People_
Dr Ting Zhang
Postdoctoral Research Associate
Faculty of Medicine and Health
Clinical Ophthalmology and Eye Health
Save Sight Institute
Faculty of Medicine and Health
Clinical Ophthalmology and Eye Health
Save Sight Institute
Email
Websites
Project title | Research student |
---|---|
Investigating the Structure-Interaction Relationship of Human Proton-Coupled Oligopeptide Transporter (hPepT2) and Nucleotides | Kimberly CO |
Determine the Mechanism of Novel Human Uveal Melanoma (UM) Lead Molecules | Alex JIN |
NRF2/MAFF RNA-based drug delivered by lipid nanoparticles for treating macular degeneration | Jialing ZHANG |
Publications
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Book Chapters
- Zhang, T., Bahrami, B., Zhu, L. (2018). Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retina. In Alexzander A. A. Asea, Punit Kaur (Eds.), HSP70 in human diseases and disorders, (pp. 273-287). Cham: Springer. [More Information]
Journals
- Zhang, T., Wang, L., Gu, J., Xu, J., Chen, W., Huang, Y., Hong, J., Wang, T., Li, S., Gao, H., et al (2023). A multicenter clinical trial of collar‑button type keratoprosthesis implantation for the treatment of corneal blindness in high‑risk transplantation. Zhonghua Yanke Zazhi, 59(4), 262-271. [More Information]
- Yuan, W., Liu, T., Wang, Y., He, S., Zhang, F., Wang, X., Deng, S., Zhang, T., Wu, D., Xu, Y. (2023). Autophagy induced by PP121 alleviates MSU crystal-induced acute gouty arthritis via inhibition of the NLRP3 inflammasome. International Immunopharmacology, 123. [More Information]
- Zhang, T., Liu, M., Xie, G., Wu, D., Luo, P., Liu, T., Deng, S., Wang, Y., He, S., Zhou, Y., et al (2023). CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway. Journal of Cancer, 14(8), 1350-1361. [More Information]
- Dai, M., Peng, W., Lin, L., Wu, Z., Zhang, T., Zhao, Q., Cheng, Y., Lin, Q., Zhang, B., Liu, A., et al (2023). Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii. Phytomedicine, 121. [More Information]
- Zhang, T., Wei, C., Wu, X., Zhang, S., Duan, F., Qi, X., Shi, W., Gao, H. (2023). Characterization and Evaluation of Rapamycin-Loaded Nano-Micelle Ophthalmic Solution. Journal of Functional Biomaterials, 14(1). [More Information]
- Rao, Q., Zhang, T., Pu, Q., Li, B., Zhao, Q., Yan, D., Wu, Z., Li, F. (2023). Comparative metabolism of THCA and THCV using UHPLC-Q-Exactive Orbitrap-MS. Xenobiotica, 53(1), 46-59. [More Information]
- Wang, Y., Zhang, T., Du, H., Yang, M., Xie, G., Liu, T., Deng, S., Yuan, W., He, S., Wu, D., et al (2023). Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin. Oncology Reports, 50(2). [More Information]
- Li, X., Zhang, J., Chen, Q., Tang, P., Zhang, T., Feng, Q., Chen, J., Liu, Y., Wang, F., Peng, C., et al (2023). Diversity-oriented synthesis of diterpenoid alkaloids yields a potent anti-inflammatory agent. Phytomedicine, 117. [More Information]
- Li, Y., Zhang, T., Zhang, J., Liu, Q., Jia, Q., Chen, W., Tang, Q., Xiong, Y., Xia, Y., Xu, Y., et al (2023). Dually fibronectin/CD44-mediated nanoparticles targeted disrupt the Golgi apparatus and inhibit the hedgehog signaling in activated hepatic stellate cells to alleviate liver fibrosis. Biomaterials, 301. [More Information]
- Wu, M., Liu, Y., Zhao, Y., Zhang, Y., Huang, L., Du, Q., Zhang, T., Zhong, Z., Luo, H., Xiao, K. (2023). Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma. Journal of Visualized Experiments, 2023 (196). [More Information]
- Huang, Y., Bao, T., Zhang, T., Ji, G., Wang, Y., Ling, Z., Li, W. (2023). Machine Learning Study of SNPs in Noncoding Regions to Predict Non-small Cell Lung Cancer Susceptibility. Clinical Oncology, 35(11), 701-712. [More Information]
- Zhang, T., Bao, L., Zhao, Q., Wu, Z., Dai, M., Rao, Q., Li, F. (2023). Metabolomics Reveals Gut Microbiota Contribute to PPARα Deficiency-Induced Alcoholic Liver Injury. Journal of Proteome Research, 22(7), 2327-2338. [More Information]
- Sun, Y., Zeng, F., Zhang, J., Qi, X., Lu, X., Ning, N., Li, S., Zhang, T., Yuan, G., Shi, W., et al (2023). Microbiological Characteristics and Risk Factors Involved in Progression from Fungal Keratitis with Hypopyon to Keratitis-Related Endophthalmitis. Mycopathologia, 188(5), 805-813. [More Information]
- Zhao, Q., Dai, M., Huang, R., Duan, J., Zhang, T., Bao, W., Zhang, J., Gui, S., Xia, S., Dai, C., et al (2023). Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice. Nature Communications, 14(1). [More Information]
