Professor Andy Yong
Sydney Medical School
Concord Clinical School
Faculty of Medicine and Health
Associate Professor Andy YongMBBS, PhD, FRACP, FCSANZ is an interventional cardiologist and the Director of Coronary Physiology and Cardiac Measurement at Concord Hospital. He is an Associate Professor at the University of Sydney and Climical Associate Professor at Macquarie University. Having graduated with First Class Honours from the University of Sydney in 2002, Dr Yong undertook his residency and general cardiology training at Concord Hospital. He then trained as a research and interventional cardiology fellow at Royal Prince Alfred and Concord Hospitals, and was awarded a PhD degree in 2010. He subsequently completed a postdoctoral and clinical interventional cardiology fellowship at Stanford University Medical Center.
Clinical Interventional Cardiology
Translational Cardiovascular Research
Coronary Physiology
Computational Fluid Dynamics Analysis of Coronary Blood Flow
Platelet Activation
Current:
Clinical Supervisor: 2 Cardiology Advance Trainees, Concord Hospital
Concord Clinical School Cardiology Term Clinical Supervisor - 1 student per term
Co-supervisor for 2 Masters student
Primary supervisor for 1 Cardiology Research Fellow
Grants/Fellowships/Scholarships:
NHMRC Overseas Postdoctoral Training Fellowship (Neil-Hamilton) 2011-2014
RACP Foundation AstraZeneca Fellowship 2012
NHMRC Postgraduate Medical Scholarship 2008-2010
Pfizer CVL Grant 2010
NHF Travel Grant 2010
CSANZ Travel Grant 2009
Awards:
Peter Bancroft Prize (top ranked PhD in faculty of Medicine, USYD) 2011
Dean¿s Prize for best postgraduate publication, USYD 2010
Finalist Ralph Reader Prize (Cardiac Society) for best clinical research 2011
Concord Hospital Research Prize for best clinical research 2010
Finalist ANZET Fellows Prize for best abstract 2009
Best Year 1 Clinical Tutor Award, Concord Clinical School 2008
ConcordHospitalYoung Investigator Commendation Award 2007
(Stanford University, California, USA) Postdoctoral Fellow with ongoing collaborative efforts |
Publications
Book Chapters
- Javadzadegan, A., Behnia, M., Yong, A., Kritharides, L. (2013). Lesion Eccentricity and Fractional Flow Reserve and Coronary Flow Reserve in Coronary Arteries. In Andreas Ochsner, Holm Altenbach (Eds.), Advances in Bio-Mechanical Systems and Materials, (pp. 1-6). Cham: Springer. [More Information]
- Mohamed, A., Lal, S., Ho, J., Brown, A., Lui, R., Nguyen, L., Yong, A., Su, Y., Braet, F., Dyer, W., Junius, F., Cumming, R., Freedman, B., Kritharides, L., Dos Remedios, C. (2010). How to interrogate the cellular immune system in patients with ischemic heart disease. In Dmitry Vukovic & Vladimir Kiyan (Eds.), Myocardial ischemia: Causes, symptoms and treatment, (pp. 195-216). United States: Nova Science Publishers.
Journals
- Collet, C., Yong, A., Munhoz, D., Akasaka, T., Berry, C., Blair, J., Collison, D., Engstrøm, T., Escaned, J., Fearon, W., et al (2024). A Systematic Approach to the Evaluation of the Coronary Microcirculation Using Bolus Thermodilution: CATH CMD. Journal of the Society for Cardiovascular Angiography & Interventions, 3(7). [More Information]
- Celler, B., Yong, A., Rubenis, I., Butlin, M., Argha, A., Rehan, R., Aviolo, A. (2024). Accurate detection of Korotkoff sounds reveals large discrepancy between intra-arterial systolic pressure and simultaneous noninvasive measurement of blood pressure with brachial cuff sphygmomanometry. Journal of Hypertension, 42(5), 873-882. [More Information]
- Celler, B., Yong, A., Rubenis, I., Butlin, M., Argha, A., Rehan, R., Aviolo, A. (2024). Comparison of cuff inflation and cuff deflation brachial sphygmomanometry with intra-arterial blood pressure as reference. Journal of Hypertension, 42(6), 968-976. [More Information]
Conferences
- Javadzadegan, A., Yong, A., Chang, M., MANSOUR, N., Ng, M., Behnia, M., Kritharides, L. (2012). Comparison of Four Different Fluid Structure Interaction Models in a Human Coronary Artery. 18th Australasian Fluid Mechanics Conference AFMC 2012, Launceston, Tasmania: Australasian Fluid Mechanics Society.
