Dr Ting Zhang
People_

Dr Ting Zhang

Postdoctoral Research Associate
Faculty of Medicine and Health
Clinical Ophthalmology and Eye Health
Save Sight Institute
Project titleResearch student
Investigating the Structure-Interaction Relationship of Human Proton-Coupled Oligopeptide Transporter (hPepT2) and NucleotidesKimberly CO
Determine the Mechanism of Novel Human Uveal Melanoma (UM) Lead MoleculesAlex JIN
NRF2/MAFF RNA-based drug delivered by lipid nanoparticles for treating macular degenerationJialing ZHANG

Publications

Book Chapters

  • Zhang, T., Bahrami, B., Zhu, L. (2018). Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retina. In Alexzander A. A. Asea, Punit Kaur (Eds.), HSP70 in human diseases and disorders, (pp. 273-287). Cham: Springer. [More Information]

Journals

  • Zhang, T., Wang, L., Gu, J., Xu, J., Chen, W., Huang, Y., Hong, J., Wang, T., Li, S., Gao, H., et al (2023). A multicenter clinical trial of collar‑button type keratoprosthesis implantation for the treatment of corneal blindness in high‑risk transplantation. Zhonghua Yanke Zazhi, 59(4), 262-271. [More Information]
  • Yuan, W., Liu, T., Wang, Y., He, S., Zhang, F., Wang, X., Deng, S., Zhang, T., Wu, D., Xu, Y. (2023). Autophagy induced by PP121 alleviates MSU crystal-induced acute gouty arthritis via inhibition of the NLRP3 inflammasome. International Immunopharmacology, 123. [More Information]
  • Zhang, T., Liu, M., Xie, G., Wu, D., Luo, P., Liu, T., Deng, S., Wang, Y., He, S., Zhou, Y., et al (2023). CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway. Journal of Cancer, 14(8), 1350-1361. [More Information]

2023

  • Zhang, T., Wang, L., Gu, J., Xu, J., Chen, W., Huang, Y., Hong, J., Wang, T., Li, S., Gao, H., et al (2023). A multicenter clinical trial of collar‑button type keratoprosthesis implantation for the treatment of corneal blindness in high‑risk transplantation. Zhonghua Yanke Zazhi, 59(4), 262-271. [More Information]
  • Yuan, W., Liu, T., Wang, Y., He, S., Zhang, F., Wang, X., Deng, S., Zhang, T., Wu, D., Xu, Y. (2023). Autophagy induced by PP121 alleviates MSU crystal-induced acute gouty arthritis via inhibition of the NLRP3 inflammasome. International Immunopharmacology, 123. [More Information]
  • Zhang, T., Liu, M., Xie, G., Wu, D., Luo, P., Liu, T., Deng, S., Wang, Y., He, S., Zhou, Y., et al (2023). CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway. Journal of Cancer, 14(8), 1350-1361. [More Information]

2022

  • Zhang, T., Deng, R., Wang, Y., Wu, C., Zhang, K., Wang, C., Gong, N., Ledesma-Amaro, R., Teng, X., Yang, C., et al (2022). A paper-based assay for the colorimetric detection of SARS-CoV-2 variants at single-nucleotide resolution. Nature Biomedical Engineering, 6(8), 957-967. [More Information]
  • Wu, D., Li, J., Shen, R., Li, J., Yu, Y., Li, L., Deng, S., Liu, T., Zhang, T., Xu, Y., et al (2022). Autophagy Induced by Micheliolide Alleviates Acute Irradiation-Induced Intestinal Injury via Inhibition of the NLRP3 Inflammasome. Frontiers in Pharmacology, 12. [More Information]
  • Song, W., Jia, P., Zhang, T., Dou, K., Liu, L., Ren, Y., Liu, F., Xue, J., Hasanin, M., Qi, H., et al (2022). Cell membrane-camouflaged inorganic nanoparticles for cancer therapy. Journal of Nanobiotechnology, 20(1). [More Information]