- Zhang, T., Zeng, Q., Ji, F., Wu, H., Ledesma-Amaro, R., Wei, Q., Yang, H., Xia, X., Ren, Y., Mu, K., et al (2023). Precise in-field molecular diagnostics of crop diseases by smartphone-based mutation-resolved pathogenic RNA analysis. Nature Communications, 14(1). [More Information]
- Deng, S., Li, J., Li, L., Lin, S., Yang, Y., Liu, T., Zhang, T., Xie, G., Wu, D., Xu, Y. (2023). Quercetin alleviates lipopolysaccharide‑induced acute lung injury by inhibiting ferroptosis via the Sirt1/Nrf2/Gpx4 pathway. International Journal of Molecular Medicine, 52(6). [More Information]
- Zeng, S., Chen, Y., Zhou, F., Zhang, T., Fan, X., Chrzanowski, W., Gillies, M., Zhu, L. (2023). Recent advances and prospects for lipid-based nanoparticles as drug carriers in the treatment of human retinal diseases. Advanced Drug Delivery Reviews, 199, 114965. [More Information]
- Zhang, J., Zhang, T., Zeng, S., Zhang, X., Zhou, F., Gillies, M., Zhu, L. (2023). The Role of Nrf2/sMAF Signalling in Retina Ageing and Retinal Diseases. Biomedicines, 11(6), 1512. [More Information]
- Zhang, T., Xie, L., Dong, Y., Cheng, J. (2023). Therapeutic keratoplasty for severe Acanthamoeba keratitis: risk factors, clinical features, and outcomes of postoperative recurrence. Graefe's Archive for Clinical and Experimental Ophthalmology, 261(5), 1299-1309. [More Information]
- Zhang, T., Rao, Q., Dai, M., Wu, Z., Zhao, Q., Li, F. (2023). Tripterygium wilfordii protects against an animal model of autoimmune hepatitis. Journal of Ethnopharmacology, 309. [More Information]
- Zhang, T., Deng, R., Wang, Y., Wu, C., Zhang, K., Wang, C., Gong, N., Ledesma-Amaro, R., Teng, X., Yang, C., et al (2022). A paper-based assay for the colorimetric detection of SARS-CoV-2 variants at single-nucleotide resolution. Nature Biomedical Engineering, 6(8), 957-967. [More Information]
- Wu, D., Li, J., Shen, R., Li, J., Yu, Y., Li, L., Deng, S., Liu, T., Zhang, T., Xu, Y., et al (2022). Autophagy Induced by Micheliolide Alleviates Acute Irradiation-Induced Intestinal Injury via Inhibition of the NLRP3 Inflammasome. Frontiers in Pharmacology, 12. [More Information]
- Song, W., Jia, P., Zhang, T., Dou, K., Liu, L., Ren, Y., Liu, F., Xue, J., Hasanin, M., Qi, H., et al (2022). Cell membrane-camouflaged inorganic nanoparticles for cancer therapy. Journal of Nanobiotechnology, 20(1). [More Information]
- Zhang, T., Wu, D., Luo, P., Liu, T., Han, R., Deng, S., He, M., Zhao, Y., Xu, Y. (2022). CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition. Cell Death and Disease, 13(2). [More Information]
- Rao, Q., Zhang, T., Dai, M., Li, B., Pu, Q., Zhao, M., Cheng, Y., Yan, D., Zhao, Q., Wu, Z., et al (2022). Comparative Metabolomic Profiling of the Metabolic Differences of Δ9-Tetrahydrocannabinol and Cannabidiol. Molecules, 27(21). [More Information]
- Wu, Y., Liu, J., Li, H., Zhang, T., Dong, Y., Deng, S., Lv, Y., He, Q., Deng, R. (2022). CRISPR-Cas system meets DNA barcoding: Development of a universal nucleic acid test for food authentication. Sensors and Actuators B: Chemical, 353. [More Information]
- Mu, K., Ren, X., Yang, H., Zhang, T., Yan, W., Yuan, F., Wu, J., Kang, Z., Han, D., Deng, R., et al (2022). CRISPR-Cas12a-Based Diagnostics of Wheat Fungal Diseases. Journal of Agricultural and Food Chemistry, 70(23), 7240-7247. [More Information]
- Wang, Y., Xue, T., Wang, M., Ledesma-Amaro, R., Lu, Y., Hu, X., Zhang, T., Yang, M., Li, Y., Xiang, J., et al (2022). CRISPR-Cas13a cascade-based viral RNA assay for detecting SARS-CoV-2 and its mutations in clinical samples. Sensors and Actuators B: Chemical, 362. [More Information]
- Li, Q., Zhao, B., Li, W., He, Y., Tang, X., Zhang, T., Zhong, Z., Pan, Q., Zhang, Y. (2022). Effects of repeated drug administration on behaviors in normal mice and fluoxetine efficacy in chronic unpredictable mild stress mice. Biochemical and Biophysical Research Communications, 615, 36-42. [More Information]
- He, Y., Zhang, Y., Li, W., Li, Q., Zhao, B., Tang, X., Chen, D., Zhang, T., Zhang, T., Zhong, Z. (2022). Evaluating blood-brain barrier disruption and infarction volume concurrently in rats subjected to ischemic stroke using an optical imaging system. Journal of Neuroscience Methods, 378. [More Information]
- Gao, H., Feng, M., Li, F., Zhang, K., Zhang, T., Zhang, Z., Yang, C., Deng, R., Zhang, J., Jiang, P. (2022). G-Quadruplex DNAzyme-Substrated CRISPR/Cas12 Assay for Label-Free Detection of Single-Celled Parasitic Infection. ACS Sensors, 7(10), 2968-2977. [More Information]
- Qin, W., Zhang, T., Ge, M., Zhou, H., Xu, Y., Mu, R., Huang, C., Liu, D., Huang, B., Wang, Q., et al (2022). Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance. Journal of Endocrinology, 254(3), 137-151. [More Information]
