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Associate Professor Sonia Saad

Associate Professor, Principal Fellow Medicine, Northern Clinical SchoolAdjunct Professor, University of Technology Sydney

Phone

+61 2 99264782

Fax

0299265715

Email

sonia.saad@sydney.edu.au

Resume

Curriculum vitae

Biographical details

Professor Saad's research interest is in progressive renal disease and metabolic disease. She has published over 100 peer reviewed manuscripts in her research area and two provisional patents.Most of her manuscripts are published in high ranking journals, such as JASN (top in the field; IF 9.34), Kidney International (IF 19), microbiome (IF 8.46) Diabetologia (IF 10.46), FASEB Journal (IF 5.804), Scientific Reports (IF 5.228), IJBCB (IF 4.24) and AJP-Renal Physiology (IF 3.79, sandstone Journal). Her work was cited >3000 x. Her h-index is 31 (google scholar) and her RG score to 49.66 (higher than 97.5% of ResearchGate members).She has successfully supervised 9 PhDs, 6 MSc, 3 Honours, and 2 summer students to completion and is currently supervising 3 PhD students affiliated with the University of Sydney and 1 PhD students affiliated with the University of Technology Sydney. She was involved in demonstrating that fluctuating glucose levels has an adverse effect on renal pathology which importantly contributed to the implememtation of a new policy for monitoring postpransial glucose levels in diabetic patients. She was amongst the first in the world to demonstrate the importance of foetal programmimg in early onset metabolic disorders and chronic kidney disease progression which received multiple distinction in scholarship awards from the American/Physiological Society, has fundamentally changes our understanding on the origin of chronic kidney disease and demonstrated that intervention during pregnancy can reduce the risk of chronic kidney disease in the offspring at adulthood.She has expertise in diabetic kidney disease, fibrosis, oxidative stress, mitochondrial function and mitochondrial DNA quantitation. Her current work examines the effect of maternal influences including obesity, smoking and particulate matters on offspring predisposition to chronic kidney disease and epugenetic regulation in disease development. She is also developong a novel tool for early diagnosis and examining the effect of novel natural and pharmaceutical therapies for glycaemic control and renal fibrosis.

Research interests

Prof Saad's primary research focus is in the area of metabolic disease and microvascular/ macrovascular complications of diabetes, including nephropathy and endothelial dysfunction and maternal programming and its effect on offspring predisposition to chronic kidney disease.

Teaching and supervision

Professor Saad has successfully supervised 9 PhD students, 6 Master, 3 honours and 2 summer students to competion. All of whom have had successful career post-graduation.In addition, she is teaching Medical students (MD program, Northern clinical school) and undergraduate medical science and sport science students (University of Technology Sydney), Renal Physiology and Pathophysiology.Her teaching was acknowledged by multiple teaching awards and is of a very high standard with an overall teaching score of 4.42/5. She is currently supervising 3 PhD students.

Current projects

1-Effect of maternal obesity on offspring predisposition to Chronic kidney disease.

2-Antioxidants targeting the mitochondria for the prevention and treatment of kidney disease programmed by maternal smoking.

3-Amniotic fluid and hyperspectral technology-Innovative diagnostic tools for early detection of CKD

4-The role of SIRT1 in offspring kidney disease induced by maternal obesity

5- The role of Lox inhibitors on diabetic nephropathy

6-Novel biomarkers for chronic kidney disease

7-Effect of maternal smoking on offspring neurological disorders

8- Effect of maternal smoking on renal development

9- Nutritional supplements as a treatment options for the management of gestational diabetes

10- Altering the microbiome for glyceamic control and prevention of chronic kidney disease progression

Associations

Prof Saad is associated to Prof Carol Pollock and is a long term collaborator of Prof Hui Chen (University of Technology Sydney) and Prof Ewa Goldys (Macquarie University). She also has multiple international and national collaborators. She has strong collaborations with Biotech and pharmaceutical companies.

Awards and honours

Prof Saad has been successful in obtaining multiple national and internal competitive grants and industrial investment. She has had multiple successful category 1 and 2 grants, most recently from the National Health and Medical Research Council, The Juvenile Diabetes Research Foundation, the Diabetes Australia Research Trust and Rebecca Cooper Foundation in addition to multiple local and commercial grants and philanthropic support. She is the recipient of multiple teaching and travel awards, and awards from Diabetes Australia and the Australian and NewZealand Society of Nephrology. Shewas chosen by the Juvenile Diabetes Research Foundation as one of the top 7 future Research Leaders in Australia. Her work was the subject of multiple distinction in scholarship awards from the American Physiology Society.

Themes

Obesity, Diabetes and Cardiovascular Disease, Reproductive, Maternal and Child Health, Lifespan

Keywords

Diabetes, Nephrology, Obesity & overweight, Chronic kidney disease

Approaches

Cellular/Molecular, Complications, Protein Targetting/Trafficking

Clinical speciality

Nephrology

PhD and master's project opportunities

Mitochondial DNA damage, potential target to reduce the development of renal disorders induced by maternal smoking .

Predicting the future risk of chronic kidney disease in offspring of obese mothers with and without type 2 diabetes

Novel therapy to prevent and treat kidney fibrosis

Current research students

Project title	Research student
Using stem cells for the treatment of acute kidney injury	Chi TRAN

Publications

By Type

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Book Chapters

Nguyen, L., Pollock, C., Saad, S. (2020). The Developmental Mechanisms of Obesity by Maternal Obesity. In Paramjit S. Tappia, Bram Ramjiawan, Naranjan S. Dhalla (Eds.), Pathophysiology of Obesity-Induced Health Complications, (pp. 241-254). Cham: Springer Nature Switzerland. [More Information]
Chen, H., Chan, Y., Oliver, B., Pollock, C., Saad, S. (2019). Maternal Smoking and Fetal Brain Outcome: Mechanisms and Possible Solutions. In Victor Preedy (Eds.), Neuroscience of Nicotine: Mechanisms And Treatment, (pp. 9-16). London: Elsevier. [More Information]
Saad, S., Pollock, C. (2014). The Role of Snails in Renal Epithelial to Mesenchymal Transition. In Owen P. Jenkins (Eds.), Advances in Zoology Research, (pp. 161-170). New York: Nova Science Publishers.