2021

  • Chi, H., Hao, W., Qi, X., Zhang, T., Dong, Y., Gao, H., Wei, C., Shi, W. (2021). A proteomic approach towards understanding the pathogenesis of Mooren's ulcer. Experimental Eye Research, 205. [More Information]
  • He, M., Wu, D., Zhao, Y., Yu, Y., Deng, S., Liu, T., Zhang, T., Li, J., Wang, F., Xu, Y. (2021). AZD8055 ameliorates experimental autoimmune encephalomyelitis via the mTOR/ROS/NLRP3 pathway. Biochemical and Biophysical Research Communications, 573, 27-34. [More Information]
  • Li, H., Chen, M., Zhou, Q., Pan, X., Cheng, J., Cong, L., Zhang, T., Dong, Y., Xie, L. (2021). Biomechanical effects of deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: A finite element analysis. Translational Vision Science and Technology, 10(9). [More Information]

2020

  • Zheng, X., Zheng, X., Zheng, X., Yang, X., Yang, X., Wan, J., Wan, J., Zhang, T., Zhang, T., Yang, Z., et al (2020). A novel super thermal insulation material: Bamboo-like polymer nanotubes. Nanotechnology, 31(34). [More Information]
  • Wu, D., Liu, T., Deng, S., Han, R., Zhang, T., Li, J., Xu, Y. (2020). Alpha-1 antitrypsin induces epithelial-to-mesenchymal transition, endothelial-to-mesenchymal transition, and drug resistance in lung cancer cells. OncoTargets and Therapy, 13, 3751-3763. [More Information]
  • Li, J., Wu, D., Yu, Y., Deng, S., Liu, T., Zhang, T., He, M., Zhao, Y., Xu, Y. (2020). Amifostine ameliorates induction of experimental autoimmune encephalomyelitis: Effect on reactive oxygen species/NLRP3 pathway. International Immunopharmacology, 88. [More Information]

2019

  • Cheng, Z., Yao, W., Zheng, J., Ding, W., Wang, Y., Zhang, T., Zhu, L., Zhou, F. (2019). A derivative of betulinic acid protects human Retinal Pigment Epithelial (RPE) cells from cobalt chloride-induced acute hypoxic stress. Experimental Eye Research, 180, 92-101. [More Information]
  • Lukowski, S., Lo, C., Sharov, A., Nguyen, Q., Fang, L., Hung, S., Zhu, L., Zhang, T., Grunert, U., Nguyen, T., Gillies, M., et al (2019). A single-cell transcriptome atlas of the adult human retina. EMBO Journal, 38(18), 1-15. [More Information]
  • Cheng, Z., Zhang, T., Zheng, J., Ding, W., Wang, Y., Li, Y., Zhu, L., Murray, M., Zhou, F. (2019). Betulinic acid derivatives can protect human Muller cells from glutamate-induced oxidative stress. Experimental Cell Research, 383(1), 1-8. [More Information]

2018

  • Shen, W., Lee, S., Yam, M., Zhu, L., Zhang, T., Pye, V., Mathai, A., Shibagaki, K., Zhang, J., Matsugi, T., Gillies, M. (2018). A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Muller Cell Disruption. Investigative Ophthalmology and Visual Science, 59(15), 6075-6088. [More Information]
  • Zhu, G., Lu, B., Zhang, T., Zhang, T., Zhang, C., Li, Y., Peng, Q. (2018). Antibiofilm effect of drug-free and cationic poly(D,L-lactide-co-glycolide) nanoparticles via nano-bacteria interactions. Nanomedicine, 13(10), 1093-1106. [More Information]
  • Zhu, L., Shen, W., Zhang, T., Wang, Y., Bahrami, B., Zhou, F., Gillies, M. (2018). Characterization of canonical Wnt signalling changes after induced disruption of Muller cell in murine retina. Experimental Eye Research, 175, 173-180. [More Information]

2017

  • Zhang, T., Zhang, J., Sun, X., Tian, J., Shi, W., Yuan, G. (2017). Early vitrectomy for dense vitreous hemorrhage in adults with non-traumatic and non-diabetic retinopathy. Journal of international medical research, 45(6), 2065-2071. [More Information]
  • Zhang, J., Yuan, G., Dong, M., Zhang, T., Hua, G., Zhou, Q., Shi, W. (2017). Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-to-mesenchymal transition. Histochemistry and Cell Biology, 147(3), 367-375. [More Information]
  • Zhang, T., Luo, J., Fu, Y., Li, H., Ding, R., Gong, T., Zhang, Z. (2017). Novel oral administrated paclitaxel micelles with enhanced bioavailability and antitumor efficacy for resistant breast cancer. Colloids And Surfaces B: Biointerfaces, 150, 89-97. [More Information]