- Sun, X., Zhang, T., Li, M., Yin, L., Xue, J. (2022). Immunosuppressive B cells expressing PD-1/PD-L1 in solid tumors: A mini review. QJM, 115(8), 507-512. [More Information]
- Wu, D., He, M., Zhao, Y., Deng, S., Liu, T., Zhang, T., Zhang, F., Wang, Y., Xu, Y. (2022). Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia. Cell Communication and Signaling, 20(1). [More Information]
- Chen, Y., Coorey, N., Zhang, M., Zeng, S., Madigan, M., Zhang, X., Gillies, M., Zhu, L., Zhang, T. (2022). Metabolism Dysregulation in Retinal Diseases and Related Therapies. Antioxidants, 11(5), 942. [More Information]
- Dai, M., Peng, W., Zhang, T., Zhao, Q., Ma, X., Cheng, Y., Wang, C., Li, F. (2022). Metabolomics reveals the role of PPARα in Tripterygium Wilfordii-induced liver injury. Journal of Ethnopharmacology, 289. [More Information]
- Liu, T., Wu, D., Zhang, F., Zhang, T., He, M., Zhao, Y., Li, J., Li, L., Xu, Y. (2022). miR-142a-3p Enhances FlaA N/C Protection Against Radiation-Mediated Intestinal Injury by Modulating the IRAK1/NF-κB Signaling Pathway. International Journal of Radiation Oncology Biology Physics, 112(5), 1256-1268. [More Information]
- Li, L., Deng, S., Liu, M., Yang, M., Li, J., Liu, T., Zhang, T., Zhao, Y., He, M., Wu, D., et al (2022). Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway. Frontiers in Pharmacology, 13. [More Information]
- Li, L., Wu, D., Deng, S., Li, J., Zhang, F., Zou, Y., Zhang, T., Xu, Y. (2022). NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis. Cell Death Discovery, 8(1). [More Information]
- Wu, X., Tao, M., Zhu, L., Zhang, T., Zhang, M. (2022). Pathogenesis and current therapies for non-infectious uveitis. Clinical and Experimental Medicine. [More Information]
- Pan, Z., Zhao, B., Tang, X., Li, Q., Zhang, T., Zhang, Y., Zhong, Z. (2022). Ruptured brain aneurysm-induced subarachnoid hemorrhage with concurrent myocardial infarction in a rhesus monkey (Macaca mulatta). Journal of Medical Primatology, 51(3), 187-190. [More Information]
- Wu, Y., Zeng, Z., Zhang, T., Liu, C., Xu, J., Deng, R., Wang, Q., Lin, F. (2022). Synergetic dual-toehold mediated controllable transcription amplification for detecting lung cancer-related circulating miRNAs in blood. Sensors and Actuators B: Chemical, 354. [More Information]
- Huang, J., Zhuang, C., Chen, J., Chen, X., Li, X., Zhang, T., Wang, B., Feng, Q., Zheng, X., Gong, M., et al (2022). Targeted Drug/Gene/Photodynamic Therapy via a Stimuli-Responsive Dendritic-Polymer-Based Nanococktail for Treatment of EGFR-TKI-Resistant Non-Small-Cell Lung Cancer. Advanced Materials, 34(27). [More Information]
- Zhang, T., Bai, X., Chi, H., Liu, T., Li, S., Wei, C., Shi, W. (2022). The mounted alloimmunity of the iris-ciliary body devotes a hotbed of immune cells for corneal transplantation rejection. Experimental Eye Research, 222. [More Information]
- Dong, Y., Wang, S., Cong, L., Zhang, T., Cheng, J., Yang, N., Qu, X., Li, D., Zhou, X., Wang, H., et al (2022). TNF-α inhibitor tanfanercept (HBM9036) improves signs and symptoms of dry eye in a phase 2 trial in the controlled adverse environment in China. International Ophthalmology, 42(8), 2459-2472. [More Information]
- Chen, Y., Zhang, T., Zeng, S., Xu, R., Jin, K., Coorey, N., Wang, Y., Wang, K., Lee, S., Yam, M., Zhu, M., Chang, A., Fan, X., Gillies, M., Zhu, L., et al (2022). Transketolase in human Müller cells is critical to resist light stress through the pentose phosphate and NRF2 pathways. Redox Biology, 54, 102379. [More Information]
- Chi, H., Hao, W., Qi, X., Zhang, T., Dong, Y., Gao, H., Wei, C., Shi, W. (2021). A proteomic approach towards understanding the pathogenesis of Mooren's ulcer. Experimental Eye Research, 205. [More Information]
- He, M., Wu, D., Zhao, Y., Yu, Y., Deng, S., Liu, T., Zhang, T., Li, J., Wang, F., Xu, Y. (2021). AZD8055 ameliorates experimental autoimmune encephalomyelitis via the mTOR/ROS/NLRP3 pathway. Biochemical and Biophysical Research Communications, 573, 27-34. [More Information]
- Li, H., Chen, M., Zhou, Q., Pan, X., Cheng, J., Cong, L., Zhang, T., Dong, Y., Xie, L. (2021). Biomechanical effects of deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: A finite element analysis. Translational Vision Science and Technology, 10(9). [More Information]
- Zhang, T., Tang, J., Fei, X., Li, Y., Song, Y., Qian, Z., Peng, Q. (2021). Can nanoparticles and nano‒protein interactions bring a bright future for insulin delivery? Acta Pharmaceutica Sinica B, 11(3), 651-667. [More Information]
