Professor Wendy Cooper
People_

Professor Wendy Cooper

Clinical Professor
Sydney Medical School / Central Clinical School
Phone
02 95157458
Professor Wendy Cooper

Professor Wendy Cooper is a Senior Staff Specialist in Tissue Pathology and Diagnostic Oncology at Royal Prince Alfred Hospital; Anatomical Pathology Clinical Stream Lead for NSW Health Pathology; a Clinical Professor at the University of Sydney and a Conjoint Professor at the University of Western Sydney. Wendy graduated from Medicine at the University of Sydney with First Class Honours in 1998. She also received a Bachelor of Science (Med) with First Class Honours in 1996. She obtained her Fellowship from the Royal Australasian College of Pathologists in 2004 and in 2008 completed a PhD from the University of Sydney titled “Molecular markers of prognosis in early stage non-small cell lung cancer” for which she received the prestigious Peter Bancroft Prize.

Her primary interest is in pulmonary pathology, haematopathology and molecular pathology. Wendy is the Chair of the Pathology Committee of the International Association for the Study of Lung Cancer and the Thoracic series champion for the International Collaboration on Cancer Reporting. She was one of the editors and authors of the 5th edition of the WHO classification of thoracic tumours.

Her major research interest is in prognostic and predictive biomarkers in lung cancer. She has published extensive work in this area and enjoys being able to rapidly translate cutting edge research findings into clinical practice for the benefit of patients.

Lung cancer

Lymphoma

Lung pathology

Haematopathology

Cancer
Project titleResearch student
The Role of Co Mutations in clinical and pre clinical outcomes in KRAS mutant non small cell lung cancer.Alex DAVIS

Publications

Journals

  • Cooper, W., Yatabe, Y., Nicholson, A., Webster, F., Butnor, K., Calabrese, F., Chou, T., Hwang, D., Kern, I., Popat, S., et al (2024). Data set for the reporting of lung cancer: recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology. [More Information]
  • Barnes, H., Beckert, L., Milne, D., De Losa, R., Cooper, W., Bell, P., Balakrishnan, P., Troy, L., Corte, T., Keir, G., Limaye, S., et al (2024). Diagnosis and management of hypersensitivity pneumonitis in adults: A position statement from the Thoracic Society of Australia and New Zealand. Respirology. [More Information]
  • Klebe, S., Judge, M., Brcic, L., Dacic, S., Galateau-Salle, F., Nicholson, A., Roggli, V., Nowak, A., Cooper, W. (2024). Mesothelioma in the pleura, pericardium and peritoneum: Recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology, 84(4), 633-645. [More Information]

2024

  • Cooper, W., Yatabe, Y., Nicholson, A., Webster, F., Butnor, K., Calabrese, F., Chou, T., Hwang, D., Kern, I., Popat, S., et al (2024). Data set for the reporting of lung cancer: recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology. [More Information]
  • Barnes, H., Beckert, L., Milne, D., De Losa, R., Cooper, W., Bell, P., Balakrishnan, P., Troy, L., Corte, T., Keir, G., Limaye, S., et al (2024). Diagnosis and management of hypersensitivity pneumonitis in adults: A position statement from the Thoracic Society of Australia and New Zealand. Respirology. [More Information]
  • Klebe, S., Judge, M., Brcic, L., Dacic, S., Galateau-Salle, F., Nicholson, A., Roggli, V., Nowak, A., Cooper, W. (2024). Mesothelioma in the pleura, pericardium and peritoneum: Recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology, 84(4), 633-645. [More Information]

2023

  • Fernando, C., Jayasekara, W., Inampudi, C., Kohonen-Corish, M., Cooper, W., Beilharz, T., Josephs, T., Garama, D., Gough, D. (2023). A STAT3 protein complex required for mitochondrial mRNA stability and cancer. Cell Reports, 42(9). [More Information]
  • Roden, A., Szolkowska, M., Cooper, W., Judge, M., den Bakker, M., Fang, W., Jain, D., Marx, A., Moreira, A., Rajan, A., et al (2023). Dataset for reporting of thymic epithelial tumours: recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology, 83(6), 967-980. [More Information]
  • Maleszewski, J., Basso, C., Burke, A., Castonguay, M., Leduc, C., Tavora, F., Sheppard, M., Suri, R., Judge, M., Cooper, W. (2023). Dataset for the reporting of neoplasms of the heart, pericardium, and great vessels: recommendations from the International Collaboration on Cancer Reporting (ICCR). Virchows Archiv, 482(2), 303-309. [More Information]

