohort study. British Journal of Anaesthesia, 127(6), e205-e207. [More Information]
Linassi, F., Obert, D., Maran, E., Tellaroli, P., Kreuzer, M., Sanders, R., Carron, M. (2021). Implicit memory and anesthesia: A systematic review and meta‐analysis. Life, 11(8). [More Information]
Sanders, R., Wehrman, J., Irons, J., Dieleman, J., Scott, D., Shehabi, Y. (2021). Meta-analysis of randomised controlled trials of perioperative dexmedetomidine to reduce delirium and mortality after cardiac surgery. British Journal of Anaesthesia, 127(5), e168-e170. [More Information]
Sanders, R., Craigova, L., Schessler, B., Casey, C., White, M., Parker, M., Kunkel, D., Blennow, K., Zetterberg, H., Pearce, R., et al (2021). Postoperative troponin increases after noncardiac surgery are associated with raised neurofilament light: a prospective observational cohort study. British Journal of Anaesthesia, 126(4), 791-798. [More Information]
Sanders, R., Casey, C., Saalmann, Y. (2021). Predictive coding as a model of sensory disconnection: relevance to anaesthetic mechanisms. British Journal of Anaesthesia, 126(15), 37-40. [More Information]
Mohanta, S., Afrasiabi, M., Casey, C., Tanabe, S., Redinbaugh, M., Kambi, N., Phillips, J., Polyakov, D., Filbey, W., Austerweil, J., et al (2021). Predictive Feedback, Early Sensory Representations, and Fast Responses to Predicted Stimuli Depend on NMDA Receptors. Journal of Neuroscience, 41(49), 10130-10147. [More Information]
White, M., Tanabe, S., Casey, C., Parker, M., Bo, A., Kunkel, D., Nair, V., Pearce, R., Lennertz, R., Prabhakaran, V., Sanders, R., et al (2021). Relationships between preoperative cortical thickness, postoperative electroencephalogram slowing, and postoperative delirium. British Journal of Anaesthesia, 127(2), 236-244. [More Information]
Chuan, A., Sanders, R. (2021). The use of dexmedetomidine to prevent delirium after major cardiac and non-cardiac surgery. Anaesthesia, 76(10), 1296-1299. [More Information]
Delp, S., Mei, W., Spies, C., Neuner, B., Aldecoa, C., Bettelli, G., Bilotta, F., Sanders, R., Kramer, S., Weiss, B. (2020). Clinical practice in the management of postoperative delirium by Chinese anesthesiologists: a cross-sectional survey designed by the European Society of Anaesthesiology. Journal of international medical research, 48(6). [More Information]
Tanabe, S., Mohanty, R., Lindroth, H., Casey, C., Ballweg, T., Farahbakhsh, Z., Krause, B., Prabhakaran, V., Banks, M., Sanders, R. (2020). Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity. British Journal of Anaesthesia, 125(1), 55-66. [More Information]
Tanabe, S., Bo, A., White, M., Parker, M., Farahbakhsh, Z., Ballweg, T., Casey, C., Betthauser, T., Zetterberg, H., et al, Sanders, R. (2020). Cohort study of electroencephalography markers of amyloid-tau-neurodegeneration pathology. Brain Communications, 2(2), fcaa099. [More Information]
Sanders, R. (2020). Does Delta Connectivity Differentiate Sleep and Anesthesia? Anesthesiology, 133(4), 700-701. [More Information]
Kozarek, K., Sanders, R., Head, D. (2020). Perioperative blood pressure in the elderly. Current Opinion in Anaesthesiology, 33(1), 122-127. [More Information]
Casey, C., Lindroth, H., Mohanty, R., Farahbakhsh, Z., Ballweg, T., Twadell, S., Miller, S., Krause, B., Prabhakaran, V., Blennow, K., et al (2020). Postoperative delirium is associated with increased plasma neurofilament light. Brain, 143(1), 47-54. [More Information]
Bilotta, F., Weiss, B., Neuner, B., Kramer, S., Aldecoa, C., Bettelli, G., Sanders, R., Delp, S., Spies, C. (2020). Routine management of postoperative delirium outside the ICU: Results of an international survey among anaesthesiologists. Acta Anaesthesiologica Scandinavica, 64(4), 494-500. [More Information]
Krause, B., Sabia, S., Manning, H., Singh-Manoux, A., Sanders, R. (2019). Association between major surgical admissions and the cognitive trajectory: 19 Year follow-up of Whitehall II cohort study. BMJ, 366, l4466. [More Information]
Lindroth, H., Nair, V., Stanfield, C., Casey, C., Mohanty, R., Wayer, D., Rowley, P., Brown, R., Prabhakaran, V., Sanders, R. (2019). Examining the identification of age-related atrophy between T1 and T1?+?T2-FLAIR cortical thickness measurements. Scientific Reports, 9(1), 11288. [More Information]
Mrkobrada, M., Chan, M., Cowan, D., Campbell, D., Wang, C., Torres, D., Malaga, G., Sanders, R., Sharma, M., Brown, C., et al (2019). Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study. The Lancet, 394(10203), 1022-1029. [More Information]
McEvoy, M., Gupta, R., Koepke, E., Feldheiser, A., Michard, F., Levett, D., Thacker, J., Hamilton, M., Grocott, M., Mythen, M., et al (2019). Perioperative Quality Initiative consensus statement on postoperative blood pressure, risk and outcomes for elective surgery. British Journal of Anaesthesia, 122(5), 575-586. [More Information]
Sanders, R., Hughes, F., Shaw, A., Thompson, A., Bader, A., Hoeft, A., Williams, D., Grocott, M., Mythen, M., Miller, T., et al (2019). Perioperative Quality Initiative consensus statement on preoperative blood pressure, risk and outcomes for elective surgery. British Journal of Anaesthesia, 122(5), 552-562. [More Information]
Ackland, G., Brudney, C., Cecconi, M., Ince, C., Irwin, M., Lacey, J., Pinsky, M., Grocott, M., Mythen, M., Edwards, M., et al (2019). Perioperative Quality Initiative consensus statement on the physiology of arterial blood pressure control in perioperative medicine. British Journal of Anaesthesia, 122(5), 542-551. [More Information]
Lindroth, H., Bratzke, L., Twadell, S., Rowley, P., Kildow, J., Danner, M., Turner, L., Hernandez, B., Brown, R., Sanders, R. (2019). Predicting postoperative delirium severity in older adults: The role of surgical risk and executive function. International Journal of Geriatric Psychiatry, 34(7), 1018-1028. [More Information]
Venkatesan, S., Jorgensen, M., Manning, H., Andersson, C., Mozid, A., Coburn, M., Moonesinghe, S., Foex, P., Mythen, M., Grocott, M., et al (2019). Preoperative chronic beta-blocker prescription in elderly patients as a risk factor for postoperative mortality stratified by preoperative blood pressure: a cohort study. British Journal of Anaesthesia, 123(2), 118-125. [More Information]
Andreasen, C., Jorgensen, M., Gislason, G., Martinsson, A., Sanders, R., Abdulla, J., Jensen, P., Torp-Pedersen, C., Kober, L., Andersson, C. (2018). Association of timing of aortic valve replacement surgery after stroke with risk of recurrent stroke and mortality. JAMA Cardiology, 3(6), 506-513. [More Information]
Jorgensen, M., Andersson, C., Venkatesan, S., Sanders, R. (2018). Beta-blockers in noncardiac surgery: Did observational studies put us back on safe ground? British Journal of Anaesthesia, 121(1), 16-25. [More Information]