- Li, Z., Wu, X., Zhao, Y., Xiao, Y., Zhao, Y., Zhang, T., Li, H., Sha, F., Wang, Y., Deng, L., et al (2021). Clinical benefit of neoadjuvant anti-PD-1/PD-L1 utilization among different tumors. MedComm, 2(1), 60-68. [More Information]
- Jia, Y., Qi, X., Zhang, T., Liu, M., Shi, W., Gao, H. (2021). Clinical outcomes of double continuous suture in femtosecond laser-assisted lamellar keratoplasty for keratoconus. Lasers in Medical Science, 36(5), 951-956. [More Information]
- Yang, H., Chen, J., Yang, S., Zhang, T., Xia, X., Zhang, K., Deng, S., He, G., Gao, H., He, Q., et al (2021). CRISPR/Cas14a-Based Isothermal Amplification for Profiling Plant MicroRNAs. Analytical Chemistry, 93(37), 12602-12608. [More Information]
- Wang, Y., Zhang, Y., Chen, J., Wang, M., Zhang, T., Luo, W., Li, Y., Wu, Y., Zeng, B., Zhang, K., et al (2021). Detection of SARS-CoV-2 and Its Mutated Variants via CRISPR-Cas13-Based Transcription Amplification. Analytical Chemistry, 93(7), 3393-3402. [More Information]
- Zhang, T., Li, H., Xia, X., Liu, J., Lu, Y., Khan, M., Deng, S., Busquets, R., He, G., He, Q., et al (2021). Direct Detection of Foodborne Pathogens via a Proximal DNA Probe-Based CRISPR-Cas12 Assay. Journal of Agricultural and Food Chemistry, 69(43), 12828-12836. [More Information]
- Zhou, Z., Yan, D., Wang, Y., Zhang, T., Xiao, X., Dai, M., Zhang, S., Liu, H., Li, F. (2021). Discovery of quality markers in Rubus Chingii Hu using UPLC-ESI-QTOF-MS. Journal of Pharmaceutical and Biomedical Analysis, 203. [More Information]
- Zeng, H., Zhang, T., Deng, R., Ren, Y., Jia, L. (2021). Establishment of A Rapid RNA Detection Method for Listeria monocytogenes Based on CRISPR-Cas13. Xiandai Shipin Keji, 37(5). [More Information]
- Huang, H., Liu, Q., Zhang, T., Zhang, J., Zhou, J., Jing, X., Tang, Q., Huang, C., Zhang, Z., Zhao, Y., et al (2021). Farnesylthiosalicylic Acid-Loaded Albumin Nanoparticle Alleviates Renal Fibrosis by Inhibiting Ras/Raf1/p38 Signaling Pathway. International Journal of Nanomedicine, 16, 6441-6453. [More Information]
- Xia, X., Ma, B., Zhang, T., Lu, Y., Khan, M., Hu, Y., Lei, C., Deng, S., He, Q., He, G., et al (2021). G-Quadruplex-Probing CRISPR-Cas12 Assay for Label-Free Analysis of Foodborne Pathogens and Their ColonizationIn Vivo. ACS Sensors, 6(9), 3295-3302. [More Information]
- Xiao, Q., Xue, T., Shuai, W., Wu, C., Zhang, Z., Zhang, T., Zeng, S., Sun, B., Wang, Y. (2021). High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design. Biochemical and Biophysical Research Communications, 534, 330-336. [More Information]
- Luo, W., Wang, Z., Zhang, T., Yang, L., Xian, J., Li, Y., Li, W. (2021). Immunotherapy in non-small cell lung cancer: rationale, recent advances and future perspectives. Precision Clinical Medicine, 4(4), 258-270. [More Information]
- Mei, L., Zhang, D., Shao, H., Hao, Y., Zhang, T., Zheng, W., Ji, Y., Ling, P., Lu, Y., Zhou, Q. (2021). Injectable and Self-Healing Probiotics-Loaded Hydrogel for Promoting Superbacteria-Infected Wound Healing. ACS Applied Materials and Interfaces. [More Information]
- Chen, Y., Zhang, T., Zeng, S., Yam, M., Gillies, M., Zhu, L. (2021). Isolation, culture, and identification of primary Müller cells from human retina. Bio-protocol, 11(19), e4179. [More Information]
- Zhang, T., Zhou, W., Lin, X., Khan, M., Deng, S., Zhou, M., He, G., Wu, C., Deng, R., He, Q. (2021). Light-up RNA aptamer signaling-CRISPR-Cas13a-based mix-and-read assays for profiling viable pathogenic bacteria. Biosensors and Bioelectronics, 176. [More Information]
- Deng, S., Wu, D., Li, L., Liu, T., Zhang, T., Li, J., Yu, Y., He, M., Zhao, Y., Han, R., et al (2021). miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549. Biochemical and Biophysical Research Communications, 549, 54-60. [More Information]
- Zhao, Y., Chen, R., Zhang, T., Chen, C., Muhelisa, M., Huang, J., Xu, Y., Ma, X. (2021). MRI-Based Machine Learning in Differentiation Between Benign and Malignant Breast Lesions. Frontiers in Oncology, 11. [More Information]
- Chen, X., Shen, C., Wei, Z., Zhang, R., Wang, Y., Jiang, L., Chen, K., Qiu, S., Zhang, Y., Zhang, T., et al (2021). Patient-derived non-small cell lung cancer xenograft mirrors complex tumor heterogeneity. Cancer Biology & Medicine, 18(1), 184-198. [More Information]
- Zhang, T., Sun, J., Li, J., Zhao, Y., Zhang, T., Yang, R., Ma, X. (2021). Safety and efficacy profile of mogamulizumab (Poteligeo) in the treatment of cancers: an update evidence from 14 studies. BMC Cancer, 21(1). [More Information]