2024
- Collet, C., Yong, A., Munhoz, D., Akasaka, T., Berry, C., Blair, J., Collison, D., Engstrøm, T., Escaned, J., Fearon, W., et al (2024). A Systematic Approach to the Evaluation of the Coronary Microcirculation Using Bolus Thermodilution: CATH CMD. Journal of the Society for Cardiovascular Angiography & Interventions, 3(7). [More Information]
- Celler, B., Yong, A., Rubenis, I., Butlin, M., Argha, A., Rehan, R., Aviolo, A. (2024). Accurate detection of Korotkoff sounds reveals large discrepancy between intra-arterial systolic pressure and simultaneous noninvasive measurement of blood pressure with brachial cuff sphygmomanometry. Journal of Hypertension, 42(5), 873-882. [More Information]
- Celler, B., Yong, A., Rubenis, I., Butlin, M., Argha, A., Rehan, R., Aviolo, A. (2024). Comparison of cuff inflation and cuff deflation brachial sphygmomanometry with intra-arterial blood pressure as reference. Journal of Hypertension, 42(6), 968-976. [More Information]
2023
- Noaman, S., Kaye, D., Nanayakkara, S., Dart, A., Yong, A., Ng, M., Vizi, D., Duffy, S., Cox, N., Chan, W. (2023). Haemodynamic and metabolic adaptations in coronary microvascular disease. Heart. [More Information]
- Koo, B., Lee, J., Hwang, D., Park, S., Shiono, Y., Yonetsu, T., Lee, S., Kawase, Y., Ahn, J., Matsuo, H., Yong, A., et al (2023). Practical Application of Coronary Physiologic Assessment: Asia-Pacific Expert Consensus Document: Part 1. JACC: Asia, 3(5), 689-706. [More Information]
- Koo, B., Hwang, D., Park, S., Kuramitsu, S., Yonetsu, T., Kim, C., Zhang, J., Yang, S., Doh, J., Jeong, Y., Yong, A., et al (2023). Practical Application of Coronary Physiologic Assessment: Asia-Pacific Expert Consensus Document: Part 2. JACC: Asia, 3(6), 825-842. [More Information]
2022
- Rehan, R., Weaver, J., Yong, A. (2022). Coronary Vasospastic Angina: A Review of the Pathogenesis, Diagnosis, and Management. Life, 12(8). [More Information]
- Wong, C., Javadzadegan, A., Cuneyt, A., Lau, J., Bhindi, R., Fearon, W., Kritharides, L., Ng, M., Yong, A. (2022). Fractional Flow Reserve and Instantaneous Wave-Free Ratio Predict Pathological Wall Shear Stress in Coronary Arteries: Implications for Understanding the Pathophysiological Impact of Functionally Significant Coronary Stenoses. Journal of the American Heart Association, 11(3), e023502. [More Information]
- Rehan, R., Kempler, E., McMaster, K., Larnach, G., Amos, D., Elder, A., Arnold, R., Juergens, C., Patel, S., Weaver, J., Ng, M., Roy, P., Yong, A., Brieger, D., Kritharides, L., Adams, M., Lowe, H. (2022). In Hospital Outcomes for High-Risk Percutaneous Coronary Intervention (PCI) in Patients Referred From a Rural Centre to Metropolitan Sites. Heart, Lung, and Circulation, 31(2), 224-229. [More Information]
2021
- Wong, C., Ng, A., Ada, C., Chow, V., Fearon, W., Ng, M., Kritharides, L., Yong, A. (2021). A real-world comparison of outcomes between fractional flow reserve-guided versus angiography-guided percutaneous coronary intervention. PloS One, 16(44907), e0259662. [More Information]
- Yong, A., Pargaonkar, V., Wong, C., Javadzdegan, A., Yamada, R., Tanaka, S., Kimura, T., Rogers, I., Sen, I., Kritharides, L., et al (2021). Abnormal shear stress and residence time are associated with proximal coronary atheroma in the presence of myocardial bridging. International Journal of Cardiology, 340, 7-13. [More Information]