Duan, X., Coburn, M., Rossaint, R., Sanders, R., Waesberghe, J., Kowark, A. (2018). Efficacy of perioperative dexmedetomidine on postoperative delirium: systematic review and meta-analysis with trial sequential analysis of randomised controlled trials. British Journal of Anaesthesia, 121(2), 384-397. [More Information]
Darracq, M., Funk, C., Polyakov, D., Riedner, B., Gosseries, O., Nieminen, J., Bonhomme, V., Brichant, J., Boly, M., Laureys, S., et al (2018). Evoked Alpha Power is Reduced in Disconnected Consciousness During Sleep and Anesthesia. Scientific Reports, 8(1), 16664. [More Information]
Kowark, A., Adam, C., Ahrens, J., Bajbouj, M., Bollheimer, C., Borowski, M., Dodel, R., Dolch, M., Hachenberg, T., Henzler, D., et al (2018). Improve hip fracture outcome in the elderly patient (iHOPE): A study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia. BMJ Open, 8(10), e023609. [More Information]
White, S., Altermatt, F., Barry, J., Ben-David, B., Coburn, M., Coluzzi, F., Degoli, M., Dillane, D., Foss, N., Gelmanas, A., et al (2018). International Fragility Fracture Network Delphi consensus statement on the principles of anaesthesia for patients with hip fracture. Anaesthesia, 73(7), 863-874. [More Information]
Sanders, R., Winston, J., Barnes, G., Rees, G. (2018). Magnetoencephalographic Correlates of Perceptual State during Auditory Bistability. Scientific Reports, 8(1), 976. [More Information]
Wang, C., Datoo, T., Zhao, H., Wu, L., Date, A., Jiang, C., Sanders, R., Wang, G., Bevan, C., Ma, D. (2018). Midazolam and dexmedetomidine affect neuroglioma and lung carcinoma cell biology in vitro and in vivo. Anesthesiology, 129(5), 1000-1014. [More Information]
Sanders, R., Banks, M., Darracq, M., Moran, R., Sleigh, J., Gosseries, O., Bonhomme, V., Brichant, J., Rosanova, M., Raz, A., et al (2018). Propofol-induced unresponsiveness is associated with impaired feedforward connectivity in cortical hierarchy. British Journal of Anaesthesia, 121(5), 1084-1096. [More Information]
Mrkobrada, M., Chan, M., Cowan, D., Spence, J., Campbell, D., Wang, C., Torres, D., Malaga, G., Sanders, R., Brown, C., et al (2018). Rationale and design for the detection and neurological impact of cerebrovascular events in non-cardiac surgery patients cohort evaluation (NeuroVISION) study: A prospective international cohort study. BMJ Open, 8(7), e021521. [More Information]
Lindroth, H., Bratzke, L., Purvis, S., Brown, R., Coburn, M., Mrkobrada, M., Chan, M., Davis, D., Pandharipande, P., Carlsson, C., et al (2018). Systematic review of prediction models for delirium in the older adult inpatient. BMJ Open, 8(4), e019223. [More Information]
Coburn, M., Sanders, R., Maze, M., Nguyen-Pascal, M., Rex, S., Garrigues, B., Carbonell, J., Garcia-Perez, M., Stevanovic, A., Kienbaum, P., et al (2018). The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial. British Journal of Anaesthesia, 120(1), 127-137. [More Information]
Jorgensen, M., Sanders, R., Kober, L., Mehta, K., Torp-Pedersen, C., Hlatky, M., Pallisgaard, J., Shaw, R., Gislason, G., Jensen, P., et al (2017). Beta-blocker subtype and risks of perioperative adverse events following non-cardiac surgery: A nationwide cohort study. European Heart Journal, 38(31), 2421-2428. [More Information]
Guldenmund, P., Vanhaudenhuyse, A., Sanders, R., Sleigh, J., Bruno, M., Demertzi, A., Bahri, M., Jaquet, O., Sanfilippo, J., Baquero, K., et al (2017). Brain functional connectivity differentiates dexmedetomidine from propofol and natural sleep. British Journal of Anaesthesia, 119(4), 674-684. [More Information]
Venkatesan, S., Myles, P., Manning, H., Mozid, A., Andersson, C., Jorgensen, M., Hardman, J., Moonesinghe, S., Foex, P., Mythen, M., et al (2017). Cohort study of preoperative blood pressure and risk of 30-day mortality after elective non-cardiac surgery. British Journal of Anaesthesia, 119(1), 65-77. [More Information]
Ezzati, M., Kawano, G., Rocha-Ferreira, E., Alonso-Alconada, D., Hassell, J., Broad, K., Fierens, I., Fleiss, B., Bainbridge, A., Price, D., et al (2017). Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia. Developmental Neuroscience, 39(1-4), 156-170. [More Information]
Aldecoa, C., Bettelli, G., Bilotta, F., Sanders, R., Audisio, R., Borozdina, A., Cherubini, A., Jones, C., Kehlet, H., Maclullich, A., et al (2017). European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium. European journal of Anaesthesiology, 34(4), 192-214. [More Information]
Gaskell, A., Hight, D., Winders, J., Tran, G., Defresne, A., Bonhomme, V., Raz, A., Sleigh, J., Sanders, R. (2017). Frontal alpha-delta EEG does not preclude volitional response during anaesthesia: Prospective cohort study of the isolated forearm technique. British Journal of Anaesthesia, 119(4), 664-673. [More Information]
Sanders, R., Gaskell, A., Raz, A., Winders, J., Stevanovic, A., Rossaint, R., Boncyk, C., Defresne, A., Tran, G., Tasbihgou, S., et al (2017). Incidence of Connected Consciousness after Tracheal Intubation: A Prospective, International, Multicenter Cohort Study of the Isolated Forearm Technique. Anesthesiology, 126(2), 214-222. [More Information]
Lee, M., Sanders, R., Yeom, S., Won, D., Seo, K., Kim, H., Tononi, G., Lee, S. (2017). Network Properties in Transitions of Consciousness during Propofol-induced Sedation. Scientific Reports, 7(1), 16791. [More Information]
Alam, A., Suen, K., Hana, Z., Sanders, R., Maze, M., Ma, D. (2017). Neuroprotection and neurotoxicity in the developing brain: an update on the effects of dexmedetomidine and xenon. Neurotoxicology and Teratology, 60, 102-116. [More Information]
Christiansen, M., Andersson, C., Gislason, G., Torp-Pedersen, C., Sanders, R., Foge Jensen, P., Jorgensen, M. (2017). Risks of Cardiovascular Adverse Events and Death in Patients with Previous Stroke Undergoing Emergency Noncardiac, Nonintracranial Surgery: The Importance of Operative Timing. Anesthesiology, 127(1), 9-19. [More Information]
Broad, K., Kawano, G., Fierens, I., Rocha-Ferreira, E., Hristova, M., Ezzati, M., Rostami, J., Alonso-Alconada, D., Chaban, B., Hassell, J., et al (2017). Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain. PloS One, 12(3), 173413. [More Information]
Coburn, M., Sanders, R., Neuman, M., Rossaint, R., Matot, I. (2017). We may have improved but we must get better still. European journal of Anaesthesiology, 34(3), 115-117. [More Information]
Roshanov, P., Rochwerg, B., Patel, A., Salehian, O., Duceppe, E., Belley-Cote, E., Guyatt, G., Sessler, D., Le Manach, Y., Borges, F., et al (2017). Withholding versus Continuing Angiotensin-converting Enzyme Inhibitors or Angiotensin II Receptor Blockers before Noncardiac Surgery. Anesthesiology, 126(1), 16-27. [More Information]
Devroe, S., Meeusen, R., Gewillig, M., Cools, B., Poesen, K., Sanders, R., Rex, S. (2017). Xenon as an adjuvant to sevoflurane anesthesia in children younger than 4 years of age, undergoing interventional or diagnostic cardiac catheterization: A randomized controlled clinical trial. Paediatric Anaesthesia, 27(12), 1210-1219. [More Information]