- Zhao, Y., Wu, D., He, M., Zhang, F., Zhang, T., Liu, T., Li, J., Li, L., Xu, Y. (2021). Samotolisib Attenuates Acute Liver Injury Through Inhibiting Caspase-11-Mediated Pyroptosis Via Regulating E3 Ubiquitin Ligase Nedd4. Frontiers in Pharmacology, 12. [More Information]
- Zhou, J., Li, R., Zhang, J., Liu, Q., Wu, T., Tang, Q., Huang, C., Zhang, Z., Huang, Y., Huang, H., et al (2021). Targeting Interstitial Myofibroblast-Expressed Integrin αvβ3 Alleviates Renal Fibrosis. Molecular Pharmaceutics, 18(3), 1373-1385. [More Information]
- Wu, D., Deng, S., Li, L., Liu, T., Zhang, T., Li, J., Yu, Y., Xu, Y. (2021). TGF-β1-mediated exosomal lnc-MMP2-2 increases blood–brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis. Cell Death and Disease, 12(8). [More Information]
- Cheng, Z., Li, Y., Zhu, X., Wang, K., Ali, Y., Shu, W., Zhang, T., Zhu, L., Murray, M., Zhou, F. (2021). The Potential Application of Pentacyclic Triterpenoids in the Prevention and Treatment of Retinal Diseases. Planta Medica: natural products and medicinal plant research, 87(7), 511-527. [More Information]
- Li, W., Tan, L., Zhang, Z., Xia, Q., Lei, D., Li, Y., Zhang, T., Zeng, S., Sima, X., Wang, Y. (2021). The X-ray structure of tubulysin analogue TGL in complex with tubulin and three possible routes for the development of next-generation tubulysin analogues. Biochemical and Biophysical Research Communications, 565, 29-35. [More Information]
- Zheng, X., Zheng, X., Zheng, X., Yang, X., Yang, X., Wan, J., Wan, J., Zhang, T., Zhang, T., Yang, Z., et al (2020). A novel super thermal insulation material: Bamboo-like polymer nanotubes. Nanotechnology, 31(34). [More Information]
- Wu, D., Liu, T., Deng, S., Han, R., Zhang, T., Li, J., Xu, Y. (2020). Alpha-1 antitrypsin induces epithelial-to-mesenchymal transition, endothelial-to-mesenchymal transition, and drug resistance in lung cancer cells. OncoTargets and Therapy, 13, 3751-3763. [More Information]
- Li, J., Wu, D., Yu, Y., Deng, S., Liu, T., Zhang, T., He, M., Zhao, Y., Xu, Y. (2020). Amifostine ameliorates induction of experimental autoimmune encephalomyelitis: Effect on reactive oxygen species/NLRP3 pathway. International Immunopharmacology, 88. [More Information]
- Yu, Y., Wu, D., Li, J., Deng, S., Liu, T., Zhang, T., He, M., Zhao, Y., Xu, Y. (2020). Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling. Frontiers in Immunology, 11. [More Information]
- Zhao, Q., Tang, P., Zhang, T., Huang, J., Xiao, X., Zhu, W., Gonzalez, F., Li, F. (2020). Celastrol ameliorates acute liver injury through modulation of PPARα. Biochemical Pharmacology, 178. [More Information]
- Cheng, J., Dong, Y., Zhai, H., Cong, L., Zhang, T., Wang, S., Xie, L. (2020). Clinical observation of ocular injury caused by chestnut burr. Zhonghua Yanke Zazhi, 56(5), 370-375. [More Information]
- Zhang, T., Li, Y., Song, Y., Chen, X., Li, J., Peng, Q., He, J., Fei, X. (2020). Curcumin-and cyclopamine-loaded liposomes to enhance therapeutic efficacy against hepatic fibrosis. Drug Design, Development and Therapy, 14, 5667-5678. [More Information]
- Xiao, X., Zhang, T., Huang, J., Zhao, Q., Li, F. (2020). Effect of CYP3A4 on liver injury induced by triptolide. Biomedical Chromatography, 34(8). [More Information]
- Dong, Y., Zhang, T., Lin, X., Feng, J., Luo, F., Gao, H., Wu, Y., Deng, R., He, Q. (2020). Graphene/aptamer probes for small molecule detection: from in vitro test to in situ imaging. Microchimica Acta, 187(3). [More Information]
- Huang, J., Zhao, Q., Dai, M., Xiao, X., Zhang, T., Zhu, W., Li, F. (2020). Gut microbiota protects from triptolide-induced hepatotoxicity: Key role of propionate and its downstream signalling events. Pharmacological Research, 155. [More Information]
- Liu, H., Zhang, T., Jiang, P., Zhu, W., Yu, S., Liu, Y., Li, B., Li, F. (2020). Hypolipidemic constituents from the aerial portion of Sibiraea angustata. Bioorganic & Medicinal Chemistry Letters, 30(11). [More Information]
- Zhang, T., Jia, Y., Li, S., Shi, W. (2020). Individualized corneal patching for treatment of corneal trauma combined with tissue defects. Journal of Ophthalmology, 2020. [More Information]
- Li, J., Wu, D., Han, R., Deng, Y., Liu, T., Zhang, T., Xu, Y. (2020). Low-dose radiation promotes invasion and migration of a549 cells by activating the cxcl1/ nf-κb signaling pathway. OncoTargets and Therapy, 13, 3619-3629. [More Information]
- Li, B., Zhang, T., Liu, W., Wang, Y., Xu, R., Zeng, S., Zhang, R., Zhu, S., Gillies, M., Zhu, L., et al (2020). Metabolic Features of Mouse and Human Retinas: Rods versus Cones, Macula versus Periphery, Retina versus RPE. iScience, 23(11), 101672. [More Information]