2022

  • Clynick, B., Corte, T., Jo, H., Stewart, I., Glaspole, I., Grainge, C., Maher, T., Navaratnam, V., Hubbard, R., Hopkins, P., Cooper, W., et al (2022). Biomarker signatures for progressive idiopathic pulmonary fibrosis. European Respiratory Journal, 59(3), 1-12. [More Information]
  • Walsh, S., Mackintosh, J., Calandriello, L., Silva, M., Sverzellati, N., Larici, A., Humphries, S., Lynch, D., Jo, H., Glaspole, I., Cooper, W., et al (2022). Deep Learning-based Outcome Prediction in Progressive Fibrotic Lung Disease Using High-Resolution Computed Tomography. American Journal of Respiratory and Critical Care Medicine, 206(7), 883-891. [More Information]
  • Parker, A., Bowman, E., Zingone, A., Ryan, B., Cooper, W., Kohonen-Corish, M., Harris, C., Cox, T. (2022). Extracellular matrix profiles determine risk and prognosis of the squamous cell carcinoma subtype of non-small cell lung carcinoma. Genome Medicine, 14(1). [More Information]

2021

  • Cooper, W., Mahar, A., Myers, J., Grainge, C., Corte, T., Williamson, J., Vallely, M., Lai, S., Mulyadi, E., Torzillo, P., Lau, E., Troy, L., et al (2021). Cryobiopsy for Identification of Usual Interstitial Pneumonia and Other Interstitial Lung Disease Features: Further Lessons from COLDICE, a Prospective Multi-Center Study. American Journal of Respiratory and Critical Care Medicine, 203(10), 1306-1313. [More Information]
  • Woodford, R., Lu, M., Beydoun, N., Cooper, W., Liu, Q., Lynch, J., Kasherman, L. (2021). Disseminated intravascular coagulation complicating diagnosis of ROS1-mutant non-small cell lung cancer: A case report and literature review. Thoracic Cancer, 12(17), 2400-2403. [More Information]
  • Davis, A., Cooper, W., Boyer, M., Lee, J., Pavlakis, N., Kao, S. (2021). Efficacy of immunotherapy in KRAS-mutant non-small-cell lung cancer with comutations. Immunotherapy, 13(11), 941-952. [More Information]

2020

  • Moreira, A., Ocampo, P., Xia, Y., Zhong, H., Russell, P., Minami, Y., Cooper, W., Yoshida, A., Bubendorf, L., Papotti, M., et al (2020). A Grading System for Invasive Pulmonary Adenocarcinoma: A Proposal From the International Association for the Study of Lung Cancer Pathology Committee. Journal of Thoracic Oncology, 15(10), 1599-1610. [More Information]
  • Hendry, S., Byrne, N., Christie, M., Steinfort, D., Irving, L., Wagner, C., Ellwood, T., Cooper, W., Fox, S. (2020). Adequate tumour cellularity is essential for accurate PD-L1 immunohistochemistry assessment on cytology cell block specimens. Cytopathology, 31(2), 90-95. [More Information]
  • Itchins, M., Lau, B., Hudson, A., Westman, H., Xia, C., Hayes, S., Howell, V., Rodriguez, M., Cooper, W., Wei, G., Buckland, M., Li, B., Gill, A., Clarke, S., Pavlakis, N., et al (2020). ALK-Rearranged Non-Small Cell Lung Cancer in 2020: Real-World Triumphs in an Era of Multigeneration ALK-Inhibitor Sequencing Informed by Drug Resistance Profiling. The Oncologist, 25(8), 641-649. [More Information]

2019

  • Pavlakis, N., Cooper, C., John, T., Kao, S., Klebe, S., Lee, C., Leong, T., Millward, M., O'Byrne, K., Russell, P., Cooper, W., et al (2019). Australian consensus statement for best practice ROS1 testing in advanced non-small cell lung cancer. Pathology, 51(7), 673-680. [More Information]
  • Luk, P., Selinger, C., Cooper, W., Mahar, A., Palme, C., O'Toole, S., Clark, J., Gupta, R. (2019). Clinical Utility of In Situ Hybridization Assays in Head and Neck Neoplasms. Head and Neck Pathology, 13(3), 397-414. [More Information]
  • Troy, L., Grainge, C., Corte, T., Williamson, J., Vallely, M., Cooper, W., Mahar, A., Lai, S., Mulyadi, E., Torzillo, P., Lau, E., et al (2019). Cryobiopsy versus open lung biopsy in the diagnosis of interstitial lung disease (COLDICE): protocol of a multicentre study. BMJ Open Respiratory Research, 6(1), 1-8. [More Information]