Venkatesan, S., Okoli, G., Mozid, A., Pickworth, T., Grocott, M., Sanders, R., Myles, P. (2016). Effects of five preoperative cardiovascular drugs on mortality after coronary artery bypab surgery. European journal of Anaesthesiology, 33(1), 49-57. [More Information]
Broad, K., Fierens, I., Fleiss, B., Rocha-Ferreira, E., Ezzati, M., Hassell, J., Alonso-Alconada, D., Bainbridge, A., Kawano, G., Ma, D., et al (2016). Inhaled 45-50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia. Neurobiology of Disease, 87, 29-38. [More Information]
Broad, K., Hassell, J., Fleiss, B., Kawano, G., Ezzati, M., Rocha-Ferreira, E., Hristova, M., Bennett, K., Fierens, I., Burnett, R., et al (2016). Isoflurane exposure induces cell death, microglial activation and modifies the expression of genes supporting neurodevelopment and cognitive function in the male newborn piglet brain. PloS One, 11(11), e0166784. [More Information]
Nakafero, G., Sanders, R., Nguyen-Van-Tam, J., Myles, P. (2016). The association between benzodiazepines and influenza-like illness-related pneumonia and mortality: a survival analysis using UK Primary Care data. Pharmacoepidemiology and Drug Safety, 25(11), 1263-1273. [More Information]
Jorgensen, M., Hlatky, M., Kober, L., Sanders, R., Torp-Pedersen, C., Gislason, G., Jensen, P., Andersson, C. (2015). ?-blocker-associated risks in patients with uncomplicated hypertension undergoing noncardiac surgery. JAMA Internal Medicine, 175(12), 1923-1931. [More Information]
Nakafero, G., Sanders, R., Nguyen-Van-Tam, J., Myles, P. (2015). Association between benzodiazepine use and exacerbations and mortality in patients with asthma: A matched case-control and survival analysis using the United Kingdom Clinical Practice Research Datalink. Pharmacoepidemiology and Drug Safety, 24(8), 793-802. [More Information]
Munter, N., Stevanovic, A., Rossaint, R., Stoppe, C., Sanders, R., Coburn, M. (2015). CONSORT item adherence in top ranked anaesthesiology journals in 2011: A retrospective analysis. European journal of Anaesthesiology, 32(2), 117-125. [More Information]
Sanders, R., Grover, V., Goulding, J., Godlee, A., Gurney, S., Snelgrove, R., Ma, D., Singh, S., Maze, M., Hussell, T. (2015). Immune cell expression of GABAA receptors and the effects of diazepam on influenza infection. Journal of Neuroimmunology, 282, 97-103. [More Information]
Hollig, A., Schug, A., Fahlenkamp, A., Rossaint, R., Coburn, M., Brucken, A., Fries, M., Kepp, O., Lemaire, M., Ma, D., et al (2014). Argon: Systematic review on neuro- and organoprotective properties of an “Inert” gas. International Journal of Molecular Sciences, 15(10), 18175-18196. [More Information]
Marchant, N., Sanders, R., Sleigh, J., Vanhaudenhuyse, A., Bruno, M., Brichant, J., Laureys, S., Bonhomme, V. (2014). How electroencephalography serves the anesthesiologist. Clinical EEG and Neuroscience, 45(1), 22-32. [More Information]
Sanders, R. (2014). How important is peri-operative hypertension? Anaesthesia, 69(9), 948-953. [More Information]
Frank, B., Fulton, R., Lees, K., Sanders, R., Alexandrov, A., Bath, P., Bluhmki, E., Bornstein, N., Claesson, L., Curram, J., et al (2014). Impact of benzodiazepines on functional outcome and occurrence of pneumonia in stroke: Evidence from VISTA. International Journal of Stroke, 9(7), 890-894. [More Information]
Nadelson, M., Sanders, R., Avidan, M. (2014). Perioperative cognitive trajectory in adults. British Journal of Anaesthesia, 112(3), 440-451. [More Information]
Ezzati, M., Broad, K., Kawano, G., Faulkner, S., Hassell, J., Fleiss, B., Gressens, P., Fierens, I., Rostami, J., Maze, M., et al (2014). Pharmacokinetics of dexmedetomidine combined with therapeutic hypothermia in a piglet asphyxia model. Acta Anaesthesiologica Scandinavica, 58(6), 733-742. [More Information]
Liu, J., Rossaint, R., Sanders, R., Coburn, M. (2014). Toxic and protective effects of inhaled anaesthetics on the developing animal brain systematic review and update of recent experimental work. European journal of Anaesthesiology, 31(12), 669-677. [More Information]
Ning, J., Mo, L., Zhao, H., Lu, K., Wang, L., Lai, X., Yang, B., Zhao, H., Sanders, R., Ma, D. (2014). Transient regional hypothermia applied to a traumatic limb attenuates distant lung injury following blast limb trauma. Critical Care Medicine, 42(1). [More Information]
Sanders, R., Godlee, A., Fujimori, T., Goulding, J., Xin, G., Salek-Ardakani, S., Snelgrove, R., Ma, D., Maze, M., Hussell, T. (2013). Benzodiazepine augmented ?-amino-butyric acid signaling increases mortality from pneumonia in mice. Critical Care Medicine, 41(7), 1627-1636. [More Information]
Boly, M., Sanders, R., Mashour, G., Laureys, S. (2013). Consciousness and responsiveness: Lessons from anaesthesia and the vegetative state. Current Opinion in Anaesthesiology, 26(4), 444-449. [More Information]
Sanders, R., Godlee, A., Goulding, J., Ma, D., Maze, M., Hussell, T. (2013). Parenteral fluids do not affect pulmonary immune responses to influenza or susceptibility to secondary bacterial pneumonia in mice. Influenza and Other Respiratory Viruses, 7(6), 895-899. [More Information]
Sanders, R., Nicholson, A., Lewis, S., Smith, A., Alderson, P. (2013). Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery. Cochrane Database of Systematic Reviews, 2013 (7). [More Information]
Bottle, A., Mozid, A., Grocott, H., Walters, M., Lees, K., Aylin, P., Sanders, R. (2013). Preoperative risk factors in 10 418 patients with prior myocardial infarction and 5241 patients with prior unstable angina undergoing elective coronary artery bypass graft surgery. British Journal of Anaesthesia, 111(3), 417-423. [More Information]
Bottle, A., Mozid, A., Grocott, H., Walters, M., Lees, K., Aylin, P., Sanders, R. (2013). Preoperative stroke and outcomes after coronary artery bypass graft surgery. Anesthesiology, 118(4), 885-893. [More Information]
Bottle, A., Sanders, R., Mozid, A., Aylin, P. (2013). Provider profiling models for acute coronary syndrome mortality using administrative data. International Journal of Cardiology, 168(1), 338-343. [More Information]
Sanders, R., Maze, M. (2013). Take Off, Landing, and Fly Anesthesia. PLoS Genetics, 9(9). [More Information]
Obiora, E., Hubbard, R., Sanders, R., Myles, P. (2013). The impact of benzodiazepines on occurrence of pneumonia and mortality from pneumonia: A nested case-control and survival analysis in a population-based cohort. Thorax, 68(2), 163-170. [More Information]
Frank, B., Fulton, R., Weimar, C., Lees, K., Sanders, R. (2013). Use of paracetamol in ischaemic stroke patients: Evidence from VISTA. Acta Neurologica Scandinavica, 128(3), 172-177. [More Information]