- Zhou, Z., Wang, Y., Yan, D., Fang, J., Xiao, X., Zhang, T., Cheng, Y., Xu, K., Li, F. (2020). Metabolic profiling of tyrosine kinase inhibitor nintedanib using metabolomics. Journal of Pharmaceutical and Biomedical Analysis, 180. [More Information]
- Wu, D., Deng, S., Zhou, J., Han, R., Liu, T., Zhang, T., Li, J., Chen, J., Xu, Y. (2020). PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer. International Journal of Cancer, 146(9), 2563-2575. [More Information]
- Zhang, T., Wu, D., Deng, S., Han, R., Liu, T., Li, J., Xu, Y. (2020). RNAseq profiling of circRNA expression in radiation-treated A549 cells and bioinformatics analysis of radiation-related circRNA-miRNA networks. Oncology Letters, 20(2), 1557-1566. [More Information]
- Yu, C., Chen, G., Xia, M., Xie, Y., Chi, Y., He, Z., Zhang, C., Zhang, T., Chen, Q., Peng, Q. (2020). Understanding the sheet size-antibacterial activity relationship of graphene oxide and the nano-bio interaction-based physical mechanisms. Colloids And Surfaces B: Biointerfaces, 191. [More Information]
- Feng, Z., Yu, Q., Zhang, T., Tie, W., Li, J., Zhou, X. (2020). Updates on mechanistic insights and targeting of tumour metastasis. Journal of Cellular and Molecular Medicine, 24(3), 2076-2086. [More Information]
- Xia, X., Zhang, T., Deng, S., Chen, J., Wu, S., He, C., Zhang, K., Deng, R., He, Q. (2020). Visualization of Mycotoxins in Living Cells Using Conformation-Resolved Aptamer Nanoprobes. ACS Sustainable Chemistry and Engineering, 8(26), 9920-9925. [More Information]
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2018
- Shen, W., Lee, S., Yam, M., Zhu, L., Zhang, T., Pye, V., Mathai, A., Shibagaki, K., Zhang, J., Matsugi, T., Gillies, M. (2018). A Combination Therapy Targeting Endoglin and VEGF-A Prevents Subretinal Fibro-Neovascularization Caused by Induced Muller Cell Disruption. Investigative Ophthalmology and Visual Science, 59(15), 6075-6088. [More Information]
- Zhu, G., Lu, B., Zhang, T., Zhang, T., Zhang, C., Li, Y., Peng, Q. (2018). Antibiofilm effect of drug-free and cationic poly(D,L-lactide-co-glycolide) nanoparticles via nano-bacteria interactions. Nanomedicine, 13(10), 1093-1106. [More Information]
- Zhu, L., Shen, W., Zhang, T., Wang, Y., Bahrami, B., Zhou, F., Gillies, M. (2018). Characterization of canonical Wnt signalling changes after induced disruption of Muller cell in murine retina. Experimental Eye Research, 175, 173-180. [More Information]
- Zhang, T., Li, Z., Liu, T., Li, S., Gao, H., Wei, C., Shi, W. (2018). Cyclosporine a drug-delivery system for high-risk penetrating keratoplasty: Stabilizing the intraocular immune microenvironment. PloS One, 13(5). [More Information]
- Zhang, T., Gillies, M., Madigan, M., Shen, W., Du, J., Grunert, U., Zhou, F., Yam, M., Zhu, L. (2018). Disruption of De Novo Serine Synthesis in Müller Cells Induced Mitochondrial Dysfunction and Aggravated Oxidative Damage. Molecular Neurobiology, 55(8), 7025-7037. [More Information]
- Huang, L., Dai, F., Tang, L., Bao, X., Liu, Z., Huang, C., Zhang, T., Yao, W. (2018). Distinct Roles for ROCK1 and ROCK2 in the Regulation of Oxldl-Mediated Endothelial Dysfunction. Cellular Physiology and Biochemistry, 49(2), 565-577. [More Information]
- Wei, X., Zhang, T., Yao, Y., Zeng, S., Li, M., Xiang, H., Zhao, C., Cao, G., Li, M., Wan, R., et al (2018). Efficacy of Lenvatinib, a multitargeted tyrosine kinase inhibitor, on laser-induced CNV mouse model of neovascular AMD. Experimental Eye Research, 168, 2-11. [More Information]
- Liu, J., Dong, J., Zhang, T., Peng, Q. (2018). Graphene-based nanomaterials and their potentials in advanced drug delivery and cancer therapy. Journal of Controlled Release, 286, 64-73. [More Information]
- Zhang, T., Bahrami, B., Zhu, L. (2018). Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retina. In Alexzander A. A. Asea, Punit Kaur (Eds.), HSP70 in human diseases and disorders, (pp. 273-287). Cham: Springer. [More Information]
- Zhang, T., Wu, D., Deng, S., Han, R., Liu, T., Li, J., Xu, Y. (2018). Integrated Analysis Reveals That Long Non-Coding RNA TUBA4B Can Be Used as a Prognostic Biomarker in Various Cancers. Cellular Physiology and Biochemistry, 49(2), 530-544. [More Information]
- Wang, L., Xiao, F., Kong, L., Wang, D., Li, H., Wei, Y., Tan, C., Zhao, H., Zhang, T., Cao, G., et al (2018). Intermedin Enlarges the Vascular Lumen by Inducing the Quiescent Endothelial Cell Proliferation. Arteriosclerosis, Thrombosis, and Vascular Biology, 38(2), 398-413. [More Information]
