Dr Stephen Milne
Sydney Medical School
Westmead Clinical School
Faculty of Medicine and Health
Dr Stephen Milne is a specialist respiratory and sleep physician. After completing his clinical training, Dr Milne undertook PhD studies in respiratory physiology at the Woolcock Institute of Medical Research, Sydney, followed by a postdoctoral fellowship in lung -omics and biomarker discovery at the University of British Columbia, Vancouver.
Respiratory physiology
Chronic Obstructive Pulmonary Disease
Biomarkers
Respiratory medicine
Research
NH&MRC Postgraduate Research Scholarship, 2014
MITACS Accelerate fellowship, 2019
Publications
Journals
- Milne, S., Tonga, K., Eddy, R., Thompson, B., Thamrin, C., King, G. (2024). New physiological measurements in COPD. ERS Monograph, 2024 (103), 185-203. [More Information]
- Gerayeli, F., Park, H., Milne, S., Li, X., Yang, C., Tuong, J., Eddy, R., Vahedi, S., Guinto, E., Cheung, C., et al (2024). Single cell sequencing reveals cellular landscape alterations in the airway mucosa of patients with pulmonary long COVID. European Respiratory Journal, 64(5). [More Information]
- Milne, S. (2024). Testosterone and lung function: bigger lungs, slower decline or some combination of both? Thorax, 79(6), 493-494. [More Information]
Conferences
- McLennan, S., Jia, J., Milne, S., Lo, L., Bonner, J., Yue, D., Twigg, S. (2006). Propolis, the anti-inflammatory bee hive protectant improves wound healing in experimental diabetes. 42nd Annual Meeting of the European Association for the Study of Diabetes (EASD), Germany: Springer-Verlag.
2024
- Milne, S., Tonga, K., Eddy, R., Thompson, B., Thamrin, C., King, G. (2024). New physiological measurements in COPD. ERS Monograph, 2024 (103), 185-203. [More Information]
- Gerayeli, F., Park, H., Milne, S., Li, X., Yang, C., Tuong, J., Eddy, R., Vahedi, S., Guinto, E., Cheung, C., et al (2024). Single cell sequencing reveals cellular landscape alterations in the airway mucosa of patients with pulmonary long COVID. European Respiratory Journal, 64(5). [More Information]
- Milne, S. (2024). Testosterone and lung function: bigger lungs, slower decline or some combination of both? Thorax, 79(6), 493-494. [More Information]
2023
- Bates, J., Milne, S., Handley, B., Rutting, S., Chapman, D., King, G., Farah, C., Robinson, P., Thamrin, C. (2023). Model analysis of multiple breath nitrogen washout data: robustness to variations in breathing pattern. Journal of clinical monitoring and computing, 37(2), 409-420. [More Information]
- Guinto, E., Gerayeli, F., Eddy, R., Lee, H., Milne, S., Sin, D. (2023). Post-COVID-19 dyspnoea and pulmonary imaging: a systematic review and meta-analysis. European Respiratory Review, 32(169), 220253. [More Information]
- Gerayeli, F., Leung, J., Sin, D., Milne, S., Yang, C., Li, X., Guinto, E., Yang, J., Cheung, C., Stach, T., et al (2023). Single-cell RNA sequencing of bronchoscopy specimens: development of a rapid minimal handling protocol. BioTechniques, 75(4), 157-167. [More Information]
2022
- Ho, C., Milne, S., Li, X., Yang, C., Filho, F., Cheung, C., Yang, J., Cordero, A., Yang, C., Shaipanich, T., et al (2022). Airway Eosinophilia on Bronchoalveolar Lavage and the Risk of Exacerbations in COPD. Biomedicines, 10(6). [More Information]
- Choi, J., Milne, S., Yunus, F., Rhee, C., Matsunaga, K. (2022). Current Chronic Obstructive Pulmonary Disease Treatment Status in Asia: A Position Statement of the Asian Pacific Society of Respirology. Tuberculosis and Respiratory Diseases, 85(3), 279-282. [More Information]
- Yip, W., Li, X., Koelwyn, G., Milne, S., Filho, F., Yang, C., Cordero, A., Yang, J., Tony Yang, C., Shaipanich, T., et al (2022). Inhaled Corticosteroids Selectively Alter the Microbiome and Host Transcriptome in the Small Airways of Patients with Chronic Obstructive Pulmonary Disease. Biomedicines, 10(5), 1110. [More Information]
2021
- Handley, B., Jeagal, E., Schoeffel, R., Badal, T., Chapman, D., Farrow, C., King, G., Robinson, P., Milne, S., Thamrin, C. (2021). Controlled versus free breathing for multiple breath nitrogen washout in healthy adults. ERJ Open Research, 7(1), 435-2020. [More Information]
- Handley, B., Bozier, J., Jeagal, E., Rutting, S., Schoeffel, R., Robinson, P., King, G., Milne, S., Thamrin, C. (2021). Controlled versus free breathing for multiple-breath nitrogen washout in asthma. ERJ Open Research, 7(4), 00487-2021. [More Information]