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2024

Luney, M., Chalitsios, C., Lindsay, W., Sanders, R., McKeever, T., Moppett, I. (2024). Adverse outcomes after surgery after a cerebrovascular accident or acute coronary syndrome: a retrospective observational cohort study. British Journal of Anaesthesia. [More Information]
Taylor, J., Robledo, K., Medel, V., Heller, G., Payne, T., Wehrman, J., Casey, C., Yang, P., Krause, B., Lennertz, R., Naismith, S., Teixeira-Pinto, A., Sanders, R. (2024). Association between surgical admissions, cognition, and neurodegeneration in older people: a population-based study from the UK Biobank. The Lancet Healthy Longevity, 5(9), 100623. [More Information]
Staquet, C., Vanhaudenhuyse, A., Kandeepan, S., Sanders, R., Ribeiro De Paula, D., Brichant, J., Laureys, S., Bonhomme, V., Soddu, A. (2024). Changes in Intrinsic Connectivity Networks Topology Across Levels of Dexmedetomidine-Induced Alteration of Consciousness. Anesthesia and Analgesia, 139(4), 798-811. [More Information]
Gjini, K., Casey, C., Kunkel, D., Her, M., Banks, M., Pearce, R., Lennertz, R., Sanders, R. (2024). Delirium is associated with loss of feedback cortical connectivity. Alzheimer's and Dementia, 20(1), 511-524. [More Information]
Casey, C., Banks, M., Saalmann, Y., Pearce, R., Sanders, R., Tanabe, S., Farahbakhsh, Z., Parker, M., Bo, A., White, M., et al (2024). Evaluation of putative signatures of consciousness using specific definitions of responsiveness, connectedness, and consciousness. British Journal of Anaesthesia, 132(2), 300-311. [More Information]
McBride, K., Torzillo, J., Davis, R., Steffens, D., Wand, T., Sanders, R., Glozier, N., Solomon, M. (2024). Mental illness comorbidity significantly impacts surgical outcomes for emergency surgical patients. ANZ Journal of Surgery. [More Information]
Chalitsios, C., Luney, M., Lindsay, W., Sanders, R., McKeever, T., Moppett, I. (2024). Risk of Mortality Following Surgery in Patients With a Previous Cardiovascular Event. JAMA Surgery. [More Information]
Cecconi, B., Boly, M., Bahri, M., Lamalle, L., Laureys, S., Gosseries, O., Bonhomme, V., Annen, J., Montupil, J., Mortaheb, S., Sanders, R., et al (2024). Study protocol: Cerebral characterization of sensory gating in disconnected dreaming states during propofol anesthesia using fMRI. Frontiers in Neuroscience, 18, 1306344. [More Information]
Aldecoa, C., Forookhi, A., Gitti, N., Immonen, K., Kehlet, H., Koch, S., Kotfis, K., Latronico, N., MacLullich, A., Mevorach, L., Sanders, R., et al (2024). Update of the European Society of Anaesthesiology and Intensive Care Medicine evidence-based and consensus-based guideline on postoperative delirium in adult patients. European journal of Anaesthesiology, 41(2), 81-108. [More Information]

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2023

Duce, N., Bond, F., Sanders, R., Elliott, M., Downey, R. (2023). Association between perioperative hypertension and haematoma formation in neck dissection for head and neck cancer. Australian Journal of Otolaryngology, 6. [More Information]
Lennertz, R., Pryor, K., Raz, A., Parker, M., Bonhomme, V., Schuller, P., Schneider, G., Moore, M., Coburn, M., Root, J., Sanders, R., et al (2023). Connected consciousness after tracheal intubation in young adults: an international multicentre cohort study. British Journal of Anaesthesia, 130(2), e217-e224. [More Information]
Long, M., Sanders, R., Preiser, J. (2023). Critical Care and the Postintensive Care Syndrome. JAMA Network Open, 6(2), e230391. [More Information]
Payne, T., Braithwaite, H., Mcculloch, T., Paleologos, M., Johnstone, C., Wehrman, J., Taylor, J., Loadsman, J., Wang, A., Sanders, R. (2023). Depth of anaesthesia and mortality after cardiac or noncardiac surgery: a systematic review and meta-analysis of randomised controlled trials. British Journal of Anaesthesia, 130(2), e317-e329. [More Information]
Cardone, P., Bodart, O., Kirsch, M., Sanfilippo, J., Virgillito, A., Martial, C., Simon, J., Wannez, S., Sanders, R., Laureys, S., et al (2023). Depth of sedation with dexmedetomidine increases transcranial magnetic stimulation-evoked potential amplitude non-linearly. British Journal of Anaesthesia, 131(4), 715-725. [More Information]
Jufar, A., Sanders, R., Yao, S., Ortega-Bernal, V., Skene, A., Bellomo, R., Miles, L., Lankadeva, Y., May, C., Booth, L., et al (2023). Effects of dexmedetomidine on kidney and brain tissue microcirculation and histology in ovine cardiopulmonary bypass: a randomised controlled trial. Anaesthesia, 78(12), 1481-1492. [More Information]
Braithwaite, H., Sanders, R., Payne, T., Duce, N., Lim, J., Mcculloch, T., Loadsman, J., Leslie, K., Webster, A., Gaskell, A. (2023). Impact of female sex on anaesthetic awareness, depth, and emergence: a systematic review and meta-analysis. British Journal of Anaesthesia, 131(3), 510-522. [More Information]
Munn, B., Muller, E., Medel, V., Naismith, S., Lizier, J., Sanders, R., Shine, J. (2023). Neuronal connected burst cascades bridge macroscale adaptive signatures across arousal states. Nature Communications, 14(1). [More Information]
Taylor, J., Eisenmenger, L., Lindroth, H., Booth, J., Mohanty, R., Nair, V., Parker, M., Kunkel, D., Rivera, C., Casey, C., Sanders, R., et al (2023). Perioperative ischaemic brain injury and plasma neurofilament light: a secondary analysis of two prospective cohort studies. British Journal of Anaesthesia, 130(2), e361-e369. [More Information]
Perez, E., Mueller, R., Woodroffe, R., Ray, E., Gold, C., Park, B., Piscopo, A., Carnahan, R., Banks, M., Sanders, R., et al (2023). Postoperative Use of the Muscle Relaxants Baclofen and/or Cyclobenzaprine Associated with an Increased Risk of Delirium Following Lumbar Fusion. Spine, 48(24), 1733-1740. [More Information]
Payne, T., Taylor, J., Casey, C., Kunkel, D., Parker, M., Blennow, K., Zetterberg, H., Pearce, R., Lennertz, R., Sanders, R. (2023). Prospective analysis of plasma amyloid beta and postoperative delirium in the Interventions for Postoperative Delirium: Biomarker-3 study. British Journal of Anaesthesia, 130(5), 546-556. [More Information]
Taylor, J., Wu, J., Kunkel, D., Parker, M., Rivera, C., Casey, C., Naismith, S., Teixeira-Pinto, A., Maze, M., Pearce, R., Sanders, R., et al (2023). Resolution of elevated interleukin-6 after surgery is associated with return of normal cognitive function. British Journal of Anaesthesia, 131(4), 694-704. [More Information]
Taylor, J., Payne, T., Casey, C., Kunkel, D., Parker, M., Rivera, C., Zetterberg, H., Blennow, K., Pearce, R., Lennertz, R., McCulloch, T., Sanders, R., et al (2023). Sevoflurane dose and postoperative delirium: a prospective cohort analysis. British Journal of Anaesthesia, 130(2), e289-e297. [More Information]
Wehrman, J., Casey, C., Tanabe, S., Mohanta, S., Filbey, W., Weber, L., Banks, M., Pearce, R., Saalmann, Y., Sanders, R. (2023). Subanaesthetic doses of ketamine reduce but do not eliminate predictive coding responses: implications for mechanisms of sensory disconnection. British Journal of Anaesthesia, 131(4), 705-714. [More Information]
Hindman, B., Gold, C., Ray, E., Wendt, L., Ten Eyck, P., Berger, J., Olinger, C., Banks, M., Sanders, R., Howard, M., et al (2023). Surgeon-Specific Treatment Selection Bias and Heterogeneous Perioperative Practices in an Observational Spine Surgery Study. A Statistical Tutorial with Implications for Analysis of Observational Studies of Perioperative Interventions. World Neurosurgery. [More Information]
Payne, T., Coburn, M., Dieleman, S., Heller, G., Jardine, M., Shehabi, Y., Sanders, R. (2023). The impact of dexmedetomidine on postoperative delirium: should we throw out a DECADE of research? British Journal of Anaesthesia, 130(6), e479-e481. [More Information]
Wehrman, J., Sanders, R., Wearden, J. (2023). What came before: Assimilation effects in the categorization of time intervals. Cognition, 234. [More Information]