Journals

Oliver, B., Morkaya, J., Wang, B., Lung Chan, Y., Saad, S., Faiz, A., Reyk, D., Verkhratsky, A., Yi, C., Chen, H., et al (2024). Chronic maternal exposure to low-dose PM2.5 impacts cognitive outcomes in a sex-dependent manner. Environment International, 191, 108971. [More Information]
Saad, S., Chen, H. (2024). Diet and Disease Development: Mechanisms, Prevention, and Treatment. Nutrients, 16(21).
Saad, S. (2024). Diet and Disease Development: Present and Future. Nutrients, 16(21). [More Information]
Wu, H., Possell, M., Nguyen, L., Peng, W., Pollock, C., Saad, S. (2024). Evaluation of urinary volatile organic compounds as a novel metabolomic biomarker to assess chronic kidney disease progression. BMC Nephrology, 25(1). [More Information]
Nguyen, L., Pollock, C., Saad, S. (2024). Extraction of high quality and high yield RNA from frozen EDTA blood. Scientific Reports, 14(1). [More Information]
Purcell, A., Rodrigo, N., Cao, Q., Joseph, O., Gill, A., Saad, S., Pollock, C. (2024). Maternal Weight Intervention in the Perinatal Period Improves Liver Health in the Offspring of Mothers with Obesity. Nutrients, 16(1). [More Information]
Rende, U., Ahn, S., Adhikari, S., Moh, E., Pollock, C., Saad, S., Guller, A. (2023). Deciphering the Kidney Matrisome: Identification and Quantification of Renal Extracellular Matrix Proteins in Healthy Mice. International Journal of Molecular Sciences, 24(3). [More Information]
Rende, U., Guller, A., Goldys, E., Pollock, C., Saad, S. (2023). Diagnostic and prognostic biomarkers for tubulointerstitial fibrosis. Journal of Physiology, 601(14), 2801-2826. [More Information]
Chen, H., Burke, C., Donovan, C., Faiz, A., Saad, S., Oliver, B. (2023). E-Cigarette Vapour Alters High-Fat Diet-Induced Systemic Inflammatory Responses but Has No Effect on High-Fat Diet-Induced Changes in Gut Microbiota. Nutrients, 15(7). [More Information]
Feng, M., Bai, X., Thorpe, A., Nguyen, L., Wang, M., Oliver, B., Cho, A., Pollock, C., Saad, S., Chen, H. (2023). Effect of E-Vaping on Kidney Health in Mice Consuming a High-Fat Diet. Nutrients, 15(14). [More Information]
Gangadharan Komala, M., Ong, S., Qadri, M., Elshafie, L., Pollock, C., Saad, S. (2023). Investigating the Regulatory Process, Safety, Efficacy and Product Transparency for Nutraceuticals in the USA, Europe and Australia. Foods, 12(2). [More Information]
Nguyen, L., Pollock, C., Saad, S. (2023). Nutrition and Developmental Origins of Kidney Disease. Nutrients, 15(19). [More Information]
Nguyen, L., Larkin, B., Wang, R., Faiz, A., Pollock, C., Saad, S. (2022). Blood DNA Methylation Predicts Diabetic Kidney Disease Progression in High Fat Diet-Fed Mice. Nutrients, 14(4), 785-1-785-13. [More Information]
Zhang, J., Wong, M., Wong, M., Gross, S., Chen, J., Pollock, C., Saad, S. (2022). Correction: A Cationic-Independent Mannose 6-Phosphate Receptor Inhibitor (PXS64) Ameliorates Kidney Fibrosis by Inhibiting Activation of Transforming Growth Factor-β1. PloS One, 17(1), e0262725. [More Information]
Rodrigo, N., Saad, S., Pollock, C., Glastras, S. (2022). Diet Modification before or during Pregnancy on Maternal and Foetal Outcomes in Rodent Models of Maternal Obesity. Nutrients, 14(10), 2154. [More Information]
Chen, H., Oliver, B., Pant, A., Olivera, A., Poronnik, P., Pollock, C., Saad, S. (2022). Effects of air pollution on human health - Mechanistic evidence suggested by in vitro and in vivo modelling. Environmental Research. [More Information]
Wu, H., Goldys, E., Pollock, C., Saad, S. (2022). Exfoliated Kidney Cells from Urine for Early Diagnosis and Prognostication of CKD: The Way of the Future? International Journal of Molecular Sciences, 23(14), 1-14. [More Information]
Sukjamnong, S., Chen, H., Saad, S., Santiyanont, R. (2022). Fimbristylis ovata and Artemisia vulgaris extracts inhibited AGE-mediated RAGE expression, ROS generation, and inflammation in THP-1 cells. Toxicological research, 38(3), 331-343. [More Information]
Chen, H., Chan, Y., Thorpe, A., Pollock, C., Saad, S., Oliver, B. (2022). Inhaled or Ingested, Which Is Worse, E-Vaping or High-Fat Diet? Frontiers in Immunology, 13, 1-8. [More Information]
Larkin, B., Nguyen, L., Hou, M., Glastras, S., Chen, H., Faiz, A., Chen, J., Wang, R., Pollock, C., Saad, S. (2022). Low-dose hydralazine reduces albuminuria and glomerulosclerosis in a mouse model of obesity-related chronic kidney disease. Diabetes, Obesity and Metabolism, 10, 1939-1949. [More Information]
Bell, K., Saad, S., Tillett, B., McGuire, H., Bordbar, S., Yap, Y., Nguyen, L., Wilkins, M., Corley, S., Brodie, S., Duong, S., Wright, C., Twigg, S., Fazekas de St Groth, B., et al (2022). Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation. Microbiome, 10(1). [More Information]
Habibalahi, A., Campbell, J., Mahbub, S., Anwer, A., Nguyen, L., Gill, A., Wong, M., Chou, A., Pollock, C., Saad, S., et al (2022). moRphology - dEep Learning Imaging Cells (RELIC) - to Differentiate Between Normal and Pathological Kidney Exfoliated Cells. bioRxiv. [More Information]
Chen, H., van Reyk, D., Oliveira, A., Chan, Y., Town, S., Rayner, B., Pollock, C., Saad, S., George, J., Padula, M., Oliver, B. (2022). Sex-dependent responses to maternal exposure to PM2.5 in the offspring. Antioxidants, 11(11). [More Information]
Clarence, D., Paudel, K., Manandhar, B., Singh, S., Devkota, H., Panneerselvam, J., Gupta, V., Chitranshi, N., Verma, N., Saad, S., et al (2022). Unravelling the Therapeutic Potential of Nano-Delivered Functional Foods in Chronic Respiratory Diseases. Nutrients, 14(18), 1-37. [More Information]
Li, Y., Pollock, C., Saad, S. (2021). Aberrant dna methylation mediates the transgenerational risk of metabolic and chronic disease due to maternal obesity and overnutrition. Genes, 12(11), 1653. [More Information]
Chen, H., Wang, B., Li, G., Steele, J., Stayte, S., Vissel, B., Chan, Y., Yi, C., Saad, S., Machaalani, R., et al (2021). Brain health is independently impaired by E-vaping and high-fat diet. Brain, Behavior, and Immunity, 92, 57-66. [More Information]
Chen, H., Li, G., Chan, Y., Zhang, H., Gorrell, M., Pollock, C., Saad, S., Oliver, B. (2021). Differential Effects of Vaping' on Lipid and Glucose Profiles and Liver Metabolic Markers in Obese Versus Non-obese Mice. Frontiers in Physiology, 12, 755124. [More Information]
Larkin, B., Saad, S., Glastras, S., Nguyen, L., Hou, M., Chen, H., Wang, R., Pollock, C. (2021). Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet. PloS One, 16(3), e0248854. [More Information]
Nguyen, L., Saad, S., Shi, Y., Wang, R., Chou, A., Gill, A., Yao, Y., Jarolimek, W., Pollock, C. (2021). Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse. Scientific Reports, 11(1), 12437. [More Information]
Wang, B., Chan, Y., Li, G., Ho, K., Anwer, A., Smith, B., Guo, H., Jalaludin, B., Herbert, C., Thomas, P., Chapman, D., Saad, S., Oliver, B., et al (2021). Maternal particulate matter exposure impairs lung health and is associated with mitochondrial damage. Antioxidants, 10(7), 1029. [More Information]
Mahbub, S., Nguyen, L., Habibalahi, A., Campbell, J., Anwer, A., Qadri, U., Gill, A., Chou, A., Wong, M., Gosnell, M., et al (2021). Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features. Scientific Reports, 11(1), 10655. [More Information]
Larkin, B., Nguyen, L., Hou, M., Glastras, S., Chen, H., Wang, R., Pollock, C., Saad, S. (2021). Novel Role of Gestational Hydralazine in Limiting Maternal and Dietary Obesity-Related Chronic Kidney Disease. Frontiers in Cell and Developmental Biology, 9, 705263. [More Information]
Chen, H., Oliver, B., Pant, A., Olivera, A., Poronnik, P., Pollock, C., Saad, S. (2021). Particulate matter, an intrauterine toxin affecting foetal development and beyond. Antioxidants, 10(5), 732. [More Information]
Mahbub, S., Nguyen, L., Habibalahi, A., Campbell, J., Anwer, A., Qadri, U., Gill, A., Chou, A., Wong, M., Gosnell, M., Pollock, C., Saad, S. (2021). Publisher Correction: Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features. Scientific Reports, 11(1). [More Information]
Zaky, A., Glastras, S., Wong, M., Pollock, C., Saad, S. (2021). The role of the gut microbiome in diabetes and obesity-related kidney disease. International Journal of Molecular Sciences, 22(17), 9641. [More Information]
Li, G., Chan, Y., Wang, B., Saad, S., George, J., Oliver, B., Chen, H. (2020). E-cigarettes damage the liver and alter nutrient metabolism in pregnant mice and their offspring. Annals of the New York Academy of Sciences, 1475 (1), 64-77. [More Information]