2018

  • Ahmadzada, T., Kao, S., Reid, G., Boyer, M., Mahar, A., Cooper, W. (2018). An Update on Predictive Biomarkers for Treatment Selection in Non-Small Cell Lung Cancer. Journal of Clinical Medicine, 7(6), E153. [More Information]
  • Luk, P., Selinger, C., Mahar, A., Cooper, W. (2018). Biomarkers for ALK and ROS1 in Lung Cancer: Immunohistochemistry and Fluorescent In Situ Hybridization. Archives of Pathology & Laboratory Medicine, 142(8), 922-928. [More Information]
  • Cooper, W., Barnet, M., Kao, S., Scolyer, R. (2018). Biomarkers that predict response to immunotherapy-no magic bullet. Cancer Forum, 42(1), 1-10. [More Information]

2017

  • Jo, H., Glaspole, I., Grainge, C., Goh, N., Hopkins, P., Moodley, Y., Reynolds, P., Chapman, S., Walters, E., Cooper, W., Corte, T., et al (2017). Baseline characteristics of idiopathic pulmonary fibrosis: analysis from the Australian Idiopathic Pulmonary Fibrosis Registry. European Respiratory Journal, 49(2), 1-11. [More Information]
  • Glaspole, I., Watson, A., Allan, H., Chapman, S., Cooper, W., Corte, T., Ellis, S., Grainge, C., Goh, N., Hopkins, P., Mahar, A., et al (2017). Determinants and outcomes of prolonged anxiety and depression in idiopathic pulmonary fibrosis. European Respiratory Journal, 50(2), pii: 1700168. [More Information]
  • Barnet, M., O'Toole, S., Horvath, L., Selinger, C., Yu, B., Ng, C., Boyer, M., Cooper, W., Kao, S. (2017). EGFR–Co-Mutated Advanced NSCLC and Response to EGFR Tyrosine Kinase Inhibitors. Journal of Thoracic Oncology, 12(3), 585-590. [More Information]

2016

  • Kao, S., Kirschner, M., Cooper, W., Tran, T., Burgers, S., Wright, C., Korse, T., van den Broek, D., Edelman, J., Vallely, M., McCaughan, B., Pavlakis, N., Clarke, S., van Zandwijk, N., Reid, G., et al (2016). A proteomics-based approach identifies secreted protein acidic and rich in cysteine as a prognostic biomarker in malignant pleural mesothelioma. British Journal of Cancer, 114(5), 524-531. [More Information]
  • Tran, T., Selinger, C., Kohonen-Corish, M., McCaughan, B., Kennedy, C., O'Toole, S., Cooper, W. (2016). Alterations of MET Gene Copy Number and Protein Expression in Primary Non-Small-Cell Lung Cancer and Corresponding Nodal Metastases. Clinical Lung Cancer, 17(1), 30-38. [More Information]
  • Vargas, A., Selinger, C., Satgunaseelan, L., Cooper, W., Gupta, R., Stalley, P., Brown, W., Soper, J., Schatz, J., Boyle, R., Tattersall, M., Bhadri, V., Scolyer, R., Karim, R., McCarthy, S., O'Toole, S., et al (2016). Atypical Ewing sarcoma breakpoint region 1 fluorescence in-situ hybridization signal patterns in bone and soft tissue tumours: diagnostic experience with 135 cases. Histopathology, 69(6), 1000-1011. [More Information]