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2022

Torres-Velázquez, M., Parker, M., Bo, A., White, M., Tanabe, S., Pearce, R., Lennertz, R., Cho, S., Bendlin, B., Johnson, S., Sanders, R., et al (2022). Amyloid deposition on positron emission tomography correlates with severity of perioperative delirium: a case-control pilot study. British Journal of Anaesthesia, 128(3), e226-e228. [More Information]
Krause, B., Manning, H., Sabia, S., Singh-Manoux, A., Sanders, R. (2022). Association of Major Surgical Admissions with Quality of Life: 19-Year Follow-up of the Whitehall II Longitudinal Prospective Cohort Study. JAMA Surgery, 157(3), 275-277. [More Information]
Parker, M., White, M., Casey, C., Kunkel, D., Bo, A., Blennow, K., Zetterberg, H., Pearce, R., Lennertz, R., Sanders, R. (2022). Cohort Analysis of the Association of Delirium Severity with Cerebrospinal Fluid Amyloid-Tau-Neurodegeneration Pathologies. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 77(3), 494-501. [More Information]
Amlong, C., Rusy, D., Sanders, R., Wendell, L., Raz, A. (2022). Dexmedetomidine depresses neuronal activity in the subthalamic nucleus during deep brain stimulation electrode implantation surgery. BJA Open, 3, 100088. [More Information]
Casey, C., Tanabe, S., Farahbakhsh, Z., Parker, M., Bo, A., White, M., Ballweg, T., Mcintosh, A., Filbey, W., Saalmann, Y., Sanders, R., et al (2022). Distinct EEG signatures differentiate unconsciousness and disconnection during anaesthesia and sleep. British Journal of Anaesthesia, 128(6), 1006-1018. [More Information]
Casey, C., Tanabe, S., Farahbakhsh, Z., Parker, M., Bo, A., White, M., Ballweg, T., Mcintosh, A., Filbey, W., Banks, M., Sanders, R., et al (2022). Dynamic causal modelling of auditory surprise during disconnected consciousness: The role of feedback connectivity. NeuroImage, 263. [More Information]
Gjini, K., Casey, C., Tanabe, S., Bo, A., Parker, M., White, M., Kunkel, D., Lennertz, R., Pearce, R., Betthauser, T., Sanders, R., et al (2022). Greater tau pathology is associated with altered predictive coding. Brain Communications, 4(5). [More Information]
Kunkel, D., Parker, M., Casey, C., Krause, B., Taylor, J., Pearce, R., Lennertz, R., Sanders, R. (2022). Impact of perioperative inflammation on days alive and at home after surgery. BJA Open, 2, 100006. [More Information]
Page, V., Watne, L., Heslegrave, A., Clark, A., McAuley, D., Sanders, R., Zetterberg, H. (2022). Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients. EBioMedicine, 80. [More Information]
Taylor, J., Parker, M., Casey, C., Tanabe, S., Kunkel, D., Rivera, C., Zetterberg, H., Blennow, K., Pearce, R., Lennertz, R., Sanders, R. (2022). Postoperative delirium and changes in the blood–brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study. British Journal of Anaesthesia, 129(2), 219-230. [More Information]
Wang, S., Greene, R., Song, Y., Chan, C., Lindroth, H., Khan, S., Rios, G., Sanders, R., Khan, B. (2022). Postoperative delirium and its relationship with biomarkers for dementia: a meta-analysis. International Psychogeriatrics, 34(4), 377-390. [More Information]
Yang, X., Li, Z., Wang, B., Pan, Y., Jiang, C., Zhang, X., Yang, Y., Zhou, C., Hu, C., Zhang, Z., Sanders, R., et al (2022). Prognosis and antibody profiles in survivors of critical illness from COVID-19: a prospective multicentre cohort study. British Journal of Anaesthesia, 128(3), 491-500. [More Information]
Mashour, G., Sanders, R., Lee, U. (2022). Propofol Anesthesia: A Leap into the Void? Anesthesiology, 136(3), 405-407. [More Information]
Tanabe, S., Parker, M., Lennertz, R., Pearce, R., Banks, M., Sanders, R. (2022). Reduced Electroencephalogram Complexity in Postoperative Delirium. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 77(3), 502-506. [More Information]
Gold, C., Ray, E., Christianson, D., Park, B., Kournoutas, I., Kahn, T., Perez, E., Berger, J., Sander, K., Igram, C., Sanders, R., et al (2022). Risk factors for delirium in elderly patients after lumbar spinal fusion. Clinical Neurology and Neurosurgery, 219. [More Information]
Wu, J., Taylor, J., Parker, M., Kunkel, D., Rivera, C., Pearce, R., Lennertz, R., Sanders, R. (2022). Role of interleukin-18 in postoperative delirium: an exploratory analysis. British Journal of Anaesthesia, 128(3), e229-e231. [More Information]
Yung, A., Wong, G., Pillinger, N., Wykes, J., Haddad, R., McInnes, S., Palme, C., Low, T., Clark, J., Sanders, R., Ch'ng, S. (2022). Validation of a risk prediction calculator in Australian patients undergoing head and neck microsurgery reconstruction. Journal of Plastic, Reconstructive and Aesthetic Surgery, 75(9), 3323-3329. [More Information]

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2021

Ballweg, T., White, M., Parker, M., Casey, C., Bo, A., Farahbakhsh, Z., Kayser, A., Blair, A., Lindroth, H., Pearce, R., Sanders, R., et al (2021). Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study. British Journal of Anaesthesia, 126(2), 458-466. [More Information]
Hughes, C., Mailloux, P., Devlin, J., Swan, J., Sanders, R., Anzueto, A., Jackson, J., Hoskins, A., Pun, B., Orun, O., et al (2021). Dexmedetomidine or propofol for sedation in mechanically ventilated adults with sepsis. New England Journal of Medicine, 384(15), 1424-1436. [More Information]
Sultan, Z., Jaeckel, E., Krause, B., Grady, S., Murphy, C., Sanders, R., Banks, M. (2021). Electrophysiological signatures of acute systemic lipopolysaccharide-induced inflammation: potential implications for delirium science. British Journal of Anaesthesia, 126(5), 996-1008. [More Information]
Kunkel, D., Parker, M., Casey, C., Krause, B., Pearce, R., Lennertz, R., Sanders, R. (2021). Impact of postoperative delirium on days alive and at home after surgery: a prospective cohort study. British Journal of Anaesthesia, 127(6), e205-e207. [More Information]
Linassi, F., Obert, D., Maran, E., Tellaroli, P., Kreuzer, M., Sanders, R., Carron, M. (2021). Implicit memory and anesthesia: A systematic review and meta‐analysis. Life, 11(8). [More Information]
Sanders, R., Wehrman, J., Irons, J., Dieleman, J., Scott, D., Shehabi, Y. (2021). Meta-analysis of randomised controlled trials of perioperative dexmedetomidine to reduce delirium and mortality after cardiac surgery. British Journal of Anaesthesia, 127(5), e168-e170. [More Information]
Sanders, R., Craigova, L., Schessler, B., Casey, C., White, M., Parker, M., Kunkel, D., Blennow, K., Zetterberg, H., Pearce, R., et al (2021). Postoperative troponin increases after noncardiac surgery are associated with raised neurofilament light: a prospective observational cohort study. British Journal of Anaesthesia, 126(4), 791-798. [More Information]
Sanders, R., Casey, C., Saalmann, Y. (2021). Predictive coding as a model of sensory disconnection: relevance to anaesthetic mechanisms. British Journal of Anaesthesia, 126(15), 37-40. [More Information]
Mohanta, S., Afrasiabi, M., Casey, C., Tanabe, S., Redinbaugh, M., Kambi, N., Phillips, J., Polyakov, D., Filbey, W., Austerweil, J., et al (2021). Predictive Feedback, Early Sensory Representations, and Fast Responses to Predicted Stimuli Depend on NMDA Receptors. Journal of Neuroscience, 41(49), 10130-10147. [More Information]
White, M., Tanabe, S., Casey, C., Parker, M., Bo, A., Kunkel, D., Nair, V., Pearce, R., Lennertz, R., Prabhakaran, V., Sanders, R., et al (2021). Relationships between preoperative cortical thickness, postoperative electroencephalogram slowing, and postoperative delirium. British Journal of Anaesthesia, 127(2), 236-244. [More Information]
Chuan, A., Sanders, R. (2021). The use of dexmedetomidine to prevent delirium after major cardiac and non-cardiac surgery. Anaesthesia, 76(10), 1296-1299. [More Information]