Larkin, B., Nguyen, L., Glastras, S., Gangadharan Komala, M., Pollock, C., Saad, S. (2020). Epigenetic regulation of ILDR2 in the cord blood of obese mothers. Translational Metabolic Syndrome Research, 3, 6-8. [More Information]
Zakarya, R., Sapkota, A., Chan, Y., Shah, J., Saad, S., Bottle, S., Oliver, B., Gorrie, C., Chen, H. (2020). Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injury. Nitric Oxide: Biology And Chemistry, 97, 57-65. [More Information]
Habibalahi, A., Dashtbani Moghari, M., Campbell, J., Anwer, A., Mahbub, S., Gosnell, M., Saad, S., Pollock, C., Goldys, E. (2020). Non-invasive real-time imaging of reactive oxygen species (ROS) using auto-fluorescence multispectral imaging technique: A novel tool for redox biology. Redox Biology, 34, 1-6. [More Information]
Wang, B., Chan, Y., Zhou, S., Saad, S., Chen, H., Oliver, B. (2020). Offspring sex affects the susceptibility to maternal smoking-induced lung inflammation and the effect of maternal antioxidant supplementation in mice. Journal of Inflammation, 17, 1-11. [More Information]
Nguyen, L., Saad, S., Chen, H., Pollock, C. (2020). Parental sirt1 overexpression attenuate metabolic disorders due to maternal high-fat feeding. International Journal of Molecular Sciences, 21(19), 1-15. [More Information]
Li, G., Saad, S., Wang, B., Oliver, B., Chen, H., Chan, Y. (2020). Replacing smoking with vaping during pregnancy: Impacts on metabolic health in mice. Reproductive Toxicology, 96, 293-299. [More Information]
Wong, M., Saad, S., Wong, M., Stangenberg, S., Jarolimek, W., Schilter, H., Zaky, A., Gill, A., Pollock, C. (2020). Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy. PloS One, 15(6), e0234617. [More Information]
Nguyen, L., Saad, S., Pollock, C. (2020). The renal expression of epigenetic biomarkers for diabetic nephropathy. Translational Metabolic Syndrome Research, 3, 21-24. [More Information]
Li, G., Chan, Y., Sukjamnong, S., Anwer, A., Vindin, H., Padula, M., Zakarya, R., George, J., Oliver, B., Saad, S., et al (2019). A Mitochondrial Specific Antioxidant Reverses Metabolic Dysfunction and Fatty Liver Induced by Maternal Cigarette Smoke in Mice. Nutrients, 11(7), 1-14. [More Information]
Li, G., Chan, Y., Nguyen, L., Mak, C., Zaky, A., Anwer, A., Shi, Y., Nguyen, T., Pollock, C., Oliver, B., Saad, S., et al (2019). Impact of maternal e-cigarette vapor exposure on renal health in the offspring. Annals of the New York Academy of Sciences, 1452 (1), 65-77. [More Information]
Stangenberg, S., Nguyen, L., Chan, Y., Zaky, A., Pollock, C., Chen, H., Saad, S. (2019). Maternal L-carnitine supplementation ameliorates renal underdevelopment and epigenetic changes in male mice offspring due to maternal smoking. Clinical and Experimental Pharmacology and Physiology, 46(2), 183-193. [More Information]
Wang, B., Hui, C., Ho, K., Saad, S. (2019). Maternal particulate matter exposure during pregnancy affected offspring’s lung health. European Respiratory Journal, 54(suppl 63), PA3350. [More Information]
Chan, Y., Wang, B., Chen, H., Ho, K., Cao, J., Hai, G., Jalaludin, B., Herbert, C., Thomas, P., Saad, S., et al (2019). Pulmonary inflammation induced by low dose particulate matter exposure in mice. AJP: Lung Cellular and Molecular Physiology, 317(3), L424-L430. [More Information]
Nguyen, L., Mak, C., Chen, H., Zaky, A., Wong, M., Pollock, C., Saad, S. (2019). SIRT1 Attenuates Kidney Disorders in Male Offspring Due to Maternal High-Fat Diet. Nutrients, 11(1), 1-14. [More Information]
Nguyen, L., Chen, H., Zaky, A., Pollock, C., Saad, S. (2019). SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high-fat feeding. Journal of Physiology, 597(2), 467-480. [More Information]
Larkin, B., Glastras, S., Chen, H., Pollock, C., Saad, S. (2018). DNA methylation and the potential role of demethylating agents in prevention of progressive chronic kidney disease. The FASEB Journal, 32(10), 5215-5226. [More Information]
Li, G., Saad, S., Oliver, B., Chen, H. (2018). Heat or Burn? Impacts of Intrauterine Tobacco Smoke and E-Cigarette Vapor Exposure on the Offspring's Health Outcome. Toxics, 6(3), 43. [More Information]
Chen, H., Chan, Y., Linnane, C., Mao, Y., Anwer, A., Sapkota, A., Annissa, T., Herok, G., Vissel, B., Oliver, B., Saad, S., et al (2018). L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury. Scientific Reports, 8(1), 1-16. [More Information]
Stangenberg, S., Saad, S., Schilter, H., Zaky, A., Gill, A., Pollock, C., Wong, M. (2018). Lysyl oxidase-like 2 inhibition ameliorates glomerulosclerosis and albuminuria in diabetic nephropathy. Scientific Reports, 8(1), 1-10. [More Information]
Saad, S., Al-Odat, I., Chan, Y., McGrath, K., Pollock, C., Oliver, B., Chen, H. (2018). Maternal L-carnitine supplementation improves glucose and lipid profiles in female offspring of dams exposed to cigarette smoke. Clinical and Experimental Pharmacology and Physiology, 45(7), 694-703. [More Information]
Glastras, S., Chen, H., Pollock, C., Saad, S. (2018). Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring. Bioscience Reports, 38(2), 1-15. [More Information]
Sukjamnong, S., Chan, Y., Zakarya, R., Nguyen, L., Anwer, A., Zaky, A., Santiyanont, R., Oliver, B., Goldys, E., Saad, S., et al (2018). MitoQ supplementation prevent long-term impact of maternal smoking on renal development, oxidative stress and mitochondrial density in male mice offspring. Scientific Reports, 8(1), 6631. [More Information]
Chen, H., Li, G., Chan, Y., Nguyen, T., van Reyk, D., Saad, S., Oliver, B. (2018). Modulation of neural regulators of energy homeostasis, and of inflammation, in the pups of mice exposed to e-cigarettes. Neuroscience Letters, 684, 61-66. [More Information]
Nguyen, L., Chen, H., Mak, C., Zaky, A., Pollock, C., Saad, S. (2018). SRT1720 attenuates obesity and insulin resistance but not liver damage in the offspring due to maternal and postnatal high-fat diet consumption. American Journal of Physiology - Endocrinology and Metabolism, 315(2), E196-E203. [More Information]
Sukjamnong, S., Chan, Y., Zakarya, R., Saad, S., Sharma, P., Santiyanont, R., Chen, H., Oliver, B. (2017). Effect of long-term maternal smoking on the offspring's lung health. American Journal of Physiology: Lung Cellular and Molecular Physiology, 313(2), L416-L423. [More Information]
Chan, Y., Saad, S., Machaalani, R., Oliver, B., Vissel, B., Pollock, C., Jones, N., Chen, H. (2017). Maternal cigarette smoke exposure worsens neurological outcomes in adolescent offspring with hypoxic-ischemic injury. Frontiers in Molecular Neuroscience, 10, 1-17. [More Information]
Nguyen, L., Saad, S., Tan, Y., Pollock, C., Chen, H. (2017). Maternal high-fat diet induces metabolic stress response disorders in offspring hypothalamus. Journal of Molecular Endocrinology, 59(1), 81-92. [More Information]
Chan, Y., Saad, S., Al-Odat, I., Oliver, B., Pollock, C., Jones, N., Chen, H. (2017). Maternal L-carnitine supplementation improves brain health in offspring from cigarette smoke exposed mothers. Frontiers in Molecular Neuroscience, 10, 1-15. [More Information]
Nguyen, L., Chen, H., Pollock, C., Saad, S. (2017). SIRT1 reduction is associated with sex-specific dysregulation of renal lipid metabolism and stress responses in offspring by maternal high-fat diet. Scientific Reports, 7(1), 1-13. [More Information]
Glastras, S., Chen, H., Tsang, M., Teh, R., McGrath, R., Zaky, A., Chen, J., Wong, M., Pollock, C., Saad, S. (2017). The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet. PloS One, 12(2), 1-17. [More Information]
Glastras, S., Chen, H., McGrath, R., Zaky, A., Gill, A., Pollock, C., Saad, S. (2016). Effect of GLP-1 Receptor Activation on Offspring Kidney Health in a Rat Model of Maternal Obesity. Scientific Reports, 6, 1-12. [More Information]
Chan, Y., Saad, S., Al-Odat, I., Zaky, A., Oliver, B., Pollock, C., Li, W., Jones, N., Chen, H. (2016). Impact of maternal cigarette smoke exposure on brain and kidney health outcomes in female offspring. Clinical and Experimental Pharmacology and Physiology, 43(12), 1168-1176. [More Information]
Chan, Y., Saad, S., Pollock, C., Oliver, B., Al-Odat, I., Zaky, A., Jones, N., Chen, H. (2016). Impact of maternal cigarette smoke exposure on brain inflammation and oxidative stress in male mice offspring. Scientific Reports, 6, 1-12. [More Information]
Yaghobian Azari, D., Don, A., Yaghobian, S., Chen, X., Pollock, C., Saad, S. (2016). Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy. Clinical and Experimental Pharmacology and Physiology, 43(1), 56-66. [More Information]
Glastras, S., Tsang, M., Teh, R., Chen, H., McGrath, R., Zaky, A., Pollock, C., Saad, S. (2016). Maternal Obesity Promotes Diabetic Nephropathy in Rodent Offspring. Scientific Reports, 6, 1-9. [More Information]