- Celler, B., Butlin, M., Argha, A., Tan, I., Yong, A., Avolio, A. (2021). Are Korotkoff Sounds Reliable Markers for Accurate Estimation of Systolic and Diastolic Pressure Using Brachial Cuff Sphygmomanometry? IEEE Transactions on Biomedical Engineering, 68(12), 3593-3601. [More Information]
2020
- Tong, D., Quinn, S., Nasis, A., Hiew, C., Roberts-Thomson, P., Adams, H., Sriamareswaran, R., Htun, N., Wilson, W., Stub, D., et al (2020). Colchicine in Patients With Acute Coronary Syndrome: The Australian COPS Randomized Clinical Trial. Circulation, 142(20), 1890-1900. [More Information]
- Lo, S., Yong, A., Sinhal, A., Shetty, S., McCann, A., Clark, D., Galligan, L., El-Jack, S., Sader, M., Tan, R., Bhindi, R., Kritharides, L., et al (2020). Consensus Guidelines for Interventional Cardiology Services Delivery During COVID-19 Pandemic in Australia and New Zealand. Heart, Lung, and Circulation, 29(6), e69-e77. [More Information]
- Wong, C., Yong, A. (2020). Flash-Forward: The Emergence of Angiography-Derived Fractional Flow Reserve in the Catheter Laboratory. Cardiovascular Research, 116(7), 1242-1245. [More Information]
2019
- Lee, H., Lee, J., Nam, C., Shin, E., Doh, J., Dai, N., Ng, M., Yong, A., Tresukosol, D., Mullasari, A., et al (2019). Consensus document for invasive coronary physiologic assessment in Asia-Pacific countries. Cardiology Journal, 26(3), 215-225. [More Information]
- Javadzadegan, A., Moshfegh, A., Qian, Y., Kritharides, L., Yong, A. (2019). Myocardial bridging and endothelial dysfunction - Computational fluid dynamics study. Journal of Biomechanics, 85, 92-100. [More Information]
- Nishi, T., Murai, T., Ciccarelli, G., Shah, S., Kobayashi, Y., Derimay, F., Waseda, K., Moonen, A., Hoshino, M., Hirohata, A., Yong, A., Ng, M., et al (2019). Prognostic Value of Coronary Microvascular Function Measured Immediately After Percutaneous Coronary Intervention in Stable Coronary Artery Disease: An International Multicenter Study. Circulation: Cardiovascular Interventions, 12(9), 1-8. [More Information]
2018
- Ihdayhid, A., Yong, A., Harper, R., Rankin, J., Wong, C., Brown, A., Leung, M., Ko, B. (2018). A Practical Guide for Fractional Flow Reserve Guided Revascularisation. Heart, Lung, and Circulation, 27(4), 406-419. [More Information]
- Yong, A., Fearon, W. (2018). Assessing the Coronary Microcirculation in Patients After Primary Percutaneous Coronary Intervention. Journal of the American Heart Association, 7(15), 1-3. [More Information]
- Wu, J., Way, J., Roy, P., Yong, A., Lowe, H., Kritharides, L., Brieger, D. (2018). Biodegradable polymer versus second-generation durable polymer drug-eluting stents in patients with coronary artery disease: A meta-analysis. Health Science Reports, 1(11), 1-10. [More Information]
2017
- Lau, J., Pennings, G., Yong, A., Kritharides, L. (2017). Cardiac Remote Ischaemic Preconditioning: Mechanistic and Clinical Considerations. Heart, Lung, and Circulation, 26(6), 545-553. [More Information]
- Javadzadegan, A., Yong, A., Chang, M., Ng, M., Behnia, M., Kritharides, L. (2017). Haemodynamic assessment of human coronary arteries is affected by degree of freedom of artery movement. Computer Methods in Biomechanics and Biomedical Engineering, 20(3), 260-272. [More Information]
- Ford, T., Berry, C., De Bruyne, B., Yong, A., Barlis, P., Fearon, W., Ng, M. (2017). Physiological Predictors of Acute Coronary Syndromes: Emerging Insights From the Plaque to the Vulnerable Patient. J A C C: Cardiovascular Interventions, 10(24), 2539-2547. [More Information]
2016