- Yao, Y., Liao, W., Yu, R., Du, Y., Zhang, T., Peng, Q. (2018). Potentials of combining nanomaterials and stem cell therapy in myocardial repair. Nanomedicine, 13(13), 1623-1638. [More Information]
- Wu, D., Han, R., Deng, S., Liu, T., Zhang, T., Xie, H., Xu, Y. (2018). Protective Effects of Flagellin A N/C Against Radiation-Induced NLR Pyrin Domain Containing 3 Inflammasome-Dependent Pyroptosis in Intestinal Cells. International Journal of Radiation Oncology Biology Physics, 101(1), 107-117. [More Information]
- Wu, D., Deng, S., Liu, T., Han, R., Zhang, T., Xu, Y. (2018). TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression. Cancer Medicine, 7(10), 5118-5129. [More Information]
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2017
- Zhang, T., Zhang, J., Sun, X., Tian, J., Shi, W., Yuan, G. (2017). Early vitrectomy for dense vitreous hemorrhage in adults with non-traumatic and non-diabetic retinopathy. Journal of international medical research, 45(6), 2065-2071. [More Information]
- Zhang, J., Yuan, G., Dong, M., Zhang, T., Hua, G., Zhou, Q., Shi, W. (2017). Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-to-mesenchymal transition. Histochemistry and Cell Biology, 147(3), 367-375. [More Information]
- Zhang, T., Luo, J., Fu, Y., Li, H., Ding, R., Gong, T., Zhang, Z. (2017). Novel oral administrated paclitaxel micelles with enhanced bioavailability and antitumor efficacy for resistant breast cancer. Colloids And Surfaces B: Biointerfaces, 150, 89-97. [More Information]
- Li, Z., Ottmann, A., Zhang, T., Sun, Q., Meyer, H., Vaynzof, Y., Xiang, J., Klingeler, R. (2017). Preparation of hierarchical C@MoS
2 @C sandwiched hollow spheres for lithium ion batteries. Journal of Materials Chemistry A, 5(8), 3987-3994. [More Information] - Zhang, T., Sai, H., Guan, Y., Fu, R., Yang, H., Jia, H., Yue, X., Xiang, J. (2017). Surface modification of metal mesh with SiO
2 films for enhanced corrosion protection. International Journal of Applied Ceramic Technology, 14(5), 899-907. [More Information] - Zhang, Y., Fan, F., Zeng, G., Zhou, L., Zhang, Y., Zhang, J., Jiao, H., Zhang, T., Su, D., Yang, C., et al (2017). Temporal analysis of blood–brain barrier disruption and cerebrospinal fluid matrix metalloproteinases in rhesus monkeys subjected to transient ischemic stroke. Journal of Cerebral Blood Flow and Metabolism, 37(8), 2963-2974. [More Information]
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2016
- Luo, J., Zhang, T., Zhang, Q., Cao, X., Zeng, X., Fu, Y., Zhang, Z., Gong, T. (2016). A novel injectable phospholipid gel co-loaded with doxorubicin and bromotetrandrine for resistant breast cancer treatment by intratumoral injection. Colloids And Surfaces B: Biointerfaces, 140, 538-547. [More Information]
- Zhang, T., Wang, Y., Jia, Y., Liu, D., Li, S., Shi, W., Gao, H. (2016). Active Pedicle Epithelial Flap Transposition Combined with Amniotic Membrane Transplantation for Treatment of Nonhealing Corneal Ulcers. Journal of Ophthalmology, 2016. [More Information]
- Li, Y., Liu, Q., Li, W., Zhang, T., Li, H., Li, R., Chen, L., Pu, S., Kuang, J., Su, Z., et al (2016). Design and Validation of PEG-Derivatized Vitamin E Copolymer for Drug Delivery into Breast Cancer. Bioconjugate Chemistry, 27(8), 1889-1899. [More Information]
- Li, Y., Li, R., Liu, Q., Li, W., Zhang, T., Zou, M., Li, H., Wu, T., Cheng, S., Su, Z., et al (2016). One-step self-assembling nanomicelles for pirarubicin delivery to overcome multidrug resistance in breast cancer. Molecular Pharmaceutics, 13(11), 3934-3944. [More Information]
- Ma, L., Zhang, T., Li, Y., Wang, X., Meng, Z. (2016). Preparation and characterization of the PBLA-POLO-PBLA nanoparticles. Sichuan Daxue Xuebao (Gongcheng Kexue Ban), 48(3), 202-208. [More Information]
- Li, Z., Chen, Z., Zhang, T., Wei, C., Shi, W. (2016). TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response. Aging, 8(10), 2337-2354. [More Information]
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2015
- Zhang, T., Peng, Q., San, F., Luo, J., Wang, M., Wu, W., Gong, T., Zhang, Z. (2015). A high-efficiency, low-toxicity, phospholipids-based phase separation gel for long-term delivery of peptides. Biomaterials, 45, 1-9. [More Information]
- Zhang, J., Chu, S., Sun, X., Zhang, T., Shi, W. (2015). Bevacizumab modulates retinal pigment epithelial-to- mesenchymal transition via regulating Notch signaling. International Journal of Ophthalmology, 8(2), 245-249. [More Information]