Chen, H., Chan, Y., Nguyen, L., Mao, Y., de Rosa, A., Beh, I., Chee, C., Oliver, B., Herok, G., Saad, S., et al (2016). Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations. Clinical and Experimental Pharmacology and Physiology, 43(11), 1107-1114. [More Information]
Glastras, S., Chen, H., Teh, R., McGrath, R., Chen, J., Pollock, C., Wong, M., Saad, S. (2016). Mouse models of diabetes, obesity and related kidney disease. PloS One, 11(8), 1-15. [More Information]
Gosnell, M., Anwer, A., Mahbub, S., Menon Perinchery, S., Inglis, D., Adhikary, P., Jazayeri, J., Cahill, M., Saad, S., Pollock, C., et al (2016). Quantitative non-invasive cell characterisation and discrimination based on multispectral autofluorescence features. Scientific Reports, 6, 1-11. [More Information]
Nguyen, L., Chen, H., Pollock, C., Saad, S. (2016). Sirtuins-mediators of maternal obesity-induced complications in offspring? The FASEB Journal, 30(4), 1383-1390. [More Information]
Zhang, J., Wong, M., Wong, M., Gross, S., Chen, J., Pollock, C., Saad, S. (2015). A Cationic-Independent Mannose 6-Phosphate Receptor Inhibitor (PXS64) Ameliorates Kidney Fibrosis by Inhibiting Activation of Transforming Growth Factor-Î²1. PloS One, 10(2), 1-15. [More Information]
Stangenberg, S., Chen, H., Wong, M., Pollock, C., Saad, S. (2015). Fetal programming of chronic kidney disease: The role of maternal smoking, mitochondrial dysfunction, and epigenetic modfification. American Journal of Physiology: Renal Physiology, 308(11), F1189-F1196. [More Information]
Glastras, S., Wong, M., Chen, H., Zhang, J., Zaky, A., Pollock, C., Saad, S. (2015). FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity. Nutrition and Metabolism, 12(1), 1-13. [More Information]
Nguyen, L., Stangenberg, S., Chen, H., Al-Odat, I., Chan, Y., Gosnell, M., Anwer, A., Goldys, E., Pollock, C., Saad, S. (2015). L carnitine reverses maternal cigarette smoke exposure induced renal oxidative stress and mitochondrial dysfunction in mouse offspring. American Journal of Physiology: Renal Physiology, 308(7), F689-F696. [More Information]
Stangenberg, S., Nguyen, L., Chen, H., Al-Odat, I., Killingsworth, M., Gosnell, M., Anwer, A., Goldys, E., Pollock, C., Saad, S. (2015). Oxidative stress, mitochondrial perturbations and fetal programming of renal disease induced by maternal smoking. International Journal of Biochemistry and Cell Biology, 64, 81-90. [More Information]
Chan, Y., Saad, S., Simar, D., Oliver, B., McGrath, K., van Reyk, D., Bertrand, P., Gorrie, C., Pollock, C., Chen, H. (2015). Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams. International Journal of Developmental Neuroscience, 46, 67-75. [More Information]
Mreich, E., Chen, X., Zaky, A., Pollock, C., Saad, S. (2015). The role of KrÃ¼ppel-like factor 4 in transforming growth factor-Î²-induced inflammatory and fibrotic responses in human proximal tubule cells. Clinical and Experimental Pharmacology and Physiology, 42(6), 680-686. [More Information]
Chen, H., Simar, D., Pegg, K., Saad, S., Palmer, C., Morris, M. (2014). Exendin-4 is effective against metabolic disorders induced by intrauterine and postnatal overnutrition in rodents. Diabetologia, 57(3), 614-622. [More Information]
Wong, M., Saad, S., Zhang, J., Gross, S., Jarolimek, W., Schilter, H., Chen, J., Gill, A., Pollock, C., Wong, M. (2014). Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model. AJP: Renal Physiology (Online), 307(8), F908-F916. [More Information]
Al-Odat, I., Chen, H., Chan, Y., Amgad, S., Wong, M., Gill, A., Pollock, C., Saad, S. (2014). The Impact of Maternal Cigarette Smoke Exposure in a Rodent Model on Renal Development in the Offspring. PloS One, 9(7), 1-10. [More Information]
Pegg, K., Zhang, J., Pollock, C., Saad, S. (2013). Combined effects of PPARÎ³ agonists and epidermal growth factor receptor inhibitors in human proximal tubule cells. PPAR Research, 2013, 1-8. [More Information]
Chen, H., Al-Odat, I., Pollock, C., Saad, S. (2013). Fetal Programming of Renal Development - Influence of Maternal Smoking. Journal of Diabetes & Metabolism, 2013 (S9), 1-7. [More Information]
Chen, H., Dorrigan, A., Saad, S., Hare, D., Cortie, M., Valenzuela, S. (2013). In Vivo Study of Spherical Gold Nanoparticles: Inflammatory Effects and Distribution in Mice. PloS One, 8(2), 1-8. [More Information]
Yong, R., Chen, X., Shen, S., Vijayaraj, S., Ma, Q., Pollock, C., Saad, S. (2013). Plumbagin Ameliorates Diabetic Nephropathy via Interruption of Pathways that Include NOX4 Signalling. PloS One, 8(8), 1-13. [More Information]
Saad, S., Zhang, J., Yong, R., Yaghobian, D., Wong, M., Kelly, D., Chen, X., Pollock, C. (2013). Role of the EGF receptor in PPARgamma-mediated sodium and water transport in human proximal tubule cells. Diabetologia, 56(5), 1174-1182. [More Information]
Wong, M., Saad, S., Pollock, C., Wong, M. (2013). Semicarbazide-sensitive amine oxidase and kidney disease. American Journal of Physiology: Renal Physiology, 305(12), F1637-F1644. [More Information]
Chen, H., Saad, S., Sandow, S., Bertrand, P. (2012). Cigarette Smoking and Brain Regulation of Energy Homeostasis. Frontiers in Pharmacology, 3, 1-8. [More Information]
Panchapakesan, U., Pollock, C., Saad, S. (2011). Renal epidermal growth factor receptor: Its role in sodium and water homeostasis in diabetic nephropathy. Clinical and Experimental Pharmacology and Physiology, 38(2), 84-88. [More Information]
Sumual, S., Saad, S., Tang, O., Yong, R., McGinn, C., Chen, X., Pollock, C. (2010). Differential Regulation of Snail by Hypoxia and Hyperglycemia in Human Proximal Tubule Cells. International Journal of Biochemistry and Cell Biology, 42(10), 1689-1697. [More Information]
Saad, S., Stanners, S., Yong, R., Tang, O., Pollock, C. (2010). Notch mediated epithelial to mesenchymal transformation is associated with increased expression of the Snail transcription factor. International Journal of Biochemistry and Cell Biology, 42(7), 1115-1122. [More Information]
Panchapakesan, U., Pollock, C., Saad, S. (2009). Review Article: Importance of the kidney proximal tubular cells in thiazolidinedione-mediated sodium and water uptake. Nephrology, 14(3), 298-301. [More Information]
Stevens, V., Saad, S., Poronnik, P., Fenton Lee, C., Polhill, T., Pollock, C. (2008). The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells. Nephrology, Dialysis, Transplantation, 23(6), 1834-1843. [More Information]
Saad, S., Agapiou, D., Chen, X., Stevens, V., Pollock, C. (2008). The role of Sgk-1 in the upregulation of transport proteins by PPAR-{gamma} agonists in human proximal tubule cells. Nephrology, Dialysis, Transplantation, 24(4), 1130-1141. [More Information]
Stevens, V., Saad, S., Chen, X., Pollock, C. (2007). The interdependence of EGF-R and SGK-1 in fibronectin expression in primary kidney cortical fibroblast cells. International Journal of Biochemistry and Cell Biology, 39(5), 1047-1054. [More Information]
Saad, S., Stevens, V., Wassef, L., Poronnik, P., Kelly, D., Gilbert, R., Pollock, C. (2005). High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule. Kidney International, 68(3), 985-997. [More Information]
Zafiriou, S., Stanners, S., Saad, S., Polhill, T., Poronnik, P., Pollock, C. (2005). Pioglitazone Inhibits Cell Growth and Reduces Matrix Production in Human Kidney Fibroblasts. Journal of the American Society of Nephrology, 16(3), 638-645. [More Information]
McGowan, E., Saad, S., Bendall, L., Bradstock, K., Clarke, C. (2004). Effect Of Progesterone Receptor A Predominance On Breast Cancer Cell Migration Into Bone Marrow Fibroblasts. Breast Cancer Research and Treatment, 83(3), 211-220. [More Information]
Polhill, T., Saad, S., Poronnik, P., Fulcher, G., Pollock, C. (2004). Short-Term Peaks In Glucose Promote Renal Fibrogenesis Independently Of Total Glucose Exposure. American Journal of Physiology: Renal Physiology, 287(2), F268-F273. [More Information]
McGinn, C., Saad, S., Poronnik, P., Pollock, C. (2003). High glucose-mediated effects on endothelial cell proliferation occur via p38 MAP kinase. American Journal of Physiology - Endocrinology and Metabolism, 285, E708-E717.
Saad, S., Gottlieb, D., Bradstock, K., Overall, C., Bendall, L. (2002). Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts. Cancer Research, 62, 283-289.
Saad, S., Bendall, L., James, A., Gottlieb, D., Bradstock, K. (2000). Induction of matrix metalloproteinases MMP-1 and MMP-2 by co-culture of breast cancer cells and bone marrow fibroblasts. Breast Cancer Research and Treatment, 63(2), 105-115.