- Wong, C., Ng, A., Lau, J., Chow, V., Chen, V., Ng, A., Yong, A., Sindone, A., Marwick, T., Kritharides, L. (2016). High mortality in patients presenting with acute pulmonary embolism and elevated INR not on anticoagulant therapy. Thrombosis and Haemostasis, 115(6), 1191-1199. [More Information]
- Jin, X., Lim, H., Tahk, S., Yang, H., Yoon, M., Choi, S., Choi, B., Yong, A., Fearon, W., Sheen, S., et al (2016). Impact of age on the functional significance of intermediate Epicardial artery disease. Circulation Journal, 80(7), 1583-1589. [More Information]
- Ng, A., Adikari, D., Yuan, D., Lau, J., Yong, A., Chow, V., Kritharides, L. (2016). The Prevalence and Incidence of Atrial Fibrillation in Patients with Acute Pulmonary Embolism. PloS One, 11(3), 1-14. [More Information]
2015
- Bing, R., Yong, A., Fearon, W. (2015). Assessment of left main artery stenosis with fractional flow reserve is affected by downstream stenosis in the left anterior descending artery. Coronary Artery Disease, 26(Suppl 1), e35-e37. [More Information]
- Lee, J., Layland, J., Jung, J., Lee, H., Echavarria-Pinto, M., Watkins, S., Yong, A., Doh, J., Nam, C., Shin, E., Ng, M., et al (2015). Integrated Physiologic Assessment of Ischemic Heart Disease in Real-World Practice Using Index of Microcirculatory Resistance and Fractional Flow Reserve: Insights From the International Index of Microcirculatory Resistance Registry. Circulation: Cardiovascular Interventions, 8(11), 1-13. [More Information]
- Lee, B., Lim, H., Fearon, W., Yong, A., Yamada, R., Tanaka, S., Lee, D., Yeung, A., Tremmel, J. (2015). Invasive evaluation of patients with angina in the absence of obstructive coronary artery disease. Circulation, 131(12), 1054-1060. [More Information]
2014
- Moutzouris, J., Chow, V., Yong, A., Chung, T., Naganathan, V., Kritharides, L., Ng, A. (2014). Acute Pulmonary Embolism in Individuals Aged 80 and Older. Journal of the American Geriatrics Society, 62(10), 2004-2006. [More Information]
- Pennings, G., Yong, A., Wong, C., Al-Tamimi, M., Gardiner, E., Andrews, R., Kritharides, L. (2014). Circulating levels of soluble EMMPRIN (CD147) correlate with levels of soluble glycoprotein VI in human plasma. Platelets, 25(8), 639-642. [More Information]
- Pennings, G., Siegwald, J., Yong, A., Kritharides, L., Lowe, H. (2014). Intravascular blood sampling using the thrombuster II catheter does not cause artifactual platelet activation. Journal of Thrombosis and Thrombolysis, 37(3), 326-330. [More Information]
2013
- Alcock, R., Yong, A., Ng, A., Chow, V., Cheruvu, C., Aliprandi-Costa, B., Lowe, H., Kritharides, L., Brieger, D. (2013). Acute coronary syndrome and stable coronary artery disease: Are they so different? Long-term outcomes in a contemporary PCI cohort. International Journal of Cardiology, 167(4), 1343-1346. [More Information]
- Yong, A., Layland, J., Fearon, W., Ho, M., Shah, M., Daniels, D., Whitbourn, R., MacIsaac, A., Kritharides, L., Wilson, A., Ng, M. (2013). Calculation of the index of microcirculatory resistance without coronary wedge pressure measurement in the presence of epicardial stenosis. JACC: Cardiovascular Interventions, 6(1), 53-58. [More Information]
- Yong, A., Tremmel, J. (2013). Can We Bear Another Bare-Metal Stent Study? Catheterization and Cardiovascular Interventions, 81, 1095-1096. [More Information]
2012
- Javadzadegan, A., Yong, A., Chang, M., MANSOUR, N., Ng, M., Behnia, M., Kritharides, L. (2012). Comparison of Four Different Fluid Structure Interaction Models in a Human Coronary Artery. 18th Australasian Fluid Mechanics Conference AFMC 2012, Launceston, Tasmania: Australasian Fluid Mechanics Society.