2015

  • Kao, S., Fulham, M., Wong, K., Cooper, W., Brahmbhatt, H., MacDiarmid, J., Pattison, S., Sagong, J., Huynh, Y., Leslie, F., Pavlakis, N., Clarke, S., Boyer, M., Reid, G., van Zandwijk, N. (2015). A significant metabolic and radiological response after a novel targeted microRNA-based treatment approach in malignant pleural mesothelioma. American Journal of Respiratory and Critical Care Medicine, 191(12), 1467-1469. [More Information]
  • Luk, P., Yu, B., Ng, C., Mercorella, B., Selinger, C., Lum, T., Kao, S., O'Toole, S., Cooper, W. (2015). BRAF mutations in non-small cell lung cancer. Translational Lung Cancer Research, 4(2), 142-148. [More Information]
  • Selinger, C., Cooper, W., Lum, T., McNeil, C., Morey, A., Waring, P., Amanuel, B., Millward, M., Peverall, J., Van Vliet, C., Pavlakis, N., Gill, A., et al (2015). Equivocal ALK fluorescence in-situ hybridization (FISH) cases may benefit from ancillary ALK FISH probe testing. Histopathology, 67(5), 654-663. [More Information]

2014

  • Tran, T., Selinger, C., Yu, B., Ng, C., Kohonen-Corish, M., McCaughan, B., Kennedy, C., O'Toole, S., Cooper, W. (2014). Alterations of insulin-like growth factor-1 receptor gene copy number and protein expression are common in non-small cell lung cancer. Journal of Clinical Pathology, 67(11), 985-991. [More Information]
  • Moodley, Y., Goh, N., Glaspole, I., Macansh, S., Walters, E., Chapman, S., Hopkins, P., Reynolds, P., Zappala, C., Cooper, W., Mahar, A., Corte, T., et al (2014). Australian Idiopathic Pulmonary Fibrosis Registry: Vital lessons from a national prospective collaborative project. Respirology, 19(7), 1088-1091. [More Information]
  • Carlino, M., Haydu, L., Kakavand, H., Menzies, A., Hamilton, A., Yu, B., Ng, C., Cooper, W., Thompson, J., Kefford, R., O'Toole, S., Scolyer, R., Long, G. (2014). Correlation of BRAF and NRAS mutation status with outcome, site of distant metastasis and response to chemotherapy in metastatic melanoma. British Journal of Cancer, 111(2), 292-299. [More Information]

2013

  • Cooper, W., Yu, B., Yip, P., Ng, C., Lum, T., Farzin, M., Trent, R., Mercorella, B., Clarkson, A., Kohonen-Corish, M., Horvath, L., Kench, J., McCaughan, B., Gill, A., O'Toole, S. (2013). EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma. Journal of Clinical Pathology, 66(9), 744-748. [More Information]
  • Tran, T., Selinger, C., Kohonen-Corish, M., McCaughan, B., Kennedy, C., O'Toole, S., Cooper, W. (2013). Fibroblast growth factor receptor 1 (FGFR1) copy number is an independent prognostic factor in non-small cell lung cancer. Lung Cancer, 81(3), 462-467. [More Information]
  • Cooper, W., Lam, D., O'Toole, S., Minna, J. (2013). Molecular biology of lung cancer. Journal of Thoracic Disease, 5(S5), S479-S490. [More Information]

2012

  • Poursoltana, P., Currey, N., Pangon, L., van Kralingen, C., Selinger, C., Mahar, A., Cooper, W., Kennedy, C., McCaughan, B., Trent, R., et al (2012). Loss of heterozygosity of the Mutated in Colorectal Cancer gene is not associated with promoter methylation in non-small cell lung cancer. Lung Cancer, 77(2), 272-276. [More Information]
  • Wang, Y., Sebaratnam, D., Wong, J., Cooper, W., Wyburn, K., Eris, J. (2012). Urethral Stricture Caused by Schistosomiasis in a Renal Transplant Recipient. Nephrology, 17(2), 197-198. [More Information]

2011

  • Lau, E., Cooper, W., Bye, P., Yan, K. (2011). Difficult asthma and Churg-Strauss-like syndrome: A cautionary tale. Respirology, 16(1), 180-181. [More Information]
  • Cooper, W., O'Toole, S., Boyer, M., Horvath, L., Mahar, A. (2011). What's new in non-small cell lung cancer for pathologists: the importance of accurate subtyping, EGFR mutations and ALK rearrangements. Pathology, 43(2), 103-115. [More Information]

2004

  • Cooper, W., Shingde, M., Lee, V., Allan, R., Wills, E., Harper, C. (2004). "Rhabdoid Meningioma" Lacking Malignant Features. Report Of Two Cases. Clinical Neuropathology, 23(1), 16-20.