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Conferences

Goldys, E., Gosnell, M., Anwer, A., Cassano, J., Sue, C., Mahbub, S., Menon Perinchery, S., Inglis, D., Adhikary, P., Jazayeri, J., Saad, S., Pollock, C., et al (2016). Deconstructing autofluorescence: non-invasive detection and monitoring of biochemistry in cells and tissues. Conference on Optical Biopsy XIV - Toward Real-Time Spectroscopic Imaging and Diagnosis, Canada: SPIE. [More Information]
Gosnell, M., Anwer, A., Cassano, J., Sue, C., Mahbub, S., Pernichery, S., Inglis, D., Nadort, A., Adhikary, P., Jazayeri, J., Saad, S., Pollock, C., et al (2016). Non-Invasive Detection and Monitoring of Biochemistry in Cells and Tissues by Decomposing Autofluorescence. Asia Communications and Photonics Conference (ACP 2016), Wuhan: Osa.

Report

Chen, H., Steele, J., Li, G., Chan, Y., Oliver, B., Saad, S., Machaalani, R. (2019). E-vapour inhalation–How does it affect memory?.

By Year

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2024

Oliver, B., Morkaya, J., Wang, B., Lung Chan, Y., Saad, S., Faiz, A., Reyk, D., Verkhratsky, A., Yi, C., Chen, H., et al (2024). Chronic maternal exposure to low-dose PM2.5 impacts cognitive outcomes in a sex-dependent manner. Environment International, 191, 108971. [More Information]
Saad, S., Chen, H. (2024). Diet and Disease Development: Mechanisms, Prevention, and Treatment. Nutrients, 16(21).
Saad, S. (2024). Diet and Disease Development: Present and Future. Nutrients, 16(21). [More Information]
Wu, H., Possell, M., Nguyen, L., Peng, W., Pollock, C., Saad, S. (2024). Evaluation of urinary volatile organic compounds as a novel metabolomic biomarker to assess chronic kidney disease progression. BMC Nephrology, 25(1). [More Information]
Nguyen, L., Pollock, C., Saad, S. (2024). Extraction of high quality and high yield RNA from frozen EDTA blood. Scientific Reports, 14(1). [More Information]
Purcell, A., Rodrigo, N., Cao, Q., Joseph, O., Gill, A., Saad, S., Pollock, C. (2024). Maternal Weight Intervention in the Perinatal Period Improves Liver Health in the Offspring of Mothers with Obesity. Nutrients, 16(1). [More Information]

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2023

Rende, U., Ahn, S., Adhikari, S., Moh, E., Pollock, C., Saad, S., Guller, A. (2023). Deciphering the Kidney Matrisome: Identification and Quantification of Renal Extracellular Matrix Proteins in Healthy Mice. International Journal of Molecular Sciences, 24(3). [More Information]
Rende, U., Guller, A., Goldys, E., Pollock, C., Saad, S. (2023). Diagnostic and prognostic biomarkers for tubulointerstitial fibrosis. Journal of Physiology, 601(14), 2801-2826. [More Information]
Chen, H., Burke, C., Donovan, C., Faiz, A., Saad, S., Oliver, B. (2023). E-Cigarette Vapour Alters High-Fat Diet-Induced Systemic Inflammatory Responses but Has No Effect on High-Fat Diet-Induced Changes in Gut Microbiota. Nutrients, 15(7). [More Information]
Feng, M., Bai, X., Thorpe, A., Nguyen, L., Wang, M., Oliver, B., Cho, A., Pollock, C., Saad, S., Chen, H. (2023). Effect of E-Vaping on Kidney Health in Mice Consuming a High-Fat Diet. Nutrients, 15(14). [More Information]
Gangadharan Komala, M., Ong, S., Qadri, M., Elshafie, L., Pollock, C., Saad, S. (2023). Investigating the Regulatory Process, Safety, Efficacy and Product Transparency for Nutraceuticals in the USA, Europe and Australia. Foods, 12(2). [More Information]
Nguyen, L., Pollock, C., Saad, S. (2023). Nutrition and Developmental Origins of Kidney Disease. Nutrients, 15(19). [More Information]

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2022

Nguyen, L., Larkin, B., Wang, R., Faiz, A., Pollock, C., Saad, S. (2022). Blood DNA Methylation Predicts Diabetic Kidney Disease Progression in High Fat Diet-Fed Mice. Nutrients, 14(4), 785-1-785-13. [More Information]
Zhang, J., Wong, M., Wong, M., Gross, S., Chen, J., Pollock, C., Saad, S. (2022). Correction: A Cationic-Independent Mannose 6-Phosphate Receptor Inhibitor (PXS64) Ameliorates Kidney Fibrosis by Inhibiting Activation of Transforming Growth Factor-β1. PloS One, 17(1), e0262725. [More Information]
Rodrigo, N., Saad, S., Pollock, C., Glastras, S. (2022). Diet Modification before or during Pregnancy on Maternal and Foetal Outcomes in Rodent Models of Maternal Obesity. Nutrients, 14(10), 2154. [More Information]
Chen, H., Oliver, B., Pant, A., Olivera, A., Poronnik, P., Pollock, C., Saad, S. (2022). Effects of air pollution on human health - Mechanistic evidence suggested by in vitro and in vivo modelling. Environmental Research. [More Information]
Wu, H., Goldys, E., Pollock, C., Saad, S. (2022). Exfoliated Kidney Cells from Urine for Early Diagnosis and Prognostication of CKD: The Way of the Future? International Journal of Molecular Sciences, 23(14), 1-14. [More Information]
Sukjamnong, S., Chen, H., Saad, S., Santiyanont, R. (2022). Fimbristylis ovata and Artemisia vulgaris extracts inhibited AGE-mediated RAGE expression, ROS generation, and inflammation in THP-1 cells. Toxicological research, 38(3), 331-343. [More Information]
Chen, H., Chan, Y., Thorpe, A., Pollock, C., Saad, S., Oliver, B. (2022). Inhaled or Ingested, Which Is Worse, E-Vaping or High-Fat Diet? Frontiers in Immunology, 13, 1-8. [More Information]
Larkin, B., Nguyen, L., Hou, M., Glastras, S., Chen, H., Faiz, A., Chen, J., Wang, R., Pollock, C., Saad, S. (2022). Low-dose hydralazine reduces albuminuria and glomerulosclerosis in a mouse model of obesity-related chronic kidney disease. Diabetes, Obesity and Metabolism, 10, 1939-1949. [More Information]
Bell, K., Saad, S., Tillett, B., McGuire, H., Bordbar, S., Yap, Y., Nguyen, L., Wilkins, M., Corley, S., Brodie, S., Duong, S., Wright, C., Twigg, S., Fazekas de St Groth, B., et al (2022). Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation. Microbiome, 10(1). [More Information]
Habibalahi, A., Campbell, J., Mahbub, S., Anwer, A., Nguyen, L., Gill, A., Wong, M., Chou, A., Pollock, C., Saad, S., et al (2022). moRphology - dEep Learning Imaging Cells (RELIC) - to Differentiate Between Normal and Pathological Kidney Exfoliated Cells. bioRxiv. [More Information]
Chen, H., van Reyk, D., Oliveira, A., Chan, Y., Town, S., Rayner, B., Pollock, C., Saad, S., George, J., Padula, M., Oliver, B. (2022). Sex-dependent responses to maternal exposure to PM2.5 in the offspring. Antioxidants, 11(11). [More Information]
Clarence, D., Paudel, K., Manandhar, B., Singh, S., Devkota, H., Panneerselvam, J., Gupta, V., Chitranshi, N., Verma, N., Saad, S., et al (2022). Unravelling the Therapeutic Potential of Nano-Delivered Functional Foods in Chronic Respiratory Diseases. Nutrients, 14(18), 1-37. [More Information]

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2021

Li, Y., Pollock, C., Saad, S. (2021). Aberrant dna methylation mediates the transgenerational risk of metabolic and chronic disease due to maternal obesity and overnutrition. Genes, 12(11), 1653. [More Information]
Chen, H., Wang, B., Li, G., Steele, J., Stayte, S., Vissel, B., Chan, Y., Yi, C., Saad, S., Machaalani, R., et al (2021). Brain health is independently impaired by E-vaping and high-fat diet. Brain, Behavior, and Immunity, 92, 57-66. [More Information]
Chen, H., Li, G., Chan, Y., Zhang, H., Gorrell, M., Pollock, C., Saad, S., Oliver, B. (2021). Differential Effects of Vaping' on Lipid and Glucose Profiles and Liver Metabolic Markers in Obese Versus Non-obese Mice. Frontiers in Physiology, 12, 755124. [More Information]
Larkin, B., Saad, S., Glastras, S., Nguyen, L., Hou, M., Chen, H., Wang, R., Pollock, C. (2021). Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet. PloS One, 16(3), e0248854. [More Information]
Nguyen, L., Saad, S., Shi, Y., Wang, R., Chou, A., Gill, A., Yao, Y., Jarolimek, W., Pollock, C. (2021). Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse. Scientific Reports, 11(1), 12437. [More Information]
Wang, B., Chan, Y., Li, G., Ho, K., Anwer, A., Smith, B., Guo, H., Jalaludin, B., Herbert, C., Thomas, P., Chapman, D., Saad, S., Oliver, B., et al (2021). Maternal particulate matter exposure impairs lung health and is associated with mitochondrial damage. Antioxidants, 10(7), 1029. [More Information]
Mahbub, S., Nguyen, L., Habibalahi, A., Campbell, J., Anwer, A., Qadri, U., Gill, A., Chou, A., Wong, M., Gosnell, M., et al (2021). Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features. Scientific Reports, 11(1), 10655. [More Information]
Larkin, B., Nguyen, L., Hou, M., Glastras, S., Chen, H., Wang, R., Pollock, C., Saad, S. (2021). Novel Role of Gestational Hydralazine in Limiting Maternal and Dietary Obesity-Related Chronic Kidney Disease. Frontiers in Cell and Developmental Biology, 9, 705263. [More Information]
Chen, H., Oliver, B., Pant, A., Olivera, A., Poronnik, P., Pollock, C., Saad, S. (2021). Particulate matter, an intrauterine toxin affecting foetal development and beyond. Antioxidants, 10(5), 732. [More Information]
Mahbub, S., Nguyen, L., Habibalahi, A., Campbell, J., Anwer, A., Qadri, U., Gill, A., Chou, A., Wong, M., Gosnell, M., Pollock, C., Saad, S. (2021). Publisher Correction: Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features. Scientific Reports, 11(1). [More Information]
Zaky, A., Glastras, S., Wong, M., Pollock, C., Saad, S. (2021). The role of the gut microbiome in diabetes and obesity-related kidney disease. International Journal of Molecular Sciences, 22(17), 9641. [More Information]