- Yong, A., Ho, M., Shah, M., Ng, M., Fearon, W. (2012). Coronary Microcirculatory Resistance is Independent of Epicardial Stenosis. Circulation: Cardiovascular Interventions, 5(1), 103-108. [More Information]
- Alcock, R., Yong, A., Yiannikas, J., Lowe, H. (2012). Optical coherence tomography-guided left main stem stenting: A new approach? Texas Heart Institute Journal, 39(4), 596-597. [More Information]
2011
- Moharram, M., Yong, A., Khoury, V., Lowe, H. (2011). Arriving Safely and Avoiding a Puncture: Use of a Radi PressureWire to Cross an ATS Prosthetic Aortic Valve for Direct Measurement of Left Ventricular Pressure. Texas Heart Institute Journal, 38(1), 50-51. [More Information]
- Yong, A., Pennings, G., Chang, M., Hamzah, A., Chung, T., Qi, M., Brieger, D., Behnia, M., Krilis, S., Ng, M., Lowe, H., Kritharides, L. (2011). Intracoronary Shear-Related Up-Regulation of Platelet P-Selectin and Platelet-Monocyte Aggregation Despite the Use of Aspirin and Clopidogrel. Blood, 117(1), 11-20. [More Information]
- Ng, A., Chung, T., Yong, A., Wong, H., Chow, V., Celermajer, D., Kritharides, L. (2011). Long-Term Cardiovascular and Noncardiovascular Mortality of 1023 Patients With Confirmed Acute Pulmonary Embolism. Circulation: Cardiovascular Quality and Outcomes, 4(1), 122-128. [More Information]
2010
- Ng, A., Yiannikas, J., Yong, A., Ridley, L., Wilson, M., Kritharides, L. (2010). Coronary ostial morphology after modified Bentall operation assessed with dual-source multidetector computed tomography. Journal of Cardiovascular Computed Tomography, 4(3), 206-212. [More Information]
- Pennings, G., Yong, A., Kritharides, L. (2010). Expression of EMMPRIN (CD147) on circulating platelets in vivo. Journal of Thrombosis and Haemostasis, 8(3), 472-481. [More Information]
- Mohamed, A., Lal, S., Ho, J., Brown, A., Lui, R., Nguyen, L., Yong, A., Su, Y., Braet, F., Dyer, W., Junius, F., Cumming, R., Freedman, B., Kritharides, L., Dos Remedios, C. (2010). How to interrogate the cellular immune system in patients with ischemic heart disease. In Dmitry Vukovic & Vladimir Kiyan (Eds.), Myocardial ischemia: Causes, symptoms and treatment, (pp. 195-216). United States: Nova Science Publishers.
2009
- Yong, A., Pennings, G., Chung, T., Brieger, D., Lowe, H., Kritharides, L. (2009). Intravascular Blood Sampling Using the Export Catheter Does Not Induce Artifactual Platelet Activation. Journal of Invasive Cardiology, 21(4), 159-161. [More Information]
- Yong, A., Lowe, H., Ng, M., Kritharides, L. (2009). The Intracoronary Electrocardiogram in Percutaneous Coronary Intervention. Journal of Interventional Cardiology, 22(1), 68-76. [More Information]
2007
- Yong, A., Wyndham, R., Lowe, H. (2007). When ballooning alone is enough: Successful treatment of hypertension secondary to renal artery fibromuscular dysplasia using angioplasty. International Journal of Cardiology, 131, e85-6. [More Information]
2006
- Ng, A., Wong, H., Yong, A., Sindone, A. (2006). Impact of gender on outcomes in chronic systolic heart failure. International Journal of Cardiology, 0, 1-8. [More Information]
Selected Grants
2017
- RES: The effect of coronary microvascular function and shear stress on cardiac allograft vasculopathy - Abbott Australia Pty Ltd - Martin Ng, Ng M, Yong A, Abbott Australasia Pty Ltd/Investigator Sponsored Study (ISS)
- Restoring Microcirculatory Perfusion in ST-elevation Myocardial Infarction: The RESTORE MI study, Ng M, Fearon W, Yong A, Keech A, White H, Layland J, National Health and Medical Research Council (NHMRC)/Project Grants
2011
- Studying Coronary Physiology within Human Coronary Arteries using Computational Fluid Dynamics, Yong A, National Health and Medical Research Council (NHMRC)/Early Career Fellowships