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2020

Delp, S., Mei, W., Spies, C., Neuner, B., Aldecoa, C., Bettelli, G., Bilotta, F., Sanders, R., Kramer, S., Weiss, B. (2020). Clinical practice in the management of postoperative delirium by Chinese anesthesiologists: a cross-sectional survey designed by the European Society of Anaesthesiology. Journal of international medical research, 48(6). [More Information]
Tanabe, S., Mohanty, R., Lindroth, H., Casey, C., Ballweg, T., Farahbakhsh, Z., Krause, B., Prabhakaran, V., Banks, M., Sanders, R. (2020). Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity. British Journal of Anaesthesia, 125(1), 55-66. [More Information]
Tanabe, S., Bo, A., White, M., Parker, M., Farahbakhsh, Z., Ballweg, T., Casey, C., Betthauser, T., Zetterberg, H., et al, Sanders, R. (2020). Cohort study of electroencephalography markers of amyloid-tau-neurodegeneration pathology. Brain Communications, 2(2), fcaa099. [More Information]
Sanders, R. (2020). Does Delta Connectivity Differentiate Sleep and Anesthesia? Anesthesiology, 133(4), 700-701. [More Information]
Kozarek, K., Sanders, R., Head, D. (2020). Perioperative blood pressure in the elderly. Current Opinion in Anaesthesiology, 33(1), 122-127. [More Information]
Casey, C., Lindroth, H., Mohanty, R., Farahbakhsh, Z., Ballweg, T., Twadell, S., Miller, S., Krause, B., Prabhakaran, V., Blennow, K., et al (2020). Postoperative delirium is associated with increased plasma neurofilament light. Brain, 143(1), 47-54. [More Information]
Bilotta, F., Weiss, B., Neuner, B., Kramer, S., Aldecoa, C., Bettelli, G., Sanders, R., Delp, S., Spies, C. (2020). Routine management of postoperative delirium outside the ICU: Results of an international survey among anaesthesiologists. Acta Anaesthesiologica Scandinavica, 64(4), 494-500. [More Information]

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2019

Krause, B., Sabia, S., Manning, H., Singh-Manoux, A., Sanders, R. (2019). Association between major surgical admissions and the cognitive trajectory: 19 Year follow-up of Whitehall II cohort study. BMJ, 366, l4466. [More Information]
Lindroth, H., Nair, V., Stanfield, C., Casey, C., Mohanty, R., Wayer, D., Rowley, P., Brown, R., Prabhakaran, V., Sanders, R. (2019). Examining the identification of age-related atrophy between T1 and T1?+?T2-FLAIR cortical thickness measurements. Scientific Reports, 9(1), 11288. [More Information]
Mrkobrada, M., Chan, M., Cowan, D., Campbell, D., Wang, C., Torres, D., Malaga, G., Sanders, R., Sharma, M., Brown, C., et al (2019). Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study. The Lancet, 394(10203), 1022-1029. [More Information]
McEvoy, M., Gupta, R., Koepke, E., Feldheiser, A., Michard, F., Levett, D., Thacker, J., Hamilton, M., Grocott, M., Mythen, M., et al (2019). Perioperative Quality Initiative consensus statement on postoperative blood pressure, risk and outcomes for elective surgery. British Journal of Anaesthesia, 122(5), 575-586. [More Information]
Sanders, R., Hughes, F., Shaw, A., Thompson, A., Bader, A., Hoeft, A., Williams, D., Grocott, M., Mythen, M., Miller, T., et al (2019). Perioperative Quality Initiative consensus statement on preoperative blood pressure, risk and outcomes for elective surgery. British Journal of Anaesthesia, 122(5), 552-562. [More Information]
Ackland, G., Brudney, C., Cecconi, M., Ince, C., Irwin, M., Lacey, J., Pinsky, M., Grocott, M., Mythen, M., Edwards, M., et al (2019). Perioperative Quality Initiative consensus statement on the physiology of arterial blood pressure control in perioperative medicine. British Journal of Anaesthesia, 122(5), 542-551. [More Information]
Lindroth, H., Bratzke, L., Twadell, S., Rowley, P., Kildow, J., Danner, M., Turner, L., Hernandez, B., Brown, R., Sanders, R. (2019). Predicting postoperative delirium severity in older adults: The role of surgical risk and executive function. International Journal of Geriatric Psychiatry, 34(7), 1018-1028. [More Information]
Venkatesan, S., Jorgensen, M., Manning, H., Andersson, C., Mozid, A., Coburn, M., Moonesinghe, S., Foex, P., Mythen, M., Grocott, M., et al (2019). Preoperative chronic beta-blocker prescription in elderly patients as a risk factor for postoperative mortality stratified by preoperative blood pressure: a cohort study. British Journal of Anaesthesia, 123(2), 118-125. [More Information]