show 8 more

2020

Li, G., Chan, Y., Wang, B., Saad, S., George, J., Oliver, B., Chen, H. (2020). E-cigarettes damage the liver and alter nutrient metabolism in pregnant mice and their offspring. Annals of the New York Academy of Sciences, 1475 (1), 64-77. [More Information]
Larkin, B., Nguyen, L., Glastras, S., Gangadharan Komala, M., Pollock, C., Saad, S. (2020). Epigenetic regulation of ILDR2 in the cord blood of obese mothers. Translational Metabolic Syndrome Research, 3, 6-8. [More Information]
Zakarya, R., Sapkota, A., Chan, Y., Shah, J., Saad, S., Bottle, S., Oliver, B., Gorrie, C., Chen, H. (2020). Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injury. Nitric Oxide: Biology And Chemistry, 97, 57-65. [More Information]
Habibalahi, A., Dashtbani Moghari, M., Campbell, J., Anwer, A., Mahbub, S., Gosnell, M., Saad, S., Pollock, C., Goldys, E. (2020). Non-invasive real-time imaging of reactive oxygen species (ROS) using auto-fluorescence multispectral imaging technique: A novel tool for redox biology. Redox Biology, 34, 1-6. [More Information]
Wang, B., Chan, Y., Zhou, S., Saad, S., Chen, H., Oliver, B. (2020). Offspring sex affects the susceptibility to maternal smoking-induced lung inflammation and the effect of maternal antioxidant supplementation in mice. Journal of Inflammation, 17, 1-11. [More Information]
Nguyen, L., Saad, S., Chen, H., Pollock, C. (2020). Parental sirt1 overexpression attenuate metabolic disorders due to maternal high-fat feeding. International Journal of Molecular Sciences, 21(19), 1-15. [More Information]
Li, G., Saad, S., Wang, B., Oliver, B., Chen, H., Chan, Y. (2020). Replacing smoking with vaping during pregnancy: Impacts on metabolic health in mice. Reproductive Toxicology, 96, 293-299. [More Information]
Wong, M., Saad, S., Wong, M., Stangenberg, S., Jarolimek, W., Schilter, H., Zaky, A., Gill, A., Pollock, C. (2020). Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy. PloS One, 15(6), e0234617. [More Information]
Nguyen, L., Pollock, C., Saad, S. (2020). The Developmental Mechanisms of Obesity by Maternal Obesity. In Paramjit S. Tappia, Bram Ramjiawan, Naranjan S. Dhalla (Eds.), Pathophysiology of Obesity-Induced Health Complications, (pp. 241-254). Cham: Springer Nature Switzerland. [More Information]
Nguyen, L., Saad, S., Pollock, C. (2020). The renal expression of epigenetic biomarkers for diabetic nephropathy. Translational Metabolic Syndrome Research, 3, 21-24. [More Information]

show 7 more

2019

Li, G., Chan, Y., Sukjamnong, S., Anwer, A., Vindin, H., Padula, M., Zakarya, R., George, J., Oliver, B., Saad, S., et al (2019). A Mitochondrial Specific Antioxidant Reverses Metabolic Dysfunction and Fatty Liver Induced by Maternal Cigarette Smoke in Mice. Nutrients, 11(7), 1-14. [More Information]
Chen, H., Steele, J., Li, G., Chan, Y., Oliver, B., Saad, S., Machaalani, R. (2019). E-vapour inhalation–How does it affect memory?.
Li, G., Chan, Y., Nguyen, L., Mak, C., Zaky, A., Anwer, A., Shi, Y., Nguyen, T., Pollock, C., Oliver, B., Saad, S., et al (2019). Impact of maternal e-cigarette vapor exposure on renal health in the offspring. Annals of the New York Academy of Sciences, 1452 (1), 65-77. [More Information]
Stangenberg, S., Nguyen, L., Chan, Y., Zaky, A., Pollock, C., Chen, H., Saad, S. (2019). Maternal L-carnitine supplementation ameliorates renal underdevelopment and epigenetic changes in male mice offspring due to maternal smoking. Clinical and Experimental Pharmacology and Physiology, 46(2), 183-193. [More Information]
Wang, B., Hui, C., Ho, K., Saad, S. (2019). Maternal particulate matter exposure during pregnancy affected offspring’s lung health. European Respiratory Journal, 54(suppl 63), PA3350. [More Information]
Chen, H., Chan, Y., Oliver, B., Pollock, C., Saad, S. (2019). Maternal Smoking and Fetal Brain Outcome: Mechanisms and Possible Solutions. In Victor Preedy (Eds.), Neuroscience of Nicotine: Mechanisms And Treatment, (pp. 9-16). London: Elsevier. [More Information]
Chan, Y., Wang, B., Chen, H., Ho, K., Cao, J., Hai, G., Jalaludin, B., Herbert, C., Thomas, P., Saad, S., et al (2019). Pulmonary inflammation induced by low dose particulate matter exposure in mice. AJP: Lung Cellular and Molecular Physiology, 317(3), L424-L430. [More Information]
Nguyen, L., Mak, C., Chen, H., Zaky, A., Wong, M., Pollock, C., Saad, S. (2019). SIRT1 Attenuates Kidney Disorders in Male Offspring Due to Maternal High-Fat Diet. Nutrients, 11(1), 1-14. [More Information]
Nguyen, L., Chen, H., Zaky, A., Pollock, C., Saad, S. (2019). SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high-fat feeding. Journal of Physiology, 597(2), 467-480. [More Information]

show 6 more

2018

Larkin, B., Glastras, S., Chen, H., Pollock, C., Saad, S. (2018). DNA methylation and the potential role of demethylating agents in prevention of progressive chronic kidney disease. The FASEB Journal, 32(10), 5215-5226. [More Information]
Li, G., Saad, S., Oliver, B., Chen, H. (2018). Heat or Burn? Impacts of Intrauterine Tobacco Smoke and E-Cigarette Vapor Exposure on the Offspring's Health Outcome. Toxics, 6(3), 43. [More Information]
Chen, H., Chan, Y., Linnane, C., Mao, Y., Anwer, A., Sapkota, A., Annissa, T., Herok, G., Vissel, B., Oliver, B., Saad, S., et al (2018). L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury. Scientific Reports, 8(1), 1-16. [More Information]
Stangenberg, S., Saad, S., Schilter, H., Zaky, A., Gill, A., Pollock, C., Wong, M. (2018). Lysyl oxidase-like 2 inhibition ameliorates glomerulosclerosis and albuminuria in diabetic nephropathy. Scientific Reports, 8(1), 1-10. [More Information]
Saad, S., Al-Odat, I., Chan, Y., McGrath, K., Pollock, C., Oliver, B., Chen, H. (2018). Maternal L-carnitine supplementation improves glucose and lipid profiles in female offspring of dams exposed to cigarette smoke. Clinical and Experimental Pharmacology and Physiology, 45(7), 694-703. [More Information]
Glastras, S., Chen, H., Pollock, C., Saad, S. (2018). Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring. Bioscience Reports, 38(2), 1-15. [More Information]
Sukjamnong, S., Chan, Y., Zakarya, R., Nguyen, L., Anwer, A., Zaky, A., Santiyanont, R., Oliver, B., Goldys, E., Saad, S., et al (2018). MitoQ supplementation prevent long-term impact of maternal smoking on renal development, oxidative stress and mitochondrial density in male mice offspring. Scientific Reports, 8(1), 6631. [More Information]
Chen, H., Li, G., Chan, Y., Nguyen, T., van Reyk, D., Saad, S., Oliver, B. (2018). Modulation of neural regulators of energy homeostasis, and of inflammation, in the pups of mice exposed to e-cigarettes. Neuroscience Letters, 684, 61-66. [More Information]
Nguyen, L., Chen, H., Mak, C., Zaky, A., Pollock, C., Saad, S. (2018). SRT1720 attenuates obesity and insulin resistance but not liver damage in the offspring due to maternal and postnatal high-fat diet consumption. American Journal of Physiology - Endocrinology and Metabolism, 315(2), E196-E203. [More Information]

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2017

Sukjamnong, S., Chan, Y., Zakarya, R., Saad, S., Sharma, P., Santiyanont, R., Chen, H., Oliver, B. (2017). Effect of long-term maternal smoking on the offspring's lung health. American Journal of Physiology: Lung Cellular and Molecular Physiology, 313(2), L416-L423. [More Information]
Chan, Y., Saad, S., Machaalani, R., Oliver, B., Vissel, B., Pollock, C., Jones, N., Chen, H. (2017). Maternal cigarette smoke exposure worsens neurological outcomes in adolescent offspring with hypoxic-ischemic injury. Frontiers in Molecular Neuroscience, 10, 1-17. [More Information]
Nguyen, L., Saad, S., Tan, Y., Pollock, C., Chen, H. (2017). Maternal high-fat diet induces metabolic stress response disorders in offspring hypothalamus. Journal of Molecular Endocrinology, 59(1), 81-92. [More Information]
Chan, Y., Saad, S., Al-Odat, I., Oliver, B., Pollock, C., Jones, N., Chen, H. (2017). Maternal L-carnitine supplementation improves brain health in offspring from cigarette smoke exposed mothers. Frontiers in Molecular Neuroscience, 10, 1-15. [More Information]
Nguyen, L., Chen, H., Pollock, C., Saad, S. (2017). SIRT1 reduction is associated with sex-specific dysregulation of renal lipid metabolism and stress responses in offspring by maternal high-fat diet. Scientific Reports, 7(1), 1-13. [More Information]
Glastras, S., Chen, H., Tsang, M., Teh, R., McGrath, R., Zaky, A., Chen, J., Wong, M., Pollock, C., Saad, S. (2017). The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet. PloS One, 12(2), 1-17. [More Information]