- Peng, Q., Wei, X., Yang, Q., Zhang, S., Zhang, T., Shao, X., Cai, X., Zhang, Z., Lin, Y. (2015). Enhanced biostability of nanoparticle-based drug delivery systems by albumin corona. Nanomedicine, 10(2), 205-214. [More Information]
- Zhang, T., Xie, X., Zeng, Z., Meng, D., Lu, F. (2015). Molecular genetic analysis and clinical phenotype of a pedigree with familial dominant drusen. Zhonghua Yixue Yichuanxue Zazhi, 32(3), 358-362. [More Information]
- Ma, L., Ma, P., Zhang, T., Zeng, X. (2015). Preparation and evaluation of glycyrrhetinic acid-modified poly(β-benzyl-L-asparate) nanoparticles. Sichuan Daxue Xuebao (Gongcheng Kexue Ban), 47(3), 187-192. [More Information]
- Li, H., Fu, Y., Zhang, T., Li, Y., Hong, X., Jiang, J., Gong, T., Zhang, Z., Sun, X. (2015). Rational Design of Polymeric Hybrid Micelles with Highly Tunable Properties to Co-Deliver MicroRNA-34a and Vismodegib for Melanoma Therapy. Advanced Functional Materials, 25(48), 7457-7469. [More Information]
- Sai, H., Fu, R., Xing, L., Xiang, J., Li, Z., Li, F., Zhang, T. (2015). Surface modification of bacterial cellulose aerogels' web-like skeleton for oil/water separation. ACS Applied Materials and Interfaces, 7(13), 7373-7381. [More Information]
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2014
- Sai, H., Xing, L., Xiang, J., Cui, L., Jiao, J., Zhao, C., Li, Z., Li, F., Zhang, T. (2014). Flexible aerogels with interpenetrating network structure of bacterial cellulose-silica composite from sodium silicate precursor via freeze drying process. RSC Advances, 4(57), 30453-30461. [More Information]
- Zhang, T., Xie, X., Cao, G., Jiang, H., Wu, S., Su, Z., Zhang, K., Lu, F. (2014). Malattia leventinese/doyne honeycomb retinal dystrophy in a Chinese family with mutation of the EFEMP1 gene. Retina, 34(12), 2462-2471. [More Information]
- Peng, Q., Wei, X., Shao, X., Zhang, T., Zhang, S., Fu, N., Cai, X., Zhang, Z., Lin, Y. (2014). Nanocomplex based on biocompatible phospholipids and albumin for long-circulation applications. ACS Applied Materials and Interfaces, 6(16), 13730-13737. [More Information]
2013
- Zhang, T., Zheng, Y., Peng, Q., Cao, X., Gong, T., Zhang, Z. (2013). A novel submicron emulsion system loaded with vincristine-oleic acid ion-pair complex with improved anticancer effect: In vitro and in vivo studies. International Journal of Nanomedicine, 8, 1185-1196. [More Information]
- Jiang, H., Huang, X., Su, Z., Rao, L., Wu, S., Zhang, T., Li, K., Quan, Q., Zhang, K. (2013). Genetic analysis of the forkhead transcriptional factor 2 gene in three Chinese families with blepharophimosis syndrome. Molecular Vision, 19, 418-423.
- Peng, Q., Sun, X., Gong, T., Wu, C., Zhang, T., Tan, J., Zhang, Z. (2013). Injectable and biodegradable thermosensitive hydrogels loaded with PHBHHx nanoparticles for the sustained and controlled release of insulin. Acta Biomaterialia, 9(2), 5063-5069. [More Information]
- Peng, Q., Zhang, S., Yang, Q., Zhang, T., Wei, X., Jiang, L., Zhang, C., Chen, Q., Zhang, Z., Lin, Y. (2013). Preformed albumin corona, a protective coating for nanoparticles based drug delivery system. Biomaterials, 34(33), 8521-8530. [More Information]
- Peng, Q., Yang, Y., Zhang, T., Wu, C., Yang, Q., Sun, X., Gong, T., Zhang, L., Zhang, Z. (2013). The implantable and biodegradable PHBHHx 3D scaffolds loaded with protein-phospholipid complex for sustained delivery of proteins. Pharmaceutical Research, 30(4), 1077-1085. [More Information]
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Selected Grants
2022
- Targeting Nrf2-MAFF pathway in Mller cells to treat macula degeneration, Zhu L, Gilles M, Zhang T, Ophthalmic Research Institute of Australia (ORIA)/ORIA Grant
2021
- Activating endogenous phosphoglycerate dehydrogenase (PHGDH) to treat age-related macular degeneration with the help of a Muller cell-specific lipid nanocarrier, Zhang T, Gillies M, Chrzanowski W, Macular Disease Foundation Australia/Research Grant
2020
- Targeting the pentose phosphate pathway in Mller cells to treat photoreceptor degeneration, Zhang T, Gillies M, Ophthalmic Research Institute of Australia (ORIA)/Research Grants
2019
- Targeting a novel pathogenic glia-neuronal pathway in retinal diseases, Gillies M, Zhu L, Fan X, Zhang T, Fernando N, Zhou F, National Health and Medical Research Council (NHMRC)/Ideas Grant
- Novel approaches to advance the research on human macular degeneration, Zhu L, Fan X, Gillies M, Zhou F, Zhang T, Cheng Z, Office of Global Engagement/Partnership Collaboration Awards
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