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2018

Andreasen, C., Jorgensen, M., Gislason, G., Martinsson, A., Sanders, R., Abdulla, J., Jensen, P., Torp-Pedersen, C., Kober, L., Andersson, C. (2018). Association of timing of aortic valve replacement surgery after stroke with risk of recurrent stroke and mortality. JAMA Cardiology, 3(6), 506-513. [More Information]
Jorgensen, M., Andersson, C., Venkatesan, S., Sanders, R. (2018). Beta-blockers in noncardiac surgery: Did observational studies put us back on safe ground? British Journal of Anaesthesia, 121(1), 16-25. [More Information]
Duan, X., Coburn, M., Rossaint, R., Sanders, R., Waesberghe, J., Kowark, A. (2018). Efficacy of perioperative dexmedetomidine on postoperative delirium: systematic review and meta-analysis with trial sequential analysis of randomised controlled trials. British Journal of Anaesthesia, 121(2), 384-397. [More Information]
Darracq, M., Funk, C., Polyakov, D., Riedner, B., Gosseries, O., Nieminen, J., Bonhomme, V., Brichant, J., Boly, M., Laureys, S., et al (2018). Evoked Alpha Power is Reduced in Disconnected Consciousness During Sleep and Anesthesia. Scientific Reports, 8(1), 16664. [More Information]
Kowark, A., Adam, C., Ahrens, J., Bajbouj, M., Bollheimer, C., Borowski, M., Dodel, R., Dolch, M., Hachenberg, T., Henzler, D., et al (2018). Improve hip fracture outcome in the elderly patient (iHOPE): A study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia. BMJ Open, 8(10), e023609. [More Information]
White, S., Altermatt, F., Barry, J., Ben-David, B., Coburn, M., Coluzzi, F., Degoli, M., Dillane, D., Foss, N., Gelmanas, A., et al (2018). International Fragility Fracture Network Delphi consensus statement on the principles of anaesthesia for patients with hip fracture. Anaesthesia, 73(7), 863-874. [More Information]
Sanders, R., Winston, J., Barnes, G., Rees, G. (2018). Magnetoencephalographic Correlates of Perceptual State during Auditory Bistability. Scientific Reports, 8(1), 976. [More Information]
Wang, C., Datoo, T., Zhao, H., Wu, L., Date, A., Jiang, C., Sanders, R., Wang, G., Bevan, C., Ma, D. (2018). Midazolam and dexmedetomidine affect neuroglioma and lung carcinoma cell biology in vitro and in vivo. Anesthesiology, 129(5), 1000-1014. [More Information]
Sanders, R., Banks, M., Darracq, M., Moran, R., Sleigh, J., Gosseries, O., Bonhomme, V., Brichant, J., Rosanova, M., Raz, A., et al (2018). Propofol-induced unresponsiveness is associated with impaired feedforward connectivity in cortical hierarchy. British Journal of Anaesthesia, 121(5), 1084-1096. [More Information]
Mrkobrada, M., Chan, M., Cowan, D., Spence, J., Campbell, D., Wang, C., Torres, D., Malaga, G., Sanders, R., Brown, C., et al (2018). Rationale and design for the detection and neurological impact of cerebrovascular events in non-cardiac surgery patients cohort evaluation (NeuroVISION) study: A prospective international cohort study. BMJ Open, 8(7), e021521. [More Information]
Lindroth, H., Bratzke, L., Purvis, S., Brown, R., Coburn, M., Mrkobrada, M., Chan, M., Davis, D., Pandharipande, P., Carlsson, C., et al (2018). Systematic review of prediction models for delirium in the older adult inpatient. BMJ Open, 8(4), e019223. [More Information]
Coburn, M., Sanders, R., Maze, M., Nguyen-Pascal, M., Rex, S., Garrigues, B., Carbonell, J., Garcia-Perez, M., Stevanovic, A., Kienbaum, P., et al (2018). The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial. British Journal of Anaesthesia, 120(1), 127-137. [More Information]

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2017

Jorgensen, M., Sanders, R., Kober, L., Mehta, K., Torp-Pedersen, C., Hlatky, M., Pallisgaard, J., Shaw, R., Gislason, G., Jensen, P., et al (2017). Beta-blocker subtype and risks of perioperative adverse events following non-cardiac surgery: A nationwide cohort study. European Heart Journal, 38(31), 2421-2428. [More Information]
Guldenmund, P., Vanhaudenhuyse, A., Sanders, R., Sleigh, J., Bruno, M., Demertzi, A., Bahri, M., Jaquet, O., Sanfilippo, J., Baquero, K., et al (2017). Brain functional connectivity differentiates dexmedetomidine from propofol and natural sleep. British Journal of Anaesthesia, 119(4), 674-684. [More Information]
Venkatesan, S., Myles, P., Manning, H., Mozid, A., Andersson, C., Jorgensen, M., Hardman, J., Moonesinghe, S., Foex, P., Mythen, M., et al (2017). Cohort study of preoperative blood pressure and risk of 30-day mortality after elective non-cardiac surgery. British Journal of Anaesthesia, 119(1), 65-77. [More Information]
Ezzati, M., Kawano, G., Rocha-Ferreira, E., Alonso-Alconada, D., Hassell, J., Broad, K., Fierens, I., Fleiss, B., Bainbridge, A., Price, D., et al (2017). Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia. Developmental Neuroscience, 39(1-4), 156-170. [More Information]
Aldecoa, C., Bettelli, G., Bilotta, F., Sanders, R., Audisio, R., Borozdina, A., Cherubini, A., Jones, C., Kehlet, H., Maclullich, A., et al (2017). European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium. European journal of Anaesthesiology, 34(4), 192-214. [More Information]
Gaskell, A., Hight, D., Winders, J., Tran, G., Defresne, A., Bonhomme, V., Raz, A., Sleigh, J., Sanders, R. (2017). Frontal alpha-delta EEG does not preclude volitional response during anaesthesia: Prospective cohort study of the isolated forearm technique. British Journal of Anaesthesia, 119(4), 664-673. [More Information]
Sanders, R., Gaskell, A., Raz, A., Winders, J., Stevanovic, A., Rossaint, R., Boncyk, C., Defresne, A., Tran, G., Tasbihgou, S., et al (2017). Incidence of Connected Consciousness after Tracheal Intubation: A Prospective, International, Multicenter Cohort Study of the Isolated Forearm Technique. Anesthesiology, 126(2), 214-222. [More Information]
Lee, M., Sanders, R., Yeom, S., Won, D., Seo, K., Kim, H., Tononi, G., Lee, S. (2017). Network Properties in Transitions of Consciousness during Propofol-induced Sedation. Scientific Reports, 7(1), 16791. [More Information]
Alam, A., Suen, K., Hana, Z., Sanders, R., Maze, M., Ma, D. (2017). Neuroprotection and neurotoxicity in the developing brain: an update on the effects of dexmedetomidine and xenon. Neurotoxicology and Teratology, 60, 102-116. [More Information]
Christiansen, M., Andersson, C., Gislason, G., Torp-Pedersen, C., Sanders, R., Foge Jensen, P., Jorgensen, M. (2017). Risks of Cardiovascular Adverse Events and Death in Patients with Previous Stroke Undergoing Emergency Noncardiac, Nonintracranial Surgery: The Importance of Operative Timing. Anesthesiology, 127(1), 9-19. [More Information]
Broad, K., Kawano, G., Fierens, I., Rocha-Ferreira, E., Hristova, M., Ezzati, M., Rostami, J., Alonso-Alconada, D., Chaban, B., Hassell, J., et al (2017). Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain. PloS One, 12(3), 173413. [More Information]
Coburn, M., Sanders, R., Neuman, M., Rossaint, R., Matot, I. (2017). We may have improved but we must get better still. European journal of Anaesthesiology, 34(3), 115-117. [More Information]
Roshanov, P., Rochwerg, B., Patel, A., Salehian, O., Duceppe, E., Belley-Cote, E., Guyatt, G., Sessler, D., Le Manach, Y., Borges, F., et al (2017). Withholding versus Continuing Angiotensin-converting Enzyme Inhibitors or Angiotensin II Receptor Blockers before Noncardiac Surgery. Anesthesiology, 126(1), 16-27. [More Information]
Devroe, S., Meeusen, R., Gewillig, M., Cools, B., Poesen, K., Sanders, R., Rex, S. (2017). Xenon as an adjuvant to sevoflurane anesthesia in children younger than 4 years of age, undergoing interventional or diagnostic cardiac catheterization: A randomized controlled clinical trial. Paediatric Anaesthesia, 27(12), 1210-1219. [More Information]

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2016

Venkatesan, S., Okoli, G., Mozid, A., Pickworth, T., Grocott, M., Sanders, R., Myles, P. (2016). Effects of five preoperative cardiovascular drugs on mortality after coronary artery bypab surgery. European journal of Anaesthesiology, 33(1), 49-57. [More Information]
Broad, K., Fierens, I., Fleiss, B., Rocha-Ferreira, E., Ezzati, M., Hassell, J., Alonso-Alconada, D., Bainbridge, A., Kawano, G., Ma, D., et al (2016). Inhaled 45-50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia. Neurobiology of Disease, 87, 29-38. [More Information]
Broad, K., Hassell, J., Fleiss, B., Kawano, G., Ezzati, M., Rocha-Ferreira, E., Hristova, M., Bennett, K., Fierens, I., Burnett, R., et al (2016). Isoflurane exposure induces cell death, microglial activation and modifies the expression of genes supporting neurodevelopment and cognitive function in the male newborn piglet brain. PloS One, 11(11), e0166784. [More Information]
Nakafero, G., Sanders, R., Nguyen-Van-Tam, J., Myles, P. (2016). The association between benzodiazepines and influenza-like illness-related pneumonia and mortality: a survival analysis using UK Primary Care data. Pharmacoepidemiology and Drug Safety, 25(11), 1263-1273. [More Information]