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2016

Goldys, E., Gosnell, M., Anwer, A., Cassano, J., Sue, C., Mahbub, S., Menon Perinchery, S., Inglis, D., Adhikary, P., Jazayeri, J., Saad, S., Pollock, C., et al (2016). Deconstructing autofluorescence: non-invasive detection and monitoring of biochemistry in cells and tissues. Conference on Optical Biopsy XIV - Toward Real-Time Spectroscopic Imaging and Diagnosis, Canada: SPIE. [More Information]
Glastras, S., Chen, H., McGrath, R., Zaky, A., Gill, A., Pollock, C., Saad, S. (2016). Effect of GLP-1 Receptor Activation on Offspring Kidney Health in a Rat Model of Maternal Obesity. Scientific Reports, 6, 1-12. [More Information]
Chan, Y., Saad, S., Al-Odat, I., Zaky, A., Oliver, B., Pollock, C., Li, W., Jones, N., Chen, H. (2016). Impact of maternal cigarette smoke exposure on brain and kidney health outcomes in female offspring. Clinical and Experimental Pharmacology and Physiology, 43(12), 1168-1176. [More Information]
Chan, Y., Saad, S., Pollock, C., Oliver, B., Al-Odat, I., Zaky, A., Jones, N., Chen, H. (2016). Impact of maternal cigarette smoke exposure on brain inflammation and oxidative stress in male mice offspring. Scientific Reports, 6, 1-12. [More Information]
Yaghobian Azari, D., Don, A., Yaghobian, S., Chen, X., Pollock, C., Saad, S. (2016). Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy. Clinical and Experimental Pharmacology and Physiology, 43(1), 56-66. [More Information]
Glastras, S., Tsang, M., Teh, R., Chen, H., McGrath, R., Zaky, A., Pollock, C., Saad, S. (2016). Maternal Obesity Promotes Diabetic Nephropathy in Rodent Offspring. Scientific Reports, 6, 1-9. [More Information]
Chen, H., Chan, Y., Nguyen, L., Mao, Y., de Rosa, A., Beh, I., Chee, C., Oliver, B., Herok, G., Saad, S., et al (2016). Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations. Clinical and Experimental Pharmacology and Physiology, 43(11), 1107-1114. [More Information]
Glastras, S., Chen, H., Teh, R., McGrath, R., Chen, J., Pollock, C., Wong, M., Saad, S. (2016). Mouse models of diabetes, obesity and related kidney disease. PloS One, 11(8), 1-15. [More Information]
Gosnell, M., Anwer, A., Cassano, J., Sue, C., Mahbub, S., Pernichery, S., Inglis, D., Nadort, A., Adhikary, P., Jazayeri, J., Saad, S., Pollock, C., et al (2016). Non-Invasive Detection and Monitoring of Biochemistry in Cells and Tissues by Decomposing Autofluorescence. Asia Communications and Photonics Conference (ACP 2016), Wuhan: Osa.
Gosnell, M., Anwer, A., Mahbub, S., Menon Perinchery, S., Inglis, D., Adhikary, P., Jazayeri, J., Cahill, M., Saad, S., Pollock, C., et al (2016). Quantitative non-invasive cell characterisation and discrimination based on multispectral autofluorescence features. Scientific Reports, 6, 1-11. [More Information]
Nguyen, L., Chen, H., Pollock, C., Saad, S. (2016). Sirtuins-mediators of maternal obesity-induced complications in offspring? The FASEB Journal, 30(4), 1383-1390. [More Information]

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2015

Zhang, J., Wong, M., Wong, M., Gross, S., Chen, J., Pollock, C., Saad, S. (2015). A Cationic-Independent Mannose 6-Phosphate Receptor Inhibitor (PXS64) Ameliorates Kidney Fibrosis by Inhibiting Activation of Transforming Growth Factor-Î²1. PloS One, 10(2), 1-15. [More Information]
Stangenberg, S., Chen, H., Wong, M., Pollock, C., Saad, S. (2015). Fetal programming of chronic kidney disease: The role of maternal smoking, mitochondrial dysfunction, and epigenetic modfification. American Journal of Physiology: Renal Physiology, 308(11), F1189-F1196. [More Information]
Glastras, S., Wong, M., Chen, H., Zhang, J., Zaky, A., Pollock, C., Saad, S. (2015). FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity. Nutrition and Metabolism, 12(1), 1-13. [More Information]
Nguyen, L., Stangenberg, S., Chen, H., Al-Odat, I., Chan, Y., Gosnell, M., Anwer, A., Goldys, E., Pollock, C., Saad, S. (2015). L carnitine reverses maternal cigarette smoke exposure induced renal oxidative stress and mitochondrial dysfunction in mouse offspring. American Journal of Physiology: Renal Physiology, 308(7), F689-F696. [More Information]
Stangenberg, S., Nguyen, L., Chen, H., Al-Odat, I., Killingsworth, M., Gosnell, M., Anwer, A., Goldys, E., Pollock, C., Saad, S. (2015). Oxidative stress, mitochondrial perturbations and fetal programming of renal disease induced by maternal smoking. International Journal of Biochemistry and Cell Biology, 64, 81-90. [More Information]
Chan, Y., Saad, S., Simar, D., Oliver, B., McGrath, K., van Reyk, D., Bertrand, P., Gorrie, C., Pollock, C., Chen, H. (2015). Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams. International Journal of Developmental Neuroscience, 46, 67-75. [More Information]
Mreich, E., Chen, X., Zaky, A., Pollock, C., Saad, S. (2015). The role of KrÃ¼ppel-like factor 4 in transforming growth factor-Î²-induced inflammatory and fibrotic responses in human proximal tubule cells. Clinical and Experimental Pharmacology and Physiology, 42(6), 680-686. [More Information]

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2014

Chen, H., Simar, D., Pegg, K., Saad, S., Palmer, C., Morris, M. (2014). Exendin-4 is effective against metabolic disorders induced by intrauterine and postnatal overnutrition in rodents. Diabetologia, 57(3), 614-622. [More Information]
Wong, M., Saad, S., Zhang, J., Gross, S., Jarolimek, W., Schilter, H., Chen, J., Gill, A., Pollock, C., Wong, M. (2014). Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model. AJP: Renal Physiology (Online), 307(8), F908-F916. [More Information]
Al-Odat, I., Chen, H., Chan, Y., Amgad, S., Wong, M., Gill, A., Pollock, C., Saad, S. (2014). The Impact of Maternal Cigarette Smoke Exposure in a Rodent Model on Renal Development in the Offspring. PloS One, 9(7), 1-10. [More Information]
Saad, S., Pollock, C. (2014). The Role of Snails in Renal Epithelial to Mesenchymal Transition. In Owen P. Jenkins (Eds.), Advances in Zoology Research, (pp. 161-170). New York: Nova Science Publishers.

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2013

Pegg, K., Zhang, J., Pollock, C., Saad, S. (2013). Combined effects of PPARÎ³ agonists and epidermal growth factor receptor inhibitors in human proximal tubule cells. PPAR Research, 2013, 1-8. [More Information]
Chen, H., Al-Odat, I., Pollock, C., Saad, S. (2013). Fetal Programming of Renal Development - Influence of Maternal Smoking. Journal of Diabetes & Metabolism, 2013 (S9), 1-7. [More Information]
Chen, H., Dorrigan, A., Saad, S., Hare, D., Cortie, M., Valenzuela, S. (2013). In Vivo Study of Spherical Gold Nanoparticles: Inflammatory Effects and Distribution in Mice. PloS One, 8(2), 1-8. [More Information]
Yong, R., Chen, X., Shen, S., Vijayaraj, S., Ma, Q., Pollock, C., Saad, S. (2013). Plumbagin Ameliorates Diabetic Nephropathy via Interruption of Pathways that Include NOX4 Signalling. PloS One, 8(8), 1-13. [More Information]
Saad, S., Zhang, J., Yong, R., Yaghobian, D., Wong, M., Kelly, D., Chen, X., Pollock, C. (2013). Role of the EGF receptor in PPARgamma-mediated sodium and water transport in human proximal tubule cells. Diabetologia, 56(5), 1174-1182. [More Information]
Wong, M., Saad, S., Pollock, C., Wong, M. (2013). Semicarbazide-sensitive amine oxidase and kidney disease. American Journal of Physiology: Renal Physiology, 305(12), F1637-F1644. [More Information]

show 3 more

2012

Chen, H., Saad, S., Sandow, S., Bertrand, P. (2012). Cigarette Smoking and Brain Regulation of Energy Homeostasis. Frontiers in Pharmacology, 3, 1-8. [More Information]

2011

Panchapakesan, U., Pollock, C., Saad, S. (2011). Renal epidermal growth factor receptor: Its role in sodium and water homeostasis in diabetic nephropathy. Clinical and Experimental Pharmacology and Physiology, 38(2), 84-88. [More Information]

2010

Sumual, S., Saad, S., Tang, O., Yong, R., McGinn, C., Chen, X., Pollock, C. (2010). Differential Regulation of Snail by Hypoxia and Hyperglycemia in Human Proximal Tubule Cells. International Journal of Biochemistry and Cell Biology, 42(10), 1689-1697. [More Information]
Saad, S., Stanners, S., Yong, R., Tang, O., Pollock, C. (2010). Notch mediated epithelial to mesenchymal transformation is associated with increased expression of the Snail transcription factor. International Journal of Biochemistry and Cell Biology, 42(7), 1115-1122. [More Information]