- Gerayeli, F., Milne, S., Cheung, C., Li, X., Yang, C., Tam, A., Choi, L., Bae, A., Sin, D. (2021). COPD and the risk of poor outcomes in COVID-19: A systematic review and meta-analysis. EClinicalMedicine, 33, 100789. [More Information]
2020
- Milne, S., Mannino, D., Sin, D. (2020). Asthma-COPD Overlap and Chronic Airflow Obstruction: Definitions, Management, and Unanswered Questions. Journal of Allergy and Clinical Immunology: In Practice, 8(2), 483-495. [More Information]
- Milne, S., Sin, D. (2020). Biomarkers in Chronic Obstructive Pulmonary Disease: The Gateway to Precision Medicine. Clinics in Chest Medicine, 41(3), 383-394. [More Information]
- Hernandez Cordero, A., Li, X., Yang, C., Milne, S., Bossé, Y., Joubert, P., Timens, W., van den Berge, M., Nickle, D., Hao, K., et al (2020). Gene expression network analysis provides potential targets against SARS-CoV-2. Scientific Reports, 10(1), 21863. [More Information]
2019
- Sun, Y., Milne, S., Jaw, J., Yang, C., Xu, F., Li, X., Obeidat, M., Sin, D. (2019). BMI is associated with FEV1 decline in chronic obstructive pulmonary disease: A meta-analysis of clinical trials. Respiratory Research, 20(1), 236. [More Information]
- Milne, S., Jetmalani, K., Chapman, D., Duncan, J., Farah, C., Thamrin, C., King, G. (2019). Respiratory system reactance reflects communicating lung volume in chronic obstructive pulmonary disease. Journal of Applied Physiology, 126(5), 1223-1231. [More Information]
- Milne, S., Huvanandana, J., Nguyen, C., Duncan, J., Chapman, D., Tonga, K., Zimmermann, S., King, G., Slattery, A., Thamrin, C. (2019). Time-based pulmonary features from electrical impedance tomography demonstrate ventilation heterogeneity in chronic obstructive pulmonary disease. Journal of Applied Physiology, 127(5), 1441-1452. [More Information]
2018
- Milne, S., Hammans, C., Watson, S., Farah, C., Thamrin, C., King, G. (2018). Bronchodilator Responses in Respiratory Impedance, Hyperinflation and Gas Trapping in COPD. COPD: Journal of Chronic Obstructive Pulmonary Disease, 15(4), 341-349. [More Information]
2017
- Milne, S., Elkins, M. (2017). Exercise as an alternative treatment for chronic insomnia (PEDro synthesis). British Journal of Sports Medicine, 51(5), 478-479. [More Information]
2015
- Milne, S., King, G. (2015). Role of imaging in COPD phenotyping. Respirology, 20(4), 522-523. [More Information]
2014
- Milne, S., King, G. (2014). Advanced imaging in COPD: insights into pulmonary pathophysiology. Journal of Thoracic Disease, 6(11), 1570-1585. [More Information]
2008
- McLennan, S., Bonner, J., Milne, S., Lo, L., Charlton, A., Kurup, S., Jia, J., Yue, D., Twigg, S. (2008). The anti-inflammatory agent Propolis improves wound healing in a rodent model of experimental diabetes. Wound Repair and Regeneration, 16, 706-713. [More Information]
2006
- McLennan, S., Jia, J., Milne, S., Lo, L., Bonner, J., Yue, D., Twigg, S. (2006). Propolis, the anti-inflammatory bee hive protectant improves wound healing in experimental diabetes. 42nd Annual Meeting of the European Association for the Study of Diabetes (EASD), Germany: Springer-Verlag.
Further Publications
- Pavord, I. D., Holliday, M., Reddel, H. K., Braithwaite, I., Ebmeier, S., Hancox, R. J., Harrison, T., Houghton, C., Oldfield, K., Papi, A., Williams, M., Weatherall, M., Beasley, R., and the Novel START Study Team. (2020). Predictive value of blood eosinophils and exhaled nitric oxide in adults with mild asthma: a prespecified subgroup analysis of an open-label, parallel-group, randomised control trial. The Lancet Respiratory Medicine, 8(7), 671-680. [More Information]
- Beasley, R., Holliday, M., Reddel, H. K., Braithwaite, I., Ebmeier, S., Hancox, R. J., Harrison, T., Houghton, C., Oldfield, K., Papi, A., Pavord, I. D., Williams, M., Weatherall, M., and the Novel START Study Team. (2019). Controlled trial of Budesonide-Formoterol as needed for mild asthma. The New England Journal of Medicine, 380(21), 2020-2030. [More Information]
In the media
Explainer: What is Chronic Obstructive Pulmonary Disease?The Conversation [Published online 18 July 2014]
How Australians Die: cause #4 - chronic lower respiratory diseases The Conversation [Published online 9 June 2016]