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2015

Jorgensen, M., Hlatky, M., Kober, L., Sanders, R., Torp-Pedersen, C., Gislason, G., Jensen, P., Andersson, C. (2015). ?-blocker-associated risks in patients with uncomplicated hypertension undergoing noncardiac surgery. JAMA Internal Medicine, 175(12), 1923-1931. [More Information]
Nakafero, G., Sanders, R., Nguyen-Van-Tam, J., Myles, P. (2015). Association between benzodiazepine use and exacerbations and mortality in patients with asthma: A matched case-control and survival analysis using the United Kingdom Clinical Practice Research Datalink. Pharmacoepidemiology and Drug Safety, 24(8), 793-802. [More Information]
Munter, N., Stevanovic, A., Rossaint, R., Stoppe, C., Sanders, R., Coburn, M. (2015). CONSORT item adherence in top ranked anaesthesiology journals in 2011: A retrospective analysis. European journal of Anaesthesiology, 32(2), 117-125. [More Information]
Sanders, R., Grover, V., Goulding, J., Godlee, A., Gurney, S., Snelgrove, R., Ma, D., Singh, S., Maze, M., Hussell, T. (2015). Immune cell expression of GABAA receptors and the effects of diazepam on influenza infection. Journal of Neuroimmunology, 282, 97-103. [More Information]

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2014

Hollig, A., Schug, A., Fahlenkamp, A., Rossaint, R., Coburn, M., Brucken, A., Fries, M., Kepp, O., Lemaire, M., Ma, D., et al (2014). Argon: Systematic review on neuro- and organoprotective properties of an “Inert” gas. International Journal of Molecular Sciences, 15(10), 18175-18196. [More Information]
Marchant, N., Sanders, R., Sleigh, J., Vanhaudenhuyse, A., Bruno, M., Brichant, J., Laureys, S., Bonhomme, V. (2014). How electroencephalography serves the anesthesiologist. Clinical EEG and Neuroscience, 45(1), 22-32. [More Information]
Sanders, R. (2014). How important is peri-operative hypertension? Anaesthesia, 69(9), 948-953. [More Information]
Frank, B., Fulton, R., Lees, K., Sanders, R., Alexandrov, A., Bath, P., Bluhmki, E., Bornstein, N., Claesson, L., Curram, J., et al (2014). Impact of benzodiazepines on functional outcome and occurrence of pneumonia in stroke: Evidence from VISTA. International Journal of Stroke, 9(7), 890-894. [More Information]
Nadelson, M., Sanders, R., Avidan, M. (2014). Perioperative cognitive trajectory in adults. British Journal of Anaesthesia, 112(3), 440-451. [More Information]
Ezzati, M., Broad, K., Kawano, G., Faulkner, S., Hassell, J., Fleiss, B., Gressens, P., Fierens, I., Rostami, J., Maze, M., et al (2014). Pharmacokinetics of dexmedetomidine combined with therapeutic hypothermia in a piglet asphyxia model. Acta Anaesthesiologica Scandinavica, 58(6), 733-742. [More Information]
Liu, J., Rossaint, R., Sanders, R., Coburn, M. (2014). Toxic and protective effects of inhaled anaesthetics on the developing animal brain systematic review and update of recent experimental work. European journal of Anaesthesiology, 31(12), 669-677. [More Information]
Ning, J., Mo, L., Zhao, H., Lu, K., Wang, L., Lai, X., Yang, B., Zhao, H., Sanders, R., Ma, D. (2014). Transient regional hypothermia applied to a traumatic limb attenuates distant lung injury following blast limb trauma. Critical Care Medicine, 42(1). [More Information]

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2013

Sanders, R., Godlee, A., Fujimori, T., Goulding, J., Xin, G., Salek-Ardakani, S., Snelgrove, R., Ma, D., Maze, M., Hussell, T. (2013). Benzodiazepine augmented ?-amino-butyric acid signaling increases mortality from pneumonia in mice. Critical Care Medicine, 41(7), 1627-1636. [More Information]
Boly, M., Sanders, R., Mashour, G., Laureys, S. (2013). Consciousness and responsiveness: Lessons from anaesthesia and the vegetative state. Current Opinion in Anaesthesiology, 26(4), 444-449. [More Information]
Sanders, R., Godlee, A., Goulding, J., Ma, D., Maze, M., Hussell, T. (2013). Parenteral fluids do not affect pulmonary immune responses to influenza or susceptibility to secondary bacterial pneumonia in mice. Influenza and Other Respiratory Viruses, 7(6), 895-899. [More Information]
Sanders, R., Nicholson, A., Lewis, S., Smith, A., Alderson, P. (2013). Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery. Cochrane Database of Systematic Reviews, 2013 (7). [More Information]
Bottle, A., Mozid, A., Grocott, H., Walters, M., Lees, K., Aylin, P., Sanders, R. (2013). Preoperative risk factors in 10 418 patients with prior myocardial infarction and 5241 patients with prior unstable angina undergoing elective coronary artery bypass graft surgery. British Journal of Anaesthesia, 111(3), 417-423. [More Information]
Bottle, A., Mozid, A., Grocott, H., Walters, M., Lees, K., Aylin, P., Sanders, R. (2013). Preoperative stroke and outcomes after coronary artery bypass graft surgery. Anesthesiology, 118(4), 885-893. [More Information]
Bottle, A., Sanders, R., Mozid, A., Aylin, P. (2013). Provider profiling models for acute coronary syndrome mortality using administrative data. International Journal of Cardiology, 168(1), 338-343. [More Information]
Sanders, R., Maze, M. (2013). Take Off, Landing, and Fly Anesthesia. PLoS Genetics, 9(9). [More Information]
Obiora, E., Hubbard, R., Sanders, R., Myles, P. (2013). The impact of benzodiazepines on occurrence of pneumonia and mortality from pneumonia: A nested case-control and survival analysis in a population-based cohort. Thorax, 68(2), 163-170. [More Information]
Frank, B., Fulton, R., Weimar, C., Lees, K., Sanders, R. (2013). Use of paracetamol in ischaemic stroke patients: Evidence from VISTA. Acta Neurologica Scandinavica, 128(3), 172-177. [More Information]

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Selected Grants

2025

Does dexmedetomidine influence changes in serum neurofilament light following on-bypass cardiac surgery?, Marshall T, Sanders R, Australian and New Zealand College of Anaesthetists (ANZCA)/2025 Project Grant

2023

A PARADIGM SHIFT IN UNDERSTANDING ANAESTHESIA, Sanders R, Australian and New Zealand College of Anaesthetists (ANZCA)/2024 Project Grant

2022

Collaboration, Mechanisms & Modulation: Improving Perioperative Brain Health, Sanders R, Australia New Zealand College of Anaesthetists (ANZCA)/Academic Enhancement Grant
Delirium, Long-Term Cognition and the Dementia Pathological Trajectory, Hughes C, Sanders R, Teixeira-Pinto A, National Institutes of Health (USA)/Research Support

2020

Receptors, microcircuits and hierarchical connectivity in predictive coding and sensory awareness, Sanders R, National Institutes of Health (USA)/Research Grant
Clarifying the overlapping pathology of delirium and dementia, Sanders R, National Institutes of Health (USA)/Research Support

Faculty of Medicine and Health

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