2009

Panchapakesan, U., Pollock, C., Saad, S. (2009). Review Article: Importance of the kidney proximal tubular cells in thiazolidinedione-mediated sodium and water uptake. Nephrology, 14(3), 298-301. [More Information]

2008

Stevens, V., Saad, S., Poronnik, P., Fenton Lee, C., Polhill, T., Pollock, C. (2008). The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells. Nephrology, Dialysis, Transplantation, 23(6), 1834-1843. [More Information]
Saad, S., Agapiou, D., Chen, X., Stevens, V., Pollock, C. (2008). The role of Sgk-1 in the upregulation of transport proteins by PPAR-{gamma} agonists in human proximal tubule cells. Nephrology, Dialysis, Transplantation, 24(4), 1130-1141. [More Information]

2007

Stevens, V., Saad, S., Chen, X., Pollock, C. (2007). The interdependence of EGF-R and SGK-1 in fibronectin expression in primary kidney cortical fibroblast cells. International Journal of Biochemistry and Cell Biology, 39(5), 1047-1054. [More Information]

2005

Saad, S., Stevens, V., Wassef, L., Poronnik, P., Kelly, D., Gilbert, R., Pollock, C. (2005). High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule. Kidney International, 68(3), 985-997. [More Information]
Zafiriou, S., Stanners, S., Saad, S., Polhill, T., Poronnik, P., Pollock, C. (2005). Pioglitazone Inhibits Cell Growth and Reduces Matrix Production in Human Kidney Fibroblasts. Journal of the American Society of Nephrology, 16(3), 638-645. [More Information]

2004

McGowan, E., Saad, S., Bendall, L., Bradstock, K., Clarke, C. (2004). Effect Of Progesterone Receptor A Predominance On Breast Cancer Cell Migration Into Bone Marrow Fibroblasts. Breast Cancer Research and Treatment, 83(3), 211-220. [More Information]
Polhill, T., Saad, S., Poronnik, P., Fulcher, G., Pollock, C. (2004). Short-Term Peaks In Glucose Promote Renal Fibrogenesis Independently Of Total Glucose Exposure. American Journal of Physiology: Renal Physiology, 287(2), F268-F273. [More Information]

2003

McGinn, C., Saad, S., Poronnik, P., Pollock, C. (2003). High glucose-mediated effects on endothelial cell proliferation occur via p38 MAP kinase. American Journal of Physiology - Endocrinology and Metabolism, 285, E708-E717.

2002

Saad, S., Gottlieb, D., Bradstock, K., Overall, C., Bendall, L. (2002). Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts. Cancer Research, 62, 283-289.

2000

Saad, S., Bendall, L., James, A., Gottlieb, D., Bradstock, K. (2000). Induction of matrix metalloproteinases MMP-1 and MMP-2 by co-culture of breast cancer cells and bone marrow fibroblasts. Breast Cancer Research and Treatment, 63(2), 105-115.

Selected Grants

2022

Epredia CryoStar NX70 Cryostat 220-240V, 50Hz, Figtree G, Aubrey K, Saad S, National Health and Medical Research Council (NHMRC)/Equipment Grant

2021

Assessing urinary tubular cells in chronic kidney disease by deep learning early diagnostics without kidney biopsy., Saad S, Pollock C, Diabetes Australia/Diabetes Research Grant Program

2020

Analysis of extracellular matrix dynamics in renal fibrosis: towards discovering new therapeutic targets and biomarkers, Saad S, Pollock C, Health Administration Corporation/Research Grant

2018

Specialized dietary intervention in human type 1 diabetes, Saad S, Marino E, Bell K, Juvenile Diabetes Research Foundation - JDRF (Australia)/Australian Type 1 Diabetes Clinical Research Network: Centres and Concept Proposals

2017

A novel diagnostic method to determine the likelihood of kidney fibrosis and progressive CKD in patients with diabetes mellitus and other forms of chronic proteinuric renal disease, Pollock C, Saad S, Goldys E, Fulcher G, Wong M, National Health and Medical Research Council (NHMRC)/Project Grants
Novel treatment for kidney disease related to dietary obesity and maternal obesity, Saad S, Rebecca L Cooper Medical Research Foundation/Research Grant
Predicting the future risk of chronic kidney disease in offspring of obese mothers with and without type 2 diabetes, Pollock C, Saad S, Chen H, Stirzaker C, Diabetes Australia/Research Grant

2016

CDIP Industry & Community Engagement Fund 2016 - USYD and Gratuk Technologies Pty. Ltd - SONIA SAAD, Saad S, Pollock C, DVC Research/Industry & Community Engagement Seed Fund (I&CEF)
Impact of maternal obesity on the development of chronic kidney disease in offspring, Saad S, Sydney Medical School/Energizer Grant
The Role of SIRT1 in maternal obesity induced chronic kidney disease in the offspring, Saad S, Sydney Medical School/Mid Career Researcher Scheme (MCRS)

2014

Impact of maternal obesity on susceptibility to diabetic nephropathy, Pollock C, Saad S, Diabetes Australia Research Trust (DART)/Diabetes Research Grant Program

2009

Distinct ligands of PPARg mediate divergent inflammatory and fibrotic effects in endolthelium and proximal tubule, Saad S, Pollock C, Ramsay Health Care/RNSH Bridging Support for Senior Scientist

2006

The role of peroxisome proliferator-activated receptor gamma in sodium transport in human proximal tubule cells, Pollock C, Saad S, National Health and Medical Research Council (NHMRC)/Project Grants

Prof Saad has been involved in the management (Committee Chair) of the New Horizons Meeting(previously Combined Scientific Research Meeting) which involves the Kolling Institute USyd and the University of Technology Sydney. She has expended this meeting to also include Royal North Shore Hospital, the Woolcock Institute and the Centenary Institute. Since 2004, She has been successful in fundraising this conference from commercial sponsorsand providing over $10,000/year is awards for Staff and students. The educational, translational and commercial leverage that has resulted from this meeting at a national and international level (for example the establishment of the SPARK Sydney program in collaboration with Stanford University School of Medicine USA) attest for my leadership ability. She received an eminent contribution award from the Director of SPARK to recognise her efforts. She is also an organizing committee member for the international obesity-2018 conference, a member of the Scientific Advisory Board, Orlando, USA; an active member of the Australian and New Zealand Society of Nephrology Meeting, a member of the Education and Training Committee of the ANZSN (Leader of the Gender Equity, Diversity and Inclusiveness Liaison) and was a Co-Chair of the Scientific Committee, responsible for the Scientific Research Program and for the management of the Career sessions at the ANZSN Meeting in 2022, She is a member of the Scientific Staff Council. In addition, she has acted as an interviewer for Medical students (Medical entry program) and higher degree by research (HDR) students and has been involved in the HDR students recruitment, annual review process, and students awards. She is a panel member of the HDR supervisory forum, anexternal reviewer on the University of Sydney TGA panel and a PC2 manager. She was involved in making policies for PC2 research practice and the decisions making related to Research Support Services and Research Infrastructure across the Kolling Institute.She is also a regular reviewer of multiple journals in my research area (e.g. JASN (top in the field), IJBCB, NDT, AJP-Renal Physiology, The Asia pacific Journal of Endocrinology, Kidney International, Molecular and cell biochemistry, Clinical Science, International Journal of Obesity, PLoSOne etc.) and an external reviewer for PhD thesis’. She is a regular assessor for different national and international funding bodies including NHMRC, Diabetes Australia Research Trust fund, Dutch Kidney Foundation Kolff Grants (Netherlands), Diabetes UK (London)and National Kidney Foundation (Hungary) and was a medical panel member of the Lebanese Diaspora Energy conference Oceania which included government representatives, the Minister of foreign affairs and over 500 people from the community which attests for her national and international standing. She is a senior editor for the Clinical and Experimental Journal of Physiology and Pharmacology,a Senior Editor for Translational Metabolic Syndrome Research, a Board member and Associate Editor for Frontiers in Endocrinology and an Editorial Board member for Nutrients.

In the media

Prof Saad's research was featured as research highlights on the HCPLive website (MD magazine which covers high impact Medical news for physicians) in 2016. Early this year, I received a distinction in scholarship award from the American Physiology Society for one of my articles which was selected by the Society as the best recently published articles in physiological research (http://apsselect.physiology.org/). Few of my research publications were reported on Global medical discoveries, MD magazines, and were the subject of a multiple press reports by Nicotinepolicy, Medical Press, Get STEM and Medical News Today, Healthglu, ENVIVA Paediatric Care, MedWorm, Medical Press and U R The Voice UK as follows:

12/6/2016. Maternal Obesity Significantly Increases Chronic Kidney Disease Risk in Child.

http://www.mdmag.com/conference-coverage/ada-2016/maternal-obesity-significantly-increases-chronic-kidney-disease-risk-in-child

8/8/2017 Research sheds new light on why smoking in pregnancy is harmful.

9/10/2017Maternal smoking may lead to cerebral palsy in offspring.

21/1/2022 Potent food supplement may help halt the immune attack in people with diabetes-Media release

Faculty of Medicine and Health

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Associate Professor Sonia Saad

Publications

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Selected Grants

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2021

2020

2018

2017

2016

2014

2009

2006

In the media