2016

  • Luo, J., Zhang, T., Zhang, Q., Cao, X., Zeng, X., Fu, Y., Zhang, Z., Gong, T. (2016). A novel injectable phospholipid gel co-loaded with doxorubicin and bromotetrandrine for resistant breast cancer treatment by intratumoral injection. Colloids And Surfaces B: Biointerfaces, 140, 538-547. [More Information]
  • Zhang, T., Wang, Y., Jia, Y., Liu, D., Li, S., Shi, W., Gao, H. (2016). Active Pedicle Epithelial Flap Transposition Combined with Amniotic Membrane Transplantation for Treatment of Nonhealing Corneal Ulcers. Journal of Ophthalmology, 2016. [More Information]
  • Li, Y., Liu, Q., Li, W., Zhang, T., Li, H., Li, R., Chen, L., Pu, S., Kuang, J., Su, Z., et al (2016). Design and Validation of PEG-Derivatized Vitamin E Copolymer for Drug Delivery into Breast Cancer. Bioconjugate Chemistry, 27(8), 1889-1899. [More Information]

2015

  • Zhang, T., Peng, Q., San, F., Luo, J., Wang, M., Wu, W., Gong, T., Zhang, Z. (2015). A high-efficiency, low-toxicity, phospholipids-based phase separation gel for long-term delivery of peptides. Biomaterials, 45, 1-9. [More Information]
  • Zhang, J., Chu, S., Sun, X., Zhang, T., Shi, W. (2015). Bevacizumab modulates retinal pigment epithelial-to- mesenchymal transition via regulating Notch signaling. International Journal of Ophthalmology, 8(2), 245-249. [More Information]
  • Peng, Q., Wei, X., Yang, Q., Zhang, S., Zhang, T., Shao, X., Cai, X., Zhang, Z., Lin, Y. (2015). Enhanced biostability of nanoparticle-based drug delivery systems by albumin corona. Nanomedicine, 10(2), 205-214. [More Information]

2014

  • Sai, H., Xing, L., Xiang, J., Cui, L., Jiao, J., Zhao, C., Li, Z., Li, F., Zhang, T. (2014). Flexible aerogels with interpenetrating network structure of bacterial cellulose-silica composite from sodium silicate precursor via freeze drying process. RSC Advances, 4(57), 30453-30461. [More Information]
  • Zhang, T., Xie, X., Cao, G., Jiang, H., Wu, S., Su, Z., Zhang, K., Lu, F. (2014). Malattia leventinese/doyne honeycomb retinal dystrophy in a Chinese family with mutation of the EFEMP1 gene. Retina, 34(12), 2462-2471. [More Information]
  • Peng, Q., Wei, X., Shao, X., Zhang, T., Zhang, S., Fu, N., Cai, X., Zhang, Z., Lin, Y. (2014). Nanocomplex based on biocompatible phospholipids and albumin for long-circulation applications. ACS Applied Materials and Interfaces, 6(16), 13730-13737. [More Information]

2013

  • Zhang, T., Zheng, Y., Peng, Q., Cao, X., Gong, T., Zhang, Z. (2013). A novel submicron emulsion system loaded with vincristine-oleic acid ion-pair complex with improved anticancer effect: In vitro and in vivo studies. International Journal of Nanomedicine, 8, 1185-1196. [More Information]
  • Jiang, H., Huang, X., Su, Z., Rao, L., Wu, S., Zhang, T., Li, K., Quan, Q., Zhang, K. (2013). Genetic analysis of the forkhead transcriptional factor 2 gene in three Chinese families with blepharophimosis syndrome. Molecular Vision, 19, 418-423.
  • Peng, Q., Sun, X., Gong, T., Wu, C., Zhang, T., Tan, J., Zhang, Z. (2013). Injectable and biodegradable thermosensitive hydrogels loaded with PHBHHx nanoparticles for the sustained and controlled release of insulin. Acta Biomaterialia, 9(2), 5063-5069. [More Information]

Selected Grants

2022

  • Targeting Nrf2-MAFF pathway in Mller cells to treat macula degeneration, Zhu L, Gilles M, Zhang T, Ophthalmic Research Institute of Australia (ORIA)/ORIA Grant

2021

  • Activating endogenous phosphoglycerate dehydrogenase (PHGDH) to treat age-related macular degeneration with the help of a Muller cell-specific lipid nanocarrier, Zhang T, Gillies M, Chrzanowski W, Macular Disease Foundation Australia